Deep characterization of cancer drugs

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Documentation for package ‘DeepTarget’ version 1.1.0

• DESCRIPTION file.
• User guides, package vignettes and other documentation.
• Package NEWS.

Help Pages

computeCor	Compute a correlation between the every gene vs each drug response
Depmap2DeepTarget	Retrieval and preparation of input data required from Depmap to Deeptarget package.
DMB	Predicting Drug Mutant Binding for mutant or non-mutant form
DoInteractExp	Compute the interaction between the drug and KO expression
DoInteractMutant	Compute interaction between the drug and KO expression in term of mutant vs non-mutant
DoPWY	Provide a probability score for each pathway for the primary of mechanism of action (MOA) of a drug
DTR	Predicting Drug Target Response (DTR) for primary or secondary targets
OntargetM	An object containing a small part of the data from the Cancer Dependency Map (depmap.org) to demonstrate in DeepTarget pipeline
plotCor	Plot the correlation
plotSim	Plot the similarty between corelation values and P vals for all genes. The top 5 genes are labeled.
PredMaxSim	Predict the most similar gene to the drug response
PredTarget	Prediction of the most similar known targeted gene.