DOI: 10.18129/B9.bioc.seqbias    

This package is for version 3.9 of Bioconductor; for the stable, up-to-date release version, see seqbias.

Estimation of per-position bias in high-throughput sequencing data

Bioconductor version: 3.9

This package implements a model of per-position sequencing bias in high-throughput sequencing data using a simple Bayesian network, the structure and parameters of which are trained on a set of aligned reads and a reference genome sequence.

Author: Daniel Jones <dcjones at>

Maintainer: Daniel Jones <dcjones at>

Citation (from within R, enter citation("seqbias")):


To install this package, start R (version "3.6") and enter:

if (!requireNamespace("BiocManager", quietly = TRUE))


For older versions of R, please refer to the appropriate Bioconductor release.


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PDF R Script Assessing and Adjusting for Technical Bias in High Throughput Sequencing Data
PDF   Reference Manual


biocViews Sequencing, Software
Version 1.32.0
In Bioconductor since BioC 2.8 (R-2.13) (8.5 years)
License LGPL-3
Depends R (>= 3.0.2), GenomicRanges(>= 0.1.0), Biostrings(>= 2.15.0), methods
LinkingTo Rhtslib(>= 1.15.3)
Suggests Rsamtools, ggplot2
Depends On Me ReQON
Imports Me
Suggests Me
Links To Me
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