synergyfinder

DOI: 10.18129/B9.bioc.synergyfinder    

This package is for version 3.7 of Bioconductor; for the stable, up-to-date release version, see synergyfinder.

Calculate and Visualize Synergy Scores for Drug Combinations

Bioconductor version: 3.7

Efficient implementations for all the popular synergy scoring models for drug combinations, including HSA, Loewe, Bliss and ZIP and visualization of the synergy scores as either a two-dimensional or a three-dimensional interaction surface over the dose matrix.

Author: Liye He <liye.he at helsinki.fi>, Jing Tang <jing.tang at helsinki.fi>

Maintainer: Liye He <liye.he at helsinki.fi>

Installation

To install this package, start R and enter:

## try http:// if https:// URLs are not supported
source("https://bioconductor.org/biocLite.R")
biocLite("synergyfinder")

Documentation

To view documentation for the version of this package installed in your system, start R and enter:

browseVignettes("synergyfinder")

 

PDF	R Script	synergyfinder
PDF		Reference Manual
Text		NEWS
Text		LICENSE

Details

biocViews	Software, Statistical Method
Version	1.6.1
In Bioconductor since	BioC 3.4 (R-3.3) (2 years)
License	Mozilla Public License 2.0 + file LICENSE
Depends
Imports	drc (>= 2.5-12), reshape2 (>= 1.4.1), SpatialExtremes (>= 2.0-2), ggplot2 (>= 2.1.0), gridBase (>= 0.4-7), grid (>= 3.2.4), lattice (>= 0.20-33), gplots (>= 3.0.0), nleqslv (>= 3.0), stats (>= 3.3.0), graphics (>= 3.3.0), grDevices (>= 3.3.0)
LinkingTo
Suggests	knitr, rmarkdown
SystemRequirements
Enhances
URL
Depends On Me
Imports Me
Suggests Me
Links To Me
Build Report

Package Archives

Follow Installation instructions to use this package in your R session.

Source Package	synergyfinder_1.6.1.tar.gz
Windows Binary	synergyfinder_1.6.1.zip
Mac OS X 10.11 (El Capitan)	synergyfinder_1.6.1.tgz
Source Repository	git clone https://git.bioconductor.org/packages/synergyfinder
Source Repository (Developer Access)	git clone git@git.bioconductor.org:packages/synergyfinder
Package Short Url	http://bioconductor.org/packages/synergyfinder/
Package Downloads Report	Download Stats