DESeq2

Differential gene expression analysis based on the negative binomial distribution

Bioconductor version: Release (2.12)

Estimate variance-mean dependence in count data from high-throughput sequencing assays and test for differential expression based on a model using the negative binomial distribution

Author: Michael Love (MPIMG Berlin), Simon Anders, Wolfgang Huber (EMBL Heidelberg)

Maintainer: Michael Love <michaelisaiahlove at gmail.com>

To install this package, start R and enter:

    source("http://bioconductor.org/biocLite.R")
    biocLite("DESeq2")

To cite this package in a publication, start R and enter:

    citation("DESeq2")

Documentation

PDF R Script Analyzing RNA-Seq data with the "DESeq2" package
PDF vst.pdf
PDF   Reference Manual
Text   NEWS

Details

biocViews ChIPseq, DifferentialExpression, HighThroughputSequencing, RNAseq, SAGE, Software
Version 1.0.19
In Bioconductor since BioC 2.13 (R-2.18)
License GPL (>= 3)
Depends GenomicRanges, IRanges, Biobase, lattice, Rcpp (>= 0.10.1), RcppArmadillo (>= 0.3.4.4)
Imports GenomicRanges, IRanges, Biobase, locfit, genefilter, methods, RColorBrewer, lattice
Suggests parathyroidSE, pasilla(>= 0.2.10), vsn, gplots
System Requirements
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Imports Me HTSFilter
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Package Downloads

Package Source DESeq2_1.0.19.tar.gz
Windows Binary DESeq2_1.0.19.zip (32- & 64-bit)
Mac OS X 10.6 (Snow Leopard) DESeq2_1.0.19.tgz
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