On-Target and Off-Target Scoring Algorithms for CRISPR gRNAs

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Documentation for package ‘crisprScore’ version 1.8.0

• DESCRIPTION file.
• User guides, package vignettes and other documentation.
• Package NEWS.

Help Pages

getAzimuthScores	Calculate on-target sgRNA activity scores for Cas9 using Azimuth
getCasRxRFScores	Calculate on-target sgRNA activity scores for CasRx using CasRx-RF
getCFDScores	Calculate CFD off-target specificity scores
getCrispraiScores	Calculate on-target sgRNA activity scores for CRISPRa and CRISPRi
getCRISPRaterScores	Calculate on-target sgRNA activity scores for Cas9 using CRISPRater
getCRISPRscanScores	Calculate on-target sgRNA activity scores for Cas9 using CRISPRscan
getDeepCpf1Scores	Calculate on-target sgRNA activity scores for Cas12a using DeepCpf1
getDeepHFScores	Calculate on-target sgRNA activity scores for Cas9 using DeepHF
getDeepSpCas9Scores	Calculate on-target sgRNA activity scores for SpCas9 using DeepSpCas9
getEnPAMGBScores	Calculate on-target sgRNA activity scores for enCas12a using enPAM+GB
getLindelScores	Predict frameshift ratios from CRISPR/Cas9 indel prediction using Lindel
getMITScores	Calculate MIT off-target specificity scores for CRISPR/Cas9
getRuleSet1Scores	Calculate on-target sgRNA activity scores for Cas9 using Rule Set 1
getRuleSet3Scores	Calculate on-target sgRNA activity scores for SpCas9 using Rule Set 3
scoringMethodsInfo	data.frame detailing available scoring methods
sgrnaExampleCrispra	Example CRISPRa gRNAs data.frame for the getCrispraiScores function
sgrnaExampleCrispri	Example CRISPRi gRNAs data.frame for the getCrispraiScores function
tssExampleCrispra	Example TSS data.frame for the getCrispraiScores function
tssExampleCrispri	Example TSS data.frame for the getCrispraiScores function