Differential cell type change analysis using Logistic/linear Regression


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Documentation for package ‘LRcell’ version 1.8.0

Help Pages

enrich_posfrac_score Calculate enrichment scores for each cell type in a specific gene.
example_gene_pvals Example gene_pvals named vector from mouse experiment.
example_LRcell_res An example output of LRcell using data example_gene_pvals and mouse_FC_marker_genes.
get_markergenes Get top marker genes for each subcluster
LRcell Cell-type enrichment analysis for preranked gene set.
LRcellCore Find most enriched cell types in bulk DE genes by Logistic Regression
LRcell_gene_enriched_scores Find most enriched cell types in bulk DE genes by Logistic Regression
mouse_celltypes Mapping between subclusters and cell types in Mouse Brain
mouse_FC_marker_genes Example marker genes from mouse FC brain region.
plot_manhattan_enrich Manhattan plot for the enrichment of cell types
plot_marker_dist Plot marker genes distribution on DE gene rank