MSstatsPTM
Statistical Characterization of Post-translational Modifications
Bioconductor version: Release (3.19)
MSstatsPTM provides general statistical methods for quantitative characterization of post-translational modifications (PTMs). Supports DDA, DIA, SRM, and tandem mass tag (TMT) labeling. Typically, the analysis involves the quantification of PTM sites (i.e., modified residues) and their corresponding proteins, as well as the integration of the quantification results. MSstatsPTM provides functions for summarization, estimation of PTM site abundance, and detection of changes in PTMs across experimental conditions.
Author: Devon Kohler [aut, cre], Tsung-Heng Tsai [aut], Ting Huang [aut], Mateusz Staniak [aut], Meena Choi [aut], Olga Vitek [aut]
Maintainer: Devon Kohler <kohler.d at northeastern.edu>
citation("MSstatsPTM")):
Installation
To install this package, start R (version "4.4") and enter:
if (!require("BiocManager", quietly = TRUE))
install.packages("BiocManager")
BiocManager::install("MSstatsPTM")
For older versions of R, please refer to the appropriate Bioconductor release.
Documentation
To view documentation for the version of this package installed in your system, start R and enter:
browseVignettes("MSstatsPTM")| MSstatsPTM LabelFree Workflow | HTML | R Script |
| MSstatsPTM TMT Workflow | HTML | R Script |
| Reference Manual |
Details
| biocViews | DifferentialExpression, ImmunoOncology, MassSpectrometry, Normalization, OneChannel, Proteomics, QualityControl, Software, TwoChannel |
| Version | 2.6.1 |
| In Bioconductor since | BioC 3.12 (R-4.0) (4 years) |
| License | Artistic-2.0 |
| Depends | R (>= 4.3) |
| Imports | dplyr, gridExtra, stringr, stats, ggplot2, stringi, grDevices, MSstatsTMT, MSstatsConvert, MSstats, data.table, Rcpp, Biostrings, checkmate, ggrepel |
| System Requirements | |
| URL | |
| Bug Reports | https://github.com/Vitek-Lab/MSstatsPTM/issues |
See More
| Suggests | knitr, rmarkdown, tinytest, covr, mockery, testthat (>= 3.0.0) |
| Linking To | Rcpp |
| Enhances | |
| Depends On Me | |
| Imports Me | MSstatsLiP, MSstatsShiny |
| Suggests Me | |
| Links To Me | |
| Build Report | Build Report |
Package Archives
Follow Installation instructions to use this package in your R session.
| Source Package | MSstatsPTM_2.6.1.tar.gz |
| Windows Binary (x86_64) | MSstatsPTM_2.6.1.zip |
| macOS Binary (x86_64) | MSstatsPTM_2.6.1.tgz |
| macOS Binary (arm64) | MSstatsPTM_2.6.1.tgz |
| Source Repository | git clone https://git.bioconductor.org/packages/MSstatsPTM |
| Source Repository (Developer Access) | git clone git@git.bioconductor.org:packages/MSstatsPTM |
| Bioc Package Browser | https://code.bioconductor.org/browse/MSstatsPTM/ |
| Package Short Url | https://bioconductor.org/packages/MSstatsPTM/ |
| Package Downloads Report | Download Stats |
| Old Source Packages for BioC 3.19 | Source Archive |