HiCBricks

DOI: 10.18129/B9.bioc.HiCBricks    

This package is for version 3.9 of Bioconductor; for the stable, up-to-date release version, see HiCBricks.

Framework for Storing and Accessing Hi-C Data Through HDF Files

Bioconductor version: 3.9

A flexible framework for storing and accessing high-resolution Hi-C data through HDF files. HiCBricks allows import of Hi-C data through various formats such as the 2D matrix format or a generalized n-column table formats. In terms of access, HiCBricks offers functions to retrieve values from genomic loci separated by a certain distance, or the ability to fetch matrix subsets using word alike terms. HiCBricks will at a later point offer the ability to fetch multiple matrix subsets using fewer calls. It offers the capacity to store GenomicRanges that may be associated to a particular Hi-C experiment, to do basic ranges overlap (any, within) with the Hi-C experiment associated Ranges object and also to store any metadata that users may think to be relevant for their Hi-C experiment. Finally, you can do TAD calls with LSD and create pretty heatmaps.

Author: Koustav Pal [aut, cre], Carmen Livi [ctb], Ilario Tagliaferri [ctb]

Maintainer: Koustav Pal <koustav.pal at ifom.eu>

Citation (from within R, enter citation("HiCBricks")):

Installation

To install this package, start R (version "3.6") and enter:

if (!requireNamespace("BiocManager", quietly = TRUE))
    install.packages("BiocManager")

BiocManager::install("HiCBricks")

For older versions of R, please refer to the appropriate Bioconductor release.

Documentation

To view documentation for the version of this package installed in your system, start R and enter:

browseVignettes("HiCBricks")

 

HTML R Script IntroductionToHiCBricks.html
PDF   Reference Manual
Text   NEWS
Text   LICENSE

Details

biocViews DataImport, HiC, Infrastructure, Sequencing, Software, Technology
Version 1.2.0
In Bioconductor since BioC 3.8 (R-3.5) (1 year)
License MIT + file LICENSE
Depends R (>= 3.5), utils, curl, rhdf5, R6, grid
Imports ggplot2, viridis, RColorBrewer, scales, reshape2, stringr, data.table, GenomeInfoDb, GenomicRanges, stats, IRanges, grDevices, S4Vectors, digest
LinkingTo
Suggests BiocStyle, knitr, rmarkdown
SystemRequirements
Enhances
URL
Depends On Me
Imports Me
Suggests Me
Links To Me
Build Report  

Package Archives

Follow Installation instructions to use this package in your R session.

Source Package HiCBricks_1.2.0.tar.gz
Windows Binary HiCBricks_1.2.0.zip (32- & 64-bit)
Mac OS X 10.11 (El Capitan) HiCBricks_1.2.0.tgz
Source Repository git clone https://git.bioconductor.org/packages/HiCBricks
Source Repository (Developer Access) git clone git@git.bioconductor.org:packages/HiCBricks
Package Short Url https://bioconductor.org/packages/HiCBricks/
Package Downloads Report Download Stats

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