DOI: 10.18129/B9.bioc.CNAnorm  

This package is for version 3.17 of Bioconductor; for the stable, up-to-date release version, see CNAnorm.

A normalization method for Copy Number Aberration in cancer samples

Bioconductor version: 3.17

Performs ratio, GC content correction and normalization of data obtained using low coverage (one read every 100-10,000 bp) high troughput sequencing. It performs a "discrete" normalization looking for the ploidy of the genome. It will also provide tumour content if at least two ploidy states can be found.

Author: Stefano Berri <sberri at>, Henry M. Wood <H.M.Wood at>, Arief Gusnanto <a.gusnanto at>

Maintainer: Stefano Berri <sberri at>

Citation (from within R, enter citation("CNAnorm")):


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biocViews CopyNumberVariation, Coverage, DNASeq, GenomicVariation, Normalization, Sequencing, Software, WholeGenome
Version 1.46.1
In Bioconductor since BioC 2.9 (R-2.14) (12 years)
License GPL-2
Depends R (>= 2.10.1), methods
Imports DNAcopy
Depends On Me
Imports Me
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