DOI: 10.18129/B9.bioc.DSS    

This package is for version 3.12 of Bioconductor; for the stable, up-to-date release version, see DSS.

Dispersion shrinkage for sequencing data

Bioconductor version: 3.12

DSS is an R library performing differntial analysis for count-based sequencing data. It detectes differentially expressed genes (DEGs) from RNA-seq, and differentially methylated loci or regions (DML/DMRs) from bisulfite sequencing (BS-seq). The core of DSS is a new dispersion shrinkage method for estimating the dispersion parameter from Gamma-Poisson or Beta-Binomial distributions.

Author: Hao Wu<hao.wu at emory.edu>, Hao Feng<hxf155 at case.edu>

Maintainer: Hao Wu <hao.wu at emory.edu>, Hao Feng <hxf155 at case.edu>

Citation (from within R, enter citation("DSS")):


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HTML R Script The DSS User's Guide
PDF   Reference Manual
Text   NEWS


biocViews DNAMethylation, DifferentialExpression, DifferentialMethylation, GeneExpression, RNASeq, Sequencing, Software
Version 2.38.0
In Bioconductor since BioC 2.11 (R-2.15) (8.5 years)
License GPL
Depends R (>= 3.3), methods, Biobase, BiocParallel, bsseq
Imports utils, graphics, stats, splines, DelayedArray
Suggests BiocStyle, knitr, rmarkdown
Depends On Me
Imports Me DMRcate, kissDE, metaseqR2, MethCP, methylSig
Suggests Me biscuiteer, methrix, NanoMethViz, PROPER
Links To Me
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Follow Installation instructions to use this package in your R session.

Source Package DSS_2.38.0.tar.gz
Windows Binary DSS_2.38.0.zip (32- & 64-bit)
macOS 10.13 (High Sierra) DSS_2.38.0.tgz
Source Repository git clone https://git.bioconductor.org/packages/DSS
Source Repository (Developer Access) git clone git@git.bioconductor.org:packages/DSS
Package Short Url https://bioconductor.org/packages/DSS/
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