source("http://bioconductor.org/biocLite.R")
biocLite("TargetScore")

TargetScore

TargetScore: Infer microRNA targets using microRNA-overexpression data and sequence information

Bioconductor version: 2.13

Infer the posterior distributions of microRNA targets by probabilistically modelling the likelihood microRNA-overexpression fold-changes and sequence-based scores. Variaitonal Bayesian Gaussian mixture model (VB-GMM) is applied to log fold-changes and sequence scores to obtain the posteriors of latent variable being the miRNA targets. The final targetScore is computed as the sigmoid-transformed fold-change weighted by the averaged posteriors of target components over all of the features.

Author: Yue Li

Maintainer: Yue Li <yueli at cs.toronto.edu>

Installation

To install this package, start R and enter:

source("http://bioconductor.org/biocLite.R")
biocLite("TargetScore")

Documentation

To view documentation for the version of this package installed in your system, start R and enter:

browseVignettes("TargetScore")

 

PDF	R Script	TargetScore: Infer microRNA targets using microRNA-overexpression data and sequence information
PDF		Reference Manual
Text		NEWS

Details

biocViews	Software, microRNA
Version	1.0.0
In Bioconductor since	BioC 2.13 (R-3.0)
License	GPL-2
Depends	pracma, Matrix
Imports
Suggests	TargetScoreData, gplots, Biobase, GEOquery
System Requirements
URL	http://www.cs.utoronto.ca/~yueli/software.html
Depends On Me
Imports Me
Suggests Me	TargetScoreData

Package Archives

Follow Installation instructions to use this package in your R session.

Package Source	TargetScore_1.0.0.tar.gz
Windows Binary	TargetScore_1.0.0.zip (32- & 64-bit)
Mac OS X 10.6 (Snow Leopard)	TargetScore_1.0.0.tgz
Browse/checkout source	(username/password: readonly)
Package Downloads Report	Download Stats