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This package is deprecated. It will probably be removed from Bioconductor. Please refer to the package end-of-life guidelines for more information.

An R interface for computational modeling of tumor progression

Bioconductor version: Release (3.19)

The CancerInSilico package provides an R interface for running mathematical models of tumor progresson and generating gene expression data from the results. This package has the underlying models implemented in C++ and the output and analysis features implemented in R.

Author: Thomas D. Sherman, Raymond Cheng, Elana J. Fertig

Maintainer: Thomas D. Sherman <tomsherman159 at>, Elana J. Fertig <ejfertig at>

Citation (from within R, enter citation("CancerInSilico")):


To install this package, start R (version "4.4") and enter:

if (!require("BiocManager", quietly = TRUE))


For older versions of R, please refer to the appropriate Bioconductor release.


Reference Manual PDF


biocViews BiomedicalInformatics, CellBiology, GeneExpression, ImmunoOncology, MathematicalBiology, RNASeq, SingleCell, Software, SystemsBiology
Version 2.24.0
In Bioconductor since BioC 3.4 (R-3.3) (7.5 years)
License GPL-2
Depends R (>= 3.4), Rcpp
Imports methods, utils, graphics, stats
System Requirements
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Suggests testthat, knitr, rmarkdown, BiocStyle, Rtsne, viridis, rgl, gplots
Linking To Rcpp, BH
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Follow Installation instructions to use this package in your R session.

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