Bioconductor version: Release (2.12)
This package provides functions for the integrated analysis of protein-protein interaction networks and the detection of functional modules. Different datasets can be integrated into the network by assigning p-values of statistical tests to the nodes of the network. E.g. p-values obtained from the differential expression of the genes from an Affymetrix array are assigned to the nodes of the network. By fitting a beta-uniform mixture model and calculating scores from the p-values, overall scores of network regions can be calculated and an integer linear programming algorithm identifies the maximum scoring subnetwork.
Author: Marcus Dittrich and Daniela Beisser
Maintainer: Marcus Dittrich <marcus.dittrich at biozentrum.uni-wuerzburg.de>
To install this package, start R and enter:
source("http://bioconductor.org/biocLite.R") biocLite("BioNet")
To cite this package in a publication, start R and enter:
citation("BioNet")
R Script | BioNet Tutorial | |
bum1.pdf | ||
bum2.pdf | ||
cytoscape.pdf | ||
prec_recall_large.pdf | ||
prec_recall_small.pdf | ||
Tutorial-3dplot.pdf | ||
Reference Manual |
biocViews | DataImport, DifferentialExpression, GeneExpression, GraphsAndNetworks, Microarray, NetworkAnalysis, NetworkEnrichment, Software |
Version | 1.18.0 |
In Bioconductor since | BioC 2.7 (R-2.12) |
License | GPL (>= 2) |
Depends | R (>= 2.10.0), Biobase, graph, RBGL |
Imports | igraph0, AnnotationDbi |
Suggests | rgl, impute, DLBCL, genefilter, xtable, ALL, limma, hgu95av2.db, XML |
System Requirements | |
URL | http://bionet.bioapps.biozentrum.uni-wuerzburg.de/ |
Depends On Me | |
Imports Me | HTSanalyzeR |
Suggests Me |
Package Source | BioNet_1.18.0.tar.gz |
Windows Binary | BioNet_1.18.0.zip (32- & 64-bit) |
Mac OS X 10.6 (Snow Leopard) | BioNet_1.18.0.tgz |
Package Downloads Report | Download Stats |
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