Calculate and Visualize Synergy Scores for Drug Combinations


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Documentation for package ‘synergyfinder’ version 1.2.0

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BaselineCorrectionSD Baseline correction for the dose-response matrix of drug combinations
Bliss Synergy score based on Bliss model
CalculateSynergy Calculate the synergy scores for drug combinations
FittingSingleDrug Fitting single drug dose-response curve
HSA HSA synergy score based on highest single agent (HSA) model
Loewe Delta synergy score based on Loewe model
mathews_screening_data A high-throughput drug combination screening data
PlotDoseResponse Visualize the drug combination dose-response data
PlotSynergy Drug interaction landscape
ReshapeData Transform the response data from the data frame format to dose-response matrixes
ZIP Delta synergy score based on zero interaction potency (ZIP) model