Integrates DNA methylation data with gene expression in a single gene network


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Documentation for package ‘iNETgrate’ version 1.0.0

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iNETgrate-package Integrates DNA methylation data with gene expression in a single gene network
accelFailAnalysis Accelerated Failure Analysis
analyzeSurvival Survival analysis
bestInetgrator Identifies the bestInetgrator
cleanAllData Cleans and preprocesses data
computEigengenes Compute eigengenes of combined modules.
computEigengloci rename Compute eigengenes of combined modules.
computEigenloci Computes an eigenloci for each gene
computeInetgrator Computes an inetgrator
computeUnion Computes union gene set
coxAnalysis Cox analysis
createLocusGene Mapping one locus to one gene.
distanceToTss Computes distance of loci to the closest TSS
downloaData Download and save TCGA data
electGenes Selects input genes for iNETgrate analysis.
filterLowCor Filters out genes or loci
findAliveCutoff Find Alive Cutoff
findCore Finds the most connected cluster of points
findTcgaDuplicates Identify and remove duplicate samples
iNETgrate iNETgrate - Runs entire iNETgrate pipeline.
inferEigengenes Infers features for the test(validation) dataset
makeNetwork Make network
plotKM Survival (Kaplan-Meier estimator) plots
plotLociNum Plot number of loci per gene.
plotLociTss Plots distance of loci to genes
prepareSurvival Prepare survival data
preprocessDnam Cleans DNA methylation data
sample2pat Maps sample IDs to corresponding patient IDs
sampleData Sample Data
toyCleanedAml A subset of cleaned TCGA-LAML data
toyComputEloci A subset of weighted DNA methylation profile of TCGA-LAML data
toyEigengenes A subset of weighted average of gene expression present in each module
toyRawAml A subset of TCGA-LAML data