scoup

This is the released version of scoup; for the devel version, see scoup.

Simulate Codons with Darwinian Selection Modelled as an OU Process


Bioconductor version: Release (3.20)

An elaborate molecular evolutionary framework that facilitates straightforward simulation of codon genetic sequences subjected to different degrees and/or patterns of Darwinian selection. The model was built upon the fitness landscape paradigm of Sewall Wright, as popularised by the mutation-selection model of Halpern and Bruno. This enabled realistic evolutionary process of living organisms to be reproduced seamlessly. For example, an Ornstein-Uhlenbeck fitness update algorithm is incorporated herein. Consequently, otherwise complex biological processes, such as the effect of the interplay between genetic drift and mutation on the inference of diversifying selection, may now be investigated with minimal effort. Frequency-dependent and deterministic fitness landscape update techniques are also available.

Author: Hassan Sadiq [aut, cre, cph]

Maintainer: Hassan Sadiq <hassan.t.sadiq at gmail.com>

Citation (from within R, enter citation("scoup")):

Installation

To install this package, start R (version "4.4") and enter:


if (!require("BiocManager", quietly = TRUE))
    install.packages("BiocManager")

BiocManager::install("scoup")

For older versions of R, please refer to the appropriate Bioconductor release.

Documentation

To view documentation for the version of this package installed in your system, start R and enter:

browseVignettes("scoup")
scoup Tutorial HTML R Script
Reference Manual PDF
NEWS Text

Details

biocViews Alignment, Classification, ComparativeGenomics, DataImport, Genetics, MathematicalBiology, ResearchField, SequenceMatching, Sequencing, Software, StatisticalMethod, WorkflowStep
Version 1.0.0
In Bioconductor since BioC 3.20 (R-4.4) (< 6 months)
License GPL (>= 2)
Depends R (>= 4.4), Matrix
Imports Biostrings, methods
System Requirements
URL https://github.com/thsadiq/scoup
Bug Reports https://github.com/thsadiq/scoup/issues
See More
Suggests BiocManager, BiocStyle, bookdown, htmltools, knitr, testthat (>= 3.0.0), yaml
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Package Archives

Follow Installation instructions to use this package in your R session.

Source Package scoup_1.0.0.tar.gz
Windows Binary (x86_64) scoup_1.0.0.zip
macOS Binary (x86_64) scoup_1.0.0.tgz
macOS Binary (arm64) scoup_1.0.0.tgz
Source Repository git clone https://git.bioconductor.org/packages/scoup
Source Repository (Developer Access) git clone git@git.bioconductor.org:packages/scoup
Bioc Package Browser https://code.bioconductor.org/browse/scoup/
Package Short Url https://bioconductor.org/packages/scoup/
Package Downloads Report Download Stats