DropletUtils

DOI: 10.18129/B9.bioc.DropletUtils    

This package is for version 3.10 of Bioconductor; for the stable, up-to-date release version, see DropletUtils.

Utilities for Handling Single-Cell Droplet Data

Bioconductor version: 3.10

Provides a number of utility functions for handling single-cell (RNA-seq) data from droplet technologies such as 10X Genomics. This includes data loading from count matrices or molecule information files, identification of cells from empty droplets, removal of barcode-swapped pseudo-cells, and downsampling of the count matrix.

Author: Aaron Lun [aut, cre], Jonathan Griffiths [ctb], Davis McCarthy [ctb]

Maintainer: Aaron Lun <infinite.monkeys.with.keyboards at gmail.com>

Citation (from within R, enter citation("DropletUtils")):

Installation

To install this package, start R (version "3.6") and enter:

if (!requireNamespace("BiocManager", quietly = TRUE))
    install.packages("BiocManager")

BiocManager::install("DropletUtils")

For older versions of R, please refer to the appropriate Bioconductor release.

Documentation

To view documentation for the version of this package installed in your system, start R and enter:

browseVignettes("DropletUtils")

 

HTML R Script Utilities for handling droplet-based single-cell RNA-seq data
PDF   Reference Manual
Text   NEWS

Details

biocViews Coverage, DataImport, GeneExpression, ImmunoOncology, RNASeq, Sequencing, SingleCell, Software, Transcriptomics
Version 1.6.1
In Bioconductor since BioC 3.7 (R-3.5) (2 years)
License GPL-3
Depends SingleCellExperiment
Imports S4Vectors, BiocParallel, Rcpp, Matrix, methods, utils, stats, edgeR, rhdf5, HDF5Array, R.utils, dqrng
LinkingTo Rcpp, beachmat, Rhdf5lib, BH, dqrng
Suggests testthat, beachmat, knitr, BiocStyle, rmarkdown
SystemRequirements C++11, GNU make
Enhances
URL
Depends On Me
Imports Me
Suggests Me BUSpaRse, scater, splatter
Links To Me
Build Report  

Package Archives

Follow Installation instructions to use this package in your R session.

Source Package DropletUtils_1.6.1.tar.gz
Windows Binary DropletUtils_1.6.1.zip
Mac OS X 10.11 (El Capitan) DropletUtils_1.6.1.tgz
Source Repository git clone https://git.bioconductor.org/packages/DropletUtils
Source Repository (Developer Access) git clone git@git.bioconductor.org:packages/DropletUtils
Package Short Url https://bioconductor.org/packages/DropletUtils/
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