Deconvolution of mixed cells from spatial and/or bulk gene expression data


[Up] [Top]

Documentation for package ‘SpatialDecon’ version 1.16.0

Help Pages

SpatialDecon-package SpatialDecon: A package for estimating mixed cell type abundance in the regions of spatially-resolved gene expression studies
cellcols Default colors for the cell types in the safeTME matrix
collapseCellTypes Collapse related cell types within a deconvolution result
create_profile_matrix Create Custom Cell Profile Matrix
derive_GeoMx_background Derive background at the scale of the normalized data for GeoMx data
download_profile_matrix Download a cell profile matrix
florets Draw coxcomb plots as points in a graphics window
mean.resid.sd Genes' biological variability in immune deconvolution from TCGA.
mergeTumorIntoX Estimate a tumor-specific profile and merge it with the pre-specified cell profile matrix (X)
mini_geomx_dataset Small example GeoMx data
mini_singleCell_dataset Mini human colon single cell dataset
nsclc Large example GeoMx data
reverseDecon Reverse deconvolution
runCollapseCellTypes Run collapseCellTypes
runCollapseCellTypes-method Run collapseCellTypes
runErrorModel Apply error model to estimate technical SD from raw counts
runMergeTumorIntoX Run MergeTumorIntoX
runMergeTumorIntoX-method Run MergeTumorIntoX
runReverseDecon Run Reversedecon
runReverseDecon-method Run Reversedecon
runspatialdecon Run spatialdecon
runspatialdecon-method Run spatialdecon
safeTME SafeTME matrix
safeTME.matches Mapping from granularly-defined cell populations to broaded cell populations
spatialdecon Mixed cell deconvolution of spatiall-resolved gene expression data
TIL_barplot Barplot of abundance estimates