To install this package, start R and enter:

## try http:// if https:// URLs are not supported
source("https://bioconductor.org/biocLite.R")
biocLite("IHW")

In most cases, you don't need to download the package archive at all.

IHW

   

This package is for version 3.3 of Bioconductor; for the stable, up-to-date release version, see IHW.

Independent Hypothesis Weighting

Bioconductor version: 3.3

Independent hypothesis weighting (IHW) is a multiple testing procedure that increases power compared to the method of Benjamini and Hochberg by assigning data-driven weights to each hypothesis. The input to IHW is a two-column table of p-values and covariates. The covariate can be any continuous-valued or categorical variable that is thought to be informative on the statistical properties of each hypothesis test, while it is independent of the p-value under the null hypothesis.

Author: Nikos Ignatiadis [aut, cre], Wolfgang Huber [aut]

Maintainer: Nikos Ignatiadis <nikos.ignatiadis01 at gmail.com>

Citation (from within R, enter citation("IHW")):

Installation

To install this package, start R and enter:

## try http:// if https:// URLs are not supported
source("https://bioconductor.org/biocLite.R")
biocLite("IHW")

Documentation

HTML Introduction to IHW
PDF   Reference Manual

Details

biocViews ExperimentData, MultipleComparison, RNASeq
Version 0.99.14
In Bioconductor since BioC 3.3 (R-3.3) (< 6 months)
License Artistic-2.0
Depends R (>= 3.3.0)
Imports methods, slam, lpsymphony, fdrtool, BiocGenerics
LinkingTo
Suggests ggplot2, scales, DESeq, DESeq2, airway, testthat, Matrix, BiocStyle, knitr, rmarkdown, devtools
SystemRequirements
Enhances
URL
Depends On Me IHWpaper
Imports Me
Suggests Me DESeq2
Build Report  

Package Archives

Follow Installation instructions to use this package in your R session.

Package Source IHW_0.99.14.tar.gz
Windows Binary
Mac OS X 10.9 (Mavericks)
Subversion source (username/password: readonly)
Package Short Url http://bioconductor.org/packages/IHW/
Package Downloads Report Download Stats

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