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Accurate Inference of Genetic Ancestry from Cancer Sequences

Bioconductor version: Release (3.19)

This package implements specialized algorithms that enable genetic ancestry inference from various cancer sequences sources (RNA, Exome and Whole-Genome sequences). This package also implements a simulation algorithm that generates synthetic cancer-derived data. This code and analysis pipeline was designed and developed for the following publication: Belleau, P et al. Genetic Ancestry Inference from Cancer-Derived Molecular Data across Genomic and Transcriptomic Platforms. Cancer Res 1 January 2023; 83 (1): 49–58.

Author: Pascal Belleau [cre, aut] , Astrid Deschênes [aut] , David A. Tuveson [aut] , Alexander Krasnitz [aut]

Maintainer: Pascal Belleau <pascal_belleau at>

Citation (from within R, enter citation("RAIDS")):


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if (!require("BiocManager", quietly = TRUE))


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Accurate Inference of Genetic Ancestry from Cancer-derived Sequences HTML R Script
Population reference dataset GDS files HTML R Script
Reference Manual PDF


biocViews DimensionReduction, GeneticVariability, Genetics, PrincipalComponent, Sequencing, Software, WholeGenome
Version 1.2.0
In Bioconductor since BioC 3.18 (R-4.3) (0.5 years)
License Apache License (>= 2)
Depends R (>= 4.2.0), gdsfmt, SNPRelate, stats, utils, GENESIS
Imports S4Vectors, GenomicRanges, ensembldb, BSgenome, AnnotationDbi, methods, class, pROC, IRanges, AnnotationFilter, rlang, VariantAnnotation, MatrixGenerics
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Suggests testthat, knitr, rmarkdown, BiocStyle, withr, GenomeInfoDb, BSgenome.Hsapiens.UCSC.hg38, EnsDb.Hsapiens.v86
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