A unified framework of realistic in silico data generation and statistical model inference for single-cell and spatial omics


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Documentation for package ‘scDesign3’ version 1.2.0

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ba Functions from gamlss/gamlss.add with bugs fixed
construct_data Construct the input data (covaraite matrix and expression matrix)
example_sce A SingelCellExperiment object containing both cell type and pseudotime
extract_para Extract the parameters of each cell's distribution
fit_copula Fit the copula model
fit_marginal Fit the marginal models
ga Functions from gamlss/gamlss.add with bugs fixed
gamlss.ba Support for Function ba()
gamlss.ga Support for Function ga()
perform_lrt Perform the likelihood ratio test
plot_reduceddim Dimensionality reduction and visualization
scdesign3 The wrapper for the whole scDesign3 pipeline
simu_new Simulate new data
sparse_cov This function computes the thresholding sparse covariance/correlation estimator with the optimal threshold level.