# Deep characterization of cancer drugs

## Documentation for package ‘DeepTarget’ version 1.5.0

- DESCRIPTION file
- User guides, package vignettes and other documentation
- Package NEWS
- Package README

## Help Pages

computeCor | Compute a correlation between the every gene vs each drug response
Depmap2DeepTarget | Retrieval and preparation of input data required from Depmap to Deeptarget package.
DMB | Predicting Drug Mutant Binding for mutant or non-mutant form
DoInteractExp | Compute the interaction between the drug and KO expression
DoInteractMutant | Compute interaction between the drug and KO expression in term of mutant vs non-mutant
DoPWY | Provide a probability score for each pathway for the primary of mechanism of action (MOA) of a drug
DTR | Predicting Drug Target Response (DTR) for primary or secondary targets
OntargetM | An object containing a small part of the data from the Cancer Dependency Map (depmap.org) to demonstrate in DeepTarget pipeline
plotCor | Plot the correlation
plotSim | Plot the similarty between corelation values and P vals for all genes. The top 5 genes are labeled.
PredMaxSim | Predict the most similar gene to the drug response
PredTarget | Prediction of the most similar known targeted gene.