DOI: 10.18129/B9.bioc.sSNAPPY  

This package is for version 3.17 of Bioconductor; for the stable, up-to-date release version, see sSNAPPY.

Single Sample directioNAl Pathway Perturbation analYsis

Bioconductor version: 3.17

A single sample pathway perturbation testing method for RNA-seq data. The method propagates changes in gene expression down gene-set topologies to compute single-sample directional pathway perturbation scores that reflect potential direction of change. Perturbation scores can be used to test significance of pathway perturbation at both individual-sample and treatment levels.

Author: Wenjun Liu [aut, cre] , Stephen Pederson [aut]

Maintainer: Wenjun Liu <wenjun.liu at>

Citation (from within R, enter citation("sSNAPPY")):


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biocViews GeneExpression, GeneSetEnrichment, GeneSignaling, Software
Version 1.4.6
In Bioconductor since BioC 3.15 (R-4.2) (1.5 years)
License GPL-3
Depends R (>= 4.3.0), ggplot2
Imports dplyr (>= 1.1), magrittr, rlang, stats, graphite, tibble, ggraph, igraph, reshape2,, SummarizedExperiment, edgeR, methods, ggforce, pheatmap, utils, stringr, gtools, tidyr
Suggests BiocManager, BiocStyle, colorspace, cowplot, DT, htmltools, knitr, pander, patchwork, rmarkdown, spelling, testthat (>= 3.0.0), tidyverse
SystemRequirements C++11
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