DOI: 10.18129/B9.bioc.ORFik    

This package is for version 3.8 of Bioconductor; for the stable, up-to-date release version, see ORFik.

Open Reading Frames in Genomics

Bioconductor version: 3.8

Tools for manipulation of RiboSeq, RNASeq and CageSeq data. ORFik is extremely fast through use of C, data.table and GenomicRanges. Package allows to reassign starts of the transcripts with the use of CageSeq data, automatic shifting of RiboSeq reads, finding of Open Reading Frames for the whole genomes and many more.

Author: Kornel Labun [aut, cre, cph], Haakon Tjeldnes [aut, dtc], Katarzyna Chyzynska [ctb, dtc], Evind Valen [ths, fnd]

Maintainer: Kornel Labun <kornellabun at gmail.com>

Citation (from within R, enter citation("ORFik")):


To install this package, start R (version "3.5") and enter:

if (!requireNamespace("BiocManager", quietly = TRUE))

For older versions of R, please refer to the appropriate Bioconductor release.


To view documentation for the version of this package installed in your system, start R and enter:



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biocViews Alignment, Coverage, DataImport, FunctionalGenomics, ImmunoOncology, RNASeq, RiboSeq, Sequencing, Software
Version 1.2.1
In Bioconductor since BioC 3.7 (R-3.5) (1 year)
License MIT + file LICENSE
Depends R (>= 3.5.0), IRanges(>= 2.13.28), GenomicRanges(>= 1.31.23), GenomicAlignments(>= 1.15.13)
Imports S4Vectors(>= 0.17.39), GenomeInfoDb(>= 1.15.5), GenomicFeatures(>= 1.31.10), rtracklayer(>= 1.39.9), Rcpp (>= 0.12.16), data.table (>= 1.10.4-3), Biostrings(>= 2.47.12), stats, tools, Rsamtools(>= 1.31.3), BiocGenerics(>= 0.25.3)
LinkingTo Rcpp
Suggests testthat, rmarkdown, knitr, BiocStyle, BSgenome, BSgenome.Hsapiens.UCSC.hg19, ggplot2 (>= 2.2.1)
URL https://github.com/JokingHero/ORFik
BugReports https://github.com/JokingHero/ORFik/issues
Depends On Me
Imports Me
Suggests Me
Links To Me
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Follow Installation instructions to use this package in your R session.

Source Package ORFik_1.2.1.tar.gz
Windows Binary ORFik_1.2.1.zip
Mac OS X 10.11 (El Capitan) ORFik_1.2.1.tgz
Source Repository git clone https://git.bioconductor.org/packages/ORFik
Source Repository (Developer Access) git clone git@git.bioconductor.org:packages/ORFik
Package Short Url http://bioconductor.org/packages/ORFik/
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