Conditional Differential Analysis for Flow and Mass Cytometry Experiments


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Documentation for package ‘CytoGLMM’ version 1.13.0

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cytoflexmix Logistic mixture regression
cytoglm Fit GLM with bootstrap resampling
cytoglmm Fit GLMM with method of moments
cytogroup Group-specific fixed effects model
cytostab Evaluate parameter stability with respect to gating sheme
cyto_check Check if input to cytoxxx function have errors
generate_data Generate dataset for vignettes and simulation studies
glmm_moment Generalized linear mixed model with maximum likelihood
is_unpaired Check if samples match or paired on condition
plot.cytoflexmix Plot all components of mixture regression
plot.cytoglm Plot bootstraped coefficients
plot.cytoglmm Plot fixded coefficients of random effects model
plot.cytogroup Plot fixded coefficients of group-specific fixed effects model
plot_coeff Helper function to plot regression coeffcient
plot_heatmap Heatmap of median marker expression
plot_lda LDA on marker expression
plot_mds MDS on median marker expression
plot_model_selection Plot model selection to choose number optimal number of clusters
plot_prcomp Plot PCA of subsampled data using ggplot
print.cytoglm Extact and print bootstrap GLM fit
print.cytoglmm Extact and print GLMM fit
remove_samples Remove samples based on low cell counts
summary.cytoglm Extact and calculate p-values of bootstrap GLM fit
summary.cytoglmm Extact and calculate p-values of GLMM fit