Geneset	Genes	qvalue
KEGG_VALINE_LEUCINE_AND_ISOLEUCINE_BIOSYNTHESIS	PDHB,VARS2,IARS2,PDHA1,PDHA2,LARS,LARS2,VARS,BCAT1,BCAT2,IARS	0.203046528
KEGG_LYSINE_DEGRADATION	SUV39H2,AASDHPPT,DLST,ALDH1B1,AASDH,ALDH2,ACAT2,PLOD2,PLOD1,TMLHE,EHMT2,ACAT1,SETD8,HADH,SETMAR,OGDH,HADHA,BBOX1,AASS,ECHS1,ALDH9A1,ALDH3A2,SUV420H1,SUV39H1,ASH1L,SETD1B,DOT1L,WHSC1,EHHADH,OGDHL,SETD1A,GCDH,SUV420H2,SETD7,ALDH7A1,WHSC1L1,EHMT1,SETDB1,AADAT,SETD2,SETDB2,PLOD3,NSD1,PIPOX	0.129292888
KEGG_GLYCEROLIPID_METABOLISM	MBOAT2,GPAM,LIPG,DGKZ,DGKE,DGKD,DGKH,MBOAT1,GK,DGAT2,GK2,GLA,ALDH7A1,AGK,DAK,AGPAT3,AWAT2,AGPAT4,AKR1B1,PNLIPRP2,PNLIPRP1,PNLIP,DGAT1,GLYCTK,LPL,ALDH1B1,DGKQ,ALDH2,DGKB,DGKG,AKR1A1,DGKA,PPAP2B,LIPC,DGKI,LCLAT1,AGPAT9,MGLL,AGPAT6,ALDH9A1,ALDH3A2,PNPLA3,PPAP2A,PPAP2C,AGPAT1,AGPAT2,CEL,GPAT2,LIPF	0.014208608
KEGG_GLYCEROPHOSPHOLIPID_METABOLISM	PEMT,PLA2G15,GPD1,GPD1L,LPGAT1,GPAM,MBOAT2,MBOAT7,CHAT,LPCAT1,PTDSS1,ACHE,PLA2G3,DGKZ,ETNK1,DGKE,DGKD,PCYT1A,DGKH,JMJD7-PLA2G4B,CHPT1,MBOAT1,PLA2G6,PLA2G2E,PLA2G10,LPCAT3,PLA2G2A,ETNK2,PLA2G4A,PLA2G5,PLA2G12B,PLA2G4B,PTDSS2,PLA2G2F,PCYT2,CDS1,AGPAT3,AGPAT4,PGS1,LYPLA1,PLA2G1B,C17orf48,CDIPT,DGKQ,CDS2,DGKB,DGKG,PPAP2B,DGKA,DGKI,PHOSPHO1,LCLAT1,TAZ,AGPAT9,GNPAT,LPCAT4,PLA2G4E,AGPAT6,CHKA,PPAP2A,PPAP2C,LYPLA2,PLA2G2C,AGPAT1,PLA2G2D,LPCAT2,PLA2G12A,AGPAT2,PLD1,CHKB,PISD,PLD2,PCYT1B,GPAT2,LCAT,CRLS1,GPD2	0.122186685
KEGG_BIOSYNTHESIS_OF_UNSATURATED_FATTY_ACIDS	ACOT4,TECR,BAAT,ELOVL5,ELOVL6,ACOT2,YOD1,ELOVL2,FADS1,FADS2,ACOX3,PECR,SCD5,SCD,PTPLA,ACAA1,HADHA,ACOT1,ACOT7,ACOX1,HSD17B12,PTPLB	0.155511346
KEGG_ABC_TRANSPORTERS	ABCA7,ABCG4,ABCD1,ABCC12,ABCA1,TAP2,ABCA6,TAP1,ABCA5,ABCB8,ABCA10,ABCD4,ABCA3,ABCB11,ABCD3,ABCA2,ABCC2,ABCC11,ABCC6,ABCC3,ABCC9,ABCG2,ABCC4,ABCC5,ABCA12,ABCG1,ABCB4,CFTR,ABCB1,ABCC1,ABCD2,ABCB6,ABCB7,ABCA8,ABCA4,ABCC8,ABCC10,ABCB10,ABCB9,ABCA13,ABCA9,ABCB5,ABCG5,ABCG8	0.208729214
KEGG_SPLICEOSOME	EFTUD2,LSM5,SF3A1,HNRNPA1L2,SF3B2,PRPF19,SNRNP27,HNRNPA3,LSM6,USP39,DDX42,NCBP1,SF3B1,MAGOH,CDC40,SF3B3,SRSF9,ACIN1,TXNL4A,TCERG1,U2AF2,RBM17,PRPF38B,THOC1,PLRG1,CCDC12,MAGOHB,HSPA8,LSM7,CHERP,NAA38,PQBP1,RBMX,LSM4,EIF4A3,SF3A3,DDX46,RBM25,PRPF40A,THOC3,NHP2L1,PRPF40B,LSM2,SRSF8,SF3A2,SMNDC1,BCAS2,NCBP2,PRPF8,LOC120364,THOC4,DDX39B,CWC15,DDX23,PRPF18,CDC5L,SF3B5,SNRNP40,PRPF31,SNW1,DHX15,WBP11,HNRNPU,CTNNBL1,HNRNPK,TRA2A,SNRNP200,HSPA1L,HSPA1B,RBM22,HSPA2,HSPA1A,ZMAT2,PRPF6,DHX16,U2AF1,PRPF38A,HNRNPC,DDX5,DHX8,HSPA6,DHX38,ISY1,XAB2,SNRPG,SNRPE,SNRPF,SNRPD2,SNRPD3,SART1,SYF2,CRNKL1,U2SURP,HNRNPA1,PRPF3,AQR,PRPF4,LSM3,SF3B4,PPIH,LOC653884,SLU7,BUD31,PHF5A,SRSF10,SRSF6,SNRPA,RBM8A,SRSF7,SNRPA1,HNRNPM,SNRPB,TRA2B,SNRPB2,PUF60,SRSF5,SNRNP70,PCBP1,PPIL1,SF3B14,SRSF4,SRSF3,SNRPD1,THOC2,SNRPC,PPIE,SRSF2,SRSF1	0.125396603
KEGG_PPAR_SIGNALING_PATHWAY	SLC27A5,SLC27A4,SORBS1,ACADL,CYP4A11,ACADM,APOA2,CD36,FADS2,APOA1,CYP7A1,SLC27A1,SCD,CYP8B1,UCP1,DBI,NR1H3,ACSL6,ME1,MMP1,GK,GK2,APOA5,RXRB,RXRG,PLTP,PDPK1,RXRA,ILK,APOC3,ACOX2,ACOX3,CYP27A1,OLR1,CPT2,ACAA1,CPT1B,ANGPTL4,SLC27A2,LPL,FABP1,CPT1A,PCK2,FABP4,CPT1C,FABP2,PCK1,SCP2,PPARA,AQP7,PLIN1,CYP4A22,FABP3,FABP5,FABP6,FABP7,ACSL5,ADIPOQ,SLC27A6,HMGCS2,EHHADH,UBC,PPARG,PPARD,ACSL1,SCD5,ACOX1,ACSL3,ACSL4	0.050519495
KEGG_CELL_CYCLE	CDC16,CDC7,CDC45,GADD45B,DBF4,ANAPC1,CREBBP,MDM2,ABL1,SMC1B,LOC728622,GADD45G,ATM,ATR,ANAPC7,RBL2,ANAPC5,RBL1,MYC,CDC14B,SMC1A,CDC14A,LOC731751,SKP1,TGFB2,TGFB1,GADD45A,STAG1,LOC650621,PLK1,RBX1,STAG2,TGFB3,MCM4,ORC6,CCND1,MAD1L1,MCM3,MCM6,MCM5,YWHAB,CCNA2,MCM7,BUB1,CHEK1,WEE2,MCM2,PTTG1,CDC27,CDC25B,CDC25C,LOC651610,CDC25A,CDC6,CDC20,BUB3,YWHAZ,CCND2,YWHAH,CCNB1,YWHAG,YWHAE,CCNE1,ORC3,CCND3,PTTG2,SFN,E2F1,TFDP1,ZBTB17,CDK1,ESPL1,ANAPC10,RAD21,BUB1B,ANAPC11,RB1,SKP2,CUL1,SMAD3,SMAD4,ANAPC2,TFDP2,PRKDC,MAD2L1,ANAPC4,SMAD2,YWHAQ,CHEK2,CDC23,EP300,GSK3B,CDKN2A,CDKN1C,CDKN1B,CDKN1A,CDKN2D,CCNA1,CDKN2B,CDKN2C,FZR1,SMC3,ANAPC13,PCNA,TTK,PKMYT1,CDK2,CDC26,E2F5,CDK4,WEE1,E2F4,E2F3,TP53,E2F2,ORC1,ORC2,CCNE2,CDK6,ORC4,CCNB2,CDK7,MAD2L2,ORC5,HDAC1,HDAC2,CCNH,CCNB3	0.123307451
KEGG_UBIQUITIN_MEDIATED_PROTEOLYSIS	CDC16,KLHL13,PIAS3,UBA6,UBE2L6,BIRC3,HERC1,XIAP,PML,HERC2,PRPF19,ANAPC1,UBE2S,UBE2O,UBE2M,UBE2Q2,MAP3K1,UBE4A,BRCA1,MDM2,UBE2K,UBE2D4,UBOX5,KLHL9,UBR5,UBE3A,UBE2R2,RFWD2,TRIM37,FBXW8,UBE2E3,LOC652671,LOC728622,ANAPC7,ANAPC5,UBE2QL1,PIAS1,SMURF1,STUB1,UBE2G2,BTRC,UBE2G1,UBE2I,SOCS1,UBE2H,UBE2J2,SKP1,TRAF6,FBXW11,UBE2L3,NHLRC1,UBE2N,UBE4B,MGRN1,LOC650621,RBX1,DDB2,NEDD4L,SOCS3,SIAH1,DDB1,DET1,RNF7,BIRC2,UBE2U,UBE2Z,UBA7,VHL,UBA1,UBE2NL,PIAS4,AIRE,FBXO4,CBLC,UBE2A,CDC27,HUWE1,UBE2B,CDC34,UBE2D1,UBA3,UBE2E1,UBE2E2,UBE2D2,CDC20,UBE2D3,ITCH,UBE2Q1,ANAPC10,RCHY1,UBE2W,WWP1,PPIL2,TCEB1,UBE3C,UBE2J1,ANAPC11,TCEB2,SAE1,UBA2,RHOBTB2,CUL5,KEAP1,SYVN1,PARK2,SKP2,PIAS2,CUL7,CUL1,FBXW7,CUL2,CUL3,UBE3B,CUL4A,CUL4B,ANAPC2,FANCL,ANAPC4,SMURF2,CDC23,CBLB,CBL,LOC652346,NEDD4,TRIM32,FZR1,TRIP12,UBE2F,ANAPC13,FBXO2,HERC4,WWP2,UBE2C,CDC26,HERC3,BIRC6,ERCC8,MID1	0.106038315
KEGG_ENDOCYTOSIS	F2R,EPN3,IQSEC1,IQSEC3,ADRBK2,ADRBK1,ADRB3,ADRB2,EPN2,STAMBP,ADRB1,IGF1R,CLTCL1,HGS,VPS37C,FAM125B,PIP4K2B,RUFY1,SMAP2,HLA-G,FLT1,STAM,MDM2,PIKFYVE,VPS37D,PIP5K1A,VPS28,CHMP2B,FAM125A,PIP5K1B,RAB11FIP1,ACAP1,ARRB2,AP2A2,GRK7,ARRB1,AP2B1,AP2A1,EEA1,GRK1,CSF1R,SMURF1,LOC652799,SH3GLB1,VPS4A,ARFGAP3,DNM2,HSPA8,VPS36,PARD6B,RAB31,RAB11A,TRAF6,CHMP4A,PDCD6IP,LDLR,PIP5K1C,NEDD4L,ACAP3,CHMP5,ARAP2,IQSEC2,HLA-F,MET,HLA-E,ARAP3,ASAP2,RAB11B,RAB11FIP5,ZFYVE20,PDGFRA,AGAP1,DNM3,AGAP2,ARFGAP1,ARAP1,CHMP4B,CBLC,ACAP2,VPS25,RAB22A,EHD1,PLD1,PLD2,ITCH,CDC42,SH3GLB2,PARD6A,CHMP6,VTA1,RNF41,DNAJC6,ARF6,CHMP1B,PSD2,USP8,PSD4,WWP1,HLA-C,CXCR4,HLA-B,PRKCI,CXCR2,SH3GL3,CXCR1,TSG101,HLA-A,ERBB4,HSPA1L,HSPA1B,ERBB3,HSPA2,RAB11FIP4,SH3GL1,EPS15,DNM1L,HSPA1A,TFRC,SH3GL2,SMAP1,RAB11FIP2,FGFR2,KDR,KIT,FGFR4,GIT2,DNM1,FGFR3,LDLRAP1,RET,CCR5,PRKCZ,PSD3,ASAP3,HSPA6,RAB5C,DAB2,SMURF2,HRAS,CHMP3,VPS37A,EGFR,IL2RG,VPS37B,IL2RB,CBLB,CBL,PSD,NEDD4,EGF,PARD6G,SH3KBP1,LOC652614,ARFGAP2,RAB5B,RAB4A,EHD4,RAB5A,AP2S1,EHD2,IL2RA,EHD3,AP2M1,SNF8,SRC,VPS4B,STAM2,CHMP2A,GIT1,GRK6,RABEP1,VPS45,RAB11FIP3,CLTA,CLTB,CLTC,CHMP4C,GRK4,PARD3,GRK5,ASAP1,NTRK1,EPN1	0.122186685
KEGG_WNT_SIGNALING_PATHWAY	JUN,LRP5,LRP6,PPP3R2,SFRP2,SFRP1,PPP3CC,VANGL1,PPP3R1,FZD1,FZD4,APC2,FZD6,FZD7,SENP2,FZD8,LEF1,CREBBP,FZD9,PRICKLE1,CTBP2,ROCK1,CTBP1,WNT9B,WNT9A,CTNNBIP1,DAAM2,TBL1XR1,MMP7,CER1,MAP3K7,VANGL2,WNT2B,WNT11,WNT10B,DKK2,LOC728622,CHP2,AXIN1,AXIN2,DKK4,NFAT5,MYC,SOX17,CSNK2A1,CSNK2A2,NFATC4,CSNK1A1,NFATC3,CSNK1E,BTRC,PRKX,SKP1,FBXW11,RBX1,CSNK2B,SIAH1,TBL1Y,WNT5B,CCND1,CAMK2A,NLK,CAMK2B,CAMK2D,CAMK2G,PRKACA,APC,PRKACB,PRKACG,WNT16,DAAM1,CHD8,FRAT1,CACYBP,CCND2,NFATC2,NFATC1,CCND3,PLCB2,PLCB1,CSNK1A1L,PRKCB,PLCB3,PRKCA,PLCB4,WIF1,PRICKLE2,PORCN,RHOA,FRAT2,PRKCG,MAPK9,MAPK10,WNT3A,DVL3,RAC2,DVL2,RAC3,FZD3,DKK1,CXXC4,DVL1,FOSL1,CUL1,WNT10A,WNT4,SMAD3,TCF7,SMAD4,RAC1,TCF7L2,SMAD2,WNT1,MAPK8,EP300,WNT7A,GSK3B,WNT7B,PSEN1,WNT8A,WNT8B,WNT2,WNT3,WNT5A,WNT6,CTNNB1,PPP2CB,PPP2CA,PPP2R1A,TBL1X,PPP2R1B,ROCK2,NKD1,FZD10,FZD5,NKD2,TCF7L1,RUVBL1,PPARD,PPP3CB,TP53,PPP3CA,PPP2R5A,PPP2R5E,PPP2R5D,PPP2R5C,PPP2R5B,FZD2,SFRP5,SFRP4,CHP	0.128403716
KEGG_DORSO_VENTRAL_AXIS_FORMATION	SOS2,NOTCH4,NOTCH3,NOTCH2,EGFR,NOTCH1,KRAS,FMN2,LOC652554,ETV7,PIWIL3,ETV6,PIWIL2,MAP2K1,PIWIL1,GRB2,SPIRE2,CPEB1,MAPK3,ETS1,ETS2,SPIRE1,SOS1,PIWIL4,MAPK1	0.233097504
KEGG_NOTCH_SIGNALING_PATHWAY	HES5,DTX3,NOTCH4,DTX3L,NOTCH3,NOTCH2,EP300,HES1,NOTCH1,NUMB,PSEN2,PSEN1,PTCRA,SNW1,APH1A,KAT2A,ADAM17,RFNG,RBPJ,DTX1,CREBBP,DTX2,MAML1,CTBP2,NCOR2,CTBP1,DVL3,JAG2,DVL2,NUMBL,MAML2,KAT2B,DLL4,PSENEN,DLL3,DVL1,CIR1,DLL1,LFNG,JAG1,MAML3,HDAC1,HDAC2,NCSTN,DTX4,MFNG,RBPJL	0.129292888
KEGG_ADHERENS_JUNCTION	MLLT4,LOC100418883,SORBS1,WAS,SNAI2,IGF1R,RHOA,CREBBP,LEF1,ACTN4,PTPN6,ACTN1,SNAI1,ERBB2,WASF2,RAC2,PTPRJ,WASL,LOC646821,RAC3,PTPRF,WASF1,MAP3K7,FGFR1,IQGAP1,SMAD3,MAPK3,TCF7,SMAD4,ACTG1,INSR,WASF3,CTNNA1,PTPRB,RAC1,TCF7L2,SMAD2,MAPK1,CSNK2A1,PVRL3,CSNK2A2,EP300,EGFR,VCL,CTNNA2,CTNNB1,CTNND1,FARP2,CSNK2B,TGFBR2,PTPRM,PVRL4,TGFBR1,ACTB,TJP1,MET,SSX2IP,SRC,NLK,TCF7L1,YES1,FER,BAIAP2,CTNNA3,LMO7,FYN,ACP1,PTPN1,PARD3,CDC42,ACTN2,PVRL2,CDH1,ACTN3,PVRL1	0.107859121
KEGG_CYTOSOLIC_DNA_SENSING_PATHWAY	CXCL10,CHUK,IFNA5,IFNA4,IFNA2,POLR1D,CCL5,CCL4,IFNA1,RIPK1,POLR3K,AIM2,IKBKB,IFNA17,CASP1,IFNA21,IFNA6,POLR3H,IFNA7,IFNA8,IFNA10,IFNA13,IFNA14,IFNA16,POLR3C,IKBKE,POLR3G,POLR3B,POLR3F,NFKB1,NFKBIB,NFKBIA,IRF3,IKBKG,TREX1,POLR1C,IL18,RELA,ZBP1,POLR3D,RIPK3,IFNB1,IL33,PYCARD,POLR3GL,IL1B,ADAR,DDX58,MAVS,CCL4L1,TBK1,TMEM173,CCL4L2,POLR3A,IL6,IRF7	0.249324287
KEGG_MELANOGENESIS	CALM2,CALM1,TYR,CREB3L1,FZD1,FZD4,FZD6,FZD7,LEF1,CREBBP,CREB3,FZD8,FZD9,POMC,WNT9B,WNT9A,CREB1,WNT2B,WNT11,EDN1,WNT10B,NRAS,EDNRB,LOC652799,KRAS,PRKX,GNAI1,GNAI2,CALML5,ADCY3,ADCY2,ADCY1,CREB3L3,WNT5B,CAMK2A,CAMK2B,CAMK2D,CAMK2G,PRKACA,GNAQ,PRKACB,PRKACG,GNAS,GNAI3,WNT16,GNAO1,CALML3,DCT,CALM3,PLCB2,ADCY8,ADCY9,PLCB1,ADCY6,ADCY7,PRKCB,RAF1,PLCB3,PRKCA,PLCB4,ADCY5,CREB3L4,ASIP,KITLG,PRKCG,MC1R,WNT3A,DVL3,DVL2,MAP2K2,MAP2K1,KIT,FZD3,DVL1,ADCY4,TYRP1,WNT4,WNT10A,MAPK3,TCF7,MAPK1,TCF7L2,HRAS,WNT1,EP300,GSK3B,WNT7A,WNT7B,WNT8A,WNT8B,WNT2,WNT3,WNT5A,CTNNB1,WNT6,FZD10,CREB3L2,FZD5,TCF7L1,MITF,FZD2,CALML6	0.053581282
KEGG_ADIPOCYTOKINE_SIGNALING_PATHWAY	STAT3,CHUK,PTPN11,PPARGC1A,NPY,TNF,SLC2A4,CD36,SLC2A1,MTOR,ADIPOR2,PRKAG2,ACSL6,POMC,MAPK9,MAPK10,PRKCQ,RXRB,RXRG,IKBKB,PRKAG3,RXRA,TNFRSF1B,ADIPOR1,AKT1,AKT2,TNFRSF1A,JAK2,LEPR,AKT3,CPT1B,LEP,ACACB,NFKB1,NFKBIB,NFKBIA,NFKBIE,IKBKG,MAPK8,CPT1A,PCK2,CPT1C,PCK1,RELA,STK11,PPARA,TRAF2,PRKAB2,PRKAB1,PRKAA2,PRKAA1,SOCS3,TRADD,ACSL5,ADIPOQ,G6PC2,IRS2,ACSL1,AGRP,PRKAG1,G6PC,IRS1,CAMKK1,CAMKK2,IRS4,ACSL3,ACSL4	0.036205638
KEGG_TYPE_II_DIABETES_MELLITUS	PIK3R5,GCK,MAPK8,TNF,MAFA,SOCS1,SLC2A4,SLC2A2,MTOR,SOCS2,SOCS3,INS,PRKCD,PRKCE,MAPK9,HK2,CACNA1A,MAPK10,HK3,HK1,PIK3R3,CACNA1D,CACNA1E,CACNA1B,PDX1,CACNA1C,ADIPOQ,IKBKB,IRS2,ABCC8,SOCS4,PIK3CA,CACNA1G,PIK3CB,PIK3CD,PRKCZ,KCNJ11,MAPK3,IRS1,PKLR,INSR,PKM2,PIK3CG,IRS4,PIK3R1,PIK3R2,MAPK1	0.072807507
KEGG_MATURITY_ONSET_DIABETES_OF_THE_YOUNG	MNX1,NEUROG3,GCK,HHEX,HES1,MAFA,PAX6,SLC2A2,BHLHA15,HNF1B,HNF4G,NKX6-1,HNF1A,FOXA3,HNF4A,NKX2-2,ONECUT1,NEUROD1,INS,FOXA2,PAX4,PDX1,IAPP,NR5A2,PKLR	0.008209418
KEGG_ALZHEIMERS_DISEASE	UQCR10,NAE1,CALM2,NDUFA5,NDUFA4,COX6CP3,CALM1,ATP2A1,PPP3R2,EIF2AK3,PPP3CC,ATP2A3,PPP3R1,ATP2A2,NDUFS7,CYTB,ADAM17,BACE2,ATP5O,COX2,COX1,COX8C,MME,COX3,COX5B,ITPR3,PSENEN,LRP1,COX4I1,APOE,ATP6,ATP8,CHP2,ATP5H,NDUFA2,NDUFA3,NDUFA1,CAPN2,LPL,CAPN1,LOC100133737,APAF1,ATP5G1P5,HSD17B10,APH1A,UQCRQ,ATP5D,CALML5,GAPDH,ATF6,COX7A2L,IDE,ATP5G3,ATP5G2,ADAM10,ATP5G1,ATP5F1,ATP5E,COX5A,CDK5R1,ERN1,GNAQ,UQCRHL,ATP5A1,BACE1,CALML3,APBB1,ATP5J,CYCS,SDHA,CALM3,NDUFA4L2,NCSTN,CASP9,PLCB2,COX8A,CASP8,COX7C,CASP7,PLCB1,PLCB3,PLCB4,TNF,LOC642502,RYR3,FADD,SDHD,SDHB,SDHC,COX7B,BAD,COX7A1,COX7A2,COX6C,ATP5B,GRIN1,GRIN2A,GRIN2B,COX6B1,CACNA1D,BID,ATP5C1,GRIN2C,GRIN2D,LOC644310,CACNA1C,NOS1,CACNA1F,CACNA1S,COX7B2,CASP3,TNFRSF1A,UQCRB,COX6A2,MAPK3,COX6A1,UQCRH,UQCRFS1,UQCRC2,UQCRC1,MAPK1,NDUFB3,NDUFB1,NDUFB2,ITPR1,NDUFA10,ITPR2,NDUFAB1,PSEN2,GSK3B,PSEN1,NDUFA9,NDUFA7,NDUFA8,UQCR11,NDUFA6,NDUFV3,LOC727947,COX6B2,COX4I2,IL1B,SNCA,MAPT,NDUFB10,NDUFS8,NDUFC1,NDUFC2,NDUFS1,NDUFV2,NDUFB6,NDUFS4,NDUFB7,NDUFV1,NDUFB8,NDUFS6,NDUFB9,NDUFS5,NDUFS2,PPP3CB,NDUFB4,NDUFS3,PPP3CA,APP,NDUFB5,CDK5,FAS,CYC1,CHP,CALML6	0.189366622
KEGG_HUNTINGTONS_DISEASE	POLR2G,POLR2H,POLR2E,UQCR10,POLR2F,NDUFA5,PPARGC1A,NDUFA4,POLR2I,COX6CP3,POLR2J,TAF4,NRF1,DCTN2,CREB3L1,NDUFS7,CYTB,CREBBP,CREB3,POLR2K,ATP5O,COX2,COX1,UCP1,CLTCL1,COX8C,DNALI1,POLR2L,COX3,LOC729317,COX5B,COX4I1,CREB1,HIP1,AP2A2,ATP6,AP2B1,DCTN4,ATP8,TAF4B,ATP5H,AP2A1,NDUFA2,NDUFA3,NDUFA1,DNAI1,LOC100133737,APAF1,ATP5G1P5,VDAC1,VDAC2,VDAC3,UQCRQ,ATP5D,DNAH1,BBC3,BDNF,COX7A2L,ATP5G3,ATP5G2,CREB3L3,ATP5G1,ATP5F1,ATP5E,COX5A,GNAQ,DNAH2,SLC25A6,SP1,UQCRHL,ATP5A1,SLC25A5,SLC25A4,ATP5J,RCOR1,CYCS,TGM2,SDHA,DCTN1,POLR2B,DNAL1,POLR2A,NDUFA4L2,POLR2D,POLR2C,DNAL4,SLC25A31,CASP9,PLCB2,COX8A,GRM5,CASP8,COX7C,PLCB1,PLCB3,PLCB4,DNAI2,LOC642502,IFT57,CREB3L4,PPID,SDHD,SDHB,SDHC,TFAM,HAP1,COX7B,COX7A1,COX7A2,COX6C,POLR2J2,ATP5B,GRIN1,SOD1,GRIN2B,COX6B1,SOD2,ATP5C1,LOC644310,BAX,COX7B2,CASP3,REST,UQCRB,POLR2J3,COX6A2,CREB5,COX6A1,UQCRH,UQCRFS1,UQCRC2,UQCRC1,SIN3A,NDUFB3,NDUFB1,DLG4,TBPL2,NDUFB2,EP300,ITPR1,NDUFA10,NDUFAB1,NDUFA9,NDUFA7,NDUFA8,DNAH3,UQCR11,NDUFA6,NDUFV3,LOC727947,COX6B2,COX4I2,GPX1,TBP,AP2S1,AP2M1,CREB3L2,NDUFS8,NDUFB10,NDUFC1,NDUFC2,NDUFV2,NDUFS1,NDUFS4,NDUFB6,NDUFV1,NDUFB7,NDUFS6,NDUFB8,NDUFS5,NDUFB9,PPARG,NDUFS2,TP53,NDUFB4,NDUFS3,NDUFB5,CYC1,CLTA,CLTB,CLTC,HDAC1,HDAC2,TBPL1,HTT	0.206947328
KEGG_VIBRIO_CHOLERAE_INFECTION	LOC100418883,ATP6V1G1,PDIA4,ADCY9,PRKCB,SLC12A2,SEC61B,PRKCA,TJP2,KDELR3,ATP6V0A1,ATP6V1G2,KDELR2,ATP6V0B,ATP6V1G3,ATP6AP1,PRKCG,CFTR,LOC646821,ATP6V1F,ERO1L,ATP6V0A4,ATP6V0A2,ATP6V0D1,KCNQ1,ARF1,ACTG1,ATP6V0E2,SEC61G,ATP6V1H,PRKX,ATP6V1E2,MUC2,KDELR1,ADCY3,ATP6V0D2,ATP6V0E1,ATP6V1C2,ACTB,TJP1,TCIRG1,PRKACA,PRKACB,PRKACG,GNAS,ATP6V1D,SEC61A2,ATP6V1A,PLCG1,PLCG2,ATP6V1E1,ATP6V1B2,ATP6V1B1,SEC61A1,ATP6V1C1,ATP6V0C	0.249881724
KEGG_COLORECTAL_CANCER	JUN,CASP9,RAF1,BIRC5,APC2,RHOA,LEF1,MSH6,BAD,MAPK9,MAPK10,RAC2,RAC3,BRAF,MLH1,MAP2K1,BAX,AKT1,CASP3,AKT2,AKT3,AXIN1,AXIN2,SMAD3,MAPK3,SMAD4,TCF7,RAC1,MYC,TCF7L2,SMAD2,MAPK1,PIK3R5,MAPK8,APPL1,GSK3B,KRAS,CTNNB1,TGFB2,TGFB1,ARAF,TGFBR2,TGFBR1,TGFB3,CCND1,PIK3R3,BCL2,TCF7L1,MSH2,APC,RALGDS,TP53,MSH3,PIK3CA,PIK3CB,CYCS,PIK3CD,FOS,PIK3CG,DCC,PIK3R1,PIK3R2	0.079263345
KEGG_PANCREATIC_CANCER	CASP9,E2F1,STAT3,CHUK,RAF1,ARHGEF6,STAT1,RAD51,BAD,PGF,MAPK9,MAPK10,ERBB2,RAC2,BRCA2,TGFA,BRAF,RAC3,MAP2K1,IKBKB,RB1,JAK1,AKT1,AKT2,AKT3,SMAD3,MAPK3,SMAD4,NFKB1,RAC1,SMAD2,MAPK1,PIK3R5,IKBKG,MAPK8,EGFR,RELA,KRAS,CDKN2A,EGF,TGFB2,TGFB1,VEGFA,ARAF,VEGFC,VEGFB,TGFBR2,TGFBR1,TGFB3,CCND1,PIK3R3,RALB,BCL2L1,RALA,CDK4,FIGF,RALBP1,RALGDS,TP53,E2F3,E2F2,PIK3CA,PIK3CB,CDK6,PIK3CD,PLD1,PIK3CG,PIK3R1,CDC42,PIK3R2	0.122186685
KEGG_ENDOMETRIAL_CANCER	CASP9,SOS2,RAF1,ELK1,APC2,LEF1,BAD,ERBB2,MAP2K2,BRAF,MLH1,MAP2K1,PDPK1,ILK,AKT1,AKT2,NRAS,AKT3,GRB2,AXIN1,AXIN2,MAPK3,TCF7,CTNNA1,MYC,SOS1,MAPK1,TCF7L2,PIK3R5,HRAS,EGFR,GSK3B,KRAS,CTNNA2,EGF,CTNNB1,ARAF,CCND1,PTEN,PIK3R3,TCF7L1,FOXO3,APC,TP53,PIK3CA,PIK3CB,PIK3CD,CTNNA3,PIK3CG,PIK3R1,PIK3R2,CDH1	0.066019794
KEGG_PROSTATE_CANCER	CASP9,SOS2,E2F1,CHUK,RAF1,IGF1,CREB3L4,MTOR,CREB3L1,PDGFD,NKX3-1,IGF1R,GSTP1,CREB3,CREBBP,LEF1,BAD,INS,PDGFRB,ERBB2,MAP2K2,TGFA,BRAF,MAP2K1,FGFR2,PDPK1,IKBKB,MDM2,RB1,CREB1,AKT1,AKT2,FGFR1,AKT3,NRAS,GRB2,CREB5,MAPK3,TCF7,NFKB1,INSRR,NFKBIA,SOS1,TCF7L2,MAPK1,PIK3R5,IKBKG,HRAS,EP300,EGFR,RELA,PDGFC,GSK3B,KRAS,CDKN1B,EGF,CDKN1A,CTNNB1,HSP90AA1,ARAF,AR,CREB3L3,HSP90B1,SRD5A2,CREB3L2,CCND1,PTEN,PIK3R3,BCL2,PDGFA,PDGFB,TCF7L1,FOXO1,PDGFRA,CDK2,HSP90AB1,TP53,E2F3,E2F2,PIK3CA,PIK3CB,CCNE2,PIK3CD,KLK3,ATF4,PIK3CG,CCNE1,PIK3R1,PIK3R2	0.014033193
KEGG_THYROID_CANCER	PAX8,HRAS,CCDC6,TFG,NCOA4,KRAS,CTNNB1,LEF1,CCND1,MAP2K2,TCF7L1,BRAF,MAP2K1,RXRB,RXRG,RXRA,PPARG,TP53,RET,NRAS,TPR,MAPK3,TCF7,NTRK1,MYC,TPM3,CDH1,MAPK1,TCF7L2	0.005412803
KEGG_BASAL_CELL_CARCINOMA	HHIP,FZD1,APC2,FZD4,FZD6,PTCH2,FZD7,FZD8,LEF1,FZD9,WNT3A,DVL3,WNT9B,DVL2,WNT9A,FZD3,DVL1,WNT2B,WNT11,WNT10B,SMO,AXIN1,WNT4,WNT10A,AXIN2,TCF7,TCF7L2,SHH,WNT1,GSK3B,WNT7A,WNT7B,WNT8A,WNT8B,WNT2,WNT3,WNT5A,CTNNB1,WNT6,STK36,FZD10,WNT5B,FZD5,GLI1,TCF7L1,BMP4,SUFU,APC,BMP2,GLI2,PTCH1,GLI3,WNT16,TP53,FZD2	0.072686212
KEGG_CHRONIC_MYELOID_LEUKEMIA	SOS2,E2F1,CHUK,PTPN11,RAF1,SHC1,BAD,CTBP2,CTBP1,MAP2K2,BRAF,MECOM,MAP2K1,IKBKB,MDM2,RB1,ABL1,AKT1,AKT2,SHC4,AKT3,NRAS,GRB2,STAT5B,SMAD3,MAPK3,STAT5A,SMAD4,NFKB1,NFKBIA,SOS1,MYC,MAPK1,RUNX1,PIK3R5,IKBKG,HRAS,RELA,GAB2,CBLB,CDKN2A,KRAS,CBL,SHC3,CDKN1B,CDKN1A,TGFB2,TGFB1,ARAF,TGFBR2,TGFBR1,TGFB3,CCND1,PIK3R3,BCL2L1,CDK4,CBLC,TP53,E2F3,E2F2,CRK,PIK3CA,PIK3CB,CDK6,CRKL,PIK3CD,SHC2,HDAC1,BCR,HDAC2,PIK3CG,PIK3R1,PIK3R2	0.123107317
KEGG_ACUTE_MYELOID_LEUKEMIA	SOS2,CHUK,STAT3,ZBTB16,RAF1,RARA,PML,JUP,MTOR,CEBPA,LEF1,EIF4EBP1,BAD,PIM2,MAP2K2,BRAF,MAP2K1,KIT,FLT3,SPI1,IKBKB,AKT1,AKT2,RPS6KB1,NRAS,AKT3,RPS6KB2,LOC652671,GRB2,STAT5B,MAPK3,TCF7,STAT5A,NFKB1,MYC,SOS1,TCF7L2,MAPK1,RUNX1,PIK3R5,IKBKG,HRAS,LOC652799,RUNX1T1,RELA,KRAS,LOC652346,CCNA1,ARAF,CCND1,PIK3R3,TCF7L1,PPARD,PIK3CA,PIK3CB,PIM1,PIK3CD,PIK3CG,PIK3R1,PIK3R2	0.014033193
KEGG_SMALL_CELL_LUNG_CANCER	CASP9,MAX,E2F1,CHUK,LAMA1,RARB,PIAS3,FN1,BIRC3,XIAP,ITGA3,ITGA2B,COL4A6,PTK2,COL4A1,COL4A2,PTGS2,NOS2,COL4A4,RXRB,RXRG,IKBKB,RXRA,RB1,SKP2,AKT1,AKT2,PIAS2,ITGAV,LAMC2,ITGB1,AKT3,LAMB2,LAMB3,LAMC1,LAMA4,LAMA5,LAMB1,NFKB1,NFKBIA,MYC,PIK3R5,PIAS1,IKBKG,LAMB4,RELA,APAF1,CDKN1B,LAMA3,LAMA2,TRAF6,TRAF5,TRAF3,CDKN2B,TRAF2,FHIT,TRAF1,ITGA6,CCND1,PTEN,ITGA2,TRAF4,PIK3R3,BCL2,BCL2L1,BIRC2,CDK2,PIAS4,CDK4,LAMC3,TP53,E2F3,E2F2,PIK3CA,PIK3CB,CCNE2,CYCS,CDK6,PIK3CD,PIK3CG,CCNE1,PIK3R1,CKS1B,PIK3R2	0.009715287
KEGG_ARRHYTHMOGENIC_RIGHT_VENTRICULAR_CARDIOMYOPATHY_ARVC	CACNA2D1,CACNB1,LOC100418883,CACNB2,CACNB3,CACNB4,CACNG1,ITGA9,CACNG8,RYR2,JUP,LMNA,CACNG6,ATP2A2,CACNG7,ITGA4,ITGA3,ITGA2B,ITGA7,LEF1,ITGA5,EMD,ACTN4,ITGA11,DSC2,DSG2,ACTN1,DMD,CACNA2D3,CACNA1D,SLC8A1,LOC646821,CACNA1C,CACNA1F,ITGB3,CACNA2D2,CACNA1S,ITGB4,ITGB5,ITGB6,ITGB7,ITGAV,ITGB1,TCF7,ACTG1,CACNA2D4,PKP2,CTNNA1,CDH2,TCF7L2,ITGA10,SGCD,SGCG,SGCA,ITGA8,SGCB,CACNG2,CTNNA2,DAG1,CACNG3,CTNNB1,LAMA2,GJA1,ITGB8,ACTB,ITGA6,ITGA2,ITGA1,CACNG5,CACNG4,TCF7L1,DSP,DES,CTNNA3,ACTN2,ACTN3	0.167592154
KEGG_VIRAL_MYOCARDITIS	CASP9,LOC100418883,CASP8,HLA-DOA,HLA-DOB,CD80,CD86,CD28,EIF4G3,ITGAL,ICAM1,CXADR,MYH13,HLA-C,HLA-B,MYH14,HLA-DMB,HLA-DMA,MYH1,HLA-A,DMD,MYH15,RAC2,LOC646821,BID,HLA-G,RAC3,ABL1,ABL2,CASP3,EIF4G2,PRF1,EIF4G1,ITGB2,ACTG1,RAC1,SGCD,HLA-DRB4,SGCG,HLA-DRB5,SGCA,SGCB,HLA-DRB3,DAG1,CD55,LAMA2,LOC652614,ACTB,HLA-F,HLA-E,CD40LG,CCND1,HLA-DPA1,CD40,HLA-DPB1,MYH7B,HLA-DQA1,HLA-DQA2,HLA-DQB1,CAV1,MYH3,MYH2,CYCS,MYH4,MYH7,MYH6,MYH9,MYH8,MYH11,FYN,MYH10,HLA-DRB1,HLA-DRA	0.197606533
BIOCARTA_RELA_PATHWAY	IKBKG,CHUK,EP300,RELA,TNF,IKBKB,TNFRSF1B,HDAC3,TNFRSF1A,TRAF6,FADD,CREBBP,RIPK1,NFKB1,NFKBIA,TRADD	0.099699458
BIOCARTA_AKT_PATHWAY	CASP9,IKBKG,FOXO4,CHUK,FOXO1,FOXO3,RELA,PDPK1,GHR,IKBKB,AKT1,PIK3CA,GH1,PPP2CA,FASLG,HSP90AA1,YWHAH,BAD,NFKB1,PIK3CG,PIK3R1,NFKBIA	0.123307451
BIOCARTA_ALK_PATHWAY	MEF2C,WNT1,NPPB,NPPA,NOG,GSK3B,GATA4,CTNNB1,TGFB2,CHRD,HNF1A,MYL2,TGFB1,FZD1,ATF2,SMAD5,TGFBR3,TGFBR2,TGFBR1,NKX2-5,TGFB3,SMAD6,BMPR2,BMPR1A,ACVR1,RFC1,BMP4,APC,BMP2,MAP3K7,BMP7,DVL1,BMP5,BMP10,AXIN1,SMAD4,SMAD1	0.129292888
BIOCARTA_CD40_PATHWAY	CD40LG,CD40,IKBKG,CHUK,IKBKAP,MAP3K1,RELA,IKBKB,DUSP1,TRAF6,TRAF3,TNFAIP3,MAP3K14,NFKB1,NFKBIA	0.059144774
BIOCARTA_CERAMIDE_PATHWAY	CASP8,NSMAF,BCL2,MAPK8,RAF1,MAP3K1,RELA,BAX,MAP2K1,TNFRSF1A,MAP2K4,SMPD1,CYCS,TRAF2,FADD,RIPK1,MAPK3,BAD,NFKB1,TRADD,AIFM1,MAPK1	0.178665458
BIOCARTA_COMP_PATHWAY	MASP1,C9,C2,C1S,C6,C3,C5,C1QB,CFD,C1QA,C1R,C1QC,MBL2,C4B,C4A,MASP2,C8A,C7,CFB	0.128659461
BIOCARTA_CXCR4_PATHWAY	HRAS,PTK2,RAF1,PRKCB,PRKCA,RELA,MAP2K1,BCAR1,GNAQ,CRK,GNAI1,PIK3CA,CXCL12,GNGT1,GNB1,PLCG1,MAPK3,CXCR4,PTK2B,PIK3C2G,NFKB1,PIK3R1,PXN,MAPK1	0.171783946
BIOCARTA_CELLCYCLE_PATHWAY	CCND1,E2F1,TFDP1,CDK2,CDKN2A,CDK4,RB1,CDKN1B,CDKN1A,CDK1,CDKN2D,CCNA1,CDKN2B,CDK6,CDKN2C,CDK7,CDC25A,RBL1,CCND2,CCNB1,CCNE1,CCNH,CCND3	0.013419241
BIOCARTA_RNA_PATHWAY	CHUK,RELA,MAP3K14,EIF2S2,EIF2S1,NFKB1,DNAJC3,NFKBIA,EIF2AK2,TP53	0.02447038
BIOCARTA_GH_PATHWAY	SRF,HRAS,RAF1,PRKCB,PRKCA,SHC1,SLC2A4,SOCS1,HNF1A,INS,PTPN6,MAP2K1,GHR,JAK2,PIK3CA,GH1,PLCG1,GRB2,MAPK3,IRS1,STAT5B,STAT5A,INSR,PIK3CG,PIK3R1,SOS1,MAPK1,RPS6KA1	0.129292888
BIOCARTA_IL5_PATHWAY	CCR3,CD4,CCL11,IL4,IL1B,IL5,IL5RA,IL6,HLA-DRB1,HLA-DRA	0.197606533
BIOCARTA_DEATH_PATHWAY	CASP10,CASP9,GAS2,CASP8,CASP7,CHUK,RELA,APAF1,TNFSF12,TNFSF10,BIRC3,XIAP,LMNA,SPTAN1,TNFRSF10A,TRAF2,FADD,CFLAR,TNFRSF10B,RIPK1,MAP3K14,TRADD,TNFRSF25,BCL2,BID,BIRC2,CASP6,CASP3,CYCS,DFFA,DFFB,NFKB1,NFKBIA	0.223056414
BIOCARTA_RACCYCD_PATHWAY	IKBKG,HRAS,E2F1,CHUK,RAF1,TFDP1,RELA,CDKN1B,CDKN1A,RHOA,CCND1,CDK2,IKBKB,CDK4,PAK1,RB1,AKT1,PIK3CA,CDK6,MAPK3,NFKB1,CCNE1,NFKBIA,PIK3R1,RAC1,MAPK1	0.055391018
BIOCARTA_MAPK_PATHWAY	MEF2C,JUN,MEF2D,MAX,MEF2BNB-MEF2B,CHUK,RAF1,MEF2A,STAT1,SHC1,ELK1,PAK2,CEBPA,MKNK1,MAP2K4,RIPK1,ATF2,RAPGEF2,MAPK9,MAP3K5,MAP4K3,MAPK10,MAPK11,MAP2K2,MAP4K4,BRAF,RPS6KA5,MAP2K3,MAP3K1,MAPK13,MAP3K3,MAP2K1,MAP3K4,MAP2K7,MAP3K10,MAP3K9,IKBKB,MAP2K5,MAP3K11,CREB1,MAP2K6,MAP3K7,MAP3K8,MAP3K12,MAP3K6,MAP4K1,MAP4K5,RPS6KA2,RPS6KA3,DAXX,RPS6KB1,RPS6KB2,GRB2,MAPK3,MAPK4,RPS6KA4,MAPK6,NFKB1,MAPK7,RAC1,NFKBIA,MYC,RPS6KA1,MAPK1,MAPKAPK3,HRAS,MAP4K2,MAPK8,MAPKAPK5,MAPK14,MAPK12,RELA,MAPKAPK2,TGFB2,MKNK2,TGFB1,TRAF2,ARAF,MAP3K14,TGFBR1,TRADD,TGFB3,PAK1,SP1,MAP3K13,FOS,MAP3K2	0.129292888
BIOCARTA_VIP_PATHWAY	EGR2,CALM2,CHUK,LOC124827,RELA,CALM1,PRKAR2B,PPP3CC,CYCSP35,LOC147908,MAP3K1,GNAQ,PRKACB,PRKACG,PPP3CB,EGR3,PPP3CA,PLCG1,VIPR2,PRKAR1A,PRKAR2A,VIP,PRKAR1B,CALM3,NFATC2,NFKB1,NFATC1,NFKBIA,MYC	0.099907956
BIOCARTA_NTHI_PATHWAY	MAPK11,CHUK,MAPK14,MAP2K3,EP300,RELA,NR3C1,TNF,IKBKB,MAP2K6,MAP3K7,DUSP1,MYD88,CREBBP,SMAD3,SMAD4,MAP3K14,TGFBR2,IL1B,TLR2,NFKB1,TGFBR1,NFKBIA,IL8	0.151754296
BIOCARTA_NFKB_PATHWAY	IKBKG,CHUK,MAP3K1,RELA,TNF,IKBKB,IL1A,MAP3K7,TNFRSF1B,TNFRSF1A,TRAF6,MYD88,FADD,TLR4,RIPK1,TNFAIP3,TAB1,MAP3K14,IL1R1,NFKB1,IRAK1,TRADD,NFKBIA	0.125396603
BIOCARTA_NUCLEARRS_PATHWAY	CYP2E1,ABCB4,ABCB1,RARA,PPARG,PPARD,PPARA,ABCB11,NR0B2,NR1I3,ABCC3,NR1H4,CYP1A2,NR1H3,IDDM11	0.087594285
BIOCARTA_PS1_PATHWAY	WNT1,NOTCH1,GSK3B,APC,BTRC,PSEN1,DVL1,CTNNB1,HNF1A,DLL1,FZD1,ADAM17,RBPJ,AXIN1	0.059144774
BIOCARTA_RAB_PATHWAY	RAB27A,RAB8A,RAB9A,RAB2A,RAB6A,RAB1A,ACTA1,RAB4A,RAB5A,RAB7A,RAB3A,RAB11A	0.239521436
BIOCARTA_RAS_PATHWAY	CASP9,HRAS,FOXO4,CHUK,RALA,RAF1,BCL2L1,ELK1,RELA,MAP2K1,RALBP1,RALGDS,AKT1,PIK3CA,RHOA,PLD1,MAPK3,BAD,NFKB1,PIK3CG,RAC1,PIK3R1,CDC42	0.136926314
BIOCARTA_MAL_PATHWAY	ROCK1,SRF,HRAS,MAP4K2,MAPK8,ACTA1,MAP2K2,RAF1,MAP3K1,MAP2K1,MAL,HNF1A,LIMK1,DIAPH1,RHOA,MAPK3,RAC1,CDC42,MAPK1	0.123107317
BIOCARTA_IL1R_PATHWAY	JUN,MAPK8,CHUK,MAPK14,RELA,TNF,TGFB2,TRAF6,MYD88,TGFB1,TOLLIP,IFNB1,IFNA1,ECSIT,IL1RAP,MAP3K14,IRAK2,IL1B,IL1R1,IRAK1,IL1RN,TGFB3,MAP2K3,MAP3K1,IRAK3,IKBKB,IL1A,MAP2K6,MAP3K7,TAB1,NFKB1,NFKBIA,IL6	0.208729214
BIOCARTA_TALL1_PATHWAY	TNFRSF13C,MAPK8,CHUK,MAPK14,RELA,TNFSF13,TNFSF13B,TNFRSF13B,TRAF6,TRAF5,TRAF3,TRAF2,TNFRSF17,MAP3K14,NFKB1	0.122186685
BIOCARTA_41BB_PATHWAY	JUN,MAP3K5,MAPK8,CHUK,MAPK14,MAP3K1,RELA,TNFRSF9,IKBKB,MAP4K5,IFNG,TRAF2,ATF2,IL4,NFKB1,NFKBIA,IL2	0.037685913
BIOCARTA_STRESS_PATHWAY	JUN,LTA,IKBKG,MAP4K2,MAPK8,CHUK,MAPK14,RELA,TNF,MAP2K4,CRADD,TRAF2,TANK,RIPK1,MAP3K14,TRADD,MAP2K3,MAP3K1,IKBKB,MAP2K6,CASP2,TNFRSF1A,ATF1,NFKB1,NFKBIA	0.14308845
BIOCARTA_TNFR2_PATHWAY	IKBKG,LTA,CHUK,IKBKAP,MAP3K1,RELA,IKBKB,TNFRSF1B,DUSP1,TRAF3,TRAF2,TANK,RIPK1,TNFAIP3,MAP3K14,NFKB1,TRAF1,NFKBIA	0.079179593
BIOCARTA_TOLL_PATHWAY	JUN,IKBKG,TLR10,MAPK8,TIRAP,CHUK,MAPK14,ELK1,RELA,TLR9,EIF2AK2,TRAF6,PPARA,MAP2K4,MYD88,TOLLIP,ECSIT,TAB2,PGLYRP1,MAP3K14,IRAK1,TLR6,MAP2K3,MAP3K1,LY96,IKBKB,MAP2K6,MAP3K7,CD14,TLR3,TLR4,TAB1,TLR7,FOS,TLR2,NFKB1,NFKBIA	0.187962238
ST_WNT_CA2_CYCLIC_GMP_PATHWAY	ITPR1,PDE6H,CAMK2D,PDE6D,CAMK2G,CAMK2A,PDE6C,CFB,PDE6B,TF,CAMK2B,NFAT5,ITPR2,PDE6A,ITPKA,PDE6G,SLC6A13,ITPR3,DAG1,ITPKB	0.131021673
ST_TUMOR_NECROSIS_FACTOR_PATHWAY	NFKBIA,MAP3K7,TNFRSF1A,MAP3K3,JUN,TNFRSF1B,NFKBIB,CASP3,NR2C2,BAG4,RIPK1,CFLAR,BIRC2,CASP8,NFKB2,TNF,MAP2K4,BIRC3,TRAF2,TRADD,IKBKG,TONSL,FADD,NFKBIE,AGFG1,TNFAIP3,NFKB1,RALBP1,NFKBIL1	0.072686212
SIG_CD40PATHWAYMAP	NFKBIA,MAPK14,TRAF3,MAPK3,MAPK8IP2,MAPK11,NFKBIB,MAPK8IP1,PIK3R1,PIK3CD,CD40,SYT1,NFKB2,TRAF6,MAP2K7,MAPKAPK5,DUSP1,MAPK13,MAP2K4,TRAF2,TRAF5,IKBKG,MAPK12,TONSL,MAPK8IP3,NFKBIE,MAPK9,PIK3CA,MAPK10,GORASP1,NFKB1,MAPK1,NFKBIL1,MAPK8	0.163727414
ST_GA12_PATHWAY	PLD1,RAF1,EPHB2,VAV1,PTK2,F2RL2,MAPK7,BTK,JUN,PLD3,CFB,F2RL3,F2,DLG4,MYEF2,PLD2,RASAL1,NR4A3,SRC,MAPK1,MAP2K5,MAPK8,F2RL1	0.126803932
ST_G_ALPHA_S_PATHWAY	RAF1,RAPGEF3,CAMP,BRAF,BFAR,CREB3,CFB,ASAH1,SNX13,CREB5,CREB1,MAPK1,SRC,TERF2IP,GAST,RASGRF2	0.104918165
ST_G_ALPHA_I_PATHWAY	EGFR,PLCB2,SOS1,AKT1,SOS2,AKT3,ITPR2,PIK3CB,TERF2IP,SHC1,DRD2,STAT3,ITPKB,ITPR1,RAF1,EPHB2,AKT2,KCNJ9,GRB2,PITX2,BRAF,KCNJ5,CFB,PLCB1,ASAH1,RGS20,PI3,ITPKA,PLCB4,SRC,MAPK1,KCNJ3,ITPR3,DAG1,PLCB3	0.212929509
ST_ADRENERGIC	GNA15,EGFR,MAPK14,AKT1,CCL13,PIK3R1,ITPR2,PIK3CD,CCL15,APC,ITPKB,ITPR1,RAF1,GNA11,GNAQ,GNAI1,KCNJ9,CAMP,PITX2,BRAF,KCNJ5,AR,CFB,PTX3,ASAH1,PIK3CA,MAPK10,ITPKA,SRC,MAPK1,KCNJ3,GAST,ITPR3,DAG1,CCL16,PHKA2	0.230442277
ST_GAQ_PATHWAY	NFKBIA,AKT1,VN1R1,NFKBIB,AKT3,ITPR2,PIK3CB,NFKB2,ITPKB,ITPR1,PLD1,GNAQ,PDK1,AKT2,IKBKG,TONSL,NFKBIE,PITX2,ADRBK1,CFB,PLD3,NFKB1,PLD2,ITPKA,NFKBIL1,ITPR3,DAG1,PHKA2	0.02447038
ST_GA13_PATHWAY	RDX,NFKBIA,AKT1,TBXA2R,NFKBIB,AKT3,PIK3CB,NFKB2,PLD1,PDK1,MAP2K4,AKT2,CDC42,SRF,BCL2,MAP3K1,PTK2,IKBKG,SERPINA4,TONSL,NFKBIE,CFB,PLD3,ARHGEF11,ROCK2,LPA,DLG4,ROCK1,GNA13,MAP3K5,PI3,PRKD1,NFKB1,PLD2,NFKBIL1,MAPK8,PHKA2	0.014208608
ST_T_CELL_SIGNAL_TRANSDUCTION	PAK4,LAT,ZAP70,VAV1,NFKBIA,SOS1,CTLA4,GRAP2,LCK,LCP2,PRDX1,PAK3,PTPRC,CSK,SOS2,NFAT5,NFKBIB,PAK6,NCK1,PLCG1,PAK1,ITK,CD3D,NFKB2,ITPKB,RAF1,EPHB2,RASGRP3,CBL,TONSL,NFKBIE,GRB2,RASGRP2,PAK7,RASGRP1,NFKB1,ITPKA,PAK2,RASGRP4,MAPK1,DTYMK,FBXW7,NFKBIL1,DAG1,CD28	0.082201212
ST_B_CELL_ANTIGEN_RECEPTOR	CD19,PPP1R13B,VAV1,NFKBIA,SOS1,PRDX1,AKT1,CSK,SOS2,NFKBIB,NFAT5,PIK3R1,AKT3,PIK3CD,MAP2K1,SHC1,BLNK,NFKB2,ITPKB,BCR,RAF1,EPHB2,AKT2,SERPINA4,TONSL,NFKBIE,LYN,GRB2,BTK,PIK3CA,PLCG2,BAD,PI3,MAP2K2,NFKB1,ITPKA,MAPK1,NFKBIL1,SYK,DAG1	0.177870721
ST_JNK_MAPK_PATHWAY	DUSP8,MAP3K10,PAPPA,MAP3K7,MAP3K3,GAB1,JUN,ATF2,AKT1,MAP3K13,GADD45A,TAB1,NFATC3,NR2C2,MAP3K11,SHC1,TRAF6,MAP2K7,DLD,MAP2K4,GCK,DUSP10,DUSP4,CDC42,MAP3K1,MAPK7,MAPK9,MAP3K2,TAB2,MAP3K9,ZAK,MAP3K5,MAP3K4,TP53,MAPK10,MYEF2,MAP3K12,MAP2K5,IL1R1,MAPK8	0.249324287
ST_FAS_SIGNALING_PATHWAY	TUFM,EZR,SMPD1,MET,NFKBIB,CASP3,PARP1,NR0B2,PFN1,CAD,MAP2K7,EPHB2,TRAF2,MAP3K1,HSPB1,MAPK8IP3,TONSL,AGFG1,BAK1,ROCK1,MAP3K5,TP53,MAPK10,FAS,DAXX,DIABLO,MAPK8,EGFR,NFKBIA,DEDD2,PFN2,BFAR,IL1A,MAPK8IP2,TPX2,FAIM2,NFAT5,MAPK8IP1,PTPN13,XIAP,BAX,RIPK1,CASP8,NFKB2,CASP10,CDK2AP1,MAP2K4,FAF1,ALG2,CD7,NFKBIE,IL8,FADD,TNFRSF6B,MAPK9,BTK,DEDD,CSNK1A1,NFKB1,RALBP1,CASP8AP2,MAPK1,NCS1,NFKBIL1,DFFA	0.151754296
ST_MYOCYTE_AD_PATHWAY	RAC1,RHO,AKT1,ITPR2,APC,ADRB1,ITPR1,GNAQ,EPHB2,GNAI1,KCNJ9,CAMP,PITX2,PLN,KCNJ5,CFB,KAT5,PTX3,ASAH1,CAV3,DLG4,RYR1,MAPK1,KCNJ3,GAST,ITPR3,DAG1	0.167592154
SA_REG_CASCADE_OF_CYCLIN_EXPR	E2F2,CDKN1B,E2F1,CDK2,CCNA2,PRB1,CCNA1,CCNE1,E2F4,CCND1,CDKN2A,CDK4,CCNE2	0.063443086
PID_BCR_5PATHWAY	IKBKG,BCL10,BLNK,PTPRC,HRAS,PAG1,PPP3CA,CD19,VAV2,NFKBIB,DAPP1,RASA1,BCL2A1,PDPK1,GRB2,DOK1,CD79A,PTPN6,SOS1,PTEN,MAPK3,AKT1,CHUK,CD72,MAPK8,PIK3CA,PPP3CC,MAP4K1,PIK3AP1,TRAF6,IKBKB,LYN,MAP3K7,CARD11,NFKB1,NFATC1,CSNK2A1,PIK3R1,PPP3CB,CAMK2G,INPP5D,CD22,FCGR2B,ETS1,SH3BP5,MAP3K1,MAPK1,MAP2K1,RELA,JUN,IBTK,CSK,NFKBIA,SYK,ELK1,MALT1,SHC1,PLCG2,FOS,POU2F2,MAPK14,CD79B,RAC1,RAF1,BTK	0.249881724
PID_LYSOPHOSPHOLIPID_PATHWAY	BCAR1,PLCB3,GNAI3,GSK3B,RELA,PTK2,ADCY1,LYN,ADCY7,PLD2,GNA12,GNAO1,HRAS,ADCY4,ADCY2,NFKBIA,NFKB1,ADCY8,EGFR,LPAR3,LPAR1,MAGI3,LPAR4,ADRA1B,GNB1,CRK,PRKCD,IL6,AKT1,PLCG1,TIAM1,ARHGEF1,GNA14,GNA11,LPAR2,ADCY9,RHOA,MMP9,GNAZ,PIK3CB,MMP2,PIK3R1,GNAI1,PTK2B,PRKCE,PXN,PRKD1,FOS,IL8,GAB1,ADCY6,JUN,RAC1,GNAI2,ADCY5,GNA13,GNAQ,MAPT,ADCY3,HBEGF,CASP3,GNA15,SRC,GNG2,TRIP6,SLC9A3R2	0.079263345
PID_NOTCH_PATHWAY	NCOR1,NOTCH1,DTX1,FURIN,SSPO,DLL1,DNM1,PTCRA,RAB11A,NEURL,CTBP1,FBXW7,NUMB,CBL,MFAP2,MYCBP,DLL4,MAML1,SPEN,MYC,SKP2,CNTN6,NOTCH2,PSEN1,MAML2,YY1,GATA3,ENO1,ITCH,IL4,APH1B,LNX1,NCOR2,RBPJ,CDKN1A,JAG2,ADAM12,DLK1,EPS15,DNER,SKP1,NOTCH3,RBBP8,NOTCH4,JAG1,APH1A,DLL3,PSENEN,MFAP5,NCSTN,CCND1,EP300,HDAC1,MARK2,MIB1,ADAM10,CUL1,CNTN1,KDM1A	0.0354943
PID_P73PATHWAY	TP53I3,ADA,FAS,PML,GRAMD4,D4S234E,PFDN5,WT1,EP300,PPAP2A,GATA1,YAP1,BIN1,GDF15,FBXO45,RCHY1,BAX,IL4R,MDM2,FLOT2,PLK3,CCNB1,S100A2,AFP,RNF43,MAPK11,TP73,KAT5,CDK6,SERPINE1,WWOX,BRCA2,CCNA2,GNB2L1,SIRT1,PIN1,BUB3,MYC,AEN,CDK1,MAPK14,DEDD,BBC3,CLCA2,JAG2,ABL1,PRKACB,CDK2,DCP1B,BCL2L11,PLK1,SFN,HEY2,JAK1,RELA,NDUFS2,ITCH,NEDD4L,PEA15,SP1,HAGH,TP53AIP1,RB1,NTRK1,RAD51,TP63,FASN,CHEK1,BAK1,IL1RAP,HSF1,UBE4B,SERPINA1,CCNE2,BUB1,FOXO3,TUBA1A,CDKN1A,CASP2	0.206852688
PID_WNT_NONCANONICAL_PATHWAY	YES1,PRKCZ,MAP3K7,TAB2,FLNA,CSNK1A1,CDC42,DAAM1,FZD7,WNT5A,ROR2,NFATC2,SETDB1,NLK,ROCK1,RAC1,ARRB2,FZD5,MAPK8,CHD7,MAPK9,PPARG,CAMK2A,DVL1,RHOA,FZD6,CTHRC1,DVL2,DVL3,FZD2,TAB1,MAPK10	0.079263345
PID_NFKAPPAB_ATYPICAL_PATHWAY	PIK3CA,NFKB1,CSNK2B,SYK,CSNK2A1,PIK3R1,SSPO,MAPK14,LCK,NFKBIA,RELA,SRC,BCL3,IKBKB,ARRB2,REL,CSNK2A2	0.129292888
PID_TCR_PATHWAY	SHC1,RASGRP1,AKT1,CD3D,HLA-DRB1,HRAS,IKBKB,PRKCA,CD86,RASGRP2,SH3BP2,TRAF6,IKBKG,ZAP70,PTPN6,NRAS,CBL,ORAI1,WAS,FYN,PRKCB,CD3E,NCK1,CHUK,PAG1,CSK,FLNA,BCL10,SLA2,HLA-DRA,GAB2,PLCG1,RAP1A,KRAS,LCK,RASSF5,LCP2,GRB2,CD80,GRAP2,MAP3K14,CD3G,PTPRC,LAT,PRKCQ,PTPN11,CD28,FYB,CD4,STK39,PTEN,ITK,CARD11,MAP3K8,PRKCE,MAP4K1,VAV1,TRPV6,CDC42,DBNL,PDPK1,CD247,SOS1,INPP5D,MALT1,STIM1	0.208729214
PID_NFKAPPAB_CANONICAL_PATHWAY	CYLD,UBE2D3,TNFAIP3,NFKBIA,XPO1,MALT1,BIRC2,TRAF6,NOD2,PRKCA,RELA,RAN,TNF,IKBKG,NFKB1,SSPO,IKBKB,RIPK2,BCL10,CHUK,ATM,ERC1,TNFRSF1A	0.017140543
PID_E2F_PATHWAY	E2F1,RBBP4,ATM,CEBPA,CBX5,CREBBP,YY1,MYC,POLA1,E2F7,HIC1,RYBP,RRM2,KAT2B,UXT,RB1,CDK2,WASF1,HDAC1,MCL1,CDC6,E2F5,RBL1,CES5A,CDK1,PLAU,EP300,KAT2A,HBP1,SULT2A1,E2F2,RBL2,CES1,CCNE1,MYBL2,CES3,TOPBP1,SMARCA2,E2F3,CES4A,CES2,TRIM28,CES1P1,CDC25A,E2F6,CCND3,CDKN1A,RANBP1,BRCA1,TP73,XRCC1,SERPINE1,RRM1,CDKN2C,ORC1,CDKN1B,CCNE2,TFDP2,DHFR,TK1,APAF1,CCNA2,CASP7,SP1,SIRT1,TRRAP,PRMT5,TFE3,CDKN2A,TYMS,MCM3,RBBP8,E2F4,TFDP1	0.231280201
PID_LPA4_PATHWAY	LPAR4,PRKACA,ADCY1,RPS6KA5,ADCY3,PRKCE,ADCY8,ADCY4,CREB1,ADCY7,GNAL,ADCY2,ADCY6,ADCY9,ADCY5	0.128403716
PID_AR_PATHWAY	AKT1,PAWR,HNRNPA1,PTK2B,NCOA4,CDK6,FHL2,CTDSP1,GSN,KLK3,KLK2,BRCA1,NRIP1,SVIL,VAV3,CTNNB1,CASP8,CTDSP2,RANBP9,CARM1,CDK11B,APPL1,HIP1,UBA3,TMPRSS2,NKX3-1,NCOA2,CDKN2A,RPS6KA3,PIAS4,KDM3A,PA2G4,KDM4C,MED1,FKBP4,CCND1,UBE3A,TMF1,PRDX1,PIAS1,XRCC6,CCND3,LATS2,UBE2I,TGIF1,ZNF318,XRCC5,PELP1,CMTM2,KDM1A,PRKDC,SRF,SNURF,TGFB1I1,ZMIZ1,PATZ1,AR,MAK,PIAS3,NCOA6,TCF4	0.107859121
PID_NFAT_TFPATHWAY	CREM,CTLA4,PTGS2,PRKCQ,CASP3,EGR1,IFNG,FOSL1,IL8,EGR2,PPARG,NFATC2,NFATC3,EGR3,TLE4,IL5,JUN,GBP3,IL4,POU2F1,TBX21,CDK4,FOS,CSF2,SLC3A2,IL2,NFATC1,IRF4,BATF3,FASLG,TNF,FOXP3,IL2RA,PTPRK,EGR4,DGKA,JUNB,E2F1,RNF128,IKZF1,IL3,PTPN1,MAF,GATA3,ITCH,CBLB,CD40LG	0.122186685
PID_AVB3_OPN_PATHWAY	VAV3,SYK,PLAU,MAPK8,ITGB3,MMP9,ROCK2,MAPK3,RELA,PTK2B,CHUK,MMP2,ITGAV,PIK3R1,SPP1,BCAR1,CD44,MAP3K1,NFKB1,FOS,CDC42,MAP3K14,MAPK1,JUN,NFKBIA,RHOA,RAC1,GSN,PIP5K1A,PIK3CA,ILK	0.107859121
PID_RHOA_REG_PATHWAY	SRGAP1,ARHGAP9,OPHN1,ARHGEF5,ARHGDIA,FARP1,RGNEF,CDKN1B,NET1,MCF2,TRIO,ARHGEF12,PLEKHG6,ARHGAP6,ARHGEF10L,ARHGEF15,MYO9B,ARHGEF10,ABR,MCF2L,ARHGEF3,RHOA,ARHGDIG,ARHGEF1,VAV1,BCR,VAV2,DEF6,OBSCN,AKAP13,ARAP3,ARHGEF25,DLC1,ARHGEF17,ARHGAP35,ARAP1,ARHGEF2,ARHGAP4,ARHGEF11,NGEF,ARHGAP8,ARHGDIB,ARHGAP5,ECT2,ARHGEF18,VAV3	0.127174075
PID_PS1_PATHWAY	TLE1,DKK1,PPP2R5D,APH1A,JUN,DLL1,KREMEN2,SSPO,HNF1A,AES,FBXW11,DTX1,CSNK1A1,LRP6,MAP3K7,PSEN1,CTNNB1,NCSTN,WNT1,NOTCH1,DKK2,NKD1,NEDD4,FRAT1,MAPK3,MYC,FZD1,DVL1,AXIN1,FOS,TAB1,APH1B,PSENEN,CSNK2A1,WIF1,PPARD,ADAM10,RBPJ,GSK3B,CTBP1,MAPK1,CREBBP,CCND1,NLK,HDAC1,APC	0.129292888
PID_TRAIL_PATHWAY	CFLAR,PIK3R3,IKBKG,MAPK1,MAP2K4,PIK3CB,MAPK8,TNFRSF10A,TNFRSF10D,MAPK3,FADD,TNFRSF10C,TNFRSF10B,DAP3,TNFSF10,TRADD,CASP10,IKBKB,RIPK1,CASP8,SMPD1,CHUK,MAP3K1,PIK3R2,PIK3R1,TRAF2,PIK3CD,PIK3CA	0.220269303
PID_HDAC_CLASSI_PATHWAY	MBD3,CREBBP,SIN3A,CHD3,SMAD7,STAT3,TNFRSF1A,PRKACA,MXD1,SIRT2,WDR77,FKBP3,RAN,SUMO1,SIRT5,YY1,NCOR2,HDAC6,MBD3L2,RANGAP1,HDAC1,RANBP2,RELA,NR2C1,HDAC9,RBBP4,RBBP7,HDAC3,NCOR1,SMURF1,SMG5,KAT2B,ZFPM1,HDAC10,HDAC4,MBD2,PRMT5,MTA2,NFKB1,NFKBIA,TFCP2,UBE2I,PPARG,MAX,CHD4,TNF,GATAD2B,SIRT3,SIRT4,HDAC2,GATA2,SAP18,HDAC11,SIN3B,XPO1,SAP30,SIRT6,SIRT1,GATA1,HDAC7,SIRT7,GATAD2A,SSPO,EP300,HDAC8,HDAC5	0.123071103
PID_HNF3B_PATHWAY	ALB,PCK1,BDH1,HNF1A,NF1,UCP2,NR3C1,F2,HNF4A,G6PC,ABCC8,SLC2A2,GCK,HMGCS1,PKLR,CEBPA,ACADVL,INS,FOXA1,TTR,ALDOB,KCNJ11,TFRC,AKT1,CEBPD,CREB1,ALAS1,CEBPB,HADH,IGFBP1,CPT1B,SP1,AFP,FOXA3,HNF1B,APOA1,CPT1C,NKX2-1,FOXA2,CPT1A,DLK1,ACADM,FOXF1,TAT,PDX1	0.005412803
PID_IL1_PATHWAY	UBE2N,MAP2K6,PIK3CA,CHUK,NFKB1,IKBKG,TRAF6,IL1R2,MAP3K3,RELA,MAP3K7,SQSTM1,PRKCI,IKBKB,TAB2,MYD88,PRKCZ,IL1RAP,UBE2V1,IRAK1,JUN,IL1B,MAPK8,TICAM2,ERC1,IRAK4,TAB1,PIK3R1,CASP1,IL1R1,IL1RN,IL1A,TOLLIP,IRAK3	0.135822904
PID_TNF_PATHWAY	TNF,MAP4K5,SMPD1,BAG4,TRAF1,RFFL,GNB2L1,NFKB1,STAT1,NSMAF,MAP3K5,TRADD,TAB2,IKBKB,PRKCZ,TNFAIP3,MAP4K4,TRAF2,RIPK1,CAV1,MAP3K3,PRKCI,BIRC3,IKBKG,CASP8,CHUK,FADD,MAP3K7,TXN,SQSTM1,MAP3K1,MAP4K3,MAP4K2,SMPD2,TAB1,MAP2K3,TNIK,NRK,MADD,MAP2K7,RELA,ADAM17,TNFRSF1B,CYLD,TNFRSF1A,BIRC2	0.212929509
PID_RXR_VDR_PATHWAY	RARB,NR4A1,NR1H2,VDR,RXRB,NR1H3,RXRG,PPARG,NCOA1,THRB,RARA,PPARD,FAM120B,PPARA,RXRA,RARG,TNF,RPS6KB1,TGFB1,THRA,NR1H4,NCOR2,SREBF1,BCL2,ABCA1,MED1	0.123071103
PID_AP1_PATHWAY	DMP1,IL4,MYC,TP53,COL1A2,NPPA,CCL2,FOSL1,GATA2,EGR1,CBFB,NR3C1,IL5,CDKN1B,HLA-A,IL2,MAFG,JUND,PLAU,TH,MAF,SP1,NTS,GJA1,TCF7L2,MMP9,ETS1,MYB,ELF1,NFATC3,CREB1,IL6,MT2A,TIMP1,DUSP1,DMTF1,ATF2,FOSL2,TRIP6,ACTA1,COPS5,CDK1,CYR61,CRTC1,FABP4,BAG1,EDN1,IL10,BCL2L11,EP300,CSF2,CCND1,JUNB,NFATC1,MMP1,FOSB,TGFB1,IL8,ATF3,AGT,HIF1A,PTEN,FOS,CDKN2A,ESR1,PENK,CTNNB1,IFNG,JUN,NFATC2	0.005412803
PID_PDGFRB_PATHWAY	SOS1,RAC1,BCAR1,ARPC4,MAPK1,HCK,FOS,PIK3R5,RAPGEF1,STAT5B,MYOCD,PAG1,WASF2,JUND,ARPC3,PPP2CA,FYN,MAPK10,YES1,GAB1,LRP1,DOK1,NCK2,BAIAP2,SLC9A3R1,ELK1,EPS8,PRKCA,PRKCD,CTTN,ARPC1B,DOCK4,ACTN4,PDGFRB,MAPK3,STAT1,VAV2,WASL,KRAS,LCK,ACTA2,YWHAQ,DNM2,ABI1,EIF2AK2,ARHGAP35,MAP2K2,ARAP1,JUN,CYFIP2,PIK3CA,RAB4A,PTPN11,RASA1,RAF1,PIN1,PIK3CG,SPHK1,ITGAV,ARPC5,PTPN1,PTPN2,PLCG1,PIK3R6,FGR,PIK3CB,ARHGDIA,YWHAH,PPP2R1A,PAK1,CRK,BRAF,MYC,SFN,YWHAE,SHC1,SRF,NCKAP1,MLLT4,PRKCE,JAK2,S1PR1,NCK1,PTPRJ,BRK1,ACTR3,YWHAG,PTEN,NRAS,PPP2R2B,CSK,ACTR2,BLK,MAPK8,RPS6KA3,TAGLN,HRAS,ARPC2,YWHAZ,SIPA1,CBL,STAT3,GRB2,ITGB3,PDGFB,KSR1,PIK3R3,STAT5A,MAPK9,GRB10,SLA,RAP1B,SLC9A3R2,MAP2K7,MAP2K4,RHOA,MAP2K1,ABL1,LYN,SRC,RAP1A,PLA2G4A,YWHAB,USP6NL,PIK3R1,PIK3CD,RAB5A,IQGAP1,PIK3R2	0.212929509
PID_HIV_NEF_PATHWAY	BAG4,CFLAR,FAS,BID,CASP7,BIRC3,BCL2,MAP3K14,DAXX,MAPK8,CRADD,CASP3,CASP9,TNFRSF1A,FADD,APAF1,TRAF2,FASLG,TNF,CHUK,RIPK1,CASP8,CD247,DFFA,MAP3K5,CYCS,NFKB1,TRADD,RELA,CASP6,DFFB,CASP2,NFKBIA,MAP2K7,TRAF1	0.19404442
PID_ERBB1_INTERNALIZATION_PATHWAY	CHMP3,RAB5A,CDC42,SHC1,ZFYVE28,SPRY2,EGF,RAF1,PIK3CA,NRAS,AMPH,PTK2,PIK3R1,UBE2D2,EGFR,PIK3CB,HRAS,PIK3R2,EPS15,SH3KBP1,DNM1,LRIG1,SRC,UBE2D3,KRAS,SOS1,EPN1,SYNJ1,STAMBP,HGS,ARHGEF7,TSG101,SH3GL2,CBL,ITSN1,PIK3R3,USP8,PIK3CD,GRB2,CBLB,UBE2D1	0.059144774
PID_BETA_CATENIN_NUC_PATHWAY	DKK4,CTNNB1,EP300,IL8,AR,SNAI2,YWHAZ,KRT1,TRRAP,TCF4,SALL4,SMARCA4,FGF4,TLE4,YWHAQ,TBL1XR1,TCF7L1,MYF5,TCF7L2,JUN,ADCY7,YWHAG,INCENP,DKK1,CHD8,YWHAB,PITX2,CDX1,RUVBL2,AXIN2,SSPO,KCNIP4,MITF,ID2,YWHAE,MED12,MMP9,TBL1X,CTNNBIP1,SFN,MDFIC,CDX4,MMP2,CYR61,TERT,NCOA2,COX2,ZCCHC12,CBY1,CTBP1,HBP1,NEUROG1,CUL1,SKP1,CDKN2A,TNIK,TCF7,AES,TLE1,TLE2,HDAC2,BCL9,CCND1,MYOG,VCAN,LEF1,YWHAH,XPO1,MYC,KLF4,CDH1,DVL3,T,SP5,CAMK4,HDAC1,CACNA1G,APC,IGF2BP1,CCND2	0.072686212
PID_P38_ALPHA_BETA_DOWNSTREAM_PATHWAY	PTGS2,MITF,KRT8,MEF2A,SLC9A1,ESR1,RPS6KA4,KRT19,MAPKAPK2,ATF2,MAPK11,JUN,GDI1,HSPB1,CEBPB,MAPKAPK5,ATF6,MAPK14,HBP1,CSNK2B,MKNK1,PLA2G4A,RPS6KA5,DDIT3,NOS2,EIF4E,EIF4EBP1,MAPKAPK3,ATF1,USF1,TP53,MEF2C,RAB5A,CSNK2A1,PPARGC1A,CREB1,CSNK2A2,ELK4	0.158910202
PID_PI3KCI_AKT_PATHWAY	BCL2L1,GSK3A,MAPKAP1,RICTOR,TBC1D4,RAF1,CASP9,HSP90AA1,MAP3K5,FOXO3,AKT3,PRKDC,YWHAQ,YWHAH,MTOR,FOXO1,YWHAG,CDKN1A,SFN,YWHAE,PDPK1,CHUK,PRKACA,BAD,KPNA1,YWHAZ,CDKN1B,YWHAB,AKT1,AKT2,GSK3B,SRC,MLST8,FOXO4,SLC2A4	0.234894946
PID_BARD1_PATHWAY	NPM1,UBE2L3,TP53,CDK2,ATM,FANCD2,RAD51,FANCA,RBBP8,FANCE,FANCL,RAD50,FANCC,BARD1,EWSR1,BRCA1,ATR,FANCF,PRKDC,XRCC5,MRE11A,FANCG,UBE2D3,PCNA,CSTF1,NBN,TOPBP1,XRCC6,CCNE1	0.164096837
PID_TOLL_ENDOGENOUS_PATHWAY	RHOA,HMGB1,LY96,TIRAP,BGN,IKBKB,IRAK1,IKBKG,HSPD1,CHUK,SFTPA1,IRAK2,VCAN,TLR2,TLR1,TLR3,TLR6,CD14,TICAM1,TLR4,SAA1,S100A9,S100A8,MYD88,IRAK4	0.189650507
PID_RB_1PATHWAY	PPP2CA,SMARCB1,TGFB2,RBP2,CCNE1,CDKN1A,RAF1,JUN,BRD2,BGLAP,CREBBP,CBX4,CEBPA,CDK4,SPI1,TBP,ATF2,RUNX2,SMARCA4,MAPK14,TFDP1,DNMT1,CKM,CTBP1,ATF7,E2F2,PAX3,MITF,UBTF,MET,SUV39H1,SFTPD,MAPK11,CCND3,SKP2,RBBP4,ELF1,ABL1,EP300,HDAC3,CDKN2A,CCNA2,E2F3,PPARG,E2F1,CCND1,CEBPD,CDKN1B,CDK2,MYOD1,HDAC1,TAF1,CDK6,CCND2,MAPK9,MDM2,GSC,E2F4,SIRT1,AATF,RB1,MEF2C,PPP2R3B,CEBPB,CSF2	0.122186685
REACTOME_G0_AND_EARLY_G1	CDK2,LIN54,DYRK1A,E2F1,E2F4,E2F5,LIN9,HDAC1,LOC441488,MYBL2,PCNA,LIN37,RBBP4,RBL1,RBL2,RBBP4P1,TFDP1,CCNA2,CCNA1,CCNE1,CCNE2,LIN52,CDK1,CDC6,CDC25A	0.079263345
REACTOME_SULFUR_AMINO_ACID_METABOLISM	CDO1,SLC25A10,CTH,AHCY,ETHE1,GCLC,GCLM,MAT2B,GOT1,MAT1A,MAT2A,MTAP,MTR,APIP,CSAD,ADI1,CNDP2,SQRDL,ENOPH1,BHMT,SUOX,TST,MRI1,CBS	0.243091117
REACTOME_SIGNALING_BY_EGFR_IN_CANCER	AKT3,ADAM10,SPRY1,SPRY2,STAM2,CDKN1A,CDKN1B,ADCY1,ADCY2,ADCY3,ADCY5,CDC37,ADCY6,ADCY7,ADCY8,CHUK,ADCY9,THEM4,AP2M1,AP2S1,CLTA,CLTC,CREB1,CSK,ADRBK1,AP2A1,AP2A2,AP2B1,EGF,EGFR,ADCY4,EPS15,AKT1,AKT2,FOXO1,FOXO3,PHLPP1,MTOR,RICTOR,GAB1,LRIG1,GRB2,GSK3A,EPN1,SH3KBP1,NR4A1,HRAS,HSP90AA1,ITPR2,ITPR3,KRAS,MDM2,FOXO4,NRAS,PDE1A,PDE1B,PDPK1,PIK3CA,PIK3R1,PLCG1,PRKACA,PRKACB,PRKACG,PRKAR1A,PRKAR1B,PRKAR2A,PRKAR2B,PRKCA,PRKCD,PRKCE,PRKCG,PAG1,MAPK1,MAPK3,MAP2K1,MAP2K2,BAD,PTEN,TRIB3,EPS15L1,RAF1,RPS6KB2,RPS27A,MLST8,SH3GL2,SHC1,SOS1,SRC,ADAM17,TSC2,RPS27AP11,LOC729120,LOC730418,UBA52,LOC731292,YWHAB,MAPKAP1,CALM1,STAM,ADAM12,CALM2,CALM3,CAMK4,CASP9,AKT1S1,CBL,HGS,CDK1,CDC42	0.131021673
REACTOME_PI3K_EVENTS_IN_ERBB4_SIGNALING	AKT3,CDKN1A,CDKN1B,CHUK,THEM4,CREB1,NRG4,HBEGF,ERBB4,EREG,AKT1,AKT2,FOXO1,FOXO3,PHLPP1,MTOR,RICTOR,GSK3A,NRG1,NR4A1,MDM2,FOXO4,PDPK1,PIK3CA,PIK3R1,BAD,PTEN,TRIB3,RPS6KB2,MLST8,BTC,TSC2,LOC729120,LOC731292,MAPKAP1,CASP9,AKT1S1,NRG2	0.248331533
REACTOME_PI3K_EVENTS_IN_ERBB2_SIGNALING	AKT3,CDKN1A,CDKN1B,CHUK,THEM4,CREB1,NRG4,HBEGF,EGF,EGFR,ERBB2,ERBB3,ERBB4,EREG,AKT1,AKT2,FOXO1,FOXO3,PHLPP1,MTOR,RICTOR,GAB1,GRB2,GSK3A,NRG1,NR4A1,MDM2,FOXO4,PDPK1,PIK3CA,PIK3R1,BAD,PTEN,TRIB3,RPS6KB2,MLST8,BTC,TSC2,LOC729120,LOC731292,MAPKAP1,CASP9,AKT1S1,NRG2	0.249324287
REACTOME_PPARA_ACTIVATES_GENE_EXPRESSION	MED6,MED16,CDK8,YAP1,NCOA2,PPARGC1A,GLIPR1,MED8,APOA5,PLIN2,PPARGC1B,CPT1A,CPT2,CREBBP,CTGF,CYP1A1,CYP4A11,CYP7A1,AGT,ABCA1,EP300,ESRRA,ALAS1,FABP1,ACSL1,MED19,FDFT1,FHL2,NCOA6,CDK19,MED13L,WWTR1,TIAM2,ANKRD1,TNFRSF21,MED4,GRHL1,HMGCR,HMGCS1,HMGCS2,APOA1,APOA2,ACADM,SLC27A1,FADS1,MED11,ARNTL,ME1,NFYA,NFYB,NPAS2,NRF1,G0S2,ACOX1,MED31,ANGPTL4,MED15,ABCB4,UGT1A9,PPARA,PPARG,MED1,MED18,MED9,MED29,TRIB3,RORA,RXRA,SMARCD3,SREBF1,SREBF2,SULT2A1,MED22,TBL1X,TEAD1,TEAD4,TEAD3,TXNRD1,TBL1XR1,MED25,NCOA3,MED10,TEAD2,PRIC285,NCOA1,PEX11A,HDAC3,CCNC,MED30,MED14,MED21,MED23,MED17,MED26,MED27,MED7,MED20,CD36,NR1D1,CLOCK,NCOR1,TGS1,MED24,MED12	0.128659461
REACTOME_RIP_MEDIATED_NFKB_ACTIVATION_VIA_DAI	RIPK3,CHUK,TICAM1,AGER,HMGB1,APP,IKBKB,NFKB2,NFKBIA,NFKBIB,RELA,S100A12,S100B,SAA1,TLR3,ZBP1,IKBKG,RIPK1	0.123071103
REACTOME_PRE_NOTCH_TRANSCRIPTION_AND_TRANSLATION	MAMLD1,CREBBP,E2F1,E2F3,EIF2C3,EIF2C4,EP300,SNW1,TNRC6B,KAT2A,EIF2C1,EIF2C2,TNRC6A,RBPJ,JUN,MOV10,LOC441488,NOTCH2,NOTCH3,NOTCH4,MAML3,TNRC6C,CCND1,TFDP1,TP53,LOC728030,MAML2,KAT2B,MAML1	0.093836015
REACTOME_MITOCHONDRIAL_PROTEIN_IMPORT	COX17,SLC25A13,TIMM17B,TIMM23B,TIMM17A,TOMM40,TIMM44,MTX2,DNAJC19,CHCHD4,GRPEL2,CS,HSCB,CYC1,TIMM8A,LDHD,PMPCA,FXN,SAMM50,FXC1,TIMM13,TIMM10,TIMM9,TIMM8B,GFER,COQ2,C18orf55,SLC25A4,SLC25A6,TIMM22,HSPA9,HSPD1,IDH3G,TOMM5,LOC440490,MTX1,ATP5A1,ACO2,ATP5B,PAM16,ATP5G1,TOMM7,TOMM22,BCS1L,LOC642727,LOC644589,LOC646675,LOC646677,LOC650667,LOC650674,TAZ,VDAC1,GRPEL1,SLC25A12,TIMM50,PMPCB,TOMM20,TOMM70A	0.163727414
REACTOME_SIGNALING_BY_NOTCH4	ADAM10,JAG1,NCSTN,DLL1,JAG2,NOTCH4,APH1A,DLL4,PSENEN,PSEN1,PSEN2,APH1B	0.133709655
REACTOME_REGULATION_OF_COMPLEMENT_CASCADE	CFHR3,CR1,CD55,CFH,CFI,CD46,PROS1,CFB,LOC653879,C2,C3,C4A,C4BPA,C4BPB	0.123071103
REACTOME_SIGNALING_BY_NOTCH2	ADAM10,JAG1,NCSTN,DLL1,JAG2,NOTCH2,APH1A,DLL4,PSENEN,PSEN1,PSEN2,APH1B	0.141424029
REACTOME_PRE_NOTCH_EXPRESSION_AND_PROCESSING	MAMLD1,ST3GAL6,TMED2,CREBBP,E2F1,E2F3,EIF2C3,EIF2C4,EP300,SNW1,TNRC6B,POFUT1,KAT2A,EIF2C1,B4GALT1,EIF2C2,TNRC6A,RBPJ,JUN,LFNG,MFNG,MOV10,LOC441488,NOTCH2,NOTCH3,NOTCH4,ATP2A1,ATP2A2,ATP2A3,FURIN,MAML3,POGLUT1,TNRC6C,RAB6A,CCND1,RFNG,SEL1L,ST3GAL3,TFDP1,TP53,LOC728030,MAML2,KAT2B,MAML1	0.196676524
REACTOME_PRE_NOTCH_PROCESSING_IN_GOLGI	ST3GAL6,TMED2,B4GALT1,LFNG,MFNG,NOTCH2,NOTCH3,NOTCH4,ATP2A1,ATP2A2,ATP2A3,FURIN,RAB6A,RFNG,SEL1L,ST3GAL3	0.187163095
REACTOME_TRIGLYCERIDE_BIOSYNTHESIS	AGPAT1,AGPAT2,AGPAT6,GPAT2,ACSL1,ACSL3,ACSL4,FASN,GPD1L,LPIN1,ACSL6,LCLAT1,LPCAT4,GK,GPD1,ACACA,ACLY,HSD17B12,ACSL5,ELOVL2,AGPAT5,AGPAT3,AGPAT4,GPAM,ELOVL5,ELOVL1,LPIN3,SLC25A1,ELOVL4,ELOVL6,LPCAT1,ELOVL7,ELOVL3,DGAT2,AGPAT9,DGAT1,TECR,LPIN2	0.005412803
REACTOME_SIGNALING_BY_BMP	FSTL1,SMAD1,SMAD4,SMAD5,SMAD6,SMAD7,SMURF1,GREM2,SMURF2,SKI,BMP2,BMPR1A,BMPR1B,BMPR2,LOC731429,UBE2D1,UBE2D3,CHRDL1,ACVR2A,NOG,ACVR2B,CER1,ZFYVE16	0.128403716
REACTOME_SMAD2_SMAD3_SMAD4_HETEROTRIMER_REGULATES_TRANSCRIPTION	CDK8,CDK9,CDKN2B,E2F4,E2F5,WWTR1,HDAC1,JUNB,SMAD2,SMAD3,SMAD4,SMAD7,MEN1,LOC441488,MYC,SERPINE1,RBL1,TGIF2,RPS27A,SP1,TFDP1,TGIF1,RPS27AP11,UBA52,CCNC,CCNT1,CCNT2	0.212929509
REACTOME_REGULATION_OF_HYPOXIA_INDUCIBLE_FACTOR_HIF_BY_OXYGEN	EGLN2,EGLN3,CREBBP,EP300,EPAS1,EPO,HIF1A,ARNT,EGLN1,HIF1AN,RPS27A,HIF3A,TCEB1P3,TCEB1,TCEB2,RPS27AP11,UBA52,UBE2D1,UBE2D2,UBE2D3,VEGFA,VHL,CA9,CUL2,RBX1	0.162785039
REACTOME_PHOSPHOLIPID_METABOLISM	COL4A3BP,LPCAT3,CEPT1,CDS1,PEMT,CDIPT,AGPAT1,AGPAT2,SPTLC1,NEU3,CHAT,PLA2G16,CHKA,CHKB,MGLL,PLD4,DEGS2,ACER1,SLC44A3,MBOAT2,NEU4,SGPP2,AGPAT6,CSNK1G2,PIK3R6,GPAT2,PPM1L,ARSK,MBOAT1,PHOSPHO1,SGMS2,PIKFYVE,PLD6,CERS3,SLC44A5,ARSG,SACM1L,GPD1L,LPIN1,PIP5K1C,SLC44A1,PIK3R5,PLD3,PITPNB,KDSR,LCLAT1,CERS6,LPCAT4,PLA2G4F,GALC,SUMF2,SGMS1,PLA2G2D,GBA,INPP5J,GLA,GLB1,GM2A,GPD1,PLA2G4D,SUMF1,CERS2,HADHA,HADHB,HEXA,HEXB,PLA2G2E,PIK3R4,ENPP7,ARSI,ACER2,ARSH,INPPL1,ARF1,ARF3,ARSA,ARSB,STS,ARSE,ARSF,ASAH1,ACHE,MTM1,NEU1,NEU2,OCRL,OSBP,PLA2G3,PNPLA8,PCYT1A,INPP5K,PIK3C2A,PIK3C2B,PIK3C2G,PIK3C3,PIK3CA,PIK3CB,PIK3CD,PIK3CG,PIK3R1,PIK3R2,PI4KA,PI4KB,PIP4K2A,PLA2G1B,PLA2G2A,PLA2G4A,PLA2G5,PLD1,PLD2,CRLS1,CTSA,LPCAT2,ETNK2,PI4K2B,AGPAT5,ACER3,PI4K2A,ETNK1,SMPD3,SMPD4,VAC14,PRKD1,GPCPD1,PSAP,INPP5E,ASAH2,SPHK2,AGPAT3,AGPAT4,CHPT1,PNPLA2,SLC44A2,PTEN,GPAM,GBA2,GBA3,PCYT2,MTMR14,PLA2G2F,CERK,LPIN3,ASAH2C,SMPD1,SMPD2,TAZ,LOC729155,LOC731292,UGCG,MBOAT7,CERS4,ARSJ,PLBD1,LPCAT1,PNPLA3,SLC44A4,PTDSS2,SGPP1,PLA2G12A,PIP5K1B,PIP4K2B,PLA2G6,PLA2G10,GNPAT,DGAT2,AGPAT9,PIK3R3,EPT1,DEGS1,PLA2G4C,PPAP2A,PPAP2C,PPAP2B,DGAT1,CDS2,MTMR1,INPP4B,SYNJ1,SYNJ2,SPHK1,SGPL1,MTMR3,MTMR2,CERS5,MTMR6,MTMR7,MTMR4,VAPB,VAPA,TPTE2,PCYT1B,PGS1,GAL3ST1,SPTLC2,LPIN2,PTDSS1,FIG4,LPGAT1	0.113425981
REACTOME_SYNTHESIS_OF_PA	AGPAT1,AGPAT2,AGPAT6,GPAT2,GPD1L,LCLAT1,LPCAT4,PLA2G2D,GPD1,PLA2G4D,PLA2G2E,PLA2G1B,PLA2G2A,PLA2G4A,PLA2G5,PLD1,PLD2,AGPAT5,AGPAT3,AGPAT4,GPAM,PLA2G2F,LPCAT1,PLA2G12A,PLA2G10,GNPAT,AGPAT9	0.100760389
REACTOME_OXYGEN_DEPENDENT_PROLINE_HYDROXYLATION_OF_HYPOXIA_INDUCIBLE_FACTOR_ALPHA	EGLN2,EGLN3,EPAS1,HIF1A,EGLN1,RPS27A,HIF3A,TCEB1P3,TCEB1,TCEB2,RPS27AP11,UBA52,UBE2D1,UBE2D2,UBE2D3,VHL,CUL2,RBX1	0.129292888
REACTOME_TRANSCRIPTIONAL_ACTIVITY_OF_SMAD2_SMAD3_SMAD4_HETEROTRIMER	CDK8,CDK9,CDKN2B,PARP1,E2F4,E2F5,WWTR1,HDAC1,JUNB,SMAD2,SMAD3,SMAD4,SMAD7,MEN1,LOC441488,MYC,SERPINE1,TRIM33,PPM1A,RBL1,TGIF2,RPS27A,SMURF2,SKI,SKIL,SP1,TFDP1,TGIF1,RPS27AP11,UBA52,UBE2D1,UBE2D3,USP9X,CCNC,CCNT1,CCNT2,NCOR1,NCOR2	0.059144774
REACTOME_DOWNREGULATION_OF_SMAD2_3_SMAD4_TRANSCRIPTIONAL_ACTIVITY	PARP1,HDAC1,SMAD2,SMAD3,SMAD4,TRIM33,PPM1A,TGIF2,RPS27A,SMURF2,SKI,SKIL,TGIF1,RPS27AP11,UBA52,UBE2D1,UBE2D3,USP9X,NCOR1,NCOR2	0.133709655
REACTOME_ALPHA_LINOLENIC_ACID_ALA_METABOLISM	ACOT8,ABCD1,ACSL1,ACAA1,HSD17B4,FADS1,ACOX1,ELOVL2,ELOVL5,SCP2,ABCD1P5,FADS2	0.079263345
REACTOME_SYNTHESIS_OF_PC	CEPT1,PEMT,CHAT,CHKA,CHKB,SLC44A3,PHOSPHO1,SLC44A5,LPIN1,SLC44A1,ACHE,PCYT1A,CHPT1,SLC44A2,LPIN3,SLC44A4,PCYT1B,LPIN2	0.190373224
REACTOME_GLYCEROPHOSPHOLIPID_BIOSYNTHESIS	LPCAT3,CEPT1,CDS1,PEMT,CDIPT,AGPAT1,AGPAT2,CHAT,PLA2G16,CHKA,CHKB,MGLL,PLD4,SLC44A3,MBOAT2,AGPAT6,GPAT2,MBOAT1,PHOSPHO1,PLD6,SLC44A5,GPD1L,LPIN1,SLC44A1,PLD3,PITPNB,LCLAT1,LPCAT4,PLA2G4F,PLA2G2D,GPD1,PLA2G4D,HADHA,HADHB,PLA2G2E,ACHE,PLA2G3,PNPLA8,PCYT1A,PLA2G1B,PLA2G2A,PLA2G4A,PLA2G5,PLD1,PLD2,CRLS1,LPCAT2,ETNK2,AGPAT5,ETNK1,GPCPD1,AGPAT3,AGPAT4,CHPT1,PNPLA2,SLC44A2,GPAM,PCYT2,PLA2G2F,LPIN3,TAZ,MBOAT7,PLBD1,LPCAT1,PNPLA3,SLC44A4,PTDSS2,PLA2G12A,PLA2G6,PLA2G10,GNPAT,DGAT2,AGPAT9,EPT1,PLA2G4C,DGAT1,CDS2,PCYT1B,PGS1,LPIN2,PTDSS1,LPGAT1	0.072686212
REACTOME_PI3K_AKT_ACTIVATION	AKT3,CDKN1A,CDKN1B,CHUK,THEM4,CREB1,AKT1,AKT2,FOXO1,FOXO3,PHLPP1,MTOR,RICTOR,GSK3A,NR4A1,IRS1,RHOA,MDM2,FOXO4,NGF,NTRK1,PDPK1,PIK3CA,PIK3CB,PIK3R1,PIK3R2,BAD,PTEN,TRIB3,RPS6KB2,MLST8,TSC2,LOC729120,LOC731292,MAPKAP1,CASP9,AKT1S1,IRS2	0.248331533
REACTOME_AKT_PHOSPHORYLATES_TARGETS_IN_THE_CYTOSOL	AKT3,CDKN1A,CDKN1B,CHUK,AKT1,AKT2,GSK3A,MDM2,BAD,TSC2,CASP9,AKT1S1	0.072807507
REACTOME_GAB1_SIGNALOSOME	AKT3,CDKN1A,CDKN1B,CHUK,THEM4,CREB1,CSK,EGF,EGFR,AKT1,AKT2,FOXO1,FOXO3,PHLPP1,MTOR,RICTOR,GAB1,GRB2,GSK3A,NR4A1,MDM2,FOXO4,PDPK1,PIK3CA,PIK3R1,PAG1,BAD,PTEN,TRIB3,RPS6KB2,MLST8,SRC,TSC2,LOC729120,LOC731292,MAPKAP1,CASP9,AKT1S1	0.231280201
REACTOME_FATTY_ACYL_COA_BIOSYNTHESIS	ACSL1,ACSL3,ACSL4,FASN,ACSL6,ACACA,ACLY,HSD17B12,ACSL5,ELOVL2,ELOVL5,ELOVL1,SLC25A1,ELOVL4,ELOVL6,ELOVL7,ELOVL3,TECR	0.125597077
REACTOME_REGULATION_OF_BETA_CELL_DEVELOPMENT	AKT3,AKT1,AKT2,FGF10,FOXO1,NR5A2,PTF1A,GCK,FOXA2,FOXA3,HNF4A,HNF4G,ONECUT1,HES1,IAPP,RBPJ,INS,INSM1,PDX1,MAFA,ONECUT3,NEUROD1,NKX2-2,NKX6-1,NEUROG3,PAX6,PKLR,SLC2A2,HNF1A,HNF1B	0.009185363
REACTOME_NEUROTRANSMITTER_RELEASE_CYCLE	UNC13B,CHAT,SLC32A1,ABAT,RIMS1,GAD1,GAD2,GLS2,GLS,HSPA8,MAOA,SLC38A2,SLC17A7,RAB3A,SLC5A7,SLC1A1,SLC1A6,SLC1A7,SLC6A1,SLC6A11,SLC6A12,SLC18A2,SLC18A3,SLC22A2,SNAP25,STX1A,STXBP1,VAMP2,SYN1,SYN2,SYT1,ALDH5A1,DNAJC5,SYN3	0.165596725
REACTOME_REGULATION_OF_GENE_EXPRESSION_IN_BETA_CELLS	AKT3,AKT1,AKT2,FOXO1,GCK,FOXA2,FOXA3,HNF4A,HNF4G,IAPP,INS,PDX1,MAFA,NEUROD1,NKX2-2,NKX6-1,PAX6,PKLR,SLC2A2,HNF1A	0.025764942
REACTOME_METABOLISM_OF_POLYAMINES	ADC,PAOX,AMD1,GOT1,MTAP,ODC1,APIP,SMOX,ADI1,ENOPH1,SAT1,SMS,SRM,AGMAT,MRI1	0.129292888
REACTOME_NOTCH_HLH_TRANSCRIPTION_PATHWAY	MAMLD1,CREBBP,SNW1,KAT2A,RBPJ,NOTCH2,NOTCH3,NOTCH4,MAML3,LOC728030,MAML2,KAT2B,MAML1	0.056151736
REACTOME_INTEGRATION_OF_ENERGY_METABOLISM	RAPGEF3,CDX2,AGPAT1,GNB5,ADCY1,ADCY2,ADCY3,RAPGEF4,ADCY5,ADCY6,ADCY7,CHRM3,ADCY8,ADCY9,GPR119,CTNNB1,ADRA2A,DPP4,ADCY4,FASN,PLCB1,SEC11A,KCNG2,GATA4,GCG,GCGR,GIP,GLP1R,GNA11,GNA15,GNAI1,GNAI2,GNAO1,GNAQ,GNAS,GNB1,GNB2,GNB3,GNG3,GNG4,GNG5,GNG7,GNG10,GNG11,GNGT1,GNGT2,FFAR1,SPCS1,SLC25A4,SLC25A5,GRP,SLC25A6,ACACA,ACACB,O3FAR1,INS,ISL1,ITPR2,ITPR3,KCNB1,KCNC2,KCNJ11,KCNS3,LEP,MARCKS,ACLY,PAX6,MLXIPL,PCSK1,PRKAG2,GNG13,PFKFB1,PKLR,PLCB2,PLCB3,GNG2,PPP2CA,PPP2CB,PPP2R1A,PPP2R1B,PPP2R5D,PRKAA2,PRKAB2,PRKACA,PRKACB,PRKACG,PRKAR1A,PRKAR1B,PRKAR2A,PRKAR2B,PRKCA,GNG12,RAP1A,RAP1B,GNB4,SPCS3,SLC2A1,SLC2A2,LOC653566,SNAP25,STK11,STX1A,STXBP1,ABCC8,VAMP2,SYT5,TALDO1,MLX,TKT,LOC730413,LOC730418,CACNA1A,CACNB2,CACNB3,IQGAP1,SEC11C,GNG8,AKAP5,GNA14,SPCS2	0.005412803
REACTOME_DOPAMINE_NEUROTRANSMITTER_RELEASE_CYCLE	RIMS1,RAB3A,SLC18A2,SNAP25,STX1A,STXBP1,VAMP2,SYN1,SYN2,SYT1,SYN3	0.099699458
REACTOME_CYTOSOLIC_TRNA_AMINOACYLATION	FARSB,AARS,DARS,EPRS,FARSA,GARS,HARS,IARS,KARS,MARS,NARS,LARS,PPA1,QARS,RARS,SARS,TARS,VARS,WARS,AIMP2,CARS,YARS,AIMP1,EEF1E1	0.013419241
REACTOME_ADENYLATE_CYCLASE_ACTIVATING_PATHWAY	ADCY1,ADCY2,ADCY3,ADCY5,ADCY6,ADCY7,ADCY8,ADCY9,ADCY4,GNAL	0.178665458
REACTOME_ADENYLATE_CYCLASE_INHIBITORY_PATHWAY	ADCY1,ADCY2,ADCY3,ADCY5,ADCY6,ADCY7,ADCY8,ADCY9,ADCY4,GNAI1,GNAI2,GNAI3,GNAL	0.201532244
REACTOME_DIABETES_PATHWAYS	CTDSP2,PREB,PDIA6,HYOU1,EXOC5,IGF2BP1,IGF2BP3,IGF2BP2,YIF1A,PDIA5,KDELR3,EXOC3,EXOSC8,KLHDC3,ADD1,EXOSC6,TPP1,CPE,SLC30A7,EXOC8,CTSG,DCTN1,DDIT3,DDX11,DCP2,EIF2S1,ERN1,EXTL3,F2,SEC31A,DIS3,ATF6,EXOSC7,EXOSC2,SEC11A,GCG,GH1,SERP1,SPCS1,GSK3A,ERO1L,HDGF,CXXC1,HSPA5,IGF2,IGFALS,IGFBP1,IGFBP2,IGFBP3,IGFBP4,IGFBP5,IGFBP6,KLK3,IL8,INS,ACADVL,KIF5B,LEP,LMNA,DNAJB9,MMP1,MMP2,ASNS,DDX12P,SULT1A4,MYO5A,ATF3,ATF4,NFYA,NFYB,PAPPA,PARN,EXOSC3,EXOSC1,PCSK1,PCSK2,MBTPS2,DNAJB11,GHRL,PLG,EXOSC9,EXOSC4,EXOC6,FKBP14,WIPI1,PPP2R5B,ARFGAP1,EXOC1,EXOC2,C19orf10,DNAJC3,EXOSC5,SRPRB,RAB27A,BCHE,EXOC4,SPCS3,PAPPA2,MBOAT4,CCL2,TSPYL2,ATF4P3,LOC644556,SHC1,SLC30A5,LOC653566,SNAP25,SRPR,SSR1,STX1A,SULT1A3,VAMP2,TLN1,HSP90B1,LOC730136,WFS1,XBP1,ZBTB17,PLA2G7,CALR,SYVN1,KHSRP,MBTPS1,SEC11C,ATP6V0D1,KLF4,EIF2AK3,GOSR2,EDEM1,HERPUD1,SPCS2,TATDN2,CUL7	0.010825606
REACTOME_PKA_MEDIATED_PHOSPHORYLATION_OF_CREB	ADCY1,ADCY2,ADCY3,ADCY5,ADCY6,ADCY7,ADCY8,ADCY9,CREB1,ADCY4,PRKACA,PRKACB,PRKACG,PRKAR1A,PRKAR1B,PRKAR2A,PRKAR2B,LOC730418	0.189366622
REACTOME_NUCLEAR_RECEPTOR_TRANSCRIPTION_PATHWAY	NR2E3,NR1H3,NR2C2AP,NR0B1,NR2F6,ESR1,ESR2,ESRRA,ESRRB,ESRRG,NR5A2,NR5A1,NR6A1,NR3C1,NRBP1,NRBF2,NR4A1,HNF4A,HNF4G,AR,NR3C2,NR4A2,PGR,PPARA,PPARD,PPARG,MED1,RARA,RARG,RORA,RORB,RORC,RXRA,RXRB,RXRG,NR2F1,THRA,THRB,NR2E1,LOC728381,LOC731106,NR1H2,VDR,NR4A3,NR0B2,NR1I2,NR1D1,NR1I3,NR1D2	0.158910202
REACTOME_G1_PHASE	CDK4,CDK6,CDK7,CDKN1A,CDKN1B,CDKN2A,CDKN2B,CDKN2C,CDKN2D,CKS1B,E2F1,E2F2,E2F3,E2F4,E2F5,PPP2R3B,MNAT1,LOC441488,PPP2CA,PPP2CB,PPP2R1A,PPP2R1B,PPP2R2A,RB1,RBL1,RBL2,CCND1,RPS27A,SKP1,SKP2,TFDP1,RPS27AP11,LOC729964,UBA52,CUL1,CCND2,CCND3,CCNH	0.034281086
REACTOME_SIGNALING_BY_PDGF	AKT3,CDKN1A,CDKN1B,ADCY1,ADCY2,ADCY3,ADCY5,ADCY6,ADCY7,ADCY8,CHUK,ADCY9,THEM4,COL1A1,COL1A2,COL2A1,COL3A1,COL4A1,COL4A2,COL4A3,COL4A4,COL4A5,COL5A1,COL5A2,COL6A1,COL6A2,COL6A3,COL9A1,COL9A2,COL9A3,CREB1,CRK,CRKL,ADRBK1,ADCY4,AKT1,AKT2,FOXO1,FOXO3,PHLPP1,MTOR,RICTOR,GRB2,GRB7,RAPGEF1,GSK3A,NR4A1,HRAS,ITPR2,ITPR3,KRAS,MDM2,FOXO4,NCK1,NRAS,FURIN,PDE1A,PDE1B,PDGFA,PDGFB,PDGFRA,PDGFRB,PDPK1,PIK3CA,PIK3CB,PIK3R1,PIK3R2,PLAT,PLCG1,PLG,PRKACA,PRKACB,PRKACG,PRKAR1A,PRKAR1B,PRKAR2A,PRKAR2B,PRKCA,PRKCD,PRKCE,PRKCG,MAPK1,MAPK3,PDGFC,MAP2K1,MAP2K2,BAD,PTEN,TRIB3,RAF1,RASA1,RPS6KB2,MLST8,SOS1,SPP1,SRC,STAT1,STAT3,STAT5A,STAT5B,STAT6,THBS1,THBS2,THBS3,THBS4,TSC2,LOC729030,LOC729120,LOC730418,LOC731292,YWHAB,MAPKAP1,CALM1,PDGFD,CALM2,CALM3,CAMK4,CASP9,AKT1S1,NCK2,BCAR1,CDK1	0.179106867
REACTOME_DOWNSTREAM_SIGNAL_TRANSDUCTION	AKT3,CDKN1A,CDKN1B,ADCY1,ADCY2,ADCY3,ADCY5,ADCY6,ADCY7,ADCY8,CHUK,ADCY9,THEM4,CREB1,CRK,CRKL,ADRBK1,ADCY4,AKT1,AKT2,FOXO1,FOXO3,PHLPP1,MTOR,RICTOR,GRB2,GRB7,RAPGEF1,GSK3A,NR4A1,HRAS,ITPR2,ITPR3,KRAS,MDM2,FOXO4,NCK1,NRAS,PDE1A,PDE1B,PDGFA,PDGFB,PDGFRA,PDGFRB,PDPK1,PIK3CA,PIK3CB,PIK3R1,PIK3R2,PLCG1,PRKACA,PRKACB,PRKACG,PRKAR1A,PRKAR1B,PRKAR2A,PRKAR2B,PRKCA,PRKCD,PRKCE,PRKCG,MAPK1,MAPK3,MAP2K1,MAP2K2,BAD,PTEN,TRIB3,RAF1,RASA1,RPS6KB2,MLST8,SOS1,SRC,STAT1,STAT3,STAT5A,STAT5B,STAT6,TSC2,LOC729030,LOC729120,LOC730418,LOC731292,YWHAB,MAPKAP1,CALM1,CALM2,CALM3,CAMK4,CASP9,AKT1S1,NCK2,BCAR1,CDK1	0.125396603
REACTOME_ACTIVATION_OF_CHAPERONE_GENES_BY_XBP1S	CTDSP2,PREB,PDIA6,HYOU1,YIF1A,PDIA5,KDELR3,KLHDC3,ADD1,TPP1,DCTN1,DDX11,EXTL3,SEC31A,SERP1,GSK3A,HDGF,CXXC1,ACADVL,LMNA,DNAJB9,DDX12P,SULT1A4,DNAJB11,FKBP14,WIPI1,PPP2R5B,ARFGAP1,C19orf10,DNAJC3,SRPRB,TSPYL2,SHC1,SRPR,SSR1,SULT1A3,TLN1,WFS1,XBP1,ZBTB17,SYVN1,ATP6V0D1,GOSR2,EDEM1,TATDN2,CUL7	0.008209418
REACTOME_REGULATION_OF_INSULIN_SECRETION	RAPGEF3,CDX2,GNB5,RAPGEF4,ADCY5,ADCY6,CHRM3,ADCY8,GPR119,CTNNB1,ADRA2A,DPP4,PLCB1,SEC11A,KCNG2,GATA4,GCG,GIP,GLP1R,GNA11,GNA15,GNAI1,GNAI2,GNAO1,GNAQ,GNAS,GNB1,GNB2,GNB3,GNG3,GNG4,GNG5,GNG7,GNG10,GNG11,GNGT1,GNGT2,FFAR1,SPCS1,SLC25A4,SLC25A5,GRP,SLC25A6,O3FAR1,INS,ISL1,ITPR2,ITPR3,KCNB1,KCNC2,KCNJ11,KCNS3,LEP,MARCKS,PAX6,PCSK1,GNG13,PLCB2,PLCB3,GNG2,PRKACA,PRKACB,PRKACG,PRKAR1A,PRKAR1B,PRKAR2A,PRKAR2B,PRKCA,GNG12,RAP1A,RAP1B,GNB4,SPCS3,SLC2A1,SLC2A2,LOC653566,SNAP25,STX1A,STXBP1,ABCC8,VAMP2,SYT5,LOC730413,LOC730418,CACNA1A,CACNB2,CACNB3,IQGAP1,SEC11C,GNG8,AKAP5,GNA14,SPCS2	0.008209418
REACTOME_UNFOLDED_PROTEIN_RESPONSE	CTDSP2,PREB,PDIA6,HYOU1,YIF1A,PDIA5,KDELR3,EXOSC8,KLHDC3,ADD1,EXOSC6,TPP1,DCTN1,DDIT3,DDX11,DCP2,EIF2S1,ERN1,EXTL3,SEC31A,DIS3,ATF6,EXOSC7,EXOSC2,SERP1,GSK3A,HDGF,CXXC1,HSPA5,IGFBP1,IL8,ACADVL,LMNA,DNAJB9,ASNS,DDX12P,SULT1A4,ATF3,ATF4,NFYA,NFYB,PARN,EXOSC3,EXOSC1,MBTPS2,DNAJB11,EXOSC9,EXOSC4,FKBP14,WIPI1,PPP2R5B,ARFGAP1,C19orf10,DNAJC3,EXOSC5,SRPRB,CCL2,TSPYL2,ATF4P3,SHC1,SRPR,SSR1,SULT1A3,TLN1,HSP90B1,LOC730136,WFS1,XBP1,ZBTB17,CALR,SYVN1,KHSRP,MBTPS1,ATP6V0D1,EIF2AK3,GOSR2,EDEM1,HERPUD1,TATDN2,CUL7	0.034147436
REACTOME_CLASS_B_2_SECRETIN_FAMILY_RECEPTORS	CALCRL,RAMP2,RAMP1,RAMP3,GNB5,FZD10,PTH2,ADCYAP1,ADCYAP1R1,ADM,CRH,CRHR2,CD55,EMR1,FZD2,GCG,GCGR,GHRH,GHRHR,GIP,GIPR,GLP1R,GNAS,GNB1,GNB2,GNB3,GNG3,GNG4,GNG5,GNG7,GNG10,GNG11,GNGT1,GNGT2,EMR2,IAPP,IHH,DHH,WNT16,GNG13,GNG2,WNT4,GNG12,PTCH1,PTH,PTHLH,PTH1R,PTH2R,GNB4,SCT,SCTR,SHH,LOC649279,SMO,VIP,VIPR1,VIPR2,WNT1,WNT2,WNT3,WNT5A,WNT6,WNT7A,WNT7B,WNT8B,WNT10B,WNT11,WNT2B,WNT9A,WNT9B,FZD5,CALCA,CALCB,FZD3,ADM2,WNT10A,FZD1,FZD4,FZD6,FZD7,FZD8,FZD9,EMR3,PTCH2,WNT3A,GLP2R,GNG8,CD97	0.178665458
REACTOME_TRANSPORT_OF_GLUCOSE_AND_OTHER_SUGARS_BILE_SALTS_AND_ORGANIC_ACIDS_METAL_IONS_AND_AMINE_COMPOUNDS	SLC22A7,SLC2A6,SLC6A14,SLC2A13,SLC5A11,SLC22A12,SLC44A3,SLC31A1,CP,SLC47A2,SLC30A7,SLC2A12,SLC2A7,SLC30A8,SLC44A5,SLC44A1,SLC16A8,SLC41A1,SLC39A6,SLC39A1,SLC39A5,SLC13A5,SLC39A3,SLC39A2,SLC2A8,SLC40A1,SLC6A19,SLC10A6,SLC6A18,SLC22A18,RHCG,SLC6A20,SLC6A15,SLC47A1,SLC22A15,SLC39A4,SLC22A11,SLC2A9,SLC44A2,SLC39A10,RHAG,SLC5A7,SLC39A8,SLC13A3,SLC30A5,SLC2A1,SLC2A2,SLC2A3,SLC2A4,SLC2A5,SLC5A1,SLC5A2,SLC5A3,SLC6A1,SLC6A2,SLC6A3,SLC6A6,SLC6A7,SLC6A9,SLC6A11,SLC6A12,SLC11A1,SLC13A1,SLC14A1,SLC16A1,SLC18A1,SLC18A2,SLC22A1,SLC22A3,SLC22A2,SLC22A4,SLC22A5,SLC2A11,SLC30A1,SLC30A2,SLC30A3,SLC39A7,SLC44A4,SLC2A10,SLC14A2,SLC41A2,SLC22A16,SLC13A2,SLC16A3,SLC6A5,SLC16A7,SLC22A6,SLC22A8,HEPH	0.106038315
REACTOME_G_ALPHA_S_SIGNALLING_EVENTS	CALCRL,RAMP2,RAMP1,RAMP3,GNB5,ADCY1,ADCY2,CGA,PDE10A,ADCY3,ADCY5,ADCY6,ADCY7,PTH2,ADCY8,ADCY9,ADCYAP1,ADCYAP1R1,RLN3,RXFP2,ADM,TAAR1,ADORA2A,ADORA2B,CRH,CRHR2,GPBAR1,ADRB1,ADRB2,ADRB3,DRD1,DRD5,ADCY4,FSHB,FSHR,GCG,GCGR,GHRH,GHRHR,GIP,GIPR,PDE7B,GLP1R,GNAI1,GNAI2,GNAI3,GNAS,GNAZ,GNB1,GNB2,GNB3,GNG3,GNG4,GNG5,GNG7,GNG10,GNG11,GNGT1,GNGT2,TAAR6,HRH2,HTR4,HTR6,HTR7,IAPP,INSL3,NPSR1,LHB,LHCGR,MC1R,MC2R,MC3R,MC4R,MC5R,P2RY11,PDE11A,PDE1A,PDE2A,PDE3A,PDE3B,PDE4B,PDE4C,PDE4D,PDE7A,PDE8A,PDE1B,GNG13,GNG2,POMC,AVP,AVPR2,GNG12,PTGDR,PTGER2,PTGER4,PTGIR,PTH,PTHLH,PTH1R,PTH2R,GNB4,RXFP1,NPS,RLN2,SCT,SCTR,TSHB,TSHR,LOC730002,VIP,VIPR1,VIPR2,CALCA,CALCB,ADM2,TAAR8,PDE8B,TAAR5,TAAR2,GLP2R,GNG8	0.079263345
REACTOME_RECEPTOR_LIGAND_BINDING_INITIATES_THE_SECOND_PROTEOLYTIC_CLEAVAGE_OF_NOTCH_RECEPTOR	ADAM10,JAG1,DLL1,JAG2,NOTCH2,NOTCH3,NOTCH4,DLL4,RPS27A,ADAM17,RPS27AP11,UBA52	0.062848657
REACTOME_ZINC_TRANSPORTERS	SLC30A7,SLC30A8,SLC39A6,SLC39A1,SLC39A5,SLC39A3,SLC39A2,SLC39A4,SLC39A10,SLC39A8,SLC30A5,SLC30A1,SLC30A2,SLC30A3,SLC39A7	0.005412803
REACTOME_METAL_ION_SLC_TRANSPORTERS	SLC31A1,CP,SLC30A7,SLC30A8,SLC41A1,SLC39A6,SLC39A1,SLC39A5,SLC39A3,SLC39A2,SLC40A1,SLC39A4,SLC39A10,SLC39A8,SLC30A5,SLC11A1,SLC30A1,SLC30A2,SLC30A3,SLC39A7,SLC41A2,HEPH	0.005412803
REACTOME_MITOTIC_G1_G1_S_PHASES	CDK2,CDK4,CDK6,PSMD14,CDK7,CDKN1A,CDKN1B,CDKN2A,CDKN2B,CDKN2C,CDKN2D,DBF4,CKS1B,LIN54,DHFR,DYRK1A,E2F1,E2F2,E2F3,E2F4,E2F5,ORC6,ORC3,POLA2,FBXO5,PPP2R3B,LIN9,RPA4,HDAC1,MAX,MCM2,MCM3,MCM4,MCM5,MCM6,MCM7,MNAT1,LOC441488,MYBL2,MYC,ORC1,ORC2,ORC4,ORC5,PCNA,POLA1,POLE,POLE2,PPP2CA,PPP2CB,PPP2R1A,PPP2R1B,PPP2R2A,MCM10,PRIM1,PRIM2,LIN37,PSMA1,PSMA2,PSMA3,PSMA4,PSMA5,PSMA6,PSMA7,PSMB1,PSMB2,PSMB3,PSMB4,PSMB5,PSMB6,PSMB7,PSMB8,PSMB9,PSMB10,PSMC1,PSMC2,PSMC3,PSMC4,PSMC5,PSMC6,PSMD1,PSMD2,PSMD3,PSMD4,PSMD5,PSMD7,PSMD8,PSMD9,PSMD10,PSMD11,PSMD12,PSMD13,PSME1,PSME2,RB1,RBBP4,RBL1,RBL2,CCND1,RPA1,RPA2,RPA3,RPS27A,RRM2,RBBP4P1,DHFRP1,LOC645084,SKP1,SKP2,LOC652826,TFDP1,TK2,RPS27AP11,TYMS,LOC729964,UBA52,WEE1,CDT1,CDC7,CDC45,MCM8,CUL1,CCNA2,CCNA1,CCNB1,CCND2,CCND3,CCNE1,CCNH,PKMYT1,CCNE2,LIN52,PSMF1,CDK1,PSMD6,CDC6,CDC25A	0.142111339
REACTOME_TAK1_ACTIVATES_NFKB_BY_PHOSPHORYLATION_AND_ACTIVATION_OF_IKKS_COMPLEX	NOD1,TAB1,CHUK,AGER,TAB2,TAB3,HMGB1,APP,IKBKB,IRAK1,IRAK2,NFKB2,NFKBIA,NFKBIB,RELA,S100A12,S100B,SAA1,NOD2,MAP3K7,TRAF6,IKBKG,RIPK2	0.131021673
REACTOME_EFFECTS_OF_PIP2_HYDROLYSIS	RASGRP1,RASGRP2,MGLL,DGKK,DGKA,DGKB,DGKG,DGKH,DGKQ,DAGLB,ITPR2,ITPR3,PRKCD,PRKCE,PRKCH,PRKCQ,TRPC7,TRPC3,TRPC6,LOC730221,LOC730335,DAGLA,DGKE,DGKD,DGKI	0.183638364
REACTOME_L1CAM_INTERACTIONS	RANBP9,STIP1,AP2M1,AP2S1,CLTA,CLTC,CNTN1,CSNK2A1,CSNK2A2,CSNK2B,NCAN,AP2A1,AP2A2,AP2B1,DCX,DLG1,DLG3,DNM1,DNM2,DPYSL2,EGFR,ALCAM,FGFR1,KIF4A,CNTN6,RPS6KA6,LAMA1,KIF4B,ANK1,ANK3,ITGA1,ITGA2,ITGA2B,ITGA5,ITGA9,ITGAV,ITGB1,ITGB3,KCNQ2,KCNQ3,L1CAM,LAMB1,LAMC1,MSN,NCAM1,NRCAM,PAK1,SPTBN5,SCN3B,MAPK1,MAPK3,MAP2K1,MAP2K2,KIAA1598,SPTBN4,RAC1,RDX,RPS6KA1,RPS6KA2,RPS6KA3,SCN1B,SCN2A,SCN2B,SCN4A,SCN5A,SCN7A,SCN8A,SDCBP,SH3GL2,LOC650400,SPTA1,SPTAN1,SPTB,SPTBN1,SPTBN2,SRC,CNTN2,LOC731231,EZR,CNTNAP1,NUMB,NRP2,NRP1,RPS6KA4,RPS6KA5,CD24	0.157060134
REACTOME_INTERACTION_BETWEEN_L1_AND_ANKYRINS	ANK1,ANK3,KCNQ2,KCNQ3,L1CAM,NRCAM,SPTBN5,SCN3B,SPTBN4,SCN1B,SCN2A,SCN2B,SCN4A,SCN5A,SCN7A,SCN8A,LOC650400,SPTA1,SPTAN1,SPTB,SPTBN1,SPTBN2,LOC731231	0.206947328
REACTOME_FATTY_ACID_TRIACYLGLYCEROL_AND_KETONE_BODY_METABOLISM	MED6,MED16,CDK8,YAP1,NCOA2,AGPAT1,AGPAT2,PPARGC1A,GLIPR1,MED8,APOA5,PLIN2,PPARGC1B,CPT1A,CPT1B,CPT2,AGPAT6,CREBBP,CTGF,GPAT2,CYP1A1,CYP4A11,CYP7A1,ECI1,DECR1,AGT,ECHS1,ABCA1,EP300,ESRRA,ALAS1,FABP1,ACSL1,ACSL3,ACSL4,FASN,MED19,FDFT1,FHL2,NCOA6,CDK19,GPD1L,LPIN1,ACSL6,SIN3B,MED13L,LCLAT1,LPCAT4,WWTR1,SIN3A,TIAM2,ANKRD1,GK,TNFRSF21,GPD1,GPD2,MED4,GRHL1,HADHA,HADHB,HADH,ACACA,HMGCL,HMGCR,HMGCS1,HMGCS2,ACACB,ACADL,APOA1,APOA2,ACADM,ACADS,ACADVL,SLC27A1,ACAT1,FADS1,MED11,ARNTL,ME1,MUT,ACLY,NFYA,NFYB,NPAS2,NRF1,OXCT1,G0S2,PCCA,PCCB,ACOX1,MED31,ANGPTL4,HSD17B12,PRKAG2,MED15,ACSL5,ABCB4,UGT1A9,PPARA,PPARG,MED1,MED18,ELOVL2,MED9,AGPAT5,MED29,PRKAA2,PRKAB2,AGPAT3,AGPAT4,GPAM,TRIB3,ELOVL5,RORA,BDH1,RXRA,ELOVL1,LPIN3,SLC25A1,SMARCD3,SREBF1,SREBF2,ELOVL4,SULT2A1,MED22,TBL1X,TEAD1,TEAD4,TEAD3,TXNRD1,SLC25A20,ELOVL6,TBL1XR1,LPCAT1,ELOVL7,MED25,NCOA3,ELOVL3,MED10,TEAD2,DGAT2,MCEE,AGPAT9,PRIC285,NCOA1,DGAT1,PEX11A,HDAC3,CCNC,MED30,MED14,MED21,MED23,MED17,MED26,MED27,MED7,MED20,CD36,TECR,NR1D1,CLOCK,NCOR1,NCOR2,LPIN2,TGS1,MED24,MED12	0.009472405
REACTOME_IL1_SIGNALING	NOD1,TAB1,IRAK3,CHUK,MAP3K8,TAB2,PELI3,TAB3,IKBKB,IL1A,IL1B,IL1R1,IL1RAP,IL1RN,IRAK1,IRAK2,TMEM189-UBE2V1,MAP3K3,MYD88,IRAK4,TOLLIP,MAP2K1,MAP2K6,PELI2,PELI1,NOD2,MAP2K4,SKP1,MAP3K7,TRAF6,UBE2N,IL1R2,TNIP2,CUL1,IKBKG,RIPK2,SQSTM1,BTRC,RBX1	0.223364283
REACTOME_SYNTHESIS_SECRETION_AND_INACTIVATION_OF_GIP	GPR119,DPP4,SEC11A,GATA4,GIP,FFAR1,SPCS1,ISL1,PAX6,PCSK1,SPCS3,LOC653566,SEC11C,SPCS2	0.171783946
REACTOME_INCRETIN_SYNTHESIS_SECRETION_AND_INACTIVATION	CDX2,GPR119,CTNNB1,DPP4,SEC11A,GATA4,GCG,GIP,GNB3,FFAR1,SPCS1,GRP,O3FAR1,ISL1,LEP,PAX6,PCSK1,GNG13,SPCS3,LOC653566,SEC11C,SPCS2	0.155511346
REACTOME_IRAK1_RECRUITS_IKK_COMPLEX	CHUK,PELI3,IKBKB,IRAK1,TMEM189-UBE2V1,PELI2,PELI1,TRAF6,UBE2N,IKBKG	0.122186685
REACTOME_TRAF6_MEDIATED_NFKB_ACTIVATION	CHUK,AGER,DDX58,HMGB1,APP,IKBKB,MAP3K1,NFKB2,NFKBIA,NFKBIB,MAVS,RELA,S100A12,S100B,SAA1,IFIH1,TRAF2,TRAF6,TRIM25,RNF135,IKBKG	0.087594285
REACTOME_FACTORS_INVOLVED_IN_MEGAKARYOCYTE_DEVELOPMENT_AND_PLATELET_PRODUCTION	SH2B3,KIF20A,CDK2,CDK5,HMG20B,SH2B2,EHD1,KIF2C,AKAP10,VPS45,HIST2H3C,CREBBP,GATA5,KLC3,ZFPM1,DOCK1,DOCK2,DOCK3,EP300,JMJD1C,KIFAP3,KDM1A,RCOR1,DOCK9,ZFPM2,CBX5,MAFF,KIF4A,ABL1,SIN3A,SH2B1,KIF26A,GATA1,GATA2,GATA3,GATA4,GATA6,KIF4B,RACGAP1,H3F3A,H3F3B,HBB,HBD,HBE1,HBG2,HDAC1,HDAC2,EHD2,HIST2H3A,IFNA1,IFNA2,IFNA4,IFNA5,IFNA6,IFNA7,IFNA8,IFNA10,IFNA14,IFNA16,IFNA17,IFNA21,IFNB1,H3F3AP5,IRF1,IRF2,IRF3,IRF7,ITPK1,JAK2,KIF2A,KIF3C,KIF5A,KIF5B,KLC1,KIF11,KIFC1,KIF22,MAFG,LOC441511,MYB,NFE2,AK3,DOCK10,PRKACA,MFN1,PRKACB,PRKACG,PRKAR1A,PRKAR1B,PRKAR2A,PRKAR2B,KIF15,DOCK6,RAB5A,RAC1,RAD51C,RAD51B,ZFYVE20,KIF9,H3F3AP6,KLC2,HIST2H3D,TP53,LOC730418,LOC731820,WEE1,MAFK,DOCK5,AKAP1,DOCK8,CABLES2,KIF18A,CAPZA1,CAPZA2,HIST1H3A,HIST1H3D,HIST1H3C,HIST1H3E,HIST1H3I,HIST1H3G,HIST1H3J,HIST1H3H,HIST1H3B,KIF2B,HIST1H3F,KLC4,CABLES1,KIF3B,KIF23,DOCK4,MFN2,CDC42	0.090113146
REACTOME_NFKB_ACTIVATION_THROUGH_FADD_RIP1_PATHWAY_MEDIATED_BY_CASPASE_8_AND10	CHUK,DDX58,IKBKB,MAVS,IFIH1,TRIM25,CASP8,RNF135,CASP10,IKBKG,RIPK1,FADD	0.123107317
REACTOME_INTERFERON_ALPHA_BETA_SIGNALING	ADAR,IRF9,IFITM3,IFITM2,USP18,LOC144383,EGR1,IFI6,GBP2,HLA-A,HLA-B,HLA-C,HLA-F,HLA-G,IRF8,IFI27,IFI35,IFIT2,IFIT1,IFIT3,IFNA1,IFNA2,IFNA4,IFNA5,IFNA6,IFNA7,IFNA8,IFNA10,IFNA14,IFNA16,IFNA17,IFNA21,IFNAR1,IFNAR2,IFNB1,IRF1,IRF2,IRF3,IRF4,IRF5,IRF6,IRF7,ISG20,JAK1,MX1,MX2,OAS1,OAS2,OAS3,IP6K2,XAF1,PSMB8,PTPN1,PTPN6,RNASEL,HLA-K,STAT1,STAT2,TYK2,IFITM1,OASL,SOCS1,SOCS3,ISG15	0.242800788
REACTOME_KINESINS	KIF20A,KIF2C,KLC3,KIFAP3,KIF4A,KIF26A,KIF4B,RACGAP1,KIF2A,KIF3C,KIF5A,KIF5B,KLC1,KIF11,KIFC1,KIF22,KIF15,KIF9,KLC2,KIF18A,KIF2B,KLC4,KIF3B,KIF23	0.020954109
REACTOME_NEGATIVE_REGULATORS_OF_RIG_I_MDA5_SIGNALING	CYLD,DDX58,TBK1,UBE2K,IRF3,PCBP2,HERC5,PIN1,RNF125,OTUD5,MAVS,RPS27A,IFIH1,TNFAIP3,TRAF3,RPS27AP11,UBA52,UBA7,UBE2D1,UBE2D2,UBE2D3,TRIM25,NLRX1,NLRC5,RNF135,TAX1BP1,ATG12,UBE2L6,ATG5,ISG15,IKBKE	0.179106867
REACTOME_RIG_I_MDA5_MEDIATED_INDUCTION_OF_IFN_ALPHA_BETA_PATHWAYS	TANK,CHUK,CREBBP,CYLD,AGER,EP300,DDX58,DAK,TBK1,UBE2K,HMGB1,IFNA1,IFNA2,IFNA4,IFNA5,IFNA6,IFNA7,IFNA8,IFNA10,IFNA14,IFNA16,IFNA17,IFNA21,IFNB1,APP,IKBKB,IRF1,IRF2,IRF3,IRF7,MAP3K1,NFKB2,NFKBIA,NFKBIB,PCBP2,HERC5,PIN1,RNF125,OTUD5,MAVS,RELA,RPS27A,S100A12,S100B,SAA1,IFIH1,TNFAIP3,TRAF2,TRAF3,TRAF6,RPS27AP11,UBA52,UBA7,UBE2D1,UBE2D2,UBE2D3,TRIM25,DHX58,NLRX1,SIKE1,CASP8,NLRC5,RNF135,CASP10,IKBKG,RIPK1,FADD,TAX1BP1,ATG12,UBE2L6,ATG5,ISG15,IKBKE	0.087594285
REACTOME_IKK_COMPLEX_RECRUITMENT_MEDIATED_BY_RIP1	CHUK,TICAM1,LY96,TICAM2,IKBKB,TLR3,TLR4,IKBKG,RIPK1,CD14	0.128403716
REACTOME_TRANSCRIPTIONAL_REGULATION_OF_WHITE_ADIPOCYTE_DIFFERENTIATION	MED6,MED16,CDK4,CDK8,NCOA2,CEBPB,CEBPD,PPARGC1A,MED8,CREBBP,EBF1,EGR2,EP300,FABP4,MED19,NCOA6,CDK19,MED13L,MED4,LEP,MED11,LPL,MED31,PCK1,ANGPTL4,MED15,PLIN1,PPARA,PPARG,MED1,MED18,MED9,MED29,RELA,RXRA,SLC2A4,SMARCD3,SREBF1,MED22,KLF5,TBL1X,NR2F2,TGFB1,TNF,WNT1,WNT10B,TBL1XR1,MED25,NCOA3,MED10,PRIC285,NCOA1,HDAC3,CCNC,CCND3,MED30,MED14,KLF4,ADIPOQ,MED21,MED23,MED17,MED26,MED27,MED7,MED20,CD36,NCOR1,NCOR2,TGS1,MED24,MED12	0.055431112
REACTOME_SIGNALING_BY_NOTCH	HDAC6,HDAC5,MAMLD1,ADAM10,CDK8,ST3GAL6,TMED2,DTX2,CNTN1,CREBBP,MIB2,JAG1,DTX1,E2F1,E2F3,EIF2C3,EIF2C4,EP300,SNW1,TNRC6B,DTX4,NCSTN,HEY1,HEY2,POFUT1,KAT2A,HEYL,EIF2C1,B4GALT1,EIF2C2,TNRC6A,DLL1,HDAC1,HDAC2,HIF1A,HES1,RBPJ,JAG2,JUN,HES5,LFNG,ARRB1,ARRB2,MFNG,MOV10,LOC441488,MYC,NOTCH2,NOTCH3,NOTCH4,ATP2A1,ATP2A2,ATP2A3,FURIN,APH1A,HDAC7,DLL4,FBXW7,MAML3,PSENEN,HDAC8,PSEN1,PSEN2,POGLUT1,MIB1,TNRC6C,RAB6A,CCND1,RFNG,RPS27A,SEL1L,ST3GAL3,SKP1,ADAM17,TBL1X,TFDP1,TLE1,TLE2,TLE3,TLE4,TP53,LOC728030,RPS27AP11,UBA52,TBL1XR1,HDAC11,APH1B,HDAC10,MAML2,CUL1,NUMB,DLK1,HDAC3,KAT2B,CCNC,NEURL,DNER,NCOR1,NCOR2,HDAC9,HDAC4,MAML1,RBX1	0.113425981
REACTOME_SYNTHESIS_OF_VERY_LONG_CHAIN_FATTY_ACYL_COAS	ACSL1,ACSL3,ACSL4,ACSL6,HSD17B12,ACSL5,ELOVL2,ELOVL5,ELOVL1,ELOVL4,ELOVL6,ELOVL7,ELOVL3,TECR	0.104882864
REACTOME_HORMONE_SENSITIVE_LIPASE_HSL_MEDIATED_TRIACYLGLYCEROL_HYDROLYSIS	MGLL,FABP4,LIPE,ABHD5,PLIN1,PPP1CA,PPP1CB,PPP1CC,PRKACA,PRKACB,PRKACG,LOC730418,CAV1	0.184973283
REACTOME_SIGNALING_BY_TGF_BETA_RECEPTOR_COMPLEX	CDK8,CDK9,STUB1,CDKN2B,STRAP,PARP1,E2F4,E2F5,FKBP1A,ARHGEF18,PPP1R15A,WWTR1,HDAC1,JUNB,RHOA,SMAD2,SMAD3,SMAD4,SMAD7,MEN1,LOC441488,MYC,FURIN,SERPINE1,F11R,PARD6A,UCHL5,TRIM33,PPM1A,PPP1CA,PPP1CB,PPP1CC,PRKCZ,PARD3,PMEPA1,SMURF1,CGN,RBL1,TGIF2,RPS27A,SMURF2,SKI,SKIL,SP1,TFDP1,TGFB1,TGFBR1,TGFBR2,TGIF1,RPS27AP11,UBA52,LOC731429,UBE2D1,UBE2D3,XPO1,USP9X,CCNC,CCNT1,CCNT2,MTMR4,ZFYVE9,NCOR1,NCOR2	0.072686212
REACTOME_COMPLEMENT_CASCADE	MASP2,CFHR3,CR1,CRP,CD55,CFD,CFH,CFI,MBL2,CD46,PROS1,MASP1,CFB,LOC651536,LOC653879,C1QA,C1QB,C1QC,C1S,C2,C3,C4A,C4BPA,C4BPB,C5,C6,C7,C8A,LOC731066,C8B,C8G,C9	0.146138578
REACTOME_VOLTAGE_GATED_POTASSIUM_CHANNELS	KCNH8,KCNV2,KCNG3,KCNH4,KCNH3,KCNG2,KCNV1,KCNH5,KCNA1,KCNA2,KCNA3,KCNA4,KCNA5,KCNA6,KCNA7,KCNA10,KCNB1,KCNC1,KCNC2,KCNC3,KCNC4,KCND1,KCND2,KCND3,KCNF1,KCNG1,KCNH1,KCNH2,KCNQ1,KCNQ2,KCNQ3,KCNS1,KCNS2,KCNS3,KCNQ5,KCNAB1,KCNH6,KCNAB2,KCNH7,KCNQ4,KCNAB3,KCNG4,KCNB2	0.112007038
REACTOME_NOD1_2_SIGNALING_PATHWAY	NOD1,TAB1,CHUK,MAPK14,CYLD,TAB2,TAB3,BIRC2,BIRC3,IKBKB,IRAK1,IRAK2,TMEM189-UBE2V1,MAPK11,MAPK13,MAP2K6,MAPK12,NOD2,CARD9,MAP3K7,TNFAIP3,TRAF6,UBE2N,CASP1,CASP2,CASP4,CASP8,CASP9,IKBKG,RIPK2	0.210584571
REACTOME_PIP3_ACTIVATES_AKT_SIGNALING	AKT3,CDKN1A,CDKN1B,CHUK,THEM4,CREB1,AKT1,AKT2,FOXO1,FOXO3,PHLPP1,MTOR,RICTOR,GSK3A,NR4A1,MDM2,FOXO4,PDPK1,BAD,PTEN,TRIB3,RPS6KB2,MLST8,TSC2,LOC729120,LOC731292,MAPKAP1,CASP9,AKT1S1	0.214852194
REACTOME_POTASSIUM_CHANNELS	HCN4,ABCC9,KCNK7,KCNMB2,KCNH8,KCNV2,KCNG3,KCNH4,KCNH3,GABBR1,KCNG2,KCNV1,KCNMB3,KCNH5,KCNMB4,GNB1,GNB2,GNB3,GNG3,GNG4,GNG5,GNG7,GNG10,GNGT1,GNGT2,KCNK18,HCN1,KCNA1,KCNA2,KCNA3,KCNA4,KCNA5,KCNA6,KCNA7,KCNA10,KCNB1,KCNC1,KCNC2,KCNC3,KCNC4,KCND1,KCND2,KCND3,KCNF1,KCNG1,KCNH1,KCNH2,KCNJ1,KCNJ2,KCNJ3,KCNJ4,KCNJ5,KCNJ6,KCNJ8,KCNJ9,KCNJ10,KCNJ11,KCNJ12,KCNJ14,KCNJ15,KCNJ16,KCNK1,KCNK2,KCNK3,KCNMB1,KCNN1,KCNN2,KCNN3,KCNN4,KCNQ1,KCNQ2,KCNQ3,KCNS1,KCNS2,KCNS3,KCNK4,KCNK9,KCNK10,GNG2,GNG12,KCNQ5,KCNK13,HCN3,HCN2,ABCC8,KCNAB1,KCNH6,KCNK16,KCNAB2,KCNK17,KCNH7,KCNQ4,KCNAB3,KCNG4,KCNB2,GNG8,KCNK6,GABBR2	0.030846038
REACTOME_INWARDLY_RECTIFYING_K_CHANNELS	ABCC9,GABBR1,GNB1,GNB2,GNB3,GNG3,GNG4,GNG5,GNG7,GNG10,GNGT1,GNGT2,KCNJ1,KCNJ2,KCNJ3,KCNJ4,KCNJ5,KCNJ6,KCNJ8,KCNJ9,KCNJ10,KCNJ11,KCNJ12,KCNJ14,KCNJ15,KCNJ16,GNG2,GNG12,ABCC8,GNG8,GABBR2	0.055391018
REACTOME_INITIAL_TRIGGERING_OF_COMPLEMENT	MASP2,CRP,CFD,MBL2,MASP1,CFB,LOC651536,LOC653879,C1QA,C1QB,C1QC,C1S,C2,C3,C4A,LOC731066	0.122186685
