DSS

Dispersion shrinakge for sequencing data.

Bioconductor version: Release (2.12)

DSS is an R library performing the differential expression analysis for RNA-seq count data. DSS implements a new dispersion shrinkage method to estimate the gene-specific biological variance. Extensive simulation results showed that DSS performs favorabily compared to DESeq and edgeR when the variation of biological variances is large.

Author: Hao Wu <hao.wu at emory.edu>

Maintainer: Hao Wu <hao.wu at emory.edu>

To install this package, start R and enter:

    source("http://bioconductor.org/biocLite.R")
    biocLite("DSS")

To cite this package in a publication, start R and enter:

    citation("DSS")

Documentation

PDF R Script Differential expression for RNA-seq data with dispersion shrinkage
PDF   Reference Manual
Text   NEWS

Details

biocViews ChIPseq, DifferentialExpression, HighThroughputSequencing, RNAseq, Software
Version 1.4.0
In Bioconductor since BioC 2.11 (R-2.16)
License GPL
Depends Biobase, locfdr
Imports methods
Suggests
System Requirements
URL
Depends On Me
Imports Me
Suggests Me

Package Downloads

Package Source DSS_1.4.0.tar.gz
Windows Binary DSS_1.4.0.zip (32- & 64-bit)
Mac OS X 10.6 (Snow Leopard) DSS_1.4.0.tgz
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