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Analysis and quantitation of isobarically tagged MSMS proteomics data

Bioconductor version: 2.14

isobar provides methods for preprocessing, normalization, and report generation for the analysis of quantitative mass spectrometry proteomics data labeled with isobaric tags, such as iTRAQ and TMT. Features modules for integrating and validating PTM-centric datasets (isobar-PTM). More information on

Author: Florian P Breitwieser <fbreitwieser at> and Jacques Colinge <jcolinge at>, with contributions from Xavier Robin <xavier.robin at> and Florent Gluck <florent.gluck at>

Maintainer: Florian P Breitwieser <fbreitwieser at>

Citation (from within R, enter citation("isobar")):


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PDF R Script isobar for developers
PDF R Script isobar for quantification of PTM datasets
PDF R Script isobar package for iTRAQ and TMT protein quantification
PDF   Reference Manual
Text   NEWS


biocViews Bioinformatics, MassSpectrometry, MultipleComparisons, Proteomics, QualityControl, Software
Version 1.10.0
In Bioconductor since BioC 2.9 (R-2.14)
License LGPL-2
Depends R (>= 2.10.0), Biobase, stats, methods, plyr
Imports distr
Suggests MSnbase, OrgMassSpecR, XML, biomaRt, ggplot2, RJSONIO, Hmisc, gplots, RColorBrewer, gridExtra, limma, boot, distr, Rgbp, DBI, MASS
System Requirements
Depends On Me
Imports Me
Suggests Me RforProteomics

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Package Source isobar_1.10.0.tar.gz
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