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This package is for version 2.8 of Bioconductor; for the stable, up-to-date release version, see limma.

Linear Models for Microarray Data

Bioconductor version: 2.8

Data analysis, linear models and differential expression for microarray data.

Author: Gordon Smyth with contributions from Matthew Ritchie, Jeremy Silver, James Wettenhall, Natalie Thorne, Mette Langaas, Egil Ferkingstad, Marcus Davy, Francois Pepin, Dongseok Choi, Davis McCarthy, Di Wu, Alicia Oshlack, Carolyn de Graaf, Yifang Hu, Wei Shi and Belinda Phipson.

Maintainer: Gordon Smyth <smyth at>

Citation (from within R, enter citation("limma")):


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PDF limma.pdf
PDF usersguide.pdf
PDF   Reference Manual


biocViews Bioinformatics, DataImport, DifferentialExpression, Microarray, MultipleComparisons, OneChannel, Preprocessing, QualityControl, Software, TimeCourse, TwoChannel
Version 3.8.3
In Bioconductor since BioC 1.6 (R-2.1) or earlier (> 11 years)
License LGPL
Depends R (>= 2.3.0), methods
Suggests affy, MASS,, splines, statmod (>= 1.2.2), vsn
Depends On Me a4Base, AffyExpress, affylmGUI, Agi4x44PreProcess, AgiMicroRna, attract, CALIB, CCl4, cghMCR, ChIPpeakAnno, clippda, codelink, convert, coRNAi, HTqPCR, limmaGUI, LVSmiRNA, maDB, maigesPack, marray, nem, oneChannelGUI, qpcrNorm, Ringo, RMAGEML, RTools4TB, snapCGH, TurboNorm
Imports Me affycoretools, ArrayExpress, arrayQuality, arrayQualityMetrics, ArrayTools, attract, beadarray, betr, CALIB, ChIPpeakAnno, edgeR, explorase, GeneSelector, HTqPCR, iChip, maSigPro, OLIN, PatientGeneSets, phenoTest, Ringo, RNAinteract, RNAither, snapCGH, SSPA, timecourse, vsn
Suggests Me ABarray, beadarraySNP, BiocCaseStudies, BioNet, Category, CMA, dyebias, GeneSelector, GEOquery, GSRI, GSVA, les, lumi, methylumi, MLP, oligo, PGSEA, plw, puma, rtracklayer
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Package Source limma_3.8.3.tar.gz
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