ebayesControl
is a named list with (optional) components 'method' (one of 'MOM' or 'MLE') and 'model' (one of 'H0' or 'H1')
method MOM uses a method-of-moments estimator, while MLE using the marginal likelihood.
H0 model estimates the precisions using the intercept alone in each gene, while H1 fits the full model specified by formula
ebayes(sca, ebayesControl, Formula, truncate = Inf)
SingleCellAssay
colData(sca)
used when model='H1'
.numeric
of length two, giving the hyperparameters in terms of a variance (v
) and prior observations (df
), inside a structure
, with component hess
, giving the Fisher Information of the hyperparameters.