Functional analysis of DNA methylome datasets


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Documentation for package ‘knowYourCG’ version 1.1.0

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aggregateTestEnrichments Aggregate test enrichment results
annoProbes Annotate Probe IDs using KYCG databases
buildGeneDBs build gene-probe association database
dbStats dbStats aggregates methylation of a given betas matrix over specified database set features
getDBs Get databases by full or partial names of the database group(s)
listDBGroups List database group names
testEnrichment testEnrichment tests for the enrichment of a set of probes (query set) in a number of features (database sets).
testEnrichmentFisher testEnrichmentFisher uses Fisher's exact test to estimate the association between two categorical variables.
testEnrichmentSEA uses the GSEA-like test to estimate the association of a categorical variable against a continuous variable.
testEnrichmentSpearman testEnrichmentSpearman uses the Spearman statistical test to estimate the association between two continuous variables.
testGO tests Gene Ontology of genes overlapping CpG query
testProbeProximity testProbeProximity tests if a query set of probes share closer genomic proximity than if randomly distributed