Package: RTN
Type: Package
Title: RTN: Reconstruction of Transcriptional regulatory Networks and
        analysis of regulons
Version: 2.34.1
Author: Clarice Groeneveld [ctb], Gordon Robertson [ctb], Xin Wang
        [aut], Michael Fletcher [aut], Florian Markowetz [aut], Kerstin
        Meyer [aut], and Mauro Castro [aut]
Maintainer: Mauro Castro <mauro.a.castro@gmail.com>
Depends: R (>= 3.6.3), methods,
Imports: RedeR, minet, viper, mixtools, snow, stats, limma, data.table,
        IRanges, igraph, S4Vectors, SummarizedExperiment, car, pwr,
        pheatmap, grDevices, graphics, utils
Suggests: RUnit, BiocGenerics, BiocStyle, knitr, rmarkdown
Description: A transcriptional regulatory network (TRN) consists of a
        collection of transcription factors (TFs) and the regulated
        target genes. TFs are regulators that recognize specific DNA
        sequences and guide the expression of the genome, either
        activating or repressing the expression the target genes. The
        set of genes controlled by the same TF forms a regulon. This
        package provides classes and methods for the reconstruction of
        TRNs and analysis of regulons.
License: Artistic-2.0
biocViews: Transcription, Network, NetworkInference, NetworkEnrichment,
        GeneRegulation, GeneExpression, GraphAndNetwork,
        GeneSetEnrichment, GeneticVariability
VignetteBuilder: knitr
URL: http://dx.doi.org/10.1038/ncomms3464
Collate: ClassUnions.R AllChecks.R AllClasses.R AllGenerics.R
        AllSupplementsTNA.R AllSupplementsTNI.R AllSupplementsAVS.R
        AllPlotsTNA.R AllPlotsAVS.R AllPlotsTNI.R TNA-methods.R
        TNI-methods.R AVS-methods.R TNI-pruning.R TNI-annotation.R
        TNI-subgroups.R
LazyLoad: yes
Config/pak/sysreqs: cmake libglpk-dev make libicu-dev libxml2-dev
        libssl-dev zlib1g-dev
Repository: https://bioc-release.r-universe.dev
Date/Publication: 2026-02-25 14:17:00 UTC
RemoteUrl: https://github.com/bioc/RTN
RemoteRef: RELEASE_3_22
RemoteSha: 6f91683380c41b05d8274b1cfe32c10c293122d6
NeedsCompilation: no
Packaged: 2026-02-26 06:04:24 UTC; root
Built: R 4.5.2; ; 2026-02-26 06:12:13 UTC; unix
