DOI: 10.18129/B9.bioc.CAMTHC    

This package is deprecated. It will probably be removed from Bioconductor. Please refer to the package end-of-life guidelines for more information.

This package is for version 3.10 of Bioconductor. This package has been removed from Bioconductor. For the last stable, up-to-date release version, see CAMTHC (renamed to debCAM).

Convex Analysis of Mixtures for Tissue Heterogeneity Characterization

Bioconductor version: 3.10

An R package for tissue heterogeneity characterization by convex analysis of mixtures (CAM). It provides basic functions to perform unsupervised deconvolution on mixture expression profiles by CAM and some auxiliary functions to help understand the subpopulation-specific results. It also implements functions to perform supervised deconvolution based on prior knowledge of molecular markers, S matrix or A matrix. Combining molecular markers from CAM and from prior knowledge can achieve semi-supervised deconvolution of mixtures.

Author: Lulu Chen <luluchen at>

Maintainer: Lulu Chen <luluchen at>

Citation (from within R, enter citation("CAMTHC")):


To install this package, start R (version "3.6") and enter:

if (!requireNamespace("BiocManager", quietly = TRUE))


For older versions of R, please refer to the appropriate Bioconductor release.


To view documentation for the version of this package installed in your system, start R and enter:



HTML R Script CAMTHC User Manual
PDF   Reference Manual
Text   NEWS


biocViews CellBiology, GeneExpression, Software
Version 1.4.0
In Bioconductor since BioC 3.8 (R-3.5) (1.5 years)
License GPL-2
Depends R (>= 3.5)
Imports methods, rJava, BiocParallel, stats, Biobase, SummarizedExperiment, corpcor, geometry, NMF, nnls, DMwR, pcaPP, apcluster, graphics
Suggests knitr, rmarkdown, BiocStyle, testthat, GEOquery, rgl
SystemRequirements Java (>= 1.8)
Depends On Me
Imports Me
Suggests Me
Links To Me
Build Report  

Package Archives

Follow Installation instructions to use this package in your R session.

Source Package CAMTHC_1.4.0.tar.gz
Windows Binary (32- & 64-bit)
Mac OS X 10.11 (El Capitan) CAMTHC_1.4.0.tgz
Source Repository git clone
Source Repository (Developer Access) git clone
Package Short Url
Package Downloads Report Download Stats

Documentation »


R / CRAN packages and documentation

Support »

Please read the posting guide. Post questions about Bioconductor to one of the following locations: