SpaNorm

This is the released version of SpaNorm; for the devel version, see SpaNorm.

Spatially-aware normalisation for spatial transcriptomics data


Bioconductor version: Release (3.20)

This package implements the spatially aware library size normalisation algorithm, SpaNorm. SpaNorm normalises out library size effects while retaining biology through the modelling of smooth functions for each effect. Normalisation is performed in a gene- and cell-/spot- specific manner, yielding library size adjusted data.

Author: Dharmesh D. Bhuva [aut, cre] , Agus Salim [aut] , Ahmed Mohamed [aut]

Maintainer: Dharmesh D. Bhuva <dharmesh.bhuva at adelaide.edu.au>

Citation (from within R, enter citation("SpaNorm")):

Installation

To install this package, start R (version "4.4") and enter:


if (!require("BiocManager", quietly = TRUE))
    install.packages("BiocManager")

BiocManager::install("SpaNorm")

For older versions of R, please refer to the appropriate Bioconductor release.

Documentation

To view documentation for the version of this package installed in your system, start R and enter:

browseVignettes("SpaNorm")
SpaNorm HTML R Script
Reference Manual PDF
NEWS Text

Details

biocViews CellBiology, GeneExpression, Software, Spatial, Transcriptomics
Version 1.0.0
In Bioconductor since BioC 3.20 (R-4.4) (< 6 months)
License GPL (>= 3)
Depends R (>= 4.4)
Imports edgeR, ggplot2, Matrix, matrixStats, methods, rlang, scran, SeuratObject, SingleCellExperiment, SpatialExperiment, stats, SummarizedExperiment, S4Vectors, utils
System Requirements
URL https://bhuvad.github.io/SpaNorm
Bug Reports https://github.com/bhuvad/SpaNorm/issues
See More
Suggests testthat (>= 3.0.0), knitr, rmarkdown, prettydoc, pkgdown, covr, BiocStyle, Seurat, patchwork, ggforce, ggnewscale
Linking To
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Package Archives

Follow Installation instructions to use this package in your R session.

Source Package SpaNorm_1.0.0.tar.gz
Windows Binary (x86_64) SpaNorm_1.0.0.zip
macOS Binary (x86_64) SpaNorm_1.0.0.tgz
macOS Binary (arm64) SpaNorm_1.0.0.tgz
Source Repository git clone https://git.bioconductor.org/packages/SpaNorm
Source Repository (Developer Access) git clone git@git.bioconductor.org:packages/SpaNorm
Bioc Package Browser https://code.bioconductor.org/browse/SpaNorm/
Package Short Url https://bioconductor.org/packages/SpaNorm/
Package Downloads Report Download Stats