Identification and Annotation of Protein Hotspot Residues

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Documentation for package ‘DominoEffect’ version 1.18.0

• DESCRIPTION file.
• User guides, package vignettes and other documentation.
• Package NEWS.

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align_to_unip	Align protein segnent around the hotspot to the UniProt/Swiss-Prot KB sequence.
calculate_boundary	calculate_boundary
DominoData	Sample data
DominoEffect	Identification of significant mutation hotspot residues.
GPo_of_hotspots	Converts hotspot mutation table into a GPo object
identify_hotspots	Identify hotspots
import_txdb	Imports txdb data and converts it into format required for DominoEffect package
map_to_func_elem	Functional annotation of significant hotspot residues.
SnpData	Sample data
TestData	Sample data