Analysis of cell-based screens - revised version of cellHTS

Bioconductor version: Release (2.11)

This package provides tools for the analysis of high-throughput assays that were performed in 384-well microtitre plate (or analogous) formats. The functionality includes data import and management, normalisation, quality assessment, replicate summarisation and statistical scoring. A webpage that provides a detailed graphical overview over the data and analysis results is produced. In our work, we have applied the package to RNAi screens on fly and human cells, and for screens of yeast libraries. See ?cellHTS2 for a brief introduction.

Author: Ligia Bras, Wolfgang Huber <whuber at embl.de>, Michael Boutros <m.boutros at dkfz.de>, Gregoire Pau <gpau at embl.de>, Florian Hahne <florian.hahne at novartis.com>

Maintainer: Joseph Barry <joseph.barry at embl.de>

To install this package, start R and enter:


To cite this package in a publication, start R and enter:



PDF R Script Main vignette (complete version): End-to-end analysis of cell-based screens
PDF R Script Main vignette: End-to-end analysis of cell-based screens
PDF R Script Supplement: enhancer-suppressor screens
PDF R Script Supplement: multi-channel assays
PDF   Reference Manual


biocViews CellBasedAssays, Preprocessing, Software, Visualization
Version 2.22.0
In Bioconductor since BioC 2.1 (R-2.6)
License Artistic-2.0
Depends R (>= 2.10), RColorBrewer, Biobase, methods, genefilter, splots, vsn, hwriter, locfit, grid
Imports prada, GSEABase, Category, stats4
System Requirements
URL http://www.dkfz.de/signaling, http://www.ebi.ac.uk/huber
Depends On Me coRNAi, imageHTS, staRank
Imports Me HTSanalyzeR, RNAinteract
Suggests Me

Package Downloads

Package Source cellHTS2_2.22.0.tar.gz
Windows Binary cellHTS2_2.22.0.zip (32- & 64-bit)
MacOS 10.5 (Leopard) cellHTS2_2.22.0.tgz
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