Linear Models for Microarray Data

Bioconductor version: Release (2.11)

Data analysis, linear models and differential expression for microarray data.

Author: Gordon Smyth with contributions from Matthew Ritchie, Jeremy Silver, James Wettenhall, Natalie Thorne, Mette Langaas, Egil Ferkingstad, Marcus Davy, Francois Pepin, Dongseok Choi, Davis McCarthy, Di Wu, Alicia Oshlack, Carolyn de Graaf, Yifang Hu, Wei Shi and Belinda Phipson.

Maintainer: Gordon Smyth <smyth at>

To install this package, start R and enter:


To cite this package in a publication, start R and enter:



PDF R Script Limma Vignette
PDF usersguide.pdf
HTML index.html
PDF   Reference Manual
Text   NEWS


biocViews Bioinformatics, DataImport, DifferentialExpression, Microarray, MultipleComparisons, OneChannel, Preprocessing, QualityControl, Software, TimeCourse, TwoChannel
Version 3.14.4
In Bioconductor since BioC 1.6 (R-2.1) or earlier
License GPL (>=2)
Depends R (>= 2.3.0), methods
Suggests affy, MASS,, splines, statmod (>= 1.2.2), vsn
System Requirements
Depends On Me a4Base, AffyExpress, affylmGUI, Agi4x44PreProcess, attract, birta, CALIB, CCl4, cghMCR, ChIPpeakAnno, codelink, convert, Cormotif, coRNAi, edgeR, ExiMiR, HTqPCR, inSilicoMerging, limmaGUI, lmdme, maDB, maigesPack, marray, MmPalateMiRNA, nem, PADOG, qpcrNorm, Ringo, snapCGH, TurboNorm
Imports Me affycoretools, ArrayExpress, arrayQuality, arrayQualityMetrics, ArrayTools, attract, beadarray, BeadArrayUseCases, betr, CALIB, CancerMutationAnalysis, charm, ChIPpeakAnno, explorase, gCMAP, GeneSelectMMD, GeneSelector, GGBase, HTqPCR, iChip, maSigPro, minfi, MmPalateMiRNA, OLIN, PADOG, phenoTest, Ringo, RNAinteract, RNAither, RTopper, snapCGH, SSPA, timecourse, tweeDEseq, vsn
Suggests Me ABarray, beadarraySNP, BiocCaseStudies, BioNet, Category, categoryCompare, CMA, coGPS, dyebias, GeneSelector, GEOquery, GSRI, GSVA, Heatplus, inSilicoDb, les, lumi, methylumi, MLP, oligo, oneChannelGUI, PGSEA, plw, PREDA, puma, Rcade, RTopper, rtracklayer, virtualArray

Package Downloads

Package Source limma_3.14.4.tar.gz
Windows Binary (32- & 64-bit)
MacOS 10.5 (Leopard) limma_3.14.4.tgz
Package Downloads Report Download Stats

Mailing Lists »

Post questions about Bioconductor packages to our mailing lists. Read the posting guide before posting!

Fred Hutchinson Cancer Research Center