DOI: 10.18129/B9.bioc.splatter  

This package is for version 3.16 of Bioconductor; for the stable, up-to-date release version, see splatter.

Simple Simulation of Single-cell RNA Sequencing Data

Bioconductor version: 3.16

Splatter is a package for the simulation of single-cell RNA sequencing count data. It provides a simple interface for creating complex simulations that are reproducible and well-documented. Parameters can be estimated from real data and functions are provided for comparing real and simulated datasets.

Author: Luke Zappia [aut, cre] , Belinda Phipson [aut] , Christina Azodi [ctb] , Alicia Oshlack [aut]

Maintainer: Luke Zappia <luke at lazappi.id.au>

Citation (from within R, enter citation("splatter")):


To install this package, start R (version "4.2") and enter:

if (!require("BiocManager", quietly = TRUE))


For older versions of R, please refer to the appropriate Bioconductor release.


To view documentation for the version of this package installed in your system, start R and enter:



HTML R Script An introduction to the Splatter package
HTML R Script Splat simulation parameters
HTML R Script splatPop simulation
PDF   Reference Manual
Text   NEWS


biocViews GeneExpression, ImmunoOncology, RNASeq, Sequencing, SingleCell, Software, Transcriptomics
Version 1.22.1
In Bioconductor since BioC 3.5 (R-3.4) (6 years)
License GPL-3 + file LICENSE
Depends R (>= 4.0), SingleCellExperiment
Imports BiocGenerics, BiocParallel, checkmate (>= 2.0.0), edgeR, fitdistrplus, ggplot2, locfit, matrixStats, methods, scales, scater(>= 1.15.16), stats, SummarizedExperiment, utils, crayon, S4Vectors, grDevices
Suggests BiocStyle, covr, cowplot, magick, knitr, limSolve, lme4, progress, pscl, testthat, preprocessCore, rmarkdown, scDD, scran, mfa, phenopath, BASiCS(>= 1.7.10), zinbwave, SparseDC, BiocManager, spelling, igraph, scuttle, BiocSingular, VariantAnnotation, Biostrings, GenomeInfoDb, GenomicRanges, IRanges
URL https://github.com/Oshlack/splatter
BugReports https://github.com/Oshlack/splatter/issues
Depends On Me
Imports Me SCRIP
Suggests Me NewWave, scone, scPCA, SummarizedBenchmark
Links To Me
Build Report  

Package Archives

Follow Installation instructions to use this package in your R session.

Source Package splatter_1.22.1.tar.gz
Windows Binary splatter_1.22.1.zip
macOS Binary (x86_64) splatter_1.22.1.tgz
macOS Binary (arm64) splatter_1.22.1.tgz
Source Repository git clone https://git.bioconductor.org/packages/splatter
Source Repository (Developer Access) git clone git@git.bioconductor.org:packages/splatter
Bioc Package Browser https://code.bioconductor.org/browse/splatter/
Package Short Url https://bioconductor.org/packages/splatter/
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