DOI: 10.18129/B9.bioc.EpiDISH  

This package is for version 3.17 of Bioconductor; for the stable, up-to-date release version, see EpiDISH.

Epigenetic Dissection of Intra-Sample-Heterogeneity

Bioconductor version: 3.17

EpiDISH is a R package to infer the proportions of a priori known cell-types present in a sample representing a mixture of such cell-types. Right now, the package can be used on DNAm data of whole blood, generic epithelial tissue and breast tissue. Besides, the package provides a function that allows the identification of differentially methylated cell-types and their directionality of change in Epigenome-Wide Association Studies.

Author: Andrew E. Teschendorff [aut], Shijie C. Zheng [aut, cre]

Maintainer: Shijie C. Zheng <shijieczheng at gmail.com>

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biocViews DNAMethylation, DifferentialMethylation, Epigenetics, ImmunoOncology, MethylationArray, Software
Version 2.16.0
In Bioconductor since BioC 3.6 (R-3.4) (6 years)
License GPL-2
Depends R (>= 4.1)
Imports MASS, e1071, quadprog, parallel, stats, matrixStats, stringr, locfdr, Matrix
Suggests roxygen2, GEOquery, BiocStyle, knitr, rmarkdown, Biobase, testthat
URL https://github.com/sjczheng/EpiDISH
BugReports https://github.com/sjczheng/EpiDISH/issues
Depends On Me TOAST
Imports Me
Suggests Me FlowSorted.Blood.EPIC, planet
Links To Me
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Source Package EpiDISH_2.16.0.tar.gz
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