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HTAN

This is the development version of HTAN; to use it, please install the devel version of Bioconductor.

Query and Retrieve Human Tumor Atlas Network (HTAN) Open-Access Data


Bioconductor version: Development (3.24)

A client for the open-access data of the Human Tumor Atlas Network (HTAN), Phase 1. File, biospecimen, clinical and provenance metadata are queried locally from a versioned parquet snapshot of the ISB-CGC HTAN BigQuery release tables, through DuckDB and dbplyr, with no Google account. Open-access files are downloaded from the CRDC General Commons (anonymous GA4GH DRS) or Synapse (personal access token), and common HTAN file formats are read into Bioconductor classes such as SingleCellExperiment, SpatialExperiment and MultiAssayExperiment.

Author: Sean Davis [aut, cre] ORCID iD ORCID: 0000-0002-8991-6458 , National Cancer Institute [fnd] (Grant U24CA289073)

Maintainer: Sean Davis <seandavi at gmail.com>

Citation (from within R, enter citation("HTAN")):

Sean Davis. HTAN: Query and Retrieve Human Tumor Atlas Network (HTAN) Open-Access Data. doi:10.18129/B9.bioc.HTAN, R package version 0.99.1, https://bioconductor.org/packages/HTAN.

Generated from the package metadata; it may differ from the package's own citation.

Installation

To install this package, start R (version "4.6") and enter:

if (!require("BiocManager", quietly = TRUE))
    install.packages("BiocManager")

## The following initializes the development version of Bioconductor
BiocManager::install(version = "devel")

BiocManager::install("HTAN")

For older versions of R, please refer to the appropriate Bioconductor release.

Documentation

To view documentation for the version of this package installed in your system, start R and enter:

browseVignettes("HTAN")
analysis-workflow.html HTML R Script
atlas-overview.html HTML R Script
data-model.html HTML R Script
HTAN.html HTML R Script
Reference ManualPDF

Details

biocViews BiomedicalInformatics, DataImport, DataRepresentation, SingleCell, Software, Spatial, ThirdPartyClient, Transcriptomics
Version0.99.1
In Bioconductor sinceBioC 3.24 (R-4.6)
License MIT + file LICENSE
Depends R (>= 4.5.0)
Imports BiocFileCache, DBI, dbplyr, dplyr, duckdb, httr2, jsonlite, methods, MultiAssayExperiment, rlang, S4Vectors, SingleCellExperiment, SpatialExperiment, stats, SummarizedExperiment, tibble, tools, utils
System RequirementsQuarto command line tool (<https://github.com/quarto-dev/quarto-cli>).
URLhttps://github.com/seandavi/HTAN https://seandavi.github.io/HTAN/
Bug Reportshttps://github.com/seandavi/HTAN/issues
See More
Suggests anndataR, BiocIO, ggplot2, knitr, Matrix, quarto, rhdf5, scales, scater, scrapper, SeuratObject, TENxIO, tidyr, testthat (>= 3.0.0), VisiumIO, withr
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Package Archives

Follow Installation instructions to use this package in your R session.

Source Package HTAN_0.99.1.tar.gz
Windows Binary (x86_64)
macOS Binary (big-sur-x86_64)
macOS Binary (sonoma-arm64)
Source Repositorygit clone https://git.bioconductor.org/packages/HTAN
Source Repository (Developer Access)git clone git@git.bioconductor.org:packages/HTAN
Package Short Url https://bioconductor.org/packages/HTAN/
Package Downloads ReportDownload Stats