Package: genomicInstability
Version: 1.19.0
Date: 2020-02-21
Title: Genomic Instability estimation for scRNA-Seq
Authors@R: c(person("Mariano", "Alvarez", role=c("aut", "cre"),
           email="reef103@gmail.com"),
           person("Pasquale", "Laise", role="aut",
           email="plaise@darwinhealth.com"),
           person("DarwinHealth", role="cph"))
Depends: R (>= 4.1.0), checkmate
Suggests: SingleCellExperiment, ExperimentHub, pROC
Imports: mixtools, SummarizedExperiment
Description: 
    This package contain functions to run genomic instability analysis (GIA)
    from scRNA-Seq data.
    GIA estimates the association between gene expression and genomic location
    of the coding genes.
    It uses the aREA algorithm to quantify the enrichment of sets of
    contiguous genes (loci-blocks) on the gene expression profiles and
    estimates the Genomic Instability Score (GIS) for each analyzed cell.
License: file LICENSE
biocViews: SystemsBiology, GeneExpression, SingleCell
BiocType: Software
URL: https://github.com/DarwinHealth/genomicInstability
BugReports: https://github.com/DarwinHealth/genomicInstability
Encoding: UTF-8
ARoxygenNote: 7.1.1
RoxygenNote: 7.1.1
git_url: https://git.bioconductor.org/packages/genomicInstability
git_branch: devel
git_last_commit: 190734f
git_last_commit_date: 2026-04-28
Repository: Bioconductor 3.24
Date/Publication: 2026-05-18
NeedsCompilation: no
Packaged: 2026-05-18 22:09:27 UTC; biocbuild
Author: Mariano Alvarez [aut, cre],
  Pasquale Laise [aut],
  DarwinHealth [cph]
Maintainer: Mariano Alvarez <reef103@gmail.com>
Built: R 4.6.0; ; 2026-05-19 04:52:56 UTC; unix
