Unified methods for the inference and analysis of gene regulatory networks


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Documentation for package ‘netZooR’ version 1.9.0

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adjMatToElist converts adjacency matrix to edge list
alpaca Main ALPACA function
alpacaCommunityStructureRotation Comparing node community membership between two networks
alpacaComputeDifferentialScoreFromDWBM Compute Differential modularity score from differential modularity matrix
alpacaComputeDWBMmatmScale Differential modularity matrix
alpacaComputeWBMmat Compute modularity matrix for weighted bipartite network
alpacaCrane Find the robust nodes in ALPACA community using CRANE
alpacaDeltaZAnalysis Edge subtraction method (CONDOR optimizaton)
alpacaDeltaZAnalysisLouvain Edge subtraction method (Louvain optimizaton)
alpacaExtractTopGenes Extract core target genes in differential modules
alpacaGenLouvain Generalized Louvain optimization
alpacaGetMember get the member vector from alpaca object
alpacaGOtabtogenes The top GO term associated genes in each module
alpacaGoToGenes Map GO terms to gene symbols
alpacaListToGo GO term enrichment for a list of gene sets
alpacaMetaNetwork Create alpacaMetaNetwork for Louvain optimization
alpacaNodeToGene Remove tags from gene names
alpacaObjectToDfList Converts alpaca output into list of data frames
alpacaRotationAnalysis Community comparison method (CONDOR optimizaton)
alpacaRotationAnalysisLouvain Community comparison method (CONDOR optimizaton)
alpacaSimulateNetwork Simulated networks
alpacaTestNodeRank Enrichment in ranked list
alpacaTidyConfig Renumbering community membership vector
alpacaTopEnsembltoTopSym Translating gene identifiers to gene symbols
alpacaWBMlouvain Generalized Louvain method for bipartite networks
condorCluster Main clustering function for condor.
condorCoreEnrich Compare qscore distribution of a subset of nodes to all other nodes.
condorCreateObject creates condor object
condorMatrixModularity Iteratively maximize bipartite modularity.
condorModularityMax Iteratively maximize bipartite modularity.
condorPlotCommunities Plot adjacency matrix with links grouped and colored by community
condorPlotHeatmap Plot weighted adjacency matrix with links grouped by community
condorQscore Calculate Qscore for all nodes
condorRun Run CONDOR clustering
craneBipartite Pertrubs the bipartite network with fixed node strength
craneUnipartite Pertrubs the unipartite network with fixed node strength from adjacency matrix
createCondorObject Create list amenable to analysis using 'condor' package.
createPandaStyle Create a Cytoscape visual style for PANDA network
degreeAdjust Function to adjust the degree so that the hub nodes are not penalized in z-score transformation
dragon Run DRAGON in R.
elistAddTags Adds "_A" to first column and "_B" to second column
elistIsEdgeOrderEqual check if first two columns are identical
elistRemoveTags undo elistAddTags
elistSort Sorts the edge list based on first two columns in alphabetical order
elistToAdjMat Converts edge list to adjacency matrix
exon.size Gene length
genes Example of a gene list
isElist Check if data frame is an edge list
jutterDegree CRANE Beta perturbation function. This function will add noice to the node strength sequence.
lioness Compute LIONESS (Linear Interpolation to Obtain Network Estimates for Single Samples)
lionessPy Run python implementation of LIONESS
monster MOdeling Network State Transitions from Expression and Regulatory data (MONSTER)
monsterBereFull Bipartite Edge Reconstruction from Expression data (composite method with direct/indirect)
monsterCalculateTmPValues Calculate p-values for a tranformation matrix
monsterCheckDataType Checks that data is something MONSTER can handle
monsterdTFIPlot This function plots the Off diagonal mass of an observed Transition Matrix compared to a set of null TMs
monsterGetTm monsterGetTm
monsterHclHeatmapPlot Transformation matrix plot
monsterMonsterNI Bipartite Edge Reconstruction from Expression data
monsterPlotMonsterAnalysis monsterPlotMonsterAnalysis
monsterPrintMonsterAnalysis monsterPrintMonsterAnalysis
monsterRes MONSTER results from example cell-cycle yeast transition
monsterTransformationMatrix Bi-partite network analysis tools
monsterTransitionNetworkPlot This function uses igraph to plot the transition matrix (directed graph) as a network. The edges in the network should be read as A 'positively/negatively contributes to' the targeting of B in the target state.
monsterTransitionPCAPlot Principal Components plot of transformation matrix
mut.ucec Example of mutation data
otter Run OTTER in R
pandaDiffEdges Identify differential edges in two PANDA networks
pandaPy Run Python implementation PANDA in R
pandaToAlpaca Use two PANDA network to generate an ALPACA result
pandaToCondorObject Turn PANDA network into a CONDOR object
runEgret Run EGRET in R
sambar Main SAMBAR function.
sambarConvertgmt Convert .gmt files into a binary matrix.
sambarCorgenelength Normalize gene mutation scores by gene length.
sambarDesparsify De-sparsify gene-level mutation scores into gene set-level mutation scores.
small1976 Pollinator-plant interactions
sourcePPI Source the Protein-Protein interaction in STRING database
spider Seeding PANDA Interactions to Derive Epigenetic Regulation
visPandaInCytoscape Plot PANDA network in Cytoscape
yeast Toy data derived from three gene expression datasets and a mapping from transcription factors to genes.