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HybridMTest

Hybrid Multiple Testing


Bioconductor version: Release (3.19)

Performs hybrid multiple testing that incorporates method selection and assumption evaluations into the analysis using empirical Bayes probability (EBP) estimates obtained by Grenander density estimation. For instance, for 3-group comparison analysis, Hybrid Multiple testing considers EBPs as weighted EBPs between F-test and H-test with EBPs from Shapiro Wilk test of normality as weigth. Instead of just using EBPs from F-test only or using H-test only, this methodology combines both types of EBPs through EBPs from Shapiro Wilk test of normality. This methodology uses then the law of total EBPs.

Author: Stan Pounds <stanley.pounds at stjude.org>, Demba Fofana <demba.fofana at stjude.org>

Maintainer: Demba Fofana <demba.fofana at stjude.org>

Citation (from within R, enter citation("HybridMTest")):

Installation

To install this package, start R (version "4.4") and enter:


if (!require("BiocManager", quietly = TRUE))
    install.packages("BiocManager")

BiocManager::install("HybridMTest")

For older versions of R, please refer to the appropriate Bioconductor release.

Documentation

To view documentation for the version of this package installed in your system, start R and enter:

browseVignettes("HybridMTest")
Hybrid Multiple Testing PDF R Script
Reference Manual PDF

Details

biocViews GeneExpression, Genetics, Microarray, Software
Version 1.48.0
In Bioconductor since BioC 2.10 (R-2.15) (12 years)
License GPL Version 2 or later
Depends R (>= 2.9.0), Biobase, fdrtool, MASS, survival
Imports stats
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Package Archives

Follow Installation instructions to use this package in your R session.

Source Package HybridMTest_1.48.0.tar.gz
Windows Binary HybridMTest_1.48.0.zip (64-bit only)
macOS Binary (x86_64) HybridMTest_1.48.0.tgz
macOS Binary (arm64) HybridMTest_1.48.0.tgz
Source Repository git clone https://git.bioconductor.org/packages/HybridMTest
Source Repository (Developer Access) git clone git@git.bioconductor.org:packages/HybridMTest
Bioc Package Browser https://code.bioconductor.org/browse/HybridMTest/
Package Short Url https://bioconductor.org/packages/HybridMTest/
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