Disease Ontology Semantic and Enrichment analysis

Bioconductor version: 2.10

Implemented five methods proposed by Resnik, Schlicker, Jiang, Lin and Wang respectively for measuring DO semantic similarities, and hypergeometric test for enrichment analysis.

Author: Guangchuang Yu, Li-Gen Wang

Maintainer: Guangchuang Yu <guangchuangyu at>

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PDF R Script An introduction to DOSE
PDF   Reference Manual
Text   NEWS


biocViews Annotation, Bioinformatics, Software
Depends R (>= 2.10)
Imports methods, plyr, qvalue, stats4, AnnotationDbi, DO.db,, igraph, scales, ggplot2, graphics
Suggests clusterProfiler, GOSemSim, ReactomePA
System Requirements
License Artistic-2.0
Depends On Me
Imports Me clusterProfiler
Suggests Me GOSemSim, ReactomePA
Version 1.2.1
Since Bioconductor 2.9 (R-2.14)

Package Downloads

Package Source DOSE_1.2.1.tar.gz
Windows Binary (32- & 64-bit)
MacOS 10.5 (Leopard) binary DOSE_1.2.1.tgz
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Fred Hutchinson Cancer Research Center