A normalization method for Copy Number Aberration in cancer samples.

Bioconductor version: 2.9

Performs ratio, GC content correction and normalization of data obtained using low coverage (one read every 100-10,000 bp) high troughput sequencing. It performs a "discrete" normalization looking for the ploidy of the genome. It will also provide tumour content if at least two ploidy states can be found.

Author: Stefano Berri <s.berri at> or <s.berri at> and Arief Gusnanto <a.gusnanto at>.

Maintainer: Stefano Berri <s.berri at>

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PDF CNAnorm.pdf
PDF   Reference Manual
Text   NEWS


biocViews Bioinformatics, HighThroughputSequencing, CopyNumberVariants, Sequencing, Cancer, Lung
Depends R (>= 2.10.1), DNAcopy, methods
Imports methods
System Requirements
License GPL-2
Depends On Me
Imports Me
Suggests Me
Version 1.0.0
Since Bioconductor 2.9 (R-2.14)

Package Downloads

Package Source CNAnorm_1.0.0.tar.gz
Windows Binary (32- & 64-bit)
MacOS 10.5 (Leopard) binary CNAnorm_1.0.0.tgz
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Fred Hutchinson Cancer Research Center