DOI: 10.18129/B9.bioc.hapFabia  

This package is for version 3.17 of Bioconductor; for the stable, up-to-date release version, see hapFabia.

hapFabia: Identification of very short segments of identity by descent (IBD) characterized by rare variants in large sequencing data

Bioconductor version: 3.17

A package to identify very short IBD segments in large sequencing data by FABIA biclustering. Two haplotypes are identical by descent (IBD) if they share a segment that both inherited from a common ancestor. Current IBD methods reliably detect long IBD segments because many minor alleles in the segment are concordant between the two haplotypes. However, many cohort studies contain unrelated individuals which share only short IBD segments. This package provides software to identify short IBD segments in sequencing data. Knowledge of short IBD segments are relevant for phasing of genotyping data, association studies, and for population genetics, where they shed light on the evolutionary history of humans. The package supports VCF formats, is based on sparse matrix operations, and provides visualization of haplotype clusters in different formats.

Author: Sepp Hochreiter <hochreit at bioinf.jku.at>

Maintainer: Andreas Mitterecker <mitterecker at bioinf.jku.at>

Citation (from within R, enter citation("hapFabia")):


To install this package, start R (version "4.3") and enter:

if (!require("BiocManager", quietly = TRUE))


For older versions of R, please refer to the appropriate Bioconductor release.


To view documentation for the version of this package installed in your system, start R and enter:



PDF R Script hapFabia: Manual for the R package
PDF   Reference Manual
Text   NEWS


biocViews Clustering, GeneticVariability, Genetics, SNP, SequenceMatching, Sequencing, Software, Visualization
Version 1.42.0
In Bioconductor since BioC 2.11 (R-2.15) (11 years)
License LGPL (>= 2.1)
Depends R (>= 3.6.0), Biobase, fabia(>= 2.3.1)
Imports methods, graphics, grDevices, stats, utils
URL http://www.bioinf.jku.at/software/hapFabia/hapFabia.html
Depends On Me
Imports Me
Suggests Me
Links To Me
Build Report  

Package Archives

Follow Installation instructions to use this package in your R session.

Source Package hapFabia_1.42.0.tar.gz
Windows Binary hapFabia_1.42.0.zip (64-bit only)
macOS Binary (x86_64) hapFabia_1.42.0.tgz
macOS Binary (arm64) hapFabia_1.42.0.tgz
Source Repository git clone https://git.bioconductor.org/packages/hapFabia
Source Repository (Developer Access) git clone git@git.bioconductor.org:packages/hapFabia
Bioc Package Browser https://code.bioconductor.org/browse/hapFabia/
Package Short Url https://bioconductor.org/packages/hapFabia/
Package Downloads Report Download Stats

Documentation »


R / CRAN packages and documentation

Support »

Please read the posting guide. Post questions about Bioconductor to one of the following locations: