Performing meta-analyses of microbiome studies with MMUPHin
10/09/2019
Package
MMUPHin 1.10.0
1 Introduction
MMUPHin is an R package implementing meta-analysis methods for microbial
community profiles. It has interfaces for: a) covariate-controlled batch and
study effect adjustment, b) meta-analytic differential abundance testing, and meta-analytic discovery of c) discrete (cluster-based) or d) continuous
unsupervised population structure.
Overall, MMUPHin enables the normalization and combination of multiple
microbial community studies. It can then help in identifying microbes, genes,
or pathways that are differential with respect to combined phenotypes. Finally,
it can find clusters or gradients of sample types that reproduce consistently
among studies.
2 Installation
MMUPHin is a Bioconductor package and can be installed via the following command.
if (!requireNamespace("BiocManager", quietly = TRUE))
install.packages("BiocManager")
BiocManager::install("MMUPHin")This vignette is intended to provide working examples for all four
functionalities of MMUPHin.
MMUPHin can be loaded into R with the first library() command shown below. We also load some utility packages for data manipulation and visualization.
library(MMUPHin)
library(magrittr)
library(dplyr)
library(ggplot2)3 Input data
As input, MMUPHin requires a properly
formatted collection of microbial community studies, with both feature
abundances and accompanying metadata. Here we use the five published
colorectal cancer (CRC)
stool metagenomic studies, incorporated in Thomas et al. (2019).
Data for the studies are already
conveniently packaged and accessible through the Biocondcutor package
curatedMetagenomicData,
though additional wranglings are needed to format input for MMUPHin.
Importantly, MMUPHin asks that feature abundances be provided as a
feature-by-sample matrix, and the metadata be provided as a data frame.
The two objects shoud agree on sample IDs, that is, rowname of the feature
abundance matrix and colname of the metadata data frame must agree.
Many popular ’omic data classes in R already enforce this standard, such as
ExpressionSet from Biobase, or phyloseq from
phyloseq.
To minimize users’ efforts in loading data to run the examples, we have properly formatted the five studies for easy access. The feature abundances and metadata can be loaded with the following code chunk. For the interested user, the commented out scripts were used for accessing data directly from curatedMetagenomicData and formatting. It might be worthwhile to read through these as they perform many of the common tasks for preprocessing microbial feature abundance data in R, including sample/feature subsetting, normalization, filtering, etc.
data("CRC_abd", "CRC_meta")
CRC_abd[1:5, 1, drop = FALSE]## FengQ_2015.metaphlan_bugs_list.stool:SID31004
## s__Faecalibacterium_prausnitzii 0.11110668
## s__Streptococcus_salivarius 0.09660736
## s__Ruminococcus_sp_5_1_39BFAA 0.09115385
## s__Subdoligranulum_unclassified 0.05806767
## s__Bacteroides_stercoris 0.05685503CRC_meta[1, 1:5]## subjectID body_site
## FengQ_2015.metaphlan_bugs_list.stool:SID31004 SID31004 stool
## study_condition
## FengQ_2015.metaphlan_bugs_list.stool:SID31004 CRC
## disease
## FengQ_2015.metaphlan_bugs_list.stool:SID31004 CRC;fatty_liver;hypertension
## age_category
## FengQ_2015.metaphlan_bugs_list.stool:SID31004 adulttable(CRC_meta$studyID)##
## FengQ_2015.metaphlan_bugs_list.stool
## 107
## HanniganGD_2017.metaphlan_bugs_list.stool
## 55
## VogtmannE_2016.metaphlan_bugs_list.stool
## 104
## YuJ_2015.metaphlan_bugs_list.stool
## 128
## ZellerG_2014.metaphlan_bugs_list.stool
## 1574 Performing batch (study) effect adjustment with adjust_batch
adjust_batch aims to correct for technical study/batch effects in microbial
feature abundances. It takes as input the feature-by-sample abundance matrix,
and performs batch effect adjustment given provided batch and optional covariate variables. It returns the batch-adjusted abundance matrix. Check help(adjust_batch) for additional details and options. This figure from the paper (figure 2b) shows the desired effect of the batch adjustment: batch effects are removed, making the effect of the biological variable of interest easier to detect.
Here we use adjust_batch to correct for differences in the five studies,
while controlling for the effect of CRC versus control (variable
study_condition in CRC_meta).
adjust_batch returns a list of multiple outputs. The part we are most interested in now is the adjusted abundance table, which we assign to CRC_abd_adj.
fit_adjust_batch <- adjust_batch(feature_abd = CRC_abd,
batch = "studyID",
covariates = "study_condition",
data = CRC_meta,
control = list(verbose = FALSE))
CRC_abd_adj <- fit_adjust_batch$feature_abd_adjOne way to evaluate the effect of batch adjustment is to assess the total
variability in microbial profiles attributable to study differences, before
and after adjustment. This is commonly known as a PERMANOVA test
(Tang, Chen, and Alekseyenko 2016), and can be performed with the adonis function in
vegan. The inputs to adonis() are indices of microbial compositional dissimilarity.
library(vegan, quietly = TRUE)## This is vegan 2.6-2D_before <- vegdist(t(CRC_abd))
D_after <- vegdist(t(CRC_abd_adj))
set.seed(1)
fit_adonis_before <- adonis(D_before ~ studyID, data = CRC_meta)## 'adonis' will be deprecated: use 'adonis2' insteadfit_adonis_after <- adonis(D_after ~ studyID, data = CRC_meta)## 'adonis' will be deprecated: use 'adonis2' insteadprint(fit_adonis_before)## $aov.tab
## Permutation: free
## Number of permutations: 999
##
## Terms added sequentially (first to last)
##
## Df SumsOfSqs MeanSqs F.Model R2 Pr(>F)
## studyID 4 13.36 3.3400 11.855 0.07991 0.001 ***
## Residuals 546 153.82 0.2817 0.92009
## Total 550 167.18 1.00000
## ---
## Signif. codes: 0 '***' 0.001 '**' 0.01 '*' 0.05 '.' 0.1 ' ' 1
##
## $call
## adonis(formula = D_before ~ studyID, data = CRC_meta)
##
## $coefficients
## NULL
##
## $coef.sites
## [,1] [,2] [,3] [,4] [,5]
## (Intercept) 0.73079021 0.73169710 0.67250197 0.71605766 0.87336982
## studyID1 -0.04650105 -0.05934101 -0.06594520 -0.06916387 -0.04021647
## studyID2 -0.00960596 -0.01371390 -0.03127853 -0.04307342 -0.03532331
## studyID3 0.02492831 0.04299113 0.04968915 0.05007428 0.03897483
## studyID4 0.04102015 0.05598628 0.06354195 0.05829726 0.01373265
## [,6] [,7] [,8] [,9] [,10]
## (Intercept) 0.81329886 0.81982224 0.73286735 0.78795958 0.718324115
## studyID1 -0.06606706 -0.06650828 -0.06564355 -0.02205305 -0.046024930
## studyID2 -0.08502468 -0.03441529 -0.02623755 0.01814369 -0.003884227
## studyID3 0.06316730 0.05626508 0.05089622 -0.01825356 0.030691234
## studyID4 0.06503457 0.01587392 0.05786061 0.04961928 0.042904667
## [,11] [,12] [,13] [,14] [,15]
## (Intercept) 0.80541742 0.74132526 0.81710867 0.70795368 0.721987895
## studyID1 -0.04460555 -0.06188606 -0.07769478 -0.06250423 -0.068106124
## studyID2 0.01220036 0.01875803 -0.05734103 -0.02216895 -0.006623936
## studyID3 0.01853294 0.04324277 0.06442456 0.04787200 0.054217648
## studyID4 0.03508235 0.02154179 0.05558636 0.05359530 0.046021767
## [,16] [,17] [,18] [,19] [,20]
## (Intercept) 0.724763708 0.720709017 0.672344562 0.71879976 0.895069059
## studyID1 -0.041082155 -0.035945836 -0.018436077 -0.06847191 -0.026249117
## studyID2 0.020627539 0.029309877 0.026937828 -0.03286930 -0.008244704
## studyID3 0.009723736 -0.001863847 -0.007697855 0.05935282 0.019125882
## studyID4 0.046894057 0.040465859 0.039474956 0.05279717 0.015141685
## [,21] [,22] [,23] [,24] [,25]
## (Intercept) 0.70756159 0.859500463 0.73328228 0.87519251 0.78299716
## studyID1 -0.05207004 -0.040599238 -0.05130487 -0.06684140 -0.05570987
## studyID2 -0.03011202 -0.007236002 -0.05926688 -0.08763684 -0.08594157
## studyID3 0.02522928 0.036264028 0.05736280 0.06364694 0.07279483
## studyID4 0.06258455 -0.006517003 0.06319105 0.05981534 0.05848022
## [,26] [,27] [,28] [,29] [,30]
## (Intercept) 0.771194232 0.8417765012 0.708021213 0.74377429 0.80849317
## studyID1 -0.017877210 -0.0106373488 -0.056646978 -0.07045906 -0.06066943
## studyID2 0.006939035 0.0001720459 -0.008973142 -0.02893134 -0.05444733
## studyID3 0.008722146 -0.0009377920 0.037542927 0.06679191 0.06578068
## studyID4 0.010417212 0.0079291615 0.055077315 0.05305715 0.02607388
## [,31] [,32] [,33] [,34] [,35]
## (Intercept) 0.71096718 0.69937360 0.76646105 0.74107280 0.86080198
## studyID1 -0.08845056 -0.03262021 -0.07528971 -0.07232102 -0.07844225
## studyID2 -0.04830991 -0.03166673 -0.05595873 -0.07686114 -0.06609542
## studyID3 0.07345477 0.02174366 0.08403542 0.05670457 0.07321199
## studyID4 0.07208015 0.05820521 0.04970911 0.08259909 0.04108775
## [,36] [,37] [,38] [,39] [,40]
## (Intercept) 0.78485725 0.800353766 0.704317814 0.92518344 0.83096071
## studyID1 -0.07333451 -0.056877041 -0.059797497 -0.03717469 -0.09603239
## studyID2 -0.05788121 0.002084871 -0.002982447 -0.05980681 -0.06391249
## studyID3 0.07346187 0.046572844 0.032124676 0.03932895 0.08549132
## studyID4 0.04363908 0.035348179 0.042422987 0.02967674 0.04152928
## [,41] [,42] [,43] [,44] [,45]
## (Intercept) 0.86297220 0.72008343 0.7313460116 0.71515575 0.79402504
## studyID1 -0.02388482 -0.07173788 -0.0551093488 -0.07667420 -0.07120255
## studyID2 -0.01261734 -0.02623695 0.0003176773 -0.04030231 -0.07345587
## studyID3 0.02123076 0.05185719 0.0302679496 0.05886874 0.08452398
## studyID4 0.01485437 0.04856036 0.0486806985 0.07236564 0.04980713
## [,46] [,47] [,48] [,49] [,50]
## (Intercept) 0.79260432 0.726271016 0.83968414 0.73822097 0.76117565
## studyID1 -0.02275113 -0.018876038 -0.08818953 -0.09150021 -0.06949635
## studyID2 -0.02336605 0.033852323 -0.06934655 -0.06016353 -0.03795612
## studyID3 0.02077102 -0.003122252 0.07774874 0.08960851 0.05308874
## studyID4 0.03842737 0.007322358 0.04505643 0.05939020 0.05746601
## [,51] [,52] [,53] [,54] [,55]
## (Intercept) 0.749070788 0.72697936 0.70576051 0.731044308 0.71943910
## studyID1 -0.063512440 0.01976501 -0.03196234 -0.021915063 0.01711574
## studyID2 -0.007770849 0.08188655 0.03553587 0.057838550 0.07046869
## studyID3 0.051363240 -0.07090027 -0.01059085 -0.004548161 -0.06218881
## studyID4 0.036364110 0.01847215 0.04447515 0.004757544 0.02044711
## [,56] [,57] [,58] [,59] [,60]
## (Intercept) 0.694065903 0.81303818 0.772502057 0.73428510 0.768794266
## studyID1 0.005234712 -0.06509352 -0.005494334 -0.05623724 0.004823975
## studyID2 0.053840632 -0.02093313 0.057817276 0.01775326 0.060426824
## studyID3 -0.043458657 0.05468430 -0.016655197 0.03359785 -0.023974653
## studyID4 0.031578033 0.01309589 0.007840420 0.03530259 -0.013059033
## [,61] [,62] [,63] [,64] [,65]
## (Intercept) 0.75626581 0.722256668 0.79659272 0.685174699 0.86626059
## studyID1 -0.05678635 -0.024938712 -0.09783138 -0.045447647 -0.06679431
## studyID2 -0.01561288 0.009244992 -0.07768845 0.008441395 -0.06580121
## studyID3 0.03527453 -0.006813713 0.09050681 0.023880020 0.06123799
## studyID4 0.03703963 0.042379681 0.06036836 0.046491536 0.05473607
## [,66] [,67] [,68] [,69] [,70]
## (Intercept) 0.777973326 0.78532602 0.88617622 0.83138145 0.73208252
## studyID1 -0.040295795 -0.08423483 -0.04513834 -0.07048073 -0.04715621
## studyID2 -0.003152472 -0.04133572 -0.05296109 -0.06436904 -0.01543188
## studyID3 0.032365434 0.05571800 0.04345632 0.06168232 0.04105149
## studyID4 0.010984746 0.05486906 0.03720312 0.05352999 0.04101541
## [,71] [,72] [,73] [,74] [,75]
## (Intercept) 0.79628569 0.74564364 0.82963740 0.85648354 0.69383593
## studyID1 -0.07094938 -0.07820177 -0.06091010 -0.03302957 -0.08101647
## studyID2 -0.05341591 -0.01400483 -0.03722800 -0.07863538 -0.03510021
## studyID3 0.07510932 0.04600772 0.04419435 0.03720027 0.07220052
## studyID4 0.04982367 0.04899550 0.04269845 0.04971100 0.05154065
## [,76] [,77] [,78] [,79] [,80]
## (Intercept) 0.75828594 0.75491616 0.698578632 0.71157823 0.77634439
## studyID1 -0.03301151 -0.08926200 -0.038956950 -0.06451718 -0.07306696
## studyID2 0.01419652 -0.07095628 -0.004039631 -0.05402490 -0.09068076
## studyID3 0.01375530 0.08008457 0.021096937 0.04064663 0.06680122
## studyID4 0.03589495 0.05303716 0.054663702 0.06717357 0.07333525
## [,81] [,82] [,83] [,84] [,85]
## (Intercept) 0.777293438 0.707326451 0.77954551 0.7802628525 0.66377100
## studyID1 -0.022893174 0.007955915 -0.08892851 -0.0425010403 -0.03926263
## studyID2 0.009733795 0.032999077 -0.08597623 -0.0002989762 0.01150328
## studyID3 0.005883467 -0.043341692 0.08030758 0.0214859831 0.02283625
## studyID4 0.025757777 0.041900817 0.07176992 0.0288836445 0.03899032
## [,86] [,87] [,88] [,89] [,90]
## (Intercept) 0.73669370 0.68960159 0.794915405 0.950799505 0.681536133
## studyID1 -0.03100328 -0.05170864 0.011331421 -0.016988756 -0.006895492
## studyID2 0.03664492 -0.03463017 0.061178294 0.009956535 0.026448393
## studyID3 -0.01282797 0.04358591 -0.042648962 0.019935263 -0.019573161
## studyID4 0.03402930 0.06514813 -0.001067148 -0.025480966 0.035698698
## [,91] [,92] [,93] [,94] [,95]
## (Intercept) 0.77602797 0.75948032 0.74452823 0.82434660 0.766827710
## studyID1 -0.05309490 -0.05176798 -0.03932661 0.01497277 -0.001158024
## studyID2 -0.03280113 -0.07596665 0.03024806 0.05021643 0.053123917
## studyID3 0.05570932 0.04411548 0.01288461 -0.03264135 -0.022119364
## studyID4 0.03438912 0.07280730 0.03467307 -0.01740109 0.013140741
## [,96] [,97] [,98] [,99] [,100]
## (Intercept) 0.712164253 0.68855076 0.91005652 0.73466358 0.801902555
## studyID1 -0.027419866 -0.05033480 0.01390922 -0.02785560 0.033705550
## studyID2 0.034792148 -0.01435342 0.03792887 0.03455838 0.075986951
## studyID3 -0.001555805 0.03420867 -0.02364997 0.00511634 -0.055487366
## studyID4 0.023490094 0.05519212 -0.02176136 0.02956285 -0.009838992
## [,101] [,102] [,103] [,104] [,105]
## (Intercept) 0.781736304 0.78470581 0.752959053 0.71527754 0.685495223
## studyID1 -0.008643686 -0.06499234 0.004529713 -0.02264534 -0.015899240
## studyID2 -0.001231803 -0.04997590 0.060904611 0.04840013 0.035258528
## studyID3 -0.001193747 0.05255167 -0.057032177 -0.02385522 -0.008106758
## studyID4 0.018165833 0.04364129 0.033806568 0.03802453 0.034055285
## [,106] [,107] [,108] [,109] [,110]
## (Intercept) 0.79704542 0.7476354715 0.72111791 0.74695645 0.72165720
## studyID1 -0.05887184 -0.0356475247 -0.06389942 -0.05570215 -0.07781441
## studyID2 -0.04918143 0.0432040379 -0.09603090 -0.07286121 -0.07607202
## studyID3 0.04163504 0.0008598003 0.07388893 0.04790138 0.07363142
## studyID4 0.05266070 0.0313708648 0.07630438 0.07245070 0.07816349
## [,111] [,112] [,113] [,114] [,115]
## (Intercept) 0.80376501 0.76485120 0.81705387 0.82875081 0.80888621
## studyID1 -0.03805225 -0.02853643 -0.06342763 -0.02479917 -0.05067841
## studyID2 -0.09440377 -0.08578968 -0.10403666 -0.04264292 -0.07674822
## studyID3 0.04389452 0.03766355 0.07319994 0.04825242 0.05224949
## studyID4 0.06507869 0.05867997 0.05744107 0.02535254 0.05029131
## [,116] [,117] [,118] [,119] [,120]
## (Intercept) 0.76971559 0.80031381 0.67773592 0.73246771 0.920199444
## studyID1 -0.05726148 -0.01170429 -0.03978420 -0.05820645 -0.028635255
## studyID2 -0.09743218 -0.01860063 -0.02546947 -0.04608215 -0.014936005
## studyID3 0.06492941 0.00194482 0.03810171 0.04225766 0.030722022
## studyID4 0.07369688 0.04404772 0.05253060 0.05933272 -0.005775329
## [,121] [,122] [,123] [,124] [,125]
## (Intercept) 0.68638903 0.74277049 0.780366701 0.84852196 0.83508932
## studyID1 -0.04756543 -0.04507123 0.032484028 -0.01992758 -0.03278101
## studyID2 -0.06305348 -0.08707295 0.052365326 -0.04831042 -0.06898793
## studyID3 0.03784268 0.05214563 -0.049904528 0.04916471 0.05139544
## studyID4 0.07826084 0.06800002 -0.004362564 0.02194964 0.04074096
## [,126] [,127] [,128] [,129] [,130]
## (Intercept) 0.78281381 0.75122135 0.792906692 0.83061435 0.798174004
## studyID1 -0.08509840 -0.02563372 -0.006544456 -0.04042636 -0.016895820
## studyID2 -0.08089636 -0.06752592 -0.041371329 -0.09332218 0.008896812
## studyID3 0.07030577 0.04444490 0.020335893 0.05096549 0.022737650
## studyID4 0.07182748 0.03768099 0.029886048 0.05842652 0.001178961
## [,131] [,132] [,133] [,134] [,135]
## (Intercept) 0.83279134 0.77055119 0.79529298 0.770212949 0.72206627
## studyID1 -0.03249894 -0.05588641 -0.05984101 -0.007717136 -0.05108420
## studyID2 -0.05773611 -0.08000431 -0.12272278 -0.010835321 -0.03357562
## studyID3 0.05325093 0.05443385 0.07289155 -0.000998961 0.03014400
## studyID4 0.03028466 0.07123756 0.07880640 0.029770078 0.06290951
## [,136] [,137] [,138] [,139] [,140]
## (Intercept) 0.75355176 0.83987608 0.847922993 0.79849576 0.92122930
## studyID1 -0.06817237 -0.02073558 -0.002821352 -0.05508997 -0.02119358
## studyID2 -0.06984181 -0.08529225 -0.037713415 -0.11206922 -0.04029185
## studyID3 0.06816916 0.04050336 0.018295576 0.06339148 0.03103680
## studyID4 0.06584446 0.04657688 0.023198334 0.07648358 0.01416995
## [,141] [,142] [,143] [,144] [,145]
## (Intercept) 0.84593727 0.75386138 0.83072791 0.7803245723 0.686251922
## studyID1 -0.05232514 -0.05912919 -0.03626404 -0.0003778756 -0.033634340
## studyID2 -0.06891652 -0.09959083 -0.05574077 -0.0544661698 -0.006883302
## studyID3 0.06898300 0.07138559 0.04885793 0.0169098751 0.019621776
## studyID4 0.02641112 0.07453646 0.03060486 0.0398302336 0.047577855
## [,146] [,147] [,148] [,149] [,150]
## (Intercept) 0.994295658 0.75868056 0.736998188 0.80239349 0.83173664
## studyID1 0.003451089 -0.02898948 -0.008159385 -0.03713639 -0.02606258
## studyID2 -0.015622424 -0.02856729 -0.019327971 -0.08909527 -0.06267844
## studyID3 0.003596713 0.03142790 0.002786653 0.05194675 0.04593685
## studyID4 0.003970668 0.04048312 0.041452881 0.04941341 0.04592758
## [,151] [,152] [,153] [,154] [,155]
## (Intercept) 0.782046892 0.81196458 0.79575816 0.73825550 0.843025117
## studyID1 -0.043069017 -0.05438111 -0.02951726 -0.04254188 -0.009436994
## studyID2 -0.008739537 -0.09779982 -0.05008811 -0.06056540 -0.022774398
## studyID3 0.044882269 0.05155191 0.04039248 0.04223618 0.018865208
## studyID4 0.002232043 0.07168154 0.03369622 0.05826491 0.021294190
## [,156] [,157] [,158] [,159] [,160]
## (Intercept) 0.79523046 0.73211776 0.77865978 0.82731504 0.76432948
## studyID1 -0.06857357 -0.01804602 -0.02529721 -0.02367187 -0.07360264
## studyID2 -0.08933196 -0.02811177 -0.02488022 -0.06623715 -0.09670566
## studyID3 0.07264554 0.02356965 0.02124910 0.03947351 0.07008423
## studyID4 0.06070180 0.03608354 0.02148352 0.04059750 0.07288417
## [,161] [,162] [,163] [,164] [,165]
## (Intercept) 0.79564785 0.73324266 0.758657047 0.69862421 0.714064515
## studyID1 -0.06535233 -0.06967413 0.025088565 0.01481867 0.041141330
## studyID2 -0.06614586 -0.08815011 0.077507570 0.06935767 0.089172417
## studyID3 0.05231728 0.08371340 -0.045735613 -0.06501500 -0.084825904
## studyID4 0.06738471 0.07203452 -0.000632023 0.02831324 0.007365147
## [,166] [,167] [,168] [,169] [,170]
## (Intercept) 0.76206464 0.69860888 0.77912882 0.698783645 0.82970887
## studyID1 0.02741100 0.03114449 -0.00501328 0.026544742 0.04109193
## studyID2 0.04006648 0.08525124 0.02165157 0.073625804 0.08265927
## studyID3 -0.04632842 -0.07886944 -0.01017500 -0.067234723 -0.08154781
## studyID4 0.01071271 0.01472883 0.02621444 0.008789267 -0.01040782
## [,171] [,172] [,173] [,174] [,175]
## (Intercept) 0.764641487 0.7356837772 0.744862251 0.775706509 0.810909528
## studyID1 0.042384227 0.0356374376 0.009463761 0.015534162 0.011373870
## studyID2 0.082714735 0.0886933975 0.052189091 0.078354462 0.037722101
## studyID3 -0.083227855 -0.0764565172 -0.058018657 -0.054587554 -0.037483874
## studyID4 0.002158582 -0.0009766411 0.033569569 0.002091334 0.009965189
## [,176] [,177] [,178] [,179] [,180]
## (Intercept) 0.7775252965 0.70429697 0.73841259 0.819011698 0.79706231
## studyID1 0.0292088525 0.02380675 0.03737010 0.050111631 0.02285301
## studyID2 0.0724397253 0.06884931 0.04325429 0.071469049 0.06301956
## studyID3 -0.0633031869 -0.07361300 -0.05224203 -0.080042502 -0.06611550
## studyID4 -0.0002772396 0.02541665 0.00889166 -0.005854619 0.01108291
## [,181] [,182] [,183] [,184] [,185]
## (Intercept) 0.76555024 0.78894548 0.74058702 0.78033520 0.75240567
## studyID1 0.02782296 0.02334291 0.02485266 0.03419271 -0.01040240
## studyID2 0.04326448 0.07341098 0.07560952 0.07847625 0.03456229
## studyID3 -0.06362446 -0.04953065 -0.08095002 -0.05784425 -0.01802667
## studyID4 0.02773763 -0.01370129 0.02881716 -0.02204520 0.02404203
## [,186] [,187] [,188] [,189] [,190]
## (Intercept) 0.76184893 0.74562464 0.79481905 0.73666716 0.77699131
## studyID1 0.02316424 0.01300995 0.01311017 0.01990124 0.02250412
## studyID2 0.06645627 0.07078697 0.02896525 0.08232580 0.03360150
## studyID3 -0.07134436 -0.07239505 -0.04351122 -0.06967543 -0.06524106
## studyID4 0.01954875 0.03792472 0.02490085 0.01937233 0.03486877
## [,191] [,192] [,193] [,194] [,195]
## (Intercept) 0.775217415 0.775475775 0.82235502 0.758840329 0.70901594
## studyID1 0.038483677 0.020299882 0.02982408 0.036905538 0.02519451
## studyID2 0.077799503 0.050522053 0.04794190 0.097783611 0.04131071
## studyID3 -0.074604454 -0.041432545 -0.05485628 -0.087619834 -0.04996353
## studyID4 -0.002690892 -0.008773986 -0.00423774 -0.002482536 0.01642108
## [,196] [,197] [,198] [,199] [,200]
## (Intercept) 0.81903201 0.88524873 0.77016445 0.733025530 0.876775647
## studyID1 0.01679739 0.03130816 0.03748650 0.025141157 0.012671588
## studyID2 0.04569094 0.05653915 0.08188104 0.081038250 0.038936590
## studyID3 -0.04498943 -0.04887649 -0.07065736 -0.063241828 -0.031265910
## studyID4 0.01115081 -0.02015299 -0.01336101 0.003778427 0.003450027
## [,201] [,202] [,203] [,204] [,205]
## (Intercept) 0.773517426 0.76378802 0.951177126 0.76356473 0.78018506
## studyID1 0.007470932 0.02549457 -0.009162603 0.02662610 0.02868409
## studyID2 0.044019814 0.06914398 0.007089474 0.05552701 0.08186201
## studyID3 -0.036129778 -0.07139962 0.014998298 -0.07152779 -0.06400866
## studyID4 0.012241984 0.01577540 -0.025801599 0.02559676 -0.01136175
## [,206] [,207] [,208] [,209] [,210]
## (Intercept) 0.720112590 0.728136875 0.763896346 0.76201136 0.794435249
## studyID1 0.020681357 0.028010272 0.035473809 0.02173940 0.027908466
## studyID2 0.071999798 0.090634825 0.051681852 0.05765803 0.055201003
## studyID3 -0.058913382 -0.072371889 -0.055738167 -0.05997691 -0.054965426
## studyID4 0.008411493 0.000546931 -0.001679232 0.01984153 -0.008140277
## [,211] [,212] [,213] [,214] [,215]
## (Intercept) 0.81979395 0.77153796 0.865552537 0.743255122 0.733381736
## studyID1 0.03665432 0.04867535 0.008489117 0.040284248 0.030216863
## studyID2 0.04169193 0.09263218 0.006723492 0.082544495 0.089361305
## studyID3 -0.06357510 -0.08946286 -0.016496481 -0.077757416 -0.072474031
## studyID4 0.01163249 -0.00754092 0.004549845 -0.002194441 0.001945239
## [,216] [,217] [,218] [,219] [,220]
## (Intercept) 0.89719012 0.78089858 0.752672646 0.795408658 0.73734464
## studyID1 0.02948947 0.03385431 0.021925201 0.029604556 0.04290687
## studyID2 0.04953959 0.06988377 0.066726813 0.065357214 0.06669654
## studyID3 -0.04684169 -0.05833295 -0.050587143 -0.069257572 -0.07352216
## studyID4 -0.01720812 -0.01448554 0.000130078 0.007863647 0.01095949
## [,221] [,222] [,223] [,224] [,225]
## (Intercept) 0.919312099 0.8009581313 7.293674e-01 0.760452645 0.77283996
## studyID1 -0.004279109 0.0292589246 -3.939838e-02 0.030166421 0.04011954
## studyID2 0.004189207 0.0592186935 2.978391e-02 0.079133838 0.09499224
## studyID3 -0.003927197 -0.0655441570 9.741688e-05 -0.066293505 -0.07656536
## studyID4 0.002805455 -0.0006004025 2.969480e-02 -0.002267913 -0.01625933
## [,226] [,227] [,228] [,229] [,230]
## (Intercept) 0.837279815 0.76991515 0.740371580 0.818812436 0.72328916
## studyID1 0.046936537 0.01341897 0.025146752 0.028142488 -0.01659046
## studyID2 0.068395358 0.04532426 0.061559751 0.040986706 0.02871084
## studyID3 -0.078366067 -0.06224187 -0.047851959 -0.045138412 -0.01378762
## studyID4 -0.007069053 0.03482884 -0.001024127 -0.005709594 0.03752692
## [,231] [,232] [,233] [,234] [,235]
## (Intercept) 0.73155192 0.70949444 0.751551249 0.70939691 0.82038588
## studyID1 0.02268160 0.01036654 0.005348565 0.01811432 0.03047050
## studyID2 0.04645105 0.04777978 0.060524096 0.06999908 0.06160105
## studyID3 -0.06511525 -0.03777662 -0.048891561 -0.06363103 -0.07356698
## studyID4 0.02782818 0.01975608 0.026772364 0.01742128 0.01304736
## [,236] [,237] [,238] [,239] [,240]
## (Intercept) 0.763817622 0.78198513 0.77496846 0.80869258 0.71693752
## studyID1 0.009985327 0.00899530 0.03341714 0.03747458 0.02287115
## studyID2 0.039599920 0.02109572 0.06374854 0.07978300 0.05275479
## studyID3 -0.040113395 -0.02626988 -0.07214931 -0.06301681 -0.05257355
## studyID4 0.018923173 0.01282964 0.01494010 -0.01862391 0.01403267
## [,241] [,242] [,243] [,244] [,245]
## (Intercept) 0.830249142 0.80116258 0.752862537 0.70848136 0.929628042
## studyID1 -0.011841971 0.02201877 0.035653036 0.03041748 0.020699917
## studyID2 0.032503668 0.06345380 0.092280653 0.08154758 0.024617634
## studyID3 -0.005084079 -0.06542867 -0.084337759 -0.07872781 -0.029907594
## studyID4 0.004441175 0.02151126 0.008281907 0.01890732 -0.008424437
## [,246] [,247] [,248] [,249] [,250]
## (Intercept) 0.77095333 0.823750139 0.76646205 0.690308309 0.74595045
## studyID1 0.03064689 0.024172255 0.02638330 0.002955562 0.01863070
## studyID2 0.06320349 0.054321062 0.05383868 0.046553511 0.07422568
## studyID3 -0.07377868 -0.049669748 -0.06315695 -0.040819611 -0.05783279
## studyID4 0.01438112 -0.009076041 0.01328449 0.025042445 0.01820590
## [,251] [,252] [,253] [,254] [,255]
## (Intercept) 0.68211183 0.714891524 0.75577272 0.804446870 0.813340799
## studyID1 -0.02318971 0.009508865 0.02640145 0.034653687 0.012705617
## studyID2 0.06022882 0.068352138 0.04948395 0.069363901 0.052102025
## studyID3 -0.02166162 -0.057403790 -0.05508302 -0.072284814 -0.042003353
## studyID4 0.03161894 0.025058696 0.01107951 0.001291682 0.007612096
## [,256] [,257] [,258] [,259] [,260]
## (Intercept) 0.71431541 0.74343698 0.75913332 0.719306761 0.71682425
## studyID1 0.02829487 0.03159644 0.02816117 0.002432742 0.01855319
## studyID2 0.07311488 0.05627212 0.06921216 0.067960680 0.07827029
## studyID3 -0.06980319 -0.06556969 -0.07131701 -0.048902883 -0.06401136
## studyID4 0.01468102 0.02861709 0.01652813 0.018417019 0.01704000
## [,261] [,262] [,263] [,264] [,265]
## (Intercept) 0.84422405 0.6898202085 0.76157711 0.752370882 0.878952965
## studyID1 0.04569043 0.0002687865 0.02284337 0.010344882 0.003680280
## studyID2 0.08079096 0.0680696337 0.05088330 0.070107144 0.008995664
## studyID3 -0.07762354 -0.0431904470 -0.05163283 -0.056760973 -0.016680545
## studyID4 -0.02121520 0.0230005194 0.01441105 0.004976764 0.012146705
## [,266] [,267] [,268] [,269] [,270]
## (Intercept) 0.857285575 0.769614563 0.78851638 0.83388525 0.768343122
## studyID1 0.009194762 -0.006674724 0.03207236 -0.05609380 -0.015169156
## studyID2 0.007187361 0.012171909 0.04942985 -0.02356836 0.033808478
## studyID3 -0.025768620 0.005043750 -0.02880675 0.04708957 0.014449195
## studyID4 0.022094319 0.004764073 -0.02533376 0.02380204 -0.003291337
## [,271] [,272] [,273] [,274] [,275]
## (Intercept) 0.775097575 0.88864635 0.82427868 0.89875222 0.84139954
## studyID1 0.004143031 0.02145986 -0.02849903 0.03095694 0.03411916
## studyID2 0.049359465 0.03536371 -0.01609251 0.02193190 0.06888598
## studyID3 -0.018152645 -0.02532572 0.05915309 -0.01932814 -0.04810339
## studyID4 -0.014342458 -0.01589591 -0.01022578 -0.02436261 -0.03604400
## [,276] [,277] [,278] [,279] [,280]
## (Intercept) 0.81489939 0.83599043 0.82811115 0.800744411 0.78554751
## studyID1 0.02474405 0.01464060 0.03020380 0.003740254 0.02190307
## studyID2 0.04868097 0.05309238 0.07477849 0.063136280 0.03450770
## studyID3 -0.02581139 -0.01995640 -0.04240173 -0.020612076 -0.01226889
## studyID4 -0.03027584 -0.03579445 -0.03439616 -0.030614352 -0.03443260
## [,281] [,282] [,283] [,284] [,285]
## (Intercept) 0.87078112 0.80161103 0.819581286 0.90013419 0.81937970
## studyID1 0.03184734 -0.05699026 0.020635506 0.01236438 0.02559403
## studyID2 0.03463080 -0.02915175 0.029018972 0.03803109 0.05132595
## studyID3 -0.03070855 0.07110286 -0.024770864 -0.01055298 -0.02983041
## studyID4 -0.02502824 0.01476219 -0.006930657 -0.03325448 -0.03089382
## [,286] [,287] [,288] [,289] [,290]
## (Intercept) 0.88305230 0.833142203 0.829507137 0.85971400 0.892126683
## studyID1 -0.01018812 -0.000736515 0.006065787 0.03547778 -0.015216408
## studyID2 -0.02929212 0.035324935 0.026086503 0.05628617 0.008503198
## studyID3 0.02264146 0.012843149 -0.011251936 -0.03618365 0.022223667
## studyID4 0.01497964 -0.040627483 -0.016913956 -0.03648419 -0.021859625
## [,291] [,292] [,293] [,294] [,295]
## (Intercept) 0.77457812 0.83346289 0.774097674 0.790703726 0.80766938
## studyID1 0.02467280 0.03589345 -0.022816674 -0.024105622 -0.01666685
## studyID2 0.07570170 0.04770027 0.035220274 0.027070278 -0.05650662
## studyID3 -0.02891056 -0.04391389 0.013225757 0.015225074 0.03960652
## studyID4 -0.03618303 -0.02240439 -0.004531518 -0.005067104 0.02051915
## [,296] [,297] [,298] [,299] [,300]
## (Intercept) 0.86998797 0.751584083 0.793758231 0.783084750 0.731603029
## studyID1 0.04591000 -0.002705337 -0.024992885 -0.020913008 0.040611838
## studyID2 0.07468108 0.009191078 0.017003316 0.017862296 0.055511251
## studyID3 -0.05273826 0.009894345 0.018783055 0.017905819 -0.062774205
## studyID4 -0.05028962 -0.006737985 -0.004730267 -0.004767464 0.001779538
## [,301] [,302] [,303] [,304] [,305]
## (Intercept) 0.87016107 0.79058890 0.74879774 0.797481106 0.728822394
## studyID1 0.01730287 0.03691538 -0.02328578 0.022884189 0.008971865
## studyID2 0.03613738 0.06390194 0.02786126 0.035804964 0.061830036
## studyID3 -0.02140341 -0.04597544 0.01155486 -0.029526230 -0.025523167
## studyID4 -0.02473712 -0.03381870 0.01316431 0.001568224 -0.011301874
## [,306] [,307] [,308] [,309] [,310]
## (Intercept) 0.787528886 0.84031012 0.7706429751 0.79872583 0.71252781
## studyID1 -0.003607337 0.02401393 0.0009341721 0.03692195 -0.04813534
## studyID2 -0.011832843 0.06382851 0.0290290758 0.05459794 0.02807707
## studyID3 0.005065909 -0.03285835 0.0171577252 -0.04110413 0.03427317
## studyID4 0.011558535 -0.03408249 -0.0269871893 -0.02307477 0.01317112
## [,311] [,312] [,313] [,314] [,315]
## (Intercept) 0.779882526 0.7339964125 0.77745712 0.694296807 0.84766215
## studyID1 -0.025823266 0.0037988248 0.04080740 -0.012374933 0.01442969
## studyID2 0.007134511 0.0666071249 0.08290731 0.029006841 0.02367997
## studyID3 0.019111803 -0.0281344862 -0.05504365 0.001708666 -0.01677443
## studyID4 0.004397211 0.0007925347 -0.04218851 0.020623248 -0.02242491
## [,316] [,317] [,318] [,319] [,320]
## (Intercept) 0.945105260 0.718574497 0.81812601 0.902169610 0.794449303
## studyID1 -0.012583092 0.029363033 0.02351454 0.005904420 -0.016198969
## studyID2 0.008253078 0.065744599 0.05745321 0.013894874 0.033127377
## studyID3 0.021616989 -0.054113230 -0.03644015 0.005067076 0.004555850
## studyID4 -0.032086153 -0.002738664 -0.02822154 -0.031919290 -0.006932786
## [,321] [,322] [,323] [,324] [,325]
## (Intercept) 0.74783111 0.75247801 0.85395209 0.77455139 0.8958695359
## studyID1 -0.05706913 0.04179512 0.04276247 -0.01428122 -0.0035184493
## studyID2 0.01785964 0.08452324 0.06348240 0.04577113 0.0284474475
## studyID3 0.04274130 -0.06319505 -0.04843983 0.01665750 0.0004368222
## studyID4 0.01599446 -0.02837031 -0.04068804 -0.02600643 -0.0208833856
## [,326] [,327] [,328] [,329] [,330]
## (Intercept) 0.80434904 0.717536037 0.722218762 0.8189426312 0.722206578
## studyID1 0.01603516 0.005165708 0.014334102 0.0006278693 0.004701180
## studyID2 0.05039727 0.061868812 0.040524773 0.0372456852 0.052228871
## studyID3 -0.02269172 -0.009229701 -0.023251479 -0.0082735387 -0.020857193
## studyID4 -0.02047167 -0.012178876 -0.003506182 -0.0238203977 -0.006831181
## [,331] [,332] [,333] [,334] [,335]
## (Intercept) 0.81167785 0.786044405 0.796416828 0.7795027127 0.767715719
## studyID1 0.03149773 0.002308984 0.017955804 0.0002811639 -0.037951163
## studyID2 0.08221579 0.047295947 0.045537541 0.0489634309 0.011457508
## studyID3 -0.04984094 -0.016987897 -0.006474689 0.0108910357 0.043772614
## studyID4 -0.03194586 -0.005847084 -0.027033747 -0.0358620555 0.006349858
## [,336] [,337] [,338] [,339] [,340]
## (Intercept) 0.762183965 0.724952341 0.7451600506 0.6823345627 0.844520817
## studyID1 -0.040146220 0.024826961 -0.0078580478 -0.0158146493 0.001125325
## studyID2 0.027598441 0.069473080 0.0644824071 0.0113435811 0.042667603
## studyID3 0.030354234 -0.056157438 0.0007031798 0.0002872127 0.009926702
## studyID4 0.001197908 0.002072715 -0.0287077914 0.0288302158 -0.033992940
## [,341] [,342] [,343] [,344] [,345]
## (Intercept) 0.697107368 0.86865701 0.776067851 0.77718442 0.812484595
## studyID1 0.016231274 0.02877342 0.001547535 0.01633404 0.015818858
## studyID2 0.068937950 0.05385554 0.029319677 0.06999256 0.052880051
## studyID3 -0.036315572 -0.02249164 -0.005377371 -0.03581575 -0.008391383
## studyID4 0.004030687 -0.04148630 -0.007594990 -0.01736160 -0.047274683
## [,346] [,347] [,348] [,349] [,350]
## (Intercept) 0.7640295916 0.76795357 0.742150585 0.75644260 0.736912909
## studyID1 0.0002608535 0.04505554 0.006489672 0.01049444 0.027963380
## studyID2 0.0279280350 0.09670415 0.079823263 0.06777800 0.071836656
## studyID3 -0.0042255274 -0.06663694 -0.028394722 -0.02665025 -0.065071607
## studyID4 -0.0139760024 -0.03057568 -0.007665865 -0.01680212 0.006786251
## [,351] [,352] [,353] [,354] [,355]
## (Intercept) 0.765786442 0.80284316 0.871344367 0.732445406 0.74628071
## studyID1 0.017989790 0.02779058 -0.004602241 0.032957466 0.02265542
## studyID2 0.066309005 0.05105308 0.033620944 0.089602432 0.06713721
## studyID3 -0.035067633 -0.02579492 0.001622183 -0.060922425 -0.03465547
## studyID4 -0.005761592 -0.01969573 -0.032071156 -0.009892056 -0.01765999
## [,356] [,357] [,358] [,359] [,360]
## (Intercept) 0.779374577 0.733990731 0.752619521 0.803690593 0.71978303
## studyID1 0.046062210 0.019858529 0.053102310 0.011845249 0.01105676
## studyID2 0.067342009 0.064489047 0.076740133 0.045366535 0.02920423
## studyID3 -0.062485183 -0.046683079 -0.082881891 -0.006174756 -0.02174212
## studyID4 -0.006263496 0.002736641 -0.001590062 -0.031145890 0.01304749
## [,361] [,362] [,363] [,364] [,365]
## (Intercept) 0.946684988 0.79641311 0.7462432128 0.896724603 0.853845284
## studyID1 0.002061181 0.02704099 -0.0005650543 0.006848036 -0.010342500
## studyID2 0.010697255 0.03355325 0.0376795454 0.018645202 -0.006765324
## studyID3 0.008929256 -0.02027110 -0.0029862066 -0.006093542 0.018079234
## studyID4 -0.035624641 -0.02114129 -0.0008952213 -0.015860948 -0.012222357
## [,366] [,367] [,368] [,369] [,370]
## (Intercept) 0.77784791 0.80600209 0.73326246 0.81234166 0.810731431
## studyID1 -0.02226897 0.03894387 0.01141714 -0.03764754 0.016766465
## studyID2 0.01857757 0.08403722 0.06837759 -0.03484508 0.033155329
## studyID3 0.03328142 -0.06401881 -0.01734980 0.03774354 -0.018754923
## studyID4 -0.01727324 -0.02109436 -0.02232769 0.02538523 -0.003893008
## [,371] [,372] [,373] [,374] [,375]
## (Intercept) 0.81585951 0.7183436274 0.808581307 0.84935241 0.819413717
## studyID1 0.03240437 0.0273035124 0.001806393 0.03935983 -0.019104588
## studyID2 0.05984491 0.0666742105 0.032388669 0.06997074 -0.026080573
## studyID3 -0.03315300 -0.0520760552 -0.002206643 -0.04615545 0.042478897
## studyID4 -0.03959567 0.0003502657 -0.009950705 -0.03639585 0.009474868
## [,376] [,377] [,378] [,379] [,380]
## (Intercept) 0.7372641808 0.80873902 0.780909166 0.80344637 0.786785669
## studyID1 -0.0001873546 0.02840926 0.012095761 0.03393542 -0.017227932
## studyID2 0.0518379031 0.07443093 0.062490114 0.05646912 -0.009487205
## studyID3 -0.0250936218 -0.04623793 -0.038535002 -0.03349882 0.039150556
## studyID4 0.0023552335 -0.02706743 -0.009435946 -0.02583660 0.002509212
## [,381] [,382] [,383] [,384] [,385]
## (Intercept) 0.86456126 0.77952892 0.83895766 0.85298515 0.75242060
## studyID1 0.04286745 0.03296716 0.04430173 0.04303319 0.03577378
## studyID2 0.06351655 0.08378698 0.08032416 0.06912860 0.04496173
## studyID3 -0.05076778 -0.06484624 -0.06142179 -0.05220005 -0.03143618
## studyID4 -0.04029438 -0.02193542 -0.03055457 -0.03436416 -0.01696261
## [,386] [,387] [,388] [,389] [,390]
## (Intercept) 0.869957543 0.73345881 0.83130598 0.800292039 0.725299909
## studyID1 0.009169024 0.03618691 0.01576982 -0.040769943 0.003949265
## studyID2 0.040626596 0.07567538 0.04827505 -0.003528821 -0.002128863
## studyID3 0.009033573 -0.05017749 -0.02467715 0.043799146 -0.014455729
## studyID4 -0.043130457 -0.02357239 -0.02518621 -0.006386129 0.037671720
## [,391] [,392] [,393] [,394] [,395]
## (Intercept) 0.74988797 0.74457290 0.6893487482 0.832689905 0.702165812
## studyID1 -0.04628611 0.02122099 -0.0001088894 -0.035075780 -0.026030766
## studyID2 -0.02177168 0.07040471 0.0377090494 -0.001479279 0.019995404
## studyID3 0.05435280 -0.03500065 -0.0097536695 0.041888864 -0.004190248
## studyID4 0.02323767 -0.02306096 0.0184070054 -0.020470852 0.045735471
## [,396] [,397] [,398] [,399] [,400]
## (Intercept) 0.83945168 0.699291239 0.73873496 0.700851278 0.666148219
## studyID1 0.02953762 -0.009008707 0.03375150 -0.004950581 -0.020189608
## studyID2 0.07624022 0.028304814 0.05469864 0.032196106 0.031075043
## studyID3 -0.05092099 -0.005774625 -0.05951367 -0.002098953 -0.008624057
## studyID4 -0.01971329 0.033866949 0.02213125 0.026114609 0.047097304
## [,401] [,402] [,403] [,404] [,405]
## (Intercept) 7.897582e-01 0.6799091971 0.808830111 0.719070084 0.712003379
## studyID1 6.960577e-05 -0.0221009123 -0.008944344 -0.017312162 0.009786735
## studyID2 4.364252e-02 0.0292393421 0.036923980 0.004816913 0.071695105
## studyID3 -2.160660e-02 -0.0006298635 0.008451418 -0.003017418 -0.045063299
## studyID4 1.510567e-02 0.0271393432 0.004138461 0.049857442 0.018558514
## [,406] [,407] [,408] [,409] [,410]
## (Intercept) 0.771056824 0.744016336 0.777516506 0.692748755 0.678840276
## studyID1 0.003691062 -0.008090234 0.031896201 0.005781017 -0.025635881
## studyID2 0.044249828 0.058774459 0.052578284 0.046942151 0.015918233
## studyID3 -0.028795115 -0.020729974 -0.044964173 -0.033726646 0.007267168
## studyID4 0.016826971 0.004961282 0.004919753 0.023477624 0.050671552
## [,411] [,412] [,413] [,414] [,415]
## (Intercept) 0.728672367 0.801111862 0.813576233 0.806644881 0.740903094
## studyID1 -0.044676597 0.038917831 -0.007258932 -0.010598981 -0.003073551
## studyID2 -0.005354144 0.073670585 0.030766618 0.009120624 0.006477557
## studyID3 0.031695903 -0.068123569 0.006599163 0.017828427 -0.001293776
## studyID4 0.037792942 -0.000417097 0.009439595 0.015284037 0.022880126
## [,416] [,417] [,418] [,419] [,420]
## (Intercept) 0.76950758 0.9185513140 0.751561121 0.747173435 0.798888810
## studyID1 0.03232658 0.0032445671 -0.022081775 -0.005849462 0.005858569
## studyID2 0.08177263 0.0012902983 0.016637090 0.046509905 0.037803936
## studyID3 -0.06314948 -0.0006865415 0.001984645 -0.018523244 -0.015741226
## studyID4 -0.01251956 0.0033679152 0.026349067 0.006157306 -0.003505027
## [,421] [,422] [,423] [,424] [,425]
## (Intercept) 0.74588011 0.746285373 0.799650880 0.693350221 0.804108383
## studyID1 0.02039598 -0.053075413 -0.050593403 -0.008578326 0.004106392
## studyID2 0.07182336 0.006188479 0.001785762 0.036534607 0.049773928
## studyID3 -0.06385012 0.050310971 0.041615904 -0.017181800 -0.037256592
## studyID4 0.02191466 0.022001909 0.027813490 0.046679111 0.026289350
## [,426] [,427] [,428] [,429] [,430]
## (Intercept) 0.74425821 0.7850377645 0.77685758 0.874383280 7.427147e-01
## studyID1 -0.01788140 -0.0119133844 -0.05066339 0.028957523 2.965202e-05
## studyID2 0.02547895 0.0275229073 -0.02232381 0.029723611 5.802666e-02
## studyID3 -0.00854311 0.0009391663 0.05149927 -0.037223429 -2.177665e-02
## studyID4 0.03341306 0.0222272468 0.04870666 -0.001249419 2.058953e-02
## [,431] [,432] [,433] [,434] [,435]
## (Intercept) 0.84976749 0.8130781647 0.81216062 0.695340352 0.782637326
## studyID1 -0.03907588 0.0018977393 -0.04624368 0.004594381 -0.008692320
## studyID2 -0.02488543 0.0397615474 -0.05340917 0.054151741 0.042859193
## studyID3 0.05862850 -0.0002469969 0.04646356 -0.033917195 -0.005872164
## studyID4 0.01527157 -0.0133397578 0.04592951 0.035063499 0.016844135
## [,436] [,437] [,438] [,439] [,440]
## (Intercept) 0.830634027 0.724219460 0.803724443 0.76600424 0.837445683
## studyID1 0.003700076 -0.019729116 0.011749914 -0.05142296 -0.018938808
## studyID2 0.037174374 0.049707569 0.054836593 -0.02811180 0.014262789
## studyID3 -0.005178159 0.007270035 -0.033117921 0.05192527 0.011493413
## studyID4 -0.024382057 0.014085487 0.001731155 0.02479816 0.008621651
## [,441] [,442] [,443] [,444] [,445]
## (Intercept) 0.745950582 0.80923659 0.721182354 0.8180263766 0.72163765
## studyID1 -0.004252005 0.03917185 -0.024892574 -0.0007579445 0.01731538
## studyID2 0.052258895 0.06353784 0.010298725 0.0300111631 0.09418452
## studyID3 -0.022700005 -0.04675638 0.006192526 -0.0130079935 -0.06533619
## studyID4 0.029516559 -0.02564925 0.051186137 0.0020993686 0.01000201
## [,446] [,447] [,448] [,449] [,450]
## (Intercept) 0.688906548 0.8596210370 0.806981995 0.71336019 0.687788342
## studyID1 -0.014122469 0.0288074761 -0.018940143 0.01432311 0.014615230
## studyID2 0.017481112 0.0298559541 0.013598853 0.06538177 0.063671897
## studyID3 0.004430318 -0.0347233321 0.019462753 -0.03975677 -0.032377761
## studyID4 0.030144107 -0.0009961312 -0.005842216 0.02303492 0.008205139
## [,451] [,452] [,453] [,454] [,455]
## (Intercept) 0.810299106 0.865075277 0.70590504 0.757463907 0.701428554
## studyID1 -0.002154955 0.022420175 -0.02296554 -0.021502849 0.001793737
## studyID2 0.046637024 0.041800581 0.05865546 0.004006560 0.036078983
## studyID3 -0.015309191 -0.036887625 -0.01216706 0.001670128 -0.030049896
## studyID4 0.008501660 -0.005842737 0.02770816 0.034951070 0.040758429
## [,456] [,457] [,458] [,459] [,460]
## (Intercept) 0.708612894 0.761692434 0.676347407 0.764311134 0.729933745
## studyID1 -0.011694074 0.020907581 -0.004511749 -0.008774505 0.009124336
## studyID2 0.026309257 0.056037829 0.035835850 0.057594389 0.052696713
## studyID3 0.007375605 -0.046123713 -0.023412310 -0.030905548 -0.048129804
## studyID4 0.021158940 0.003715777 0.045841697 0.035237175 0.023650527
## [,461] [,462] [,463] [,464] [,465]
## (Intercept) 0.72764925 0.74633071 0.684111517 0.832710542 0.81067492
## studyID1 0.01444856 -0.02942660 -0.011951880 0.010197703 -0.05975306
## studyID2 0.08308315 0.01445299 0.044929584 0.018234345 -0.03946627
## studyID3 -0.05574226 0.01827845 -0.001895898 -0.012775365 0.05699626
## studyID4 0.01321512 0.03555220 0.024417938 0.001329241 0.05252579
## [,466] [,467] [,468] [,469] [,470]
## (Intercept) 0.758634026 0.715710894 0.74002245 0.9142019160 0.777863392
## studyID1 -0.003003013 0.013155696 0.01650803 0.0078506065 0.016593681
## studyID2 0.029412095 0.081928347 0.06204407 0.0095403354 0.072802645
## studyID3 -0.010443842 -0.040255512 -0.04100088 0.0005909371 -0.047498314
## studyID4 0.010677098 0.008049699 0.00704545 0.0002256434 -0.001468372
## [,471] [,472] [,473] [,474] [,475]
## (Intercept) 0.679874232 0.73634847 0.767809674 8.210647e-01 0.75121314
## studyID1 -0.029870873 0.02607450 -0.044601750 5.472864e-03 0.02738022
## studyID2 0.025909941 0.06796663 -0.003774917 1.277730e-02 0.05382670
## studyID3 0.009206168 -0.05549698 0.047920935 -4.550567e-04 -0.06861233
## studyID4 0.049141356 0.01476263 0.022744628 -6.533592e-05 0.03200722
## [,476] [,477] [,478] [,479] [,480]
## (Intercept) 0.683864616 0.875744510 0.736130803 0.729744486 0.753563344
## studyID1 -0.005605218 0.014602432 -0.005361074 -0.018669221 0.005502440
## studyID2 0.044617476 0.023465218 0.057120628 0.015083857 0.050842508
## studyID3 -0.018914048 -0.008454238 -0.012702306 0.006820543 -0.027417071
## studyID4 0.036662991 -0.009775050 0.010888696 0.036042771 0.008662072
## [,481] [,482] [,483] [,484] [,485]
## (Intercept) 0.744437030 7.425506e-01 0.73992176 0.7244169889 0.74050190
## studyID1 -0.018037874 -4.428348e-05 0.01244645 -0.0001935564 -0.02455606
## studyID2 0.050315685 5.104708e-02 0.06684344 0.0142263570 0.03162279
## studyID3 0.014884367 -2.566240e-02 -0.04833190 -0.0330110399 0.01527841
## studyID4 0.001217342 1.686975e-02 0.01795061 0.0487775489 0.01344153
## [,486] [,487] [,488] [,489] [,490]
## (Intercept) 0.73060590 0.72146498 0.76024346 0.75035138 0.749890332
## studyID1 -0.01318728 -0.04379858 0.02096242 -0.03268324 0.023204378
## studyID2 0.04924534 -0.03492104 0.07020008 -0.00793699 0.084149140
## studyID3 -0.01180934 0.04248216 -0.06366889 0.03432892 -0.061944500
## studyID4 0.02965500 0.05833628 0.03066558 0.04501529 0.001704515
## [,491] [,492] [,493] [,494] [,495]
## (Intercept) 0.752555830 0.853583542 0.75308582 8.541475e-01 0.83694979
## studyID1 0.003415827 0.027704938 -0.01331162 1.833433e-03 0.03537389
## studyID2 0.034048485 0.047558493 0.04237549 3.143937e-02 0.06815511
## studyID3 -0.024363299 -0.031885967 -0.01194291 -1.612792e-02 -0.05669406
## studyID4 0.010380754 -0.009852011 0.02949756 1.502877e-05 -0.01178907
## [,496] [,497] [,498] [,499] [,500]
## (Intercept) 0.78016942 0.733039781 0.718857227 0.742227258 0.75996062
## studyID1 0.01444723 -0.020785732 -0.052883563 -0.025002429 0.05250434
## studyID2 0.04297864 0.028703336 -0.005326699 0.037601657 0.10063151
## studyID3 -0.02439402 0.006397359 0.042369213 0.003827157 -0.07531051
## studyID4 0.01013984 0.012491046 0.039940684 0.017100753 -0.03207805
## [,501] [,502] [,503] [,504] [,505]
## (Intercept) 0.810746064 0.72048196 0.701067819 0.769044679 0.733514743
## studyID1 -0.006855010 -0.02560316 -0.016078825 -0.035896258 -0.042590469
## studyID2 0.011623086 0.04991596 0.033684624 0.005070562 0.009686297
## studyID3 0.019215360 -0.01113248 0.002774911 0.044597810 0.020055153
## studyID4 0.002483649 0.03828162 0.030069934 0.017120490 0.053394228
## [,506] [,507] [,508] [,509] [,510]
## (Intercept) 0.752173076 0.771915753 0.721945584 0.79685561 0.74492286
## studyID1 0.027390614 0.016357521 -0.016727514 0.01346359 -0.01858812
## studyID2 0.068276408 0.046238265 0.035383692 0.05686315 0.02219381
## studyID3 -0.053422087 -0.032240340 -0.002957782 -0.04647820 0.00277446
## studyID4 0.005780032 0.009595829 0.019192709 0.01397931 0.03113130
## [,511] [,512] [,513] [,514] [,515]
## (Intercept) 0.74071554 0.676658241 0.756324461 0.74800700 0.7770147356
## studyID1 0.02047680 0.008870223 0.009938951 0.03005037 0.0011948298
## studyID2 0.02568777 0.038956723 0.058327726 0.05357977 0.0580620059
## studyID3 -0.04189173 -0.017908047 -0.030205814 -0.06496324 -0.0163979198
## studyID4 0.03499053 0.023263217 0.002179003 0.02020251 0.0004167877
## [,516] [,517] [,518] [,519] [,520]
## (Intercept) 0.7311898484 0.754463485 0.7206435964 0.80566139 0.764521962
## studyID1 -0.0008093035 -0.004837788 0.0004121979 0.02752795 0.007802459
## studyID2 0.0442242280 0.058818438 0.0120918270 0.02637212 0.071750731
## studyID3 -0.0315420997 -0.023388977 -0.0159895344 -0.03517877 -0.038128789
## studyID4 0.0368351695 0.017869311 0.0403714813 0.01269520 0.004185801
## [,521] [,522] [,523] [,524] [,525]
## (Intercept) 0.75665251 0.699525659 0.856598972 0.72821245 0.730470037
## studyID1 0.01285632 -0.004518647 0.028842546 -0.01410605 -0.008636468
## studyID2 0.03069859 0.063560296 0.042470873 0.04228478 0.045706635
## studyID3 -0.03177858 -0.030878366 -0.036008162 -0.01998070 -0.028121033
## studyID4 0.01958731 0.019057777 -0.005984491 0.03216216 0.033086364
## [,526] [,527] [,528] [,529] [,530]
## (Intercept) 0.70223986 0.71244265 0.785678744 0.738176172 0.73641416
## studyID1 -0.01746276 -0.01933295 0.006692514 0.025239392 -0.00317709
## studyID2 0.05586032 0.04711987 0.040388643 0.095362831 0.01739013
## studyID3 -0.02224091 -0.01784792 -0.022131889 -0.060049701 -0.01385369
## studyID4 0.02695664 0.03526911 -0.002357003 -0.004435628 0.02894158
## [,531] [,532] [,533] [,534] [,535]
## (Intercept) 0.766110288 0.708200183 0.799015536 0.720706199 0.71481278
## studyID1 0.025297167 0.020358384 0.030659330 -0.009673549 0.02407470
## studyID2 0.053671506 0.076916056 0.069250917 0.024998278 0.07453381
## studyID3 -0.040286464 -0.049199193 -0.061427824 -0.003034226 -0.07994656
## studyID4 0.002392001 0.006873404 0.009165657 0.028791037 0.03979205
## [,536] [,537] [,538] [,539] [,540]
## (Intercept) 0.732889428 0.819792088 0.716107670 0.711549246 0.71134534
## studyID1 0.014441269 0.016273427 0.009606795 -0.024090188 0.01426914
## studyID2 0.052814121 0.009091139 0.071475948 0.056087135 0.04554835
## studyID3 -0.031631462 -0.029607341 -0.060334723 -0.009709743 -0.03473561
## studyID4 -0.001261994 0.022074805 0.026160277 0.021400033 0.01278058
## [,541] [,542] [,543] [,544] [,545]
## (Intercept) 0.783865478 0.805088814 0.71002602 0.74305595 0.71015300
## studyID1 -0.001919176 0.021251354 0.02755140 0.02763631 0.02920989
## studyID2 0.053990729 0.053802331 0.06720132 0.04506846 0.07266060
## studyID3 -0.033642488 -0.043198064 -0.06841275 -0.04864597 -0.06833452
## studyID4 0.025918273 0.005111637 0.02365552 0.01940027 0.02456472
## [,546] [,547] [,548] [,549] [,550]
## (Intercept) 0.8179097079 0.77110019 0.738174482 0.710568749 0.72194328
## studyID1 0.0008472454 0.01646614 0.005439632 0.009002755 -0.01806964
## studyID2 0.0334616464 0.05946702 0.059291991 0.027261000 0.05771934
## studyID3 -0.0202960144 -0.03340806 -0.028568432 -0.017373629 -0.02205352
## studyID4 0.0133352077 -0.01441851 0.005949941 0.028992099 0.01705428
## [,551]
## (Intercept) 0.72137640
## studyID1 0.02473271
## studyID2 0.06852849
## studyID3 -0.05749551
## studyID4 0.01167007
##
## $f.perms
## [,1]
## [1,] 1.0057677
## [2,] 0.8054855
## [3,] 1.2880091
## [4,] 0.9516901
## [5,] 0.8671892
## [6,] 0.9393818
## [7,] 1.1256861
## [8,] 0.9205191
## [9,] 0.9421464
## [10,] 1.1423109
## [11,] 0.8785887
## [12,] 1.2518957
## [13,] 0.9010014
## [14,] 1.1185882
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## [691,] 1.2439383
## [692,] 1.0311730
## [693,] 1.0456158
## [694,] 1.2215064
## [695,] 1.2006510
## [696,] 0.9380796
## [697,] 0.8938708
## [698,] 1.0355192
## [699,] 0.9737018
## [700,] 0.8507604
## [701,] 0.8670239
## [702,] 1.1692430
## [703,] 0.8403392
## [704,] 1.1199740
## [705,] 0.9963859
## [706,] 0.9990733
## [707,] 1.0162311
## [708,] 1.0341976
## [709,] 0.9810103
## [710,] 0.8777908
## [711,] 1.2526917
## [712,] 0.8477986
## [713,] 0.7685648
## [714,] 0.8762461
## [715,] 1.0979232
## [716,] 1.2918279
## [717,] 1.1939909
## [718,] 1.2278126
## [719,] 1.0298535
## [720,] 0.9428603
## [721,] 0.9490798
## [722,] 0.9673585
## [723,] 1.0114237
## [724,] 1.0510092
## [725,] 1.1203819
## [726,] 1.1013198
## [727,] 0.7264765
## [728,] 1.1151590
## [729,] 0.9234223
## [730,] 1.1248783
## [731,] 1.1329955
## [732,] 1.1432316
## [733,] 1.0238204
## [734,] 0.8537466
## [735,] 0.9519485
## [736,] 0.9073299
## [737,] 0.9594492
## [738,] 1.0723696
## [739,] 1.0876319
## [740,] 0.8845229
## [741,] 0.7839135
## [742,] 1.0729312
## [743,] 0.9377682
## [744,] 0.9483265
## [745,] 1.0267890
## [746,] 1.0842175
## [747,] 0.9538781
## [748,] 1.1176718
## [749,] 1.0473086
## [750,] 1.0296816
## [751,] 1.0047296
## [752,] 0.6912411
## [753,] 1.0378421
## [754,] 1.0636281
## [755,] 1.0054485
## [756,] 1.0048895
## [757,] 1.2691119
## [758,] 0.7651077
## [759,] 1.0168828
## [760,] 0.8315314
## [761,] 0.8763902
## [762,] 1.0142976
## [763,] 0.9747320
## [764,] 1.0109722
## [765,] 0.9506989
## [766,] 0.9107783
## [767,] 0.9009776
## [768,] 0.8178042
## [769,] 0.7847201
## [770,] 1.0127302
## [771,] 0.9319079
## [772,] 0.9684338
## [773,] 0.9400620
## [774,] 1.0708400
## [775,] 0.9143175
## [776,] 1.2121706
## [777,] 1.0774627
## [778,] 1.1476437
## [779,] 0.8856506
## [780,] 0.8831399
## [781,] 1.0582377
## [782,] 0.9140829
## [783,] 1.0796840
## [784,] 1.0771434
## [785,] 0.9550974
## [786,] 1.0549494
## [787,] 1.1052545
## [788,] 0.8654340
## [789,] 0.8157686
## [790,] 0.9068657
## [791,] 0.8915752
## [792,] 1.0388842
## [793,] 1.0287595
## [794,] 0.8524699
## [795,] 0.8077577
## [796,] 0.9580752
## [797,] 0.9374105
## [798,] 0.9826538
## [799,] 0.9689110
## [800,] 1.1710747
## [801,] 0.9558902
## [802,] 0.9125877
## [803,] 0.9551740
## [804,] 1.0292554
## [805,] 1.1451676
## [806,] 0.9525920
## [807,] 1.1408419
## [808,] 1.1074725
## [809,] 1.1272611
## [810,] 1.0647460
## [811,] 1.0589698
## [812,] 0.9584321
## [813,] 1.1016896
## [814,] 1.1578242
## [815,] 1.0100325
## [816,] 1.0054449
## [817,] 1.2857114
## [818,] 1.0971717
## [819,] 0.9185060
## [820,] 1.0388125
## [821,] 0.8576119
## [822,] 0.9148024
## [823,] 1.1123266
## [824,] 1.1014018
## [825,] 0.8449488
## [826,] 1.0410927
## [827,] 1.1763150
## [828,] 0.8945159
## [829,] 0.8624109
## [830,] 1.3648020
## [831,] 1.0425725
## [832,] 0.7978792
## [833,] 1.2495995
## [834,] 1.0417452
## [835,] 0.8504412
## [836,] 1.2292936
## [837,] 1.1086572
## [838,] 1.1779306
## [839,] 0.9075120
## [840,] 0.8576346
## [841,] 1.0436219
## [842,] 1.0560922
## [843,] 1.0115656
## [844,] 1.0373259
## [845,] 1.1087209
## [846,] 0.9809984
## [847,] 0.9331121
## [848,] 1.2779622
## [849,] 0.9239388
## [850,] 1.3836863
## [851,] 0.8803244
## [852,] 1.1214588
## [853,] 0.9110840
## [854,] 0.7311550
## [855,] 0.9348233
## [856,] 1.0440588
## [857,] 1.0925039
## [858,] 1.0735991
## [859,] 1.0732437
## [860,] 1.1096876
## [861,] 1.0160602
## [862,] 0.9854514
## [863,] 1.2200049
## [864,] 0.9999910
## [865,] 0.9378808
## [866,] 0.9574947
## [867,] 0.9861551
## [868,] 1.0032441
## [869,] 1.1078525
## [870,] 0.9158097
## [871,] 0.9161758
## [872,] 1.0269123
## [873,] 0.8704544
## [874,] 0.9288781
## [875,] 0.8400335
## [876,] 1.0700512
## [877,] 0.9143019
## [878,] 1.1596654
## [879,] 0.8999799
## [880,] 1.0328937
## [881,] 1.0927493
## [882,] 0.8331728
## [883,] 1.2929742
## [884,] 0.9993190
## [885,] 1.1217456
## [886,] 0.9729372
## [887,] 1.1003481
## [888,] 1.1845966
## [889,] 1.1825130
## [890,] 0.9474661
## [891,] 0.8714856
## [892,] 0.8367562
## [893,] 0.8697242
## [894,] 0.8290351
## [895,] 1.1645174
## [896,] 0.8130064
## [897,] 0.9660601
## [898,] 1.1665261
## [899,] 0.8872230
## [900,] 0.9259104
## [901,] 1.0247238
## [902,] 1.0220035
## [903,] 1.0906704
## [904,] 0.8026500
## [905,] 0.8303402
## [906,] 1.0165876
## [907,] 1.0451235
## [908,] 0.9797119
## [909,] 0.9043218
## [910,] 0.8080948
## [911,] 0.9652555
## [912,] 0.7896322
## [913,] 1.3307560
## [914,] 1.0028132
## [915,] 0.7233279
## [916,] 1.1356117
## [917,] 0.8394916
## [918,] 1.1054935
## [919,] 0.8303645
## [920,] 1.0987055
## [921,] 1.0111098
## [922,] 1.1777949
## [923,] 1.1916271
## [924,] 1.0585589
## [925,] 1.3491950
## [926,] 0.7684001
## [927,] 0.8570969
## [928,] 1.0550792
## [929,] 0.9467386
## [930,] 0.7908884
## [931,] 1.0947918
## [932,] 1.0607974
## [933,] 1.0796516
## [934,] 1.0865522
## [935,] 0.9813184
## [936,] 0.9300836
## [937,] 1.1825470
## [938,] 0.8671662
## [939,] 0.9945184
## [940,] 0.9551000
## [941,] 0.8450715
## [942,] 0.9051715
## [943,] 0.8625268
## [944,] 1.0164836
## [945,] 0.8731855
## [946,] 0.9175499
## [947,] 0.8463470
## [948,] 0.9308764
## [949,] 0.9038918
## [950,] 1.0479641
## [951,] 0.9566081
## [952,] 0.9028996
## [953,] 1.0834673
## [954,] 1.0932699
## [955,] 0.9355111
## [956,] 1.0053550
## [957,] 0.6773795
## [958,] 0.9766311
## [959,] 0.9798689
## [960,] 0.9889316
## [961,] 0.7254926
## [962,] 1.0189395
## [963,] 0.9555691
## [964,] 1.2441626
## [965,] 1.1807358
## [966,] 1.1107956
## [967,] 1.1116892
## [968,] 1.1244345
## [969,] 0.8485504
## [970,] 0.9348211
## [971,] 0.8858040
## [972,] 1.1979661
## [973,] 0.8471685
## [974,] 0.8656610
## [975,] 1.0294702
## [976,] 1.0542649
## [977,] 0.8390960
## [978,] 0.9979691
## [979,] 0.9455027
## [980,] 1.0932276
## [981,] 0.9771701
## [982,] 0.8736127
## [983,] 0.9115851
## [984,] 0.9220111
## [985,] 1.0221142
## [986,] 1.1954322
## [987,] 0.9960520
## [988,] 1.0386198
## [989,] 0.8268104
## [990,] 0.9219867
## [991,] 0.7632419
## [992,] 0.6925598
## [993,] 1.0348600
## [994,] 1.1277736
## [995,] 0.7778288
## [996,] 1.0088966
## [997,] 1.0846182
## [998,] 1.1396940
## [999,] 0.9389285
##
## $model.matrix
## (Intercept)
## FengQ_2015.metaphlan_bugs_list.stool:SID31004 1
## FengQ_2015.metaphlan_bugs_list.stool:SID31009 1
## FengQ_2015.metaphlan_bugs_list.stool:SID31021 1
## FengQ_2015.metaphlan_bugs_list.stool:SID31071 1
## FengQ_2015.metaphlan_bugs_list.stool:SID31112 1
## FengQ_2015.metaphlan_bugs_list.stool:SID31129 1
## FengQ_2015.metaphlan_bugs_list.stool:SID31159 1
## FengQ_2015.metaphlan_bugs_list.stool:SID31160 1
## FengQ_2015.metaphlan_bugs_list.stool:SID31188 1
## FengQ_2015.metaphlan_bugs_list.stool:SID31219 1
## FengQ_2015.metaphlan_bugs_list.stool:SID31223 1
## FengQ_2015.metaphlan_bugs_list.stool:SID31236 1
## FengQ_2015.metaphlan_bugs_list.stool:SID31237 1
## FengQ_2015.metaphlan_bugs_list.stool:SID31267 1
## FengQ_2015.metaphlan_bugs_list.stool:SID31276 1
## FengQ_2015.metaphlan_bugs_list.stool:SID31285 1
## FengQ_2015.metaphlan_bugs_list.stool:SID31300 1
## FengQ_2015.metaphlan_bugs_list.stool:SID31328 1
## FengQ_2015.metaphlan_bugs_list.stool:SID31333 1
## FengQ_2015.metaphlan_bugs_list.stool:SID31343 1
## FengQ_2015.metaphlan_bugs_list.stool:SID31360 1
## FengQ_2015.metaphlan_bugs_list.stool:SID31367 1
## FengQ_2015.metaphlan_bugs_list.stool:SID31379 1
## FengQ_2015.metaphlan_bugs_list.stool:SID31416 1
## FengQ_2015.metaphlan_bugs_list.stool:SID31428 1
## FengQ_2015.metaphlan_bugs_list.stool:SID31446 1
## FengQ_2015.metaphlan_bugs_list.stool:SID31450 1
## FengQ_2015.metaphlan_bugs_list.stool:SID31452 1
## FengQ_2015.metaphlan_bugs_list.stool:SID31489 1
## FengQ_2015.metaphlan_bugs_list.stool:SID31493 1
## FengQ_2015.metaphlan_bugs_list.stool:SID31512 1
## FengQ_2015.metaphlan_bugs_list.stool:SID31519 1
## FengQ_2015.metaphlan_bugs_list.stool:SID31537 1
## FengQ_2015.metaphlan_bugs_list.stool:SID31549 1
## FengQ_2015.metaphlan_bugs_list.stool:SID31557 1
## FengQ_2015.metaphlan_bugs_list.stool:SID31637 1
## FengQ_2015.metaphlan_bugs_list.stool:SID31685 1
## FengQ_2015.metaphlan_bugs_list.stool:SID31700 1
## FengQ_2015.metaphlan_bugs_list.stool:SID31711 1
## FengQ_2015.metaphlan_bugs_list.stool:SID31714 1
## FengQ_2015.metaphlan_bugs_list.stool:SID31723 1
## FengQ_2015.metaphlan_bugs_list.stool:SID31749 1
## FengQ_2015.metaphlan_bugs_list.stool:SID31750 1
## FengQ_2015.metaphlan_bugs_list.stool:SID31766 1
## FengQ_2015.metaphlan_bugs_list.stool:SID31865 1
## FengQ_2015.metaphlan_bugs_list.stool:SID31866 1
## FengQ_2015.metaphlan_bugs_list.stool:SID31868 1
## FengQ_2015.metaphlan_bugs_list.stool:SID31870 1
## FengQ_2015.metaphlan_bugs_list.stool:SID31871 1
## FengQ_2015.metaphlan_bugs_list.stool:SID31872 1
## FengQ_2015.metaphlan_bugs_list.stool:SID31873 1
## FengQ_2015.metaphlan_bugs_list.stool:SID31874 1
## FengQ_2015.metaphlan_bugs_list.stool:SID31875 1
## FengQ_2015.metaphlan_bugs_list.stool:SID31876 1
## FengQ_2015.metaphlan_bugs_list.stool:SID31877 1
## FengQ_2015.metaphlan_bugs_list.stool:SID31878 1
## FengQ_2015.metaphlan_bugs_list.stool:SID31879 1
## FengQ_2015.metaphlan_bugs_list.stool:SID31880 1
## FengQ_2015.metaphlan_bugs_list.stool:SID31881 1
## FengQ_2015.metaphlan_bugs_list.stool:SID31883 1
## FengQ_2015.metaphlan_bugs_list.stool:SID31884 1
## FengQ_2015.metaphlan_bugs_list.stool:SID530050 1
## FengQ_2015.metaphlan_bugs_list.stool:SID530052 1
## FengQ_2015.metaphlan_bugs_list.stool:SID530055 1
## FengQ_2015.metaphlan_bugs_list.stool:SID530074 1
## FengQ_2015.metaphlan_bugs_list.stool:SID530075 1
## FengQ_2015.metaphlan_bugs_list.stool:SID530119 1
## FengQ_2015.metaphlan_bugs_list.stool:SID530154 1
## FengQ_2015.metaphlan_bugs_list.stool:SID530163 1
## FengQ_2015.metaphlan_bugs_list.stool:SID530167 1
## FengQ_2015.metaphlan_bugs_list.stool:SID530177 1
## FengQ_2015.metaphlan_bugs_list.stool:SID530215 1
## FengQ_2015.metaphlan_bugs_list.stool:SID530227 1
## FengQ_2015.metaphlan_bugs_list.stool:SID530251 1
## FengQ_2015.metaphlan_bugs_list.stool:SID530258 1
## FengQ_2015.metaphlan_bugs_list.stool:SID530295 1
## FengQ_2015.metaphlan_bugs_list.stool:SID530315 1
## FengQ_2015.metaphlan_bugs_list.stool:SID530331 1
## FengQ_2015.metaphlan_bugs_list.stool:SID530364 1
## FengQ_2015.metaphlan_bugs_list.stool:SID530368 1
## FengQ_2015.metaphlan_bugs_list.stool:SID530373 1
## FengQ_2015.metaphlan_bugs_list.stool:SID530394 1
## FengQ_2015.metaphlan_bugs_list.stool:SID530444 1
## FengQ_2015.metaphlan_bugs_list.stool:SID530451 1
## FengQ_2015.metaphlan_bugs_list.stool:SID530890 1
## FengQ_2015.metaphlan_bugs_list.stool:SID531128 1
## FengQ_2015.metaphlan_bugs_list.stool:SID531155 1
## FengQ_2015.metaphlan_bugs_list.stool:SID531248 1
## FengQ_2015.metaphlan_bugs_list.stool:SID531274 1
## FengQ_2015.metaphlan_bugs_list.stool:SID531277 1
## FengQ_2015.metaphlan_bugs_list.stool:SID531281 1
## FengQ_2015.metaphlan_bugs_list.stool:SID531333 1
## FengQ_2015.metaphlan_bugs_list.stool:SID531352 1
## FengQ_2015.metaphlan_bugs_list.stool:SID531361 1
## FengQ_2015.metaphlan_bugs_list.stool:SID531382 1
## FengQ_2015.metaphlan_bugs_list.stool:SID531414 1
## FengQ_2015.metaphlan_bugs_list.stool:SID531416 1
## FengQ_2015.metaphlan_bugs_list.stool:SID531424 1
## FengQ_2015.metaphlan_bugs_list.stool:SID531469 1
## FengQ_2015.metaphlan_bugs_list.stool:SID531766 1
## FengQ_2015.metaphlan_bugs_list.stool:SID531775 1
## FengQ_2015.metaphlan_bugs_list.stool:SID532749 1
## FengQ_2015.metaphlan_bugs_list.stool:SID532779 1
## FengQ_2015.metaphlan_bugs_list.stool:SID532796 1
## FengQ_2015.metaphlan_bugs_list.stool:SID532802 1
## FengQ_2015.metaphlan_bugs_list.stool:SID532826 1
## FengQ_2015.metaphlan_bugs_list.stool:SID532915 1
## HanniganGD_2017.metaphlan_bugs_list.stool:MG100180 1
## HanniganGD_2017.metaphlan_bugs_list.stool:MG100179 1
## HanniganGD_2017.metaphlan_bugs_list.stool:MG100178 1
## HanniganGD_2017.metaphlan_bugs_list.stool:MG100177 1
## HanniganGD_2017.metaphlan_bugs_list.stool:MG100176 1
## HanniganGD_2017.metaphlan_bugs_list.stool:MG100175 1
## HanniganGD_2017.metaphlan_bugs_list.stool:MG100174 1
## HanniganGD_2017.metaphlan_bugs_list.stool:MG100173 1
## HanniganGD_2017.metaphlan_bugs_list.stool:MG100172 1
## HanniganGD_2017.metaphlan_bugs_list.stool:MG100171 1
## HanniganGD_2017.metaphlan_bugs_list.stool:MG100170 1
## HanniganGD_2017.metaphlan_bugs_list.stool:MG100169 1
## HanniganGD_2017.metaphlan_bugs_list.stool:MG100168 1
## HanniganGD_2017.metaphlan_bugs_list.stool:MG100167 1
## HanniganGD_2017.metaphlan_bugs_list.stool:MG100166 1
## HanniganGD_2017.metaphlan_bugs_list.stool:MG100165 1
## HanniganGD_2017.metaphlan_bugs_list.stool:MG100164 1
## HanniganGD_2017.metaphlan_bugs_list.stool:MG100163 1
## HanniganGD_2017.metaphlan_bugs_list.stool:MG100162 1
## HanniganGD_2017.metaphlan_bugs_list.stool:MG100161 1
## HanniganGD_2017.metaphlan_bugs_list.stool:MG100160 1
## HanniganGD_2017.metaphlan_bugs_list.stool:MG100159 1
## HanniganGD_2017.metaphlan_bugs_list.stool:MG100158 1
## HanniganGD_2017.metaphlan_bugs_list.stool:MG100157 1
## HanniganGD_2017.metaphlan_bugs_list.stool:MG100156 1
## HanniganGD_2017.metaphlan_bugs_list.stool:MG100155 1
## HanniganGD_2017.metaphlan_bugs_list.stool:MG100154 1
## HanniganGD_2017.metaphlan_bugs_list.stool:MG100153 1
## HanniganGD_2017.metaphlan_bugs_list.stool:MG100152 1
## HanniganGD_2017.metaphlan_bugs_list.stool:MG100151 1
## HanniganGD_2017.metaphlan_bugs_list.stool:MG100150 1
## HanniganGD_2017.metaphlan_bugs_list.stool:MG100149 1
## HanniganGD_2017.metaphlan_bugs_list.stool:MG100148 1
## HanniganGD_2017.metaphlan_bugs_list.stool:MG100147 1
## HanniganGD_2017.metaphlan_bugs_list.stool:MG100146 1
## HanniganGD_2017.metaphlan_bugs_list.stool:MG100145 1
## HanniganGD_2017.metaphlan_bugs_list.stool:MG100144 1
## HanniganGD_2017.metaphlan_bugs_list.stool:MG100143 1
## HanniganGD_2017.metaphlan_bugs_list.stool:MG100142 1
## HanniganGD_2017.metaphlan_bugs_list.stool:MG100141 1
## HanniganGD_2017.metaphlan_bugs_list.stool:MG100140 1
## HanniganGD_2017.metaphlan_bugs_list.stool:MG100139 1
## HanniganGD_2017.metaphlan_bugs_list.stool:MG100138 1
## HanniganGD_2017.metaphlan_bugs_list.stool:MG100137 1
## HanniganGD_2017.metaphlan_bugs_list.stool:MG100136 1
## HanniganGD_2017.metaphlan_bugs_list.stool:MG100134 1
## HanniganGD_2017.metaphlan_bugs_list.stool:MG100133 1
## HanniganGD_2017.metaphlan_bugs_list.stool:MG100132 1
## HanniganGD_2017.metaphlan_bugs_list.stool:MG100131 1
## HanniganGD_2017.metaphlan_bugs_list.stool:MG100130 1
## HanniganGD_2017.metaphlan_bugs_list.stool:MG100129 1
## HanniganGD_2017.metaphlan_bugs_list.stool:MG100128 1
## HanniganGD_2017.metaphlan_bugs_list.stool:MG100127 1
## HanniganGD_2017.metaphlan_bugs_list.stool:MG100126 1
## HanniganGD_2017.metaphlan_bugs_list.stool:MG100125 1
## VogtmannE_2016.metaphlan_bugs_list.stool:MMRS11288076ST-27-0-0 1
## VogtmannE_2016.metaphlan_bugs_list.stool:MMRS11932626ST-27-0-0 1
## VogtmannE_2016.metaphlan_bugs_list.stool:MMRS12272136ST-27-0-0 1
## VogtmannE_2016.metaphlan_bugs_list.stool:MMRS14379078ST-27-0-0 1
## VogtmannE_2016.metaphlan_bugs_list.stool:MMRS14602194ST-27-0-0 1
## VogtmannE_2016.metaphlan_bugs_list.stool:MMRS15137911ST-27-0-0 1
## VogtmannE_2016.metaphlan_bugs_list.stool:MMRS16644320ST-27-0-0 1
## VogtmannE_2016.metaphlan_bugs_list.stool:MMRS17603756ST-27-0-0 1
## VogtmannE_2016.metaphlan_bugs_list.stool:MMRS17963147ST-27-0-0 1
## VogtmannE_2016.metaphlan_bugs_list.stool:MMRS18295921ST-27-0-0 1
## VogtmannE_2016.metaphlan_bugs_list.stool:MMRS20257302ST-27-0-0 1
## VogtmannE_2016.metaphlan_bugs_list.stool:MMRS21365932ST-27-0-0 1
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## ZellerG_2014.metaphlan_bugs_list.stool:CCIS36797902ST-4-0 1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS38765456ST-20-0 1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS40244499ST-3-0 1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS41222843ST-4-0 1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS41288781ST-4-0 1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS41548810ST-4-0 1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS41692898ST-4-0 1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS44093303ST-4-0 1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS44757994ST-4-0 1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS45571137ST-3-0 1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS45793747ST-4-0 1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS46047672ST-4-0 1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS46467422ST-4-0 1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS47284573ST-4-0 1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS48174381ST-4-0 1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS48725289ST-4-0 1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS50003399ST-4-0 1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS50148151ST-4-0 1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS50471204ST-4-0 1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS51595129ST-4-0 1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS52370277ST-4-0 1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS53043478ST-4-0 1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS53355328ST-4-0 1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS55230578ST-4-0 1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS58234805ST-4-0 1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS59132091ST-4-0 1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS61287323ST-4-0 1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS62605362ST-3-0 1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS62794166ST-4-0 1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS63448910ST-4-0 1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS63468405ST-4-0 1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS63910149ST-4-0 1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS64773582ST-4-0 1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS64785924ST-20-0 1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS65479369ST-4-0 1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS71301801ST-4-0 1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS71578391ST-4-0 1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS72607085ST-4-0 1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS74239020ST-4-0 1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS76845094ST-20-0 1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS77252613ST-4-0 1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS78100604ST-4-0 1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS78318719ST-4-0 1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS79210440ST-3-0 1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS80834637ST-4-0 1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS81139242ST-4-0 1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS81887263ST-4-0 1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS82146115ST-4-0 1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS82507866ST-3-0 1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS82944710ST-20-0 1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS83870198ST-4-0 1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS84543192ST-4-0 1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS85214191ST-3-0 1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS87116798ST-4-0 1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS87167916ST-4-0 1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS87252800ST-4-0 1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS87605453ST-4-0 1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS88007743ST-4-0 1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS88317640ST-4-0 1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS90164298ST-4-0 1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS91228662ST-4-0 1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS93040568ST-20-0 1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS94417875ST-3-0 1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS94603952ST-4-0 1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS95097901ST-4-0 1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS95409808ST-4-0 1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS98482370ST-3-0 1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS98512455ST-4-0 1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS98832363ST-4-0 1
## ZellerG_2014.metaphlan_bugs_list.stool:CCMD11006829ST-21-0 1
## ZellerG_2014.metaphlan_bugs_list.stool:CCMD12232071ST-21-0 1
## ZellerG_2014.metaphlan_bugs_list.stool:CCMD13071240ST-21-0 1
## ZellerG_2014.metaphlan_bugs_list.stool:CCMD13934959ST-21-0 1
## ZellerG_2014.metaphlan_bugs_list.stool:CCMD14479708ST-21-0 1
## ZellerG_2014.metaphlan_bugs_list.stool:CCMD18872694ST-21-0 1
## ZellerG_2014.metaphlan_bugs_list.stool:CCMD19497912ST-21-0 1
## ZellerG_2014.metaphlan_bugs_list.stool:CCMD23101338ST-21-0 1
## ZellerG_2014.metaphlan_bugs_list.stool:CCMD25511638ST-21-0 1
## ZellerG_2014.metaphlan_bugs_list.stool:CCMD25963797ST-21-0 1
## ZellerG_2014.metaphlan_bugs_list.stool:CCMD26709089ST-21-0 1
## ZellerG_2014.metaphlan_bugs_list.stool:CCMD26925580ST-21-0 1
## ZellerG_2014.metaphlan_bugs_list.stool:CCMD34381688ST-21-0 1
## ZellerG_2014.metaphlan_bugs_list.stool:CCMD35802077ST-21-0 1
## ZellerG_2014.metaphlan_bugs_list.stool:CCMD40701343ST-21-0 1
## ZellerG_2014.metaphlan_bugs_list.stool:CCMD42428553ST-21-0 1
## ZellerG_2014.metaphlan_bugs_list.stool:CCMD45988061ST-21-0 1
## ZellerG_2014.metaphlan_bugs_list.stool:CCMD46222674ST-21-0 1
## ZellerG_2014.metaphlan_bugs_list.stool:CCMD46947453ST-21-0 1
## ZellerG_2014.metaphlan_bugs_list.stool:CCMD48236717ST-21-0 1
## ZellerG_2014.metaphlan_bugs_list.stool:CCMD50071957ST-21-0 1
## ZellerG_2014.metaphlan_bugs_list.stool:CCMD51864103ST-21-0 1
## ZellerG_2014.metaphlan_bugs_list.stool:CCMD60079086ST-21-0 1
## ZellerG_2014.metaphlan_bugs_list.stool:CCMD63399960ST-21-0 1
## ZellerG_2014.metaphlan_bugs_list.stool:CCMD64503764ST-21-0 1
## ZellerG_2014.metaphlan_bugs_list.stool:CCMD64776337ST-21-0 1
## ZellerG_2014.metaphlan_bugs_list.stool:CCMD72895164ST-21-0 1
## ZellerG_2014.metaphlan_bugs_list.stool:CCMD74930188ST-21-0 1
## ZellerG_2014.metaphlan_bugs_list.stool:CCMD79987997ST-21-0 1
## ZellerG_2014.metaphlan_bugs_list.stool:CCMD82866709ST-21-0 1
## ZellerG_2014.metaphlan_bugs_list.stool:CCMD86114146ST-21-0 1
## ZellerG_2014.metaphlan_bugs_list.stool:CCMD86707194ST-21-0 1
## ZellerG_2014.metaphlan_bugs_list.stool:CCMD87156761ST-21-0 1
## ZellerG_2014.metaphlan_bugs_list.stool:CCMD88272491ST-21-0 1
## ZellerG_2014.metaphlan_bugs_list.stool:CCMD90311071ST-21-0 1
## ZellerG_2014.metaphlan_bugs_list.stool:CCMD93344354ST-21-0 1
## ZellerG_2014.metaphlan_bugs_list.stool:CCMD95433940ST-21-0 1
## ZellerG_2014.metaphlan_bugs_list.stool:CCMD96553385ST-21-0 1
## ZellerG_2014.metaphlan_bugs_list.stool:MMPU29365221ST 1
## ZellerG_2014.metaphlan_bugs_list.stool:MMPU68403337ST 1
## ZellerG_2014.metaphlan_bugs_list.stool:MMPU72854103ST 1
## ZellerG_2014.metaphlan_bugs_list.stool:MMPU84450604ST 1
## ZellerG_2014.metaphlan_bugs_list.stool:MMPU99077057ST 1
## studyID1
## FengQ_2015.metaphlan_bugs_list.stool:SID31004 1
## FengQ_2015.metaphlan_bugs_list.stool:SID31009 1
## FengQ_2015.metaphlan_bugs_list.stool:SID31021 1
## FengQ_2015.metaphlan_bugs_list.stool:SID31071 1
## FengQ_2015.metaphlan_bugs_list.stool:SID31112 1
## FengQ_2015.metaphlan_bugs_list.stool:SID31129 1
## FengQ_2015.metaphlan_bugs_list.stool:SID31159 1
## FengQ_2015.metaphlan_bugs_list.stool:SID31160 1
## FengQ_2015.metaphlan_bugs_list.stool:SID31188 1
## FengQ_2015.metaphlan_bugs_list.stool:SID31219 1
## FengQ_2015.metaphlan_bugs_list.stool:SID31223 1
## FengQ_2015.metaphlan_bugs_list.stool:SID31236 1
## FengQ_2015.metaphlan_bugs_list.stool:SID31237 1
## FengQ_2015.metaphlan_bugs_list.stool:SID31267 1
## FengQ_2015.metaphlan_bugs_list.stool:SID31276 1
## FengQ_2015.metaphlan_bugs_list.stool:SID31285 1
## FengQ_2015.metaphlan_bugs_list.stool:SID31300 1
## FengQ_2015.metaphlan_bugs_list.stool:SID31328 1
## FengQ_2015.metaphlan_bugs_list.stool:SID31333 1
## FengQ_2015.metaphlan_bugs_list.stool:SID31343 1
## FengQ_2015.metaphlan_bugs_list.stool:SID31360 1
## FengQ_2015.metaphlan_bugs_list.stool:SID31367 1
## FengQ_2015.metaphlan_bugs_list.stool:SID31379 1
## FengQ_2015.metaphlan_bugs_list.stool:SID31416 1
## FengQ_2015.metaphlan_bugs_list.stool:SID31428 1
## FengQ_2015.metaphlan_bugs_list.stool:SID31446 1
## FengQ_2015.metaphlan_bugs_list.stool:SID31450 1
## FengQ_2015.metaphlan_bugs_list.stool:SID31452 1
## FengQ_2015.metaphlan_bugs_list.stool:SID31489 1
## FengQ_2015.metaphlan_bugs_list.stool:SID31493 1
## FengQ_2015.metaphlan_bugs_list.stool:SID31512 1
## FengQ_2015.metaphlan_bugs_list.stool:SID31519 1
## FengQ_2015.metaphlan_bugs_list.stool:SID31537 1
## FengQ_2015.metaphlan_bugs_list.stool:SID31549 1
## FengQ_2015.metaphlan_bugs_list.stool:SID31557 1
## FengQ_2015.metaphlan_bugs_list.stool:SID31637 1
## FengQ_2015.metaphlan_bugs_list.stool:SID31685 1
## FengQ_2015.metaphlan_bugs_list.stool:SID31700 1
## FengQ_2015.metaphlan_bugs_list.stool:SID31711 1
## FengQ_2015.metaphlan_bugs_list.stool:SID31714 1
## FengQ_2015.metaphlan_bugs_list.stool:SID31723 1
## FengQ_2015.metaphlan_bugs_list.stool:SID31749 1
## FengQ_2015.metaphlan_bugs_list.stool:SID31750 1
## FengQ_2015.metaphlan_bugs_list.stool:SID31766 1
## FengQ_2015.metaphlan_bugs_list.stool:SID31865 1
## FengQ_2015.metaphlan_bugs_list.stool:SID31866 1
## FengQ_2015.metaphlan_bugs_list.stool:SID31868 1
## FengQ_2015.metaphlan_bugs_list.stool:SID31870 1
## FengQ_2015.metaphlan_bugs_list.stool:SID31871 1
## FengQ_2015.metaphlan_bugs_list.stool:SID31872 1
## FengQ_2015.metaphlan_bugs_list.stool:SID31873 1
## FengQ_2015.metaphlan_bugs_list.stool:SID31874 1
## FengQ_2015.metaphlan_bugs_list.stool:SID31875 1
## FengQ_2015.metaphlan_bugs_list.stool:SID31876 1
## FengQ_2015.metaphlan_bugs_list.stool:SID31877 1
## FengQ_2015.metaphlan_bugs_list.stool:SID31878 1
## FengQ_2015.metaphlan_bugs_list.stool:SID31879 1
## FengQ_2015.metaphlan_bugs_list.stool:SID31880 1
## FengQ_2015.metaphlan_bugs_list.stool:SID31881 1
## FengQ_2015.metaphlan_bugs_list.stool:SID31883 1
## FengQ_2015.metaphlan_bugs_list.stool:SID31884 1
## FengQ_2015.metaphlan_bugs_list.stool:SID530050 1
## FengQ_2015.metaphlan_bugs_list.stool:SID530052 1
## FengQ_2015.metaphlan_bugs_list.stool:SID530055 1
## FengQ_2015.metaphlan_bugs_list.stool:SID530074 1
## FengQ_2015.metaphlan_bugs_list.stool:SID530075 1
## FengQ_2015.metaphlan_bugs_list.stool:SID530119 1
## FengQ_2015.metaphlan_bugs_list.stool:SID530154 1
## FengQ_2015.metaphlan_bugs_list.stool:SID530163 1
## FengQ_2015.metaphlan_bugs_list.stool:SID530167 1
## FengQ_2015.metaphlan_bugs_list.stool:SID530177 1
## FengQ_2015.metaphlan_bugs_list.stool:SID530215 1
## FengQ_2015.metaphlan_bugs_list.stool:SID530227 1
## FengQ_2015.metaphlan_bugs_list.stool:SID530251 1
## FengQ_2015.metaphlan_bugs_list.stool:SID530258 1
## FengQ_2015.metaphlan_bugs_list.stool:SID530295 1
## FengQ_2015.metaphlan_bugs_list.stool:SID530315 1
## FengQ_2015.metaphlan_bugs_list.stool:SID530331 1
## FengQ_2015.metaphlan_bugs_list.stool:SID530364 1
## FengQ_2015.metaphlan_bugs_list.stool:SID530368 1
## FengQ_2015.metaphlan_bugs_list.stool:SID530373 1
## FengQ_2015.metaphlan_bugs_list.stool:SID530394 1
## FengQ_2015.metaphlan_bugs_list.stool:SID530444 1
## FengQ_2015.metaphlan_bugs_list.stool:SID530451 1
## FengQ_2015.metaphlan_bugs_list.stool:SID530890 1
## FengQ_2015.metaphlan_bugs_list.stool:SID531128 1
## FengQ_2015.metaphlan_bugs_list.stool:SID531155 1
## FengQ_2015.metaphlan_bugs_list.stool:SID531248 1
## FengQ_2015.metaphlan_bugs_list.stool:SID531274 1
## FengQ_2015.metaphlan_bugs_list.stool:SID531277 1
## FengQ_2015.metaphlan_bugs_list.stool:SID531281 1
## FengQ_2015.metaphlan_bugs_list.stool:SID531333 1
## FengQ_2015.metaphlan_bugs_list.stool:SID531352 1
## FengQ_2015.metaphlan_bugs_list.stool:SID531361 1
## FengQ_2015.metaphlan_bugs_list.stool:SID531382 1
## FengQ_2015.metaphlan_bugs_list.stool:SID531414 1
## FengQ_2015.metaphlan_bugs_list.stool:SID531416 1
## FengQ_2015.metaphlan_bugs_list.stool:SID531424 1
## FengQ_2015.metaphlan_bugs_list.stool:SID531469 1
## FengQ_2015.metaphlan_bugs_list.stool:SID531766 1
## FengQ_2015.metaphlan_bugs_list.stool:SID531775 1
## FengQ_2015.metaphlan_bugs_list.stool:SID532749 1
## FengQ_2015.metaphlan_bugs_list.stool:SID532779 1
## FengQ_2015.metaphlan_bugs_list.stool:SID532796 1
## FengQ_2015.metaphlan_bugs_list.stool:SID532802 1
## FengQ_2015.metaphlan_bugs_list.stool:SID532826 1
## FengQ_2015.metaphlan_bugs_list.stool:SID532915 1
## HanniganGD_2017.metaphlan_bugs_list.stool:MG100180 0
## HanniganGD_2017.metaphlan_bugs_list.stool:MG100179 0
## HanniganGD_2017.metaphlan_bugs_list.stool:MG100178 0
## HanniganGD_2017.metaphlan_bugs_list.stool:MG100177 0
## HanniganGD_2017.metaphlan_bugs_list.stool:MG100176 0
## HanniganGD_2017.metaphlan_bugs_list.stool:MG100175 0
## HanniganGD_2017.metaphlan_bugs_list.stool:MG100174 0
## HanniganGD_2017.metaphlan_bugs_list.stool:MG100173 0
## HanniganGD_2017.metaphlan_bugs_list.stool:MG100172 0
## HanniganGD_2017.metaphlan_bugs_list.stool:MG100171 0
## HanniganGD_2017.metaphlan_bugs_list.stool:MG100170 0
## HanniganGD_2017.metaphlan_bugs_list.stool:MG100169 0
## HanniganGD_2017.metaphlan_bugs_list.stool:MG100168 0
## HanniganGD_2017.metaphlan_bugs_list.stool:MG100167 0
## HanniganGD_2017.metaphlan_bugs_list.stool:MG100166 0
## HanniganGD_2017.metaphlan_bugs_list.stool:MG100165 0
## HanniganGD_2017.metaphlan_bugs_list.stool:MG100164 0
## HanniganGD_2017.metaphlan_bugs_list.stool:MG100163 0
## HanniganGD_2017.metaphlan_bugs_list.stool:MG100162 0
## HanniganGD_2017.metaphlan_bugs_list.stool:MG100161 0
## HanniganGD_2017.metaphlan_bugs_list.stool:MG100160 0
## HanniganGD_2017.metaphlan_bugs_list.stool:MG100159 0
## HanniganGD_2017.metaphlan_bugs_list.stool:MG100158 0
## HanniganGD_2017.metaphlan_bugs_list.stool:MG100157 0
## HanniganGD_2017.metaphlan_bugs_list.stool:MG100156 0
## HanniganGD_2017.metaphlan_bugs_list.stool:MG100155 0
## HanniganGD_2017.metaphlan_bugs_list.stool:MG100154 0
## HanniganGD_2017.metaphlan_bugs_list.stool:MG100153 0
## HanniganGD_2017.metaphlan_bugs_list.stool:MG100152 0
## HanniganGD_2017.metaphlan_bugs_list.stool:MG100151 0
## HanniganGD_2017.metaphlan_bugs_list.stool:MG100150 0
## HanniganGD_2017.metaphlan_bugs_list.stool:MG100149 0
## HanniganGD_2017.metaphlan_bugs_list.stool:MG100148 0
## HanniganGD_2017.metaphlan_bugs_list.stool:MG100147 0
## HanniganGD_2017.metaphlan_bugs_list.stool:MG100146 0
## HanniganGD_2017.metaphlan_bugs_list.stool:MG100145 0
## HanniganGD_2017.metaphlan_bugs_list.stool:MG100144 0
## HanniganGD_2017.metaphlan_bugs_list.stool:MG100143 0
## HanniganGD_2017.metaphlan_bugs_list.stool:MG100142 0
## HanniganGD_2017.metaphlan_bugs_list.stool:MG100141 0
## HanniganGD_2017.metaphlan_bugs_list.stool:MG100140 0
## HanniganGD_2017.metaphlan_bugs_list.stool:MG100139 0
## HanniganGD_2017.metaphlan_bugs_list.stool:MG100138 0
## HanniganGD_2017.metaphlan_bugs_list.stool:MG100137 0
## HanniganGD_2017.metaphlan_bugs_list.stool:MG100136 0
## HanniganGD_2017.metaphlan_bugs_list.stool:MG100134 0
## HanniganGD_2017.metaphlan_bugs_list.stool:MG100133 0
## HanniganGD_2017.metaphlan_bugs_list.stool:MG100132 0
## HanniganGD_2017.metaphlan_bugs_list.stool:MG100131 0
## HanniganGD_2017.metaphlan_bugs_list.stool:MG100130 0
## HanniganGD_2017.metaphlan_bugs_list.stool:MG100129 0
## HanniganGD_2017.metaphlan_bugs_list.stool:MG100128 0
## HanniganGD_2017.metaphlan_bugs_list.stool:MG100127 0
## HanniganGD_2017.metaphlan_bugs_list.stool:MG100126 0
## HanniganGD_2017.metaphlan_bugs_list.stool:MG100125 0
## VogtmannE_2016.metaphlan_bugs_list.stool:MMRS11288076ST-27-0-0 0
## VogtmannE_2016.metaphlan_bugs_list.stool:MMRS11932626ST-27-0-0 0
## VogtmannE_2016.metaphlan_bugs_list.stool:MMRS12272136ST-27-0-0 0
## VogtmannE_2016.metaphlan_bugs_list.stool:MMRS14379078ST-27-0-0 0
## VogtmannE_2016.metaphlan_bugs_list.stool:MMRS14602194ST-27-0-0 0
## VogtmannE_2016.metaphlan_bugs_list.stool:MMRS15137911ST-27-0-0 0
## VogtmannE_2016.metaphlan_bugs_list.stool:MMRS16644320ST-27-0-0 0
## VogtmannE_2016.metaphlan_bugs_list.stool:MMRS17603756ST-27-0-0 0
## VogtmannE_2016.metaphlan_bugs_list.stool:MMRS17963147ST-27-0-0 0
## VogtmannE_2016.metaphlan_bugs_list.stool:MMRS18295921ST-27-0-0 0
## VogtmannE_2016.metaphlan_bugs_list.stool:MMRS20257302ST-27-0-0 0
## VogtmannE_2016.metaphlan_bugs_list.stool:MMRS21365932ST-27-0-0 0
## VogtmannE_2016.metaphlan_bugs_list.stool:MMRS24340226ST-27-0-0 0
## VogtmannE_2016.metaphlan_bugs_list.stool:MMRS25211151ST-27-0-0 0
## VogtmannE_2016.metaphlan_bugs_list.stool:MMRS25641480ST-27-0-0 0
## VogtmannE_2016.metaphlan_bugs_list.stool:MMRS29805707ST-27-0-0 0
## VogtmannE_2016.metaphlan_bugs_list.stool:MMRS31306426ST-27-0-0 0
## VogtmannE_2016.metaphlan_bugs_list.stool:MMRS32573774ST-27-0-0 0
## VogtmannE_2016.metaphlan_bugs_list.stool:MMRS33294861ST-27-0-0 0
## VogtmannE_2016.metaphlan_bugs_list.stool:MMRS34525504ST-27-0-0 0
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## ZellerG_2014.metaphlan_bugs_list.stool:CCIS44093303ST-4-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS44757994ST-4-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS45571137ST-3-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS45793747ST-4-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS46047672ST-4-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS46467422ST-4-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS47284573ST-4-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS48174381ST-4-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS48725289ST-4-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS50003399ST-4-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS50148151ST-4-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS50471204ST-4-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS51595129ST-4-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS52370277ST-4-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS53043478ST-4-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS53355328ST-4-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS55230578ST-4-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS58234805ST-4-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS59132091ST-4-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS61287323ST-4-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS62605362ST-3-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS62794166ST-4-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS63448910ST-4-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS63468405ST-4-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS63910149ST-4-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS64773582ST-4-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS64785924ST-20-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS65479369ST-4-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS71301801ST-4-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS71578391ST-4-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS72607085ST-4-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS74239020ST-4-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS76845094ST-20-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS77252613ST-4-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS78100604ST-4-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS78318719ST-4-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS79210440ST-3-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS80834637ST-4-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS81139242ST-4-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS81887263ST-4-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS82146115ST-4-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS82507866ST-3-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS82944710ST-20-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS83870198ST-4-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS84543192ST-4-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS85214191ST-3-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS87116798ST-4-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS87167916ST-4-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS87252800ST-4-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS87605453ST-4-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS88007743ST-4-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS88317640ST-4-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS90164298ST-4-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS91228662ST-4-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS93040568ST-20-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS94417875ST-3-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS94603952ST-4-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS95097901ST-4-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS95409808ST-4-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS98482370ST-3-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS98512455ST-4-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS98832363ST-4-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCMD11006829ST-21-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCMD12232071ST-21-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCMD13071240ST-21-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCMD13934959ST-21-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCMD14479708ST-21-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCMD18872694ST-21-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCMD19497912ST-21-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCMD23101338ST-21-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCMD25511638ST-21-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCMD25963797ST-21-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCMD26709089ST-21-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCMD26925580ST-21-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCMD34381688ST-21-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCMD35802077ST-21-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCMD40701343ST-21-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCMD42428553ST-21-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCMD45988061ST-21-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCMD46222674ST-21-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCMD46947453ST-21-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCMD48236717ST-21-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCMD50071957ST-21-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCMD51864103ST-21-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCMD60079086ST-21-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCMD63399960ST-21-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCMD64503764ST-21-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCMD64776337ST-21-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCMD72895164ST-21-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCMD74930188ST-21-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCMD79987997ST-21-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCMD82866709ST-21-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCMD86114146ST-21-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCMD86707194ST-21-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCMD87156761ST-21-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCMD88272491ST-21-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCMD90311071ST-21-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCMD93344354ST-21-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCMD95433940ST-21-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCMD96553385ST-21-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:MMPU29365221ST -1
## ZellerG_2014.metaphlan_bugs_list.stool:MMPU68403337ST -1
## ZellerG_2014.metaphlan_bugs_list.stool:MMPU72854103ST -1
## ZellerG_2014.metaphlan_bugs_list.stool:MMPU84450604ST -1
## ZellerG_2014.metaphlan_bugs_list.stool:MMPU99077057ST -1
## studyID2
## FengQ_2015.metaphlan_bugs_list.stool:SID31004 0
## FengQ_2015.metaphlan_bugs_list.stool:SID31009 0
## FengQ_2015.metaphlan_bugs_list.stool:SID31021 0
## FengQ_2015.metaphlan_bugs_list.stool:SID31071 0
## FengQ_2015.metaphlan_bugs_list.stool:SID31112 0
## FengQ_2015.metaphlan_bugs_list.stool:SID31129 0
## FengQ_2015.metaphlan_bugs_list.stool:SID31159 0
## FengQ_2015.metaphlan_bugs_list.stool:SID31160 0
## FengQ_2015.metaphlan_bugs_list.stool:SID31188 0
## FengQ_2015.metaphlan_bugs_list.stool:SID31219 0
## FengQ_2015.metaphlan_bugs_list.stool:SID31223 0
## FengQ_2015.metaphlan_bugs_list.stool:SID31236 0
## FengQ_2015.metaphlan_bugs_list.stool:SID31237 0
## FengQ_2015.metaphlan_bugs_list.stool:SID31267 0
## FengQ_2015.metaphlan_bugs_list.stool:SID31276 0
## FengQ_2015.metaphlan_bugs_list.stool:SID31285 0
## FengQ_2015.metaphlan_bugs_list.stool:SID31300 0
## FengQ_2015.metaphlan_bugs_list.stool:SID31328 0
## FengQ_2015.metaphlan_bugs_list.stool:SID31333 0
## FengQ_2015.metaphlan_bugs_list.stool:SID31343 0
## FengQ_2015.metaphlan_bugs_list.stool:SID31360 0
## FengQ_2015.metaphlan_bugs_list.stool:SID31367 0
## FengQ_2015.metaphlan_bugs_list.stool:SID31379 0
## FengQ_2015.metaphlan_bugs_list.stool:SID31416 0
## FengQ_2015.metaphlan_bugs_list.stool:SID31428 0
## FengQ_2015.metaphlan_bugs_list.stool:SID31446 0
## FengQ_2015.metaphlan_bugs_list.stool:SID31450 0
## FengQ_2015.metaphlan_bugs_list.stool:SID31452 0
## FengQ_2015.metaphlan_bugs_list.stool:SID31489 0
## FengQ_2015.metaphlan_bugs_list.stool:SID31493 0
## FengQ_2015.metaphlan_bugs_list.stool:SID31512 0
## FengQ_2015.metaphlan_bugs_list.stool:SID31519 0
## FengQ_2015.metaphlan_bugs_list.stool:SID31537 0
## FengQ_2015.metaphlan_bugs_list.stool:SID31549 0
## FengQ_2015.metaphlan_bugs_list.stool:SID31557 0
## FengQ_2015.metaphlan_bugs_list.stool:SID31637 0
## FengQ_2015.metaphlan_bugs_list.stool:SID31685 0
## FengQ_2015.metaphlan_bugs_list.stool:SID31700 0
## FengQ_2015.metaphlan_bugs_list.stool:SID31711 0
## FengQ_2015.metaphlan_bugs_list.stool:SID31714 0
## FengQ_2015.metaphlan_bugs_list.stool:SID31723 0
## FengQ_2015.metaphlan_bugs_list.stool:SID31749 0
## FengQ_2015.metaphlan_bugs_list.stool:SID31750 0
## FengQ_2015.metaphlan_bugs_list.stool:SID31766 0
## FengQ_2015.metaphlan_bugs_list.stool:SID31865 0
## FengQ_2015.metaphlan_bugs_list.stool:SID31866 0
## FengQ_2015.metaphlan_bugs_list.stool:SID31868 0
## FengQ_2015.metaphlan_bugs_list.stool:SID31870 0
## FengQ_2015.metaphlan_bugs_list.stool:SID31871 0
## FengQ_2015.metaphlan_bugs_list.stool:SID31872 0
## FengQ_2015.metaphlan_bugs_list.stool:SID31873 0
## FengQ_2015.metaphlan_bugs_list.stool:SID31874 0
## FengQ_2015.metaphlan_bugs_list.stool:SID31875 0
## FengQ_2015.metaphlan_bugs_list.stool:SID31876 0
## FengQ_2015.metaphlan_bugs_list.stool:SID31877 0
## FengQ_2015.metaphlan_bugs_list.stool:SID31878 0
## FengQ_2015.metaphlan_bugs_list.stool:SID31879 0
## FengQ_2015.metaphlan_bugs_list.stool:SID31880 0
## FengQ_2015.metaphlan_bugs_list.stool:SID31881 0
## FengQ_2015.metaphlan_bugs_list.stool:SID31883 0
## FengQ_2015.metaphlan_bugs_list.stool:SID31884 0
## FengQ_2015.metaphlan_bugs_list.stool:SID530050 0
## FengQ_2015.metaphlan_bugs_list.stool:SID530052 0
## FengQ_2015.metaphlan_bugs_list.stool:SID530055 0
## FengQ_2015.metaphlan_bugs_list.stool:SID530074 0
## FengQ_2015.metaphlan_bugs_list.stool:SID530075 0
## FengQ_2015.metaphlan_bugs_list.stool:SID530119 0
## FengQ_2015.metaphlan_bugs_list.stool:SID530154 0
## FengQ_2015.metaphlan_bugs_list.stool:SID530163 0
## FengQ_2015.metaphlan_bugs_list.stool:SID530167 0
## FengQ_2015.metaphlan_bugs_list.stool:SID530177 0
## FengQ_2015.metaphlan_bugs_list.stool:SID530215 0
## FengQ_2015.metaphlan_bugs_list.stool:SID530227 0
## FengQ_2015.metaphlan_bugs_list.stool:SID530251 0
## FengQ_2015.metaphlan_bugs_list.stool:SID530258 0
## FengQ_2015.metaphlan_bugs_list.stool:SID530295 0
## FengQ_2015.metaphlan_bugs_list.stool:SID530315 0
## FengQ_2015.metaphlan_bugs_list.stool:SID530331 0
## FengQ_2015.metaphlan_bugs_list.stool:SID530364 0
## FengQ_2015.metaphlan_bugs_list.stool:SID530368 0
## FengQ_2015.metaphlan_bugs_list.stool:SID530373 0
## FengQ_2015.metaphlan_bugs_list.stool:SID530394 0
## FengQ_2015.metaphlan_bugs_list.stool:SID530444 0
## FengQ_2015.metaphlan_bugs_list.stool:SID530451 0
## FengQ_2015.metaphlan_bugs_list.stool:SID530890 0
## FengQ_2015.metaphlan_bugs_list.stool:SID531128 0
## FengQ_2015.metaphlan_bugs_list.stool:SID531155 0
## FengQ_2015.metaphlan_bugs_list.stool:SID531248 0
## FengQ_2015.metaphlan_bugs_list.stool:SID531274 0
## FengQ_2015.metaphlan_bugs_list.stool:SID531277 0
## FengQ_2015.metaphlan_bugs_list.stool:SID531281 0
## FengQ_2015.metaphlan_bugs_list.stool:SID531333 0
## FengQ_2015.metaphlan_bugs_list.stool:SID531352 0
## FengQ_2015.metaphlan_bugs_list.stool:SID531361 0
## FengQ_2015.metaphlan_bugs_list.stool:SID531382 0
## FengQ_2015.metaphlan_bugs_list.stool:SID531414 0
## FengQ_2015.metaphlan_bugs_list.stool:SID531416 0
## FengQ_2015.metaphlan_bugs_list.stool:SID531424 0
## FengQ_2015.metaphlan_bugs_list.stool:SID531469 0
## FengQ_2015.metaphlan_bugs_list.stool:SID531766 0
## FengQ_2015.metaphlan_bugs_list.stool:SID531775 0
## FengQ_2015.metaphlan_bugs_list.stool:SID532749 0
## FengQ_2015.metaphlan_bugs_list.stool:SID532779 0
## FengQ_2015.metaphlan_bugs_list.stool:SID532796 0
## FengQ_2015.metaphlan_bugs_list.stool:SID532802 0
## FengQ_2015.metaphlan_bugs_list.stool:SID532826 0
## FengQ_2015.metaphlan_bugs_list.stool:SID532915 0
## HanniganGD_2017.metaphlan_bugs_list.stool:MG100180 1
## HanniganGD_2017.metaphlan_bugs_list.stool:MG100179 1
## HanniganGD_2017.metaphlan_bugs_list.stool:MG100178 1
## HanniganGD_2017.metaphlan_bugs_list.stool:MG100177 1
## HanniganGD_2017.metaphlan_bugs_list.stool:MG100176 1
## HanniganGD_2017.metaphlan_bugs_list.stool:MG100175 1
## HanniganGD_2017.metaphlan_bugs_list.stool:MG100174 1
## HanniganGD_2017.metaphlan_bugs_list.stool:MG100173 1
## HanniganGD_2017.metaphlan_bugs_list.stool:MG100172 1
## HanniganGD_2017.metaphlan_bugs_list.stool:MG100171 1
## HanniganGD_2017.metaphlan_bugs_list.stool:MG100170 1
## HanniganGD_2017.metaphlan_bugs_list.stool:MG100169 1
## HanniganGD_2017.metaphlan_bugs_list.stool:MG100168 1
## HanniganGD_2017.metaphlan_bugs_list.stool:MG100167 1
## HanniganGD_2017.metaphlan_bugs_list.stool:MG100166 1
## HanniganGD_2017.metaphlan_bugs_list.stool:MG100165 1
## HanniganGD_2017.metaphlan_bugs_list.stool:MG100164 1
## HanniganGD_2017.metaphlan_bugs_list.stool:MG100163 1
## HanniganGD_2017.metaphlan_bugs_list.stool:MG100162 1
## HanniganGD_2017.metaphlan_bugs_list.stool:MG100161 1
## HanniganGD_2017.metaphlan_bugs_list.stool:MG100160 1
## HanniganGD_2017.metaphlan_bugs_list.stool:MG100159 1
## HanniganGD_2017.metaphlan_bugs_list.stool:MG100158 1
## HanniganGD_2017.metaphlan_bugs_list.stool:MG100157 1
## HanniganGD_2017.metaphlan_bugs_list.stool:MG100156 1
## HanniganGD_2017.metaphlan_bugs_list.stool:MG100155 1
## HanniganGD_2017.metaphlan_bugs_list.stool:MG100154 1
## HanniganGD_2017.metaphlan_bugs_list.stool:MG100153 1
## HanniganGD_2017.metaphlan_bugs_list.stool:MG100152 1
## HanniganGD_2017.metaphlan_bugs_list.stool:MG100151 1
## HanniganGD_2017.metaphlan_bugs_list.stool:MG100150 1
## HanniganGD_2017.metaphlan_bugs_list.stool:MG100149 1
## HanniganGD_2017.metaphlan_bugs_list.stool:MG100148 1
## HanniganGD_2017.metaphlan_bugs_list.stool:MG100147 1
## HanniganGD_2017.metaphlan_bugs_list.stool:MG100146 1
## HanniganGD_2017.metaphlan_bugs_list.stool:MG100145 1
## HanniganGD_2017.metaphlan_bugs_list.stool:MG100144 1
## HanniganGD_2017.metaphlan_bugs_list.stool:MG100143 1
## HanniganGD_2017.metaphlan_bugs_list.stool:MG100142 1
## HanniganGD_2017.metaphlan_bugs_list.stool:MG100141 1
## HanniganGD_2017.metaphlan_bugs_list.stool:MG100140 1
## HanniganGD_2017.metaphlan_bugs_list.stool:MG100139 1
## HanniganGD_2017.metaphlan_bugs_list.stool:MG100138 1
## HanniganGD_2017.metaphlan_bugs_list.stool:MG100137 1
## HanniganGD_2017.metaphlan_bugs_list.stool:MG100136 1
## HanniganGD_2017.metaphlan_bugs_list.stool:MG100134 1
## HanniganGD_2017.metaphlan_bugs_list.stool:MG100133 1
## HanniganGD_2017.metaphlan_bugs_list.stool:MG100132 1
## HanniganGD_2017.metaphlan_bugs_list.stool:MG100131 1
## HanniganGD_2017.metaphlan_bugs_list.stool:MG100130 1
## HanniganGD_2017.metaphlan_bugs_list.stool:MG100129 1
## HanniganGD_2017.metaphlan_bugs_list.stool:MG100128 1
## HanniganGD_2017.metaphlan_bugs_list.stool:MG100127 1
## HanniganGD_2017.metaphlan_bugs_list.stool:MG100126 1
## HanniganGD_2017.metaphlan_bugs_list.stool:MG100125 1
## VogtmannE_2016.metaphlan_bugs_list.stool:MMRS11288076ST-27-0-0 0
## VogtmannE_2016.metaphlan_bugs_list.stool:MMRS11932626ST-27-0-0 0
## VogtmannE_2016.metaphlan_bugs_list.stool:MMRS12272136ST-27-0-0 0
## VogtmannE_2016.metaphlan_bugs_list.stool:MMRS14379078ST-27-0-0 0
## VogtmannE_2016.metaphlan_bugs_list.stool:MMRS14602194ST-27-0-0 0
## VogtmannE_2016.metaphlan_bugs_list.stool:MMRS15137911ST-27-0-0 0
## VogtmannE_2016.metaphlan_bugs_list.stool:MMRS16644320ST-27-0-0 0
## VogtmannE_2016.metaphlan_bugs_list.stool:MMRS17603756ST-27-0-0 0
## VogtmannE_2016.metaphlan_bugs_list.stool:MMRS17963147ST-27-0-0 0
## VogtmannE_2016.metaphlan_bugs_list.stool:MMRS18295921ST-27-0-0 0
## VogtmannE_2016.metaphlan_bugs_list.stool:MMRS20257302ST-27-0-0 0
## VogtmannE_2016.metaphlan_bugs_list.stool:MMRS21365932ST-27-0-0 0
## VogtmannE_2016.metaphlan_bugs_list.stool:MMRS24340226ST-27-0-0 0
## VogtmannE_2016.metaphlan_bugs_list.stool:MMRS25211151ST-27-0-0 0
## VogtmannE_2016.metaphlan_bugs_list.stool:MMRS25641480ST-27-0-0 0
## VogtmannE_2016.metaphlan_bugs_list.stool:MMRS29805707ST-27-0-0 0
## VogtmannE_2016.metaphlan_bugs_list.stool:MMRS31306426ST-27-0-0 0
## VogtmannE_2016.metaphlan_bugs_list.stool:MMRS32573774ST-27-0-0 0
## VogtmannE_2016.metaphlan_bugs_list.stool:MMRS33294861ST-27-0-0 0
## VogtmannE_2016.metaphlan_bugs_list.stool:MMRS34525504ST-27-0-0 0
## VogtmannE_2016.metaphlan_bugs_list.stool:MMRS34569532ST-27-0-0 0
## VogtmannE_2016.metaphlan_bugs_list.stool:MMRS35808664ST-27-0-0 0
## VogtmannE_2016.metaphlan_bugs_list.stool:MMRS36405092ST-27-0-0 0
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## ZellerG_2014.metaphlan_bugs_list.stool:CCIS46047672ST-4-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS46467422ST-4-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS47284573ST-4-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS48174381ST-4-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS48725289ST-4-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS50003399ST-4-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS50148151ST-4-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS50471204ST-4-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS51595129ST-4-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS52370277ST-4-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS53043478ST-4-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS53355328ST-4-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS55230578ST-4-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS58234805ST-4-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS59132091ST-4-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS61287323ST-4-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS62605362ST-3-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS62794166ST-4-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS63448910ST-4-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS63468405ST-4-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS63910149ST-4-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS64773582ST-4-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS64785924ST-20-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS65479369ST-4-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS71301801ST-4-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS71578391ST-4-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS72607085ST-4-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS74239020ST-4-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS76845094ST-20-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS77252613ST-4-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS78100604ST-4-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS78318719ST-4-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS79210440ST-3-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS80834637ST-4-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS81139242ST-4-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS81887263ST-4-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS82146115ST-4-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS82507866ST-3-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS82944710ST-20-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS83870198ST-4-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS84543192ST-4-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS85214191ST-3-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS87116798ST-4-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS87167916ST-4-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS87252800ST-4-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS87605453ST-4-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS88007743ST-4-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS88317640ST-4-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS90164298ST-4-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS91228662ST-4-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS93040568ST-20-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS94417875ST-3-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS94603952ST-4-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS95097901ST-4-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS95409808ST-4-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS98482370ST-3-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS98512455ST-4-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS98832363ST-4-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCMD11006829ST-21-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCMD12232071ST-21-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCMD13071240ST-21-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCMD13934959ST-21-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCMD14479708ST-21-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCMD18872694ST-21-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCMD19497912ST-21-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCMD23101338ST-21-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCMD25511638ST-21-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCMD25963797ST-21-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCMD26709089ST-21-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCMD26925580ST-21-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCMD34381688ST-21-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCMD35802077ST-21-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCMD40701343ST-21-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCMD42428553ST-21-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCMD45988061ST-21-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCMD46222674ST-21-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCMD46947453ST-21-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCMD48236717ST-21-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCMD50071957ST-21-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCMD51864103ST-21-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCMD60079086ST-21-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCMD63399960ST-21-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCMD64503764ST-21-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCMD64776337ST-21-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCMD72895164ST-21-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCMD74930188ST-21-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCMD79987997ST-21-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCMD82866709ST-21-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCMD86114146ST-21-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCMD86707194ST-21-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCMD87156761ST-21-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCMD88272491ST-21-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCMD90311071ST-21-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCMD93344354ST-21-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCMD95433940ST-21-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCMD96553385ST-21-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:MMPU29365221ST -1
## ZellerG_2014.metaphlan_bugs_list.stool:MMPU68403337ST -1
## ZellerG_2014.metaphlan_bugs_list.stool:MMPU72854103ST -1
## ZellerG_2014.metaphlan_bugs_list.stool:MMPU84450604ST -1
## ZellerG_2014.metaphlan_bugs_list.stool:MMPU99077057ST -1
## studyID3
## FengQ_2015.metaphlan_bugs_list.stool:SID31004 0
## FengQ_2015.metaphlan_bugs_list.stool:SID31009 0
## FengQ_2015.metaphlan_bugs_list.stool:SID31021 0
## FengQ_2015.metaphlan_bugs_list.stool:SID31071 0
## FengQ_2015.metaphlan_bugs_list.stool:SID31112 0
## FengQ_2015.metaphlan_bugs_list.stool:SID31129 0
## FengQ_2015.metaphlan_bugs_list.stool:SID31159 0
## FengQ_2015.metaphlan_bugs_list.stool:SID31160 0
## FengQ_2015.metaphlan_bugs_list.stool:SID31188 0
## FengQ_2015.metaphlan_bugs_list.stool:SID31219 0
## FengQ_2015.metaphlan_bugs_list.stool:SID31223 0
## FengQ_2015.metaphlan_bugs_list.stool:SID31236 0
## FengQ_2015.metaphlan_bugs_list.stool:SID31237 0
## FengQ_2015.metaphlan_bugs_list.stool:SID31267 0
## FengQ_2015.metaphlan_bugs_list.stool:SID31276 0
## FengQ_2015.metaphlan_bugs_list.stool:SID31285 0
## FengQ_2015.metaphlan_bugs_list.stool:SID31300 0
## FengQ_2015.metaphlan_bugs_list.stool:SID31328 0
## FengQ_2015.metaphlan_bugs_list.stool:SID31333 0
## FengQ_2015.metaphlan_bugs_list.stool:SID31343 0
## FengQ_2015.metaphlan_bugs_list.stool:SID31360 0
## FengQ_2015.metaphlan_bugs_list.stool:SID31367 0
## FengQ_2015.metaphlan_bugs_list.stool:SID31379 0
## FengQ_2015.metaphlan_bugs_list.stool:SID31416 0
## FengQ_2015.metaphlan_bugs_list.stool:SID31428 0
## FengQ_2015.metaphlan_bugs_list.stool:SID31446 0
## FengQ_2015.metaphlan_bugs_list.stool:SID31450 0
## FengQ_2015.metaphlan_bugs_list.stool:SID31452 0
## FengQ_2015.metaphlan_bugs_list.stool:SID31489 0
## FengQ_2015.metaphlan_bugs_list.stool:SID31493 0
## FengQ_2015.metaphlan_bugs_list.stool:SID31512 0
## FengQ_2015.metaphlan_bugs_list.stool:SID31519 0
## FengQ_2015.metaphlan_bugs_list.stool:SID31537 0
## FengQ_2015.metaphlan_bugs_list.stool:SID31549 0
## FengQ_2015.metaphlan_bugs_list.stool:SID31557 0
## FengQ_2015.metaphlan_bugs_list.stool:SID31637 0
## FengQ_2015.metaphlan_bugs_list.stool:SID31685 0
## FengQ_2015.metaphlan_bugs_list.stool:SID31700 0
## FengQ_2015.metaphlan_bugs_list.stool:SID31711 0
## FengQ_2015.metaphlan_bugs_list.stool:SID31714 0
## FengQ_2015.metaphlan_bugs_list.stool:SID31723 0
## FengQ_2015.metaphlan_bugs_list.stool:SID31749 0
## FengQ_2015.metaphlan_bugs_list.stool:SID31750 0
## FengQ_2015.metaphlan_bugs_list.stool:SID31766 0
## FengQ_2015.metaphlan_bugs_list.stool:SID31865 0
## FengQ_2015.metaphlan_bugs_list.stool:SID31866 0
## FengQ_2015.metaphlan_bugs_list.stool:SID31868 0
## FengQ_2015.metaphlan_bugs_list.stool:SID31870 0
## FengQ_2015.metaphlan_bugs_list.stool:SID31871 0
## FengQ_2015.metaphlan_bugs_list.stool:SID31872 0
## FengQ_2015.metaphlan_bugs_list.stool:SID31873 0
## FengQ_2015.metaphlan_bugs_list.stool:SID31874 0
## FengQ_2015.metaphlan_bugs_list.stool:SID31875 0
## FengQ_2015.metaphlan_bugs_list.stool:SID31876 0
## FengQ_2015.metaphlan_bugs_list.stool:SID31877 0
## FengQ_2015.metaphlan_bugs_list.stool:SID31878 0
## FengQ_2015.metaphlan_bugs_list.stool:SID31879 0
## FengQ_2015.metaphlan_bugs_list.stool:SID31880 0
## FengQ_2015.metaphlan_bugs_list.stool:SID31881 0
## FengQ_2015.metaphlan_bugs_list.stool:SID31883 0
## FengQ_2015.metaphlan_bugs_list.stool:SID31884 0
## FengQ_2015.metaphlan_bugs_list.stool:SID530050 0
## FengQ_2015.metaphlan_bugs_list.stool:SID530052 0
## FengQ_2015.metaphlan_bugs_list.stool:SID530055 0
## FengQ_2015.metaphlan_bugs_list.stool:SID530074 0
## FengQ_2015.metaphlan_bugs_list.stool:SID530075 0
## FengQ_2015.metaphlan_bugs_list.stool:SID530119 0
## FengQ_2015.metaphlan_bugs_list.stool:SID530154 0
## FengQ_2015.metaphlan_bugs_list.stool:SID530163 0
## FengQ_2015.metaphlan_bugs_list.stool:SID530167 0
## FengQ_2015.metaphlan_bugs_list.stool:SID530177 0
## FengQ_2015.metaphlan_bugs_list.stool:SID530215 0
## FengQ_2015.metaphlan_bugs_list.stool:SID530227 0
## FengQ_2015.metaphlan_bugs_list.stool:SID530251 0
## FengQ_2015.metaphlan_bugs_list.stool:SID530258 0
## FengQ_2015.metaphlan_bugs_list.stool:SID530295 0
## FengQ_2015.metaphlan_bugs_list.stool:SID530315 0
## FengQ_2015.metaphlan_bugs_list.stool:SID530331 0
## FengQ_2015.metaphlan_bugs_list.stool:SID530364 0
## FengQ_2015.metaphlan_bugs_list.stool:SID530368 0
## FengQ_2015.metaphlan_bugs_list.stool:SID530373 0
## FengQ_2015.metaphlan_bugs_list.stool:SID530394 0
## FengQ_2015.metaphlan_bugs_list.stool:SID530444 0
## FengQ_2015.metaphlan_bugs_list.stool:SID530451 0
## FengQ_2015.metaphlan_bugs_list.stool:SID530890 0
## FengQ_2015.metaphlan_bugs_list.stool:SID531128 0
## FengQ_2015.metaphlan_bugs_list.stool:SID531155 0
## FengQ_2015.metaphlan_bugs_list.stool:SID531248 0
## FengQ_2015.metaphlan_bugs_list.stool:SID531274 0
## FengQ_2015.metaphlan_bugs_list.stool:SID531277 0
## FengQ_2015.metaphlan_bugs_list.stool:SID531281 0
## FengQ_2015.metaphlan_bugs_list.stool:SID531333 0
## FengQ_2015.metaphlan_bugs_list.stool:SID531352 0
## FengQ_2015.metaphlan_bugs_list.stool:SID531361 0
## FengQ_2015.metaphlan_bugs_list.stool:SID531382 0
## FengQ_2015.metaphlan_bugs_list.stool:SID531414 0
## FengQ_2015.metaphlan_bugs_list.stool:SID531416 0
## FengQ_2015.metaphlan_bugs_list.stool:SID531424 0
## FengQ_2015.metaphlan_bugs_list.stool:SID531469 0
## FengQ_2015.metaphlan_bugs_list.stool:SID531766 0
## FengQ_2015.metaphlan_bugs_list.stool:SID531775 0
## FengQ_2015.metaphlan_bugs_list.stool:SID532749 0
## FengQ_2015.metaphlan_bugs_list.stool:SID532779 0
## FengQ_2015.metaphlan_bugs_list.stool:SID532796 0
## FengQ_2015.metaphlan_bugs_list.stool:SID532802 0
## FengQ_2015.metaphlan_bugs_list.stool:SID532826 0
## FengQ_2015.metaphlan_bugs_list.stool:SID532915 0
## HanniganGD_2017.metaphlan_bugs_list.stool:MG100180 0
## HanniganGD_2017.metaphlan_bugs_list.stool:MG100179 0
## HanniganGD_2017.metaphlan_bugs_list.stool:MG100178 0
## HanniganGD_2017.metaphlan_bugs_list.stool:MG100177 0
## HanniganGD_2017.metaphlan_bugs_list.stool:MG100176 0
## HanniganGD_2017.metaphlan_bugs_list.stool:MG100175 0
## HanniganGD_2017.metaphlan_bugs_list.stool:MG100174 0
## HanniganGD_2017.metaphlan_bugs_list.stool:MG100173 0
## HanniganGD_2017.metaphlan_bugs_list.stool:MG100172 0
## HanniganGD_2017.metaphlan_bugs_list.stool:MG100171 0
## HanniganGD_2017.metaphlan_bugs_list.stool:MG100170 0
## HanniganGD_2017.metaphlan_bugs_list.stool:MG100169 0
## HanniganGD_2017.metaphlan_bugs_list.stool:MG100168 0
## HanniganGD_2017.metaphlan_bugs_list.stool:MG100167 0
## HanniganGD_2017.metaphlan_bugs_list.stool:MG100166 0
## HanniganGD_2017.metaphlan_bugs_list.stool:MG100165 0
## HanniganGD_2017.metaphlan_bugs_list.stool:MG100164 0
## HanniganGD_2017.metaphlan_bugs_list.stool:MG100163 0
## HanniganGD_2017.metaphlan_bugs_list.stool:MG100162 0
## HanniganGD_2017.metaphlan_bugs_list.stool:MG100161 0
## HanniganGD_2017.metaphlan_bugs_list.stool:MG100160 0
## HanniganGD_2017.metaphlan_bugs_list.stool:MG100159 0
## HanniganGD_2017.metaphlan_bugs_list.stool:MG100158 0
## HanniganGD_2017.metaphlan_bugs_list.stool:MG100157 0
## HanniganGD_2017.metaphlan_bugs_list.stool:MG100156 0
## HanniganGD_2017.metaphlan_bugs_list.stool:MG100155 0
## HanniganGD_2017.metaphlan_bugs_list.stool:MG100154 0
## HanniganGD_2017.metaphlan_bugs_list.stool:MG100153 0
## HanniganGD_2017.metaphlan_bugs_list.stool:MG100152 0
## HanniganGD_2017.metaphlan_bugs_list.stool:MG100151 0
## HanniganGD_2017.metaphlan_bugs_list.stool:MG100150 0
## HanniganGD_2017.metaphlan_bugs_list.stool:MG100149 0
## HanniganGD_2017.metaphlan_bugs_list.stool:MG100148 0
## HanniganGD_2017.metaphlan_bugs_list.stool:MG100147 0
## HanniganGD_2017.metaphlan_bugs_list.stool:MG100146 0
## HanniganGD_2017.metaphlan_bugs_list.stool:MG100145 0
## HanniganGD_2017.metaphlan_bugs_list.stool:MG100144 0
## HanniganGD_2017.metaphlan_bugs_list.stool:MG100143 0
## HanniganGD_2017.metaphlan_bugs_list.stool:MG100142 0
## HanniganGD_2017.metaphlan_bugs_list.stool:MG100141 0
## HanniganGD_2017.metaphlan_bugs_list.stool:MG100140 0
## HanniganGD_2017.metaphlan_bugs_list.stool:MG100139 0
## HanniganGD_2017.metaphlan_bugs_list.stool:MG100138 0
## HanniganGD_2017.metaphlan_bugs_list.stool:MG100137 0
## HanniganGD_2017.metaphlan_bugs_list.stool:MG100136 0
## HanniganGD_2017.metaphlan_bugs_list.stool:MG100134 0
## HanniganGD_2017.metaphlan_bugs_list.stool:MG100133 0
## HanniganGD_2017.metaphlan_bugs_list.stool:MG100132 0
## HanniganGD_2017.metaphlan_bugs_list.stool:MG100131 0
## HanniganGD_2017.metaphlan_bugs_list.stool:MG100130 0
## HanniganGD_2017.metaphlan_bugs_list.stool:MG100129 0
## HanniganGD_2017.metaphlan_bugs_list.stool:MG100128 0
## HanniganGD_2017.metaphlan_bugs_list.stool:MG100127 0
## HanniganGD_2017.metaphlan_bugs_list.stool:MG100126 0
## HanniganGD_2017.metaphlan_bugs_list.stool:MG100125 0
## VogtmannE_2016.metaphlan_bugs_list.stool:MMRS11288076ST-27-0-0 1
## VogtmannE_2016.metaphlan_bugs_list.stool:MMRS11932626ST-27-0-0 1
## VogtmannE_2016.metaphlan_bugs_list.stool:MMRS12272136ST-27-0-0 1
## VogtmannE_2016.metaphlan_bugs_list.stool:MMRS14379078ST-27-0-0 1
## VogtmannE_2016.metaphlan_bugs_list.stool:MMRS14602194ST-27-0-0 1
## VogtmannE_2016.metaphlan_bugs_list.stool:MMRS15137911ST-27-0-0 1
## VogtmannE_2016.metaphlan_bugs_list.stool:MMRS16644320ST-27-0-0 1
## VogtmannE_2016.metaphlan_bugs_list.stool:MMRS17603756ST-27-0-0 1
## VogtmannE_2016.metaphlan_bugs_list.stool:MMRS17963147ST-27-0-0 1
## VogtmannE_2016.metaphlan_bugs_list.stool:MMRS18295921ST-27-0-0 1
## VogtmannE_2016.metaphlan_bugs_list.stool:MMRS20257302ST-27-0-0 1
## VogtmannE_2016.metaphlan_bugs_list.stool:MMRS21365932ST-27-0-0 1
## VogtmannE_2016.metaphlan_bugs_list.stool:MMRS24340226ST-27-0-0 1
## VogtmannE_2016.metaphlan_bugs_list.stool:MMRS25211151ST-27-0-0 1
## VogtmannE_2016.metaphlan_bugs_list.stool:MMRS25641480ST-27-0-0 1
## VogtmannE_2016.metaphlan_bugs_list.stool:MMRS29805707ST-27-0-0 1
## VogtmannE_2016.metaphlan_bugs_list.stool:MMRS31306426ST-27-0-0 1
## VogtmannE_2016.metaphlan_bugs_list.stool:MMRS32573774ST-27-0-0 1
## VogtmannE_2016.metaphlan_bugs_list.stool:MMRS33294861ST-27-0-0 1
## VogtmannE_2016.metaphlan_bugs_list.stool:MMRS34525504ST-27-0-0 1
## VogtmannE_2016.metaphlan_bugs_list.stool:MMRS34569532ST-27-0-0 1
## VogtmannE_2016.metaphlan_bugs_list.stool:MMRS35808664ST-27-0-0 1
## VogtmannE_2016.metaphlan_bugs_list.stool:MMRS36405092ST-27-0-0 1
## VogtmannE_2016.metaphlan_bugs_list.stool:MMRS38861560ST-27-0-0 1
## VogtmannE_2016.metaphlan_bugs_list.stool:MMRS38954404ST-27-0-0 1
## VogtmannE_2016.metaphlan_bugs_list.stool:MMRS39415781ST-27-0-0 1
## VogtmannE_2016.metaphlan_bugs_list.stool:MMRS39582183ST-27-0-0 1
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## ZellerG_2014.metaphlan_bugs_list.stool:CCIS48725289ST-4-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS50003399ST-4-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS50148151ST-4-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS50471204ST-4-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS51595129ST-4-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS52370277ST-4-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS53043478ST-4-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS53355328ST-4-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS55230578ST-4-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS58234805ST-4-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS59132091ST-4-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS61287323ST-4-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS62605362ST-3-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS62794166ST-4-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS63448910ST-4-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS63468405ST-4-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS63910149ST-4-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS64773582ST-4-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS64785924ST-20-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS65479369ST-4-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS71301801ST-4-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS71578391ST-4-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS72607085ST-4-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS74239020ST-4-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS76845094ST-20-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS77252613ST-4-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS78100604ST-4-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS78318719ST-4-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS79210440ST-3-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS80834637ST-4-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS81139242ST-4-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS81887263ST-4-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS82146115ST-4-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS82507866ST-3-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS82944710ST-20-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS83870198ST-4-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS84543192ST-4-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS85214191ST-3-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS87116798ST-4-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS87167916ST-4-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS87252800ST-4-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS87605453ST-4-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS88007743ST-4-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS88317640ST-4-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS90164298ST-4-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS91228662ST-4-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS93040568ST-20-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS94417875ST-3-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS94603952ST-4-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS95097901ST-4-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS95409808ST-4-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS98482370ST-3-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS98512455ST-4-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS98832363ST-4-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCMD11006829ST-21-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCMD12232071ST-21-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCMD13071240ST-21-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCMD13934959ST-21-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCMD14479708ST-21-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCMD18872694ST-21-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCMD19497912ST-21-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCMD23101338ST-21-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCMD25511638ST-21-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCMD25963797ST-21-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCMD26709089ST-21-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCMD26925580ST-21-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCMD34381688ST-21-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCMD35802077ST-21-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCMD40701343ST-21-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCMD42428553ST-21-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCMD45988061ST-21-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCMD46222674ST-21-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCMD46947453ST-21-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCMD48236717ST-21-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCMD50071957ST-21-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCMD51864103ST-21-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCMD60079086ST-21-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCMD63399960ST-21-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCMD64503764ST-21-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCMD64776337ST-21-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCMD72895164ST-21-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCMD74930188ST-21-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCMD79987997ST-21-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCMD82866709ST-21-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCMD86114146ST-21-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCMD86707194ST-21-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCMD87156761ST-21-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCMD88272491ST-21-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCMD90311071ST-21-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCMD93344354ST-21-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCMD95433940ST-21-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCMD96553385ST-21-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:MMPU29365221ST -1
## ZellerG_2014.metaphlan_bugs_list.stool:MMPU68403337ST -1
## ZellerG_2014.metaphlan_bugs_list.stool:MMPU72854103ST -1
## ZellerG_2014.metaphlan_bugs_list.stool:MMPU84450604ST -1
## ZellerG_2014.metaphlan_bugs_list.stool:MMPU99077057ST -1
## studyID4
## FengQ_2015.metaphlan_bugs_list.stool:SID31004 0
## FengQ_2015.metaphlan_bugs_list.stool:SID31009 0
## FengQ_2015.metaphlan_bugs_list.stool:SID31021 0
## FengQ_2015.metaphlan_bugs_list.stool:SID31071 0
## FengQ_2015.metaphlan_bugs_list.stool:SID31112 0
## FengQ_2015.metaphlan_bugs_list.stool:SID31129 0
## FengQ_2015.metaphlan_bugs_list.stool:SID31159 0
## FengQ_2015.metaphlan_bugs_list.stool:SID31160 0
## FengQ_2015.metaphlan_bugs_list.stool:SID31188 0
## FengQ_2015.metaphlan_bugs_list.stool:SID31219 0
## FengQ_2015.metaphlan_bugs_list.stool:SID31223 0
## FengQ_2015.metaphlan_bugs_list.stool:SID31236 0
## FengQ_2015.metaphlan_bugs_list.stool:SID31237 0
## FengQ_2015.metaphlan_bugs_list.stool:SID31267 0
## FengQ_2015.metaphlan_bugs_list.stool:SID31276 0
## FengQ_2015.metaphlan_bugs_list.stool:SID31285 0
## FengQ_2015.metaphlan_bugs_list.stool:SID31300 0
## FengQ_2015.metaphlan_bugs_list.stool:SID31328 0
## FengQ_2015.metaphlan_bugs_list.stool:SID31333 0
## FengQ_2015.metaphlan_bugs_list.stool:SID31343 0
## FengQ_2015.metaphlan_bugs_list.stool:SID31360 0
## FengQ_2015.metaphlan_bugs_list.stool:SID31367 0
## FengQ_2015.metaphlan_bugs_list.stool:SID31379 0
## FengQ_2015.metaphlan_bugs_list.stool:SID31416 0
## FengQ_2015.metaphlan_bugs_list.stool:SID31428 0
## FengQ_2015.metaphlan_bugs_list.stool:SID31446 0
## FengQ_2015.metaphlan_bugs_list.stool:SID31450 0
## FengQ_2015.metaphlan_bugs_list.stool:SID31452 0
## FengQ_2015.metaphlan_bugs_list.stool:SID31489 0
## FengQ_2015.metaphlan_bugs_list.stool:SID31493 0
## FengQ_2015.metaphlan_bugs_list.stool:SID31512 0
## FengQ_2015.metaphlan_bugs_list.stool:SID31519 0
## FengQ_2015.metaphlan_bugs_list.stool:SID31537 0
## FengQ_2015.metaphlan_bugs_list.stool:SID31549 0
## FengQ_2015.metaphlan_bugs_list.stool:SID31557 0
## FengQ_2015.metaphlan_bugs_list.stool:SID31637 0
## FengQ_2015.metaphlan_bugs_list.stool:SID31685 0
## FengQ_2015.metaphlan_bugs_list.stool:SID31700 0
## FengQ_2015.metaphlan_bugs_list.stool:SID31711 0
## FengQ_2015.metaphlan_bugs_list.stool:SID31714 0
## FengQ_2015.metaphlan_bugs_list.stool:SID31723 0
## FengQ_2015.metaphlan_bugs_list.stool:SID31749 0
## FengQ_2015.metaphlan_bugs_list.stool:SID31750 0
## FengQ_2015.metaphlan_bugs_list.stool:SID31766 0
## FengQ_2015.metaphlan_bugs_list.stool:SID31865 0
## FengQ_2015.metaphlan_bugs_list.stool:SID31866 0
## FengQ_2015.metaphlan_bugs_list.stool:SID31868 0
## FengQ_2015.metaphlan_bugs_list.stool:SID31870 0
## FengQ_2015.metaphlan_bugs_list.stool:SID31871 0
## FengQ_2015.metaphlan_bugs_list.stool:SID31872 0
## FengQ_2015.metaphlan_bugs_list.stool:SID31873 0
## FengQ_2015.metaphlan_bugs_list.stool:SID31874 0
## FengQ_2015.metaphlan_bugs_list.stool:SID31875 0
## FengQ_2015.metaphlan_bugs_list.stool:SID31876 0
## FengQ_2015.metaphlan_bugs_list.stool:SID31877 0
## FengQ_2015.metaphlan_bugs_list.stool:SID31878 0
## FengQ_2015.metaphlan_bugs_list.stool:SID31879 0
## FengQ_2015.metaphlan_bugs_list.stool:SID31880 0
## FengQ_2015.metaphlan_bugs_list.stool:SID31881 0
## FengQ_2015.metaphlan_bugs_list.stool:SID31883 0
## FengQ_2015.metaphlan_bugs_list.stool:SID31884 0
## FengQ_2015.metaphlan_bugs_list.stool:SID530050 0
## FengQ_2015.metaphlan_bugs_list.stool:SID530052 0
## FengQ_2015.metaphlan_bugs_list.stool:SID530055 0
## FengQ_2015.metaphlan_bugs_list.stool:SID530074 0
## FengQ_2015.metaphlan_bugs_list.stool:SID530075 0
## FengQ_2015.metaphlan_bugs_list.stool:SID530119 0
## FengQ_2015.metaphlan_bugs_list.stool:SID530154 0
## FengQ_2015.metaphlan_bugs_list.stool:SID530163 0
## FengQ_2015.metaphlan_bugs_list.stool:SID530167 0
## FengQ_2015.metaphlan_bugs_list.stool:SID530177 0
## FengQ_2015.metaphlan_bugs_list.stool:SID530215 0
## FengQ_2015.metaphlan_bugs_list.stool:SID530227 0
## FengQ_2015.metaphlan_bugs_list.stool:SID530251 0
## FengQ_2015.metaphlan_bugs_list.stool:SID530258 0
## FengQ_2015.metaphlan_bugs_list.stool:SID530295 0
## FengQ_2015.metaphlan_bugs_list.stool:SID530315 0
## FengQ_2015.metaphlan_bugs_list.stool:SID530331 0
## FengQ_2015.metaphlan_bugs_list.stool:SID530364 0
## FengQ_2015.metaphlan_bugs_list.stool:SID530368 0
## FengQ_2015.metaphlan_bugs_list.stool:SID530373 0
## FengQ_2015.metaphlan_bugs_list.stool:SID530394 0
## FengQ_2015.metaphlan_bugs_list.stool:SID530444 0
## FengQ_2015.metaphlan_bugs_list.stool:SID530451 0
## FengQ_2015.metaphlan_bugs_list.stool:SID530890 0
## FengQ_2015.metaphlan_bugs_list.stool:SID531128 0
## FengQ_2015.metaphlan_bugs_list.stool:SID531155 0
## FengQ_2015.metaphlan_bugs_list.stool:SID531248 0
## FengQ_2015.metaphlan_bugs_list.stool:SID531274 0
## FengQ_2015.metaphlan_bugs_list.stool:SID531277 0
## FengQ_2015.metaphlan_bugs_list.stool:SID531281 0
## FengQ_2015.metaphlan_bugs_list.stool:SID531333 0
## FengQ_2015.metaphlan_bugs_list.stool:SID531352 0
## FengQ_2015.metaphlan_bugs_list.stool:SID531361 0
## FengQ_2015.metaphlan_bugs_list.stool:SID531382 0
## FengQ_2015.metaphlan_bugs_list.stool:SID531414 0
## FengQ_2015.metaphlan_bugs_list.stool:SID531416 0
## FengQ_2015.metaphlan_bugs_list.stool:SID531424 0
## FengQ_2015.metaphlan_bugs_list.stool:SID531469 0
## FengQ_2015.metaphlan_bugs_list.stool:SID531766 0
## FengQ_2015.metaphlan_bugs_list.stool:SID531775 0
## FengQ_2015.metaphlan_bugs_list.stool:SID532749 0
## FengQ_2015.metaphlan_bugs_list.stool:SID532779 0
## FengQ_2015.metaphlan_bugs_list.stool:SID532796 0
## FengQ_2015.metaphlan_bugs_list.stool:SID532802 0
## FengQ_2015.metaphlan_bugs_list.stool:SID532826 0
## FengQ_2015.metaphlan_bugs_list.stool:SID532915 0
## HanniganGD_2017.metaphlan_bugs_list.stool:MG100180 0
## HanniganGD_2017.metaphlan_bugs_list.stool:MG100179 0
## HanniganGD_2017.metaphlan_bugs_list.stool:MG100178 0
## HanniganGD_2017.metaphlan_bugs_list.stool:MG100177 0
## HanniganGD_2017.metaphlan_bugs_list.stool:MG100176 0
## HanniganGD_2017.metaphlan_bugs_list.stool:MG100175 0
## HanniganGD_2017.metaphlan_bugs_list.stool:MG100174 0
## HanniganGD_2017.metaphlan_bugs_list.stool:MG100173 0
## HanniganGD_2017.metaphlan_bugs_list.stool:MG100172 0
## HanniganGD_2017.metaphlan_bugs_list.stool:MG100171 0
## HanniganGD_2017.metaphlan_bugs_list.stool:MG100170 0
## HanniganGD_2017.metaphlan_bugs_list.stool:MG100169 0
## HanniganGD_2017.metaphlan_bugs_list.stool:MG100168 0
## HanniganGD_2017.metaphlan_bugs_list.stool:MG100167 0
## HanniganGD_2017.metaphlan_bugs_list.stool:MG100166 0
## HanniganGD_2017.metaphlan_bugs_list.stool:MG100165 0
## HanniganGD_2017.metaphlan_bugs_list.stool:MG100164 0
## HanniganGD_2017.metaphlan_bugs_list.stool:MG100163 0
## HanniganGD_2017.metaphlan_bugs_list.stool:MG100162 0
## HanniganGD_2017.metaphlan_bugs_list.stool:MG100161 0
## HanniganGD_2017.metaphlan_bugs_list.stool:MG100160 0
## HanniganGD_2017.metaphlan_bugs_list.stool:MG100159 0
## HanniganGD_2017.metaphlan_bugs_list.stool:MG100158 0
## HanniganGD_2017.metaphlan_bugs_list.stool:MG100157 0
## HanniganGD_2017.metaphlan_bugs_list.stool:MG100156 0
## HanniganGD_2017.metaphlan_bugs_list.stool:MG100155 0
## HanniganGD_2017.metaphlan_bugs_list.stool:MG100154 0
## HanniganGD_2017.metaphlan_bugs_list.stool:MG100153 0
## HanniganGD_2017.metaphlan_bugs_list.stool:MG100152 0
## HanniganGD_2017.metaphlan_bugs_list.stool:MG100151 0
## HanniganGD_2017.metaphlan_bugs_list.stool:MG100150 0
## HanniganGD_2017.metaphlan_bugs_list.stool:MG100149 0
## HanniganGD_2017.metaphlan_bugs_list.stool:MG100148 0
## HanniganGD_2017.metaphlan_bugs_list.stool:MG100147 0
## HanniganGD_2017.metaphlan_bugs_list.stool:MG100146 0
## HanniganGD_2017.metaphlan_bugs_list.stool:MG100145 0
## HanniganGD_2017.metaphlan_bugs_list.stool:MG100144 0
## HanniganGD_2017.metaphlan_bugs_list.stool:MG100143 0
## HanniganGD_2017.metaphlan_bugs_list.stool:MG100142 0
## HanniganGD_2017.metaphlan_bugs_list.stool:MG100141 0
## HanniganGD_2017.metaphlan_bugs_list.stool:MG100140 0
## HanniganGD_2017.metaphlan_bugs_list.stool:MG100139 0
## HanniganGD_2017.metaphlan_bugs_list.stool:MG100138 0
## HanniganGD_2017.metaphlan_bugs_list.stool:MG100137 0
## HanniganGD_2017.metaphlan_bugs_list.stool:MG100136 0
## HanniganGD_2017.metaphlan_bugs_list.stool:MG100134 0
## HanniganGD_2017.metaphlan_bugs_list.stool:MG100133 0
## HanniganGD_2017.metaphlan_bugs_list.stool:MG100132 0
## HanniganGD_2017.metaphlan_bugs_list.stool:MG100131 0
## HanniganGD_2017.metaphlan_bugs_list.stool:MG100130 0
## HanniganGD_2017.metaphlan_bugs_list.stool:MG100129 0
## HanniganGD_2017.metaphlan_bugs_list.stool:MG100128 0
## HanniganGD_2017.metaphlan_bugs_list.stool:MG100127 0
## HanniganGD_2017.metaphlan_bugs_list.stool:MG100126 0
## HanniganGD_2017.metaphlan_bugs_list.stool:MG100125 0
## VogtmannE_2016.metaphlan_bugs_list.stool:MMRS11288076ST-27-0-0 0
## VogtmannE_2016.metaphlan_bugs_list.stool:MMRS11932626ST-27-0-0 0
## VogtmannE_2016.metaphlan_bugs_list.stool:MMRS12272136ST-27-0-0 0
## VogtmannE_2016.metaphlan_bugs_list.stool:MMRS14379078ST-27-0-0 0
## VogtmannE_2016.metaphlan_bugs_list.stool:MMRS14602194ST-27-0-0 0
## VogtmannE_2016.metaphlan_bugs_list.stool:MMRS15137911ST-27-0-0 0
## VogtmannE_2016.metaphlan_bugs_list.stool:MMRS16644320ST-27-0-0 0
## VogtmannE_2016.metaphlan_bugs_list.stool:MMRS17603756ST-27-0-0 0
## VogtmannE_2016.metaphlan_bugs_list.stool:MMRS17963147ST-27-0-0 0
## VogtmannE_2016.metaphlan_bugs_list.stool:MMRS18295921ST-27-0-0 0
## VogtmannE_2016.metaphlan_bugs_list.stool:MMRS20257302ST-27-0-0 0
## VogtmannE_2016.metaphlan_bugs_list.stool:MMRS21365932ST-27-0-0 0
## VogtmannE_2016.metaphlan_bugs_list.stool:MMRS24340226ST-27-0-0 0
## VogtmannE_2016.metaphlan_bugs_list.stool:MMRS25211151ST-27-0-0 0
## VogtmannE_2016.metaphlan_bugs_list.stool:MMRS25641480ST-27-0-0 0
## VogtmannE_2016.metaphlan_bugs_list.stool:MMRS29805707ST-27-0-0 0
## VogtmannE_2016.metaphlan_bugs_list.stool:MMRS31306426ST-27-0-0 0
## VogtmannE_2016.metaphlan_bugs_list.stool:MMRS32573774ST-27-0-0 0
## VogtmannE_2016.metaphlan_bugs_list.stool:MMRS33294861ST-27-0-0 0
## VogtmannE_2016.metaphlan_bugs_list.stool:MMRS34525504ST-27-0-0 0
## VogtmannE_2016.metaphlan_bugs_list.stool:MMRS34569532ST-27-0-0 0
## VogtmannE_2016.metaphlan_bugs_list.stool:MMRS35808664ST-27-0-0 0
## VogtmannE_2016.metaphlan_bugs_list.stool:MMRS36405092ST-27-0-0 0
## VogtmannE_2016.metaphlan_bugs_list.stool:MMRS38861560ST-27-0-0 0
## VogtmannE_2016.metaphlan_bugs_list.stool:MMRS38954404ST-27-0-0 0
## VogtmannE_2016.metaphlan_bugs_list.stool:MMRS39415781ST-27-0-0 0
## VogtmannE_2016.metaphlan_bugs_list.stool:MMRS39582183ST-27-0-0 0
## VogtmannE_2016.metaphlan_bugs_list.stool:MMRS40913371ST-27-0-0 0
## VogtmannE_2016.metaphlan_bugs_list.stool:MMRS41266697ST-27-0-0 0
## VogtmannE_2016.metaphlan_bugs_list.stool:MMRS41711735ST-27-0-0 0
## VogtmannE_2016.metaphlan_bugs_list.stool:MMRS42780924ST-27-0-0 0
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## ZellerG_2014.metaphlan_bugs_list.stool:CCIS51595129ST-4-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS52370277ST-4-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS53043478ST-4-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS53355328ST-4-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS55230578ST-4-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS58234805ST-4-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS59132091ST-4-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS61287323ST-4-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS62605362ST-3-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS62794166ST-4-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS63448910ST-4-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS63468405ST-4-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS63910149ST-4-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS64773582ST-4-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS64785924ST-20-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS65479369ST-4-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS71301801ST-4-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS71578391ST-4-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS72607085ST-4-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS74239020ST-4-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS76845094ST-20-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS77252613ST-4-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS78100604ST-4-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS78318719ST-4-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS79210440ST-3-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS80834637ST-4-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS81139242ST-4-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS81887263ST-4-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS82146115ST-4-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS82507866ST-3-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS82944710ST-20-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS83870198ST-4-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS84543192ST-4-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS85214191ST-3-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS87116798ST-4-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS87167916ST-4-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS87252800ST-4-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS87605453ST-4-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS88007743ST-4-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS88317640ST-4-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS90164298ST-4-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS91228662ST-4-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS93040568ST-20-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS94417875ST-3-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS94603952ST-4-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS95097901ST-4-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS95409808ST-4-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS98482370ST-3-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS98512455ST-4-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS98832363ST-4-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCMD11006829ST-21-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCMD12232071ST-21-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCMD13071240ST-21-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCMD13934959ST-21-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCMD14479708ST-21-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCMD18872694ST-21-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCMD19497912ST-21-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCMD23101338ST-21-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCMD25511638ST-21-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCMD25963797ST-21-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCMD26709089ST-21-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCMD26925580ST-21-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCMD34381688ST-21-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCMD35802077ST-21-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCMD40701343ST-21-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCMD42428553ST-21-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCMD45988061ST-21-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCMD46222674ST-21-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCMD46947453ST-21-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCMD48236717ST-21-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCMD50071957ST-21-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCMD51864103ST-21-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCMD60079086ST-21-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCMD63399960ST-21-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCMD64503764ST-21-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCMD64776337ST-21-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCMD72895164ST-21-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCMD74930188ST-21-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCMD79987997ST-21-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCMD82866709ST-21-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCMD86114146ST-21-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCMD86707194ST-21-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCMD87156761ST-21-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCMD88272491ST-21-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCMD90311071ST-21-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCMD93344354ST-21-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCMD95433940ST-21-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCMD96553385ST-21-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:MMPU29365221ST -1
## ZellerG_2014.metaphlan_bugs_list.stool:MMPU68403337ST -1
## ZellerG_2014.metaphlan_bugs_list.stool:MMPU72854103ST -1
## ZellerG_2014.metaphlan_bugs_list.stool:MMPU84450604ST -1
## ZellerG_2014.metaphlan_bugs_list.stool:MMPU99077057ST -1
##
## $terms
## D_before ~ studyID
## attr(,"variables")
## list(D_before, studyID)
## attr(,"factors")
## studyID
## D_before 0
## studyID 1
## attr(,"term.labels")
## [1] "studyID"
## attr(,"order")
## [1] 1
## attr(,"intercept")
## [1] 1
## attr(,"response")
## [1] 1
## attr(,".Environment")
## <environment: R_GlobalEnv>
##
## attr(,"class")
## [1] "adonis"print(fit_adonis_after)## $aov.tab
## Permutation: free
## Number of permutations: 999
##
## Terms added sequentially (first to last)
##
## Df SumsOfSqs MeanSqs F.Model R2 Pr(>F)
## studyID 4 4.939 1.23463 4.2855 0.03044 0.001 ***
## Residuals 546 157.298 0.28809 0.96956
## Total 550 162.237 1.00000
## ---
## Signif. codes: 0 '***' 0.001 '**' 0.01 '*' 0.05 '.' 0.1 ' ' 1
##
## $call
## adonis(formula = D_after ~ studyID, data = CRC_meta)
##
## $coefficients
## NULL
##
## $coef.sites
## [,1] [,2] [,3] [,4] [,5]
## (Intercept) 0.766306741 0.725972558 0.6553869713 0.701152902 0.855197416
## studyID1 -0.004778105 -0.014914188 -0.0154706122 -0.001350895 -0.020739721
## studyID2 0.019172586 0.030715730 0.0194404686 -0.035973899 0.002316480
## studyID3 -0.013817328 -0.009583381 -0.0008041124 0.014116700 0.015084037
## studyID4 0.009180497 0.015231254 0.0169841871 0.026385939 0.004899186
## [,6] [,7] [,8] [,9] [,10]
## (Intercept) 0.79637929 0.810815309 0.721628167 0.776211687 0.714909841
## studyID1 -0.02199869 -0.028859125 -0.003520624 0.001530621 -0.015875512
## studyID2 -0.01560336 0.018657514 -0.031429117 0.018699239 0.017492362
## studyID3 0.01969857 0.009336095 0.010813214 -0.024804425 0.003763544
## studyID4 0.02004709 0.004342621 0.022004519 0.018994657 0.012266642
## [,11] [,12] [,13] [,14] [,15]
## (Intercept) 0.7716549847 0.716144758 0.79489896 0.694546591 0.697050234
## studyID1 0.0002602168 -0.013482288 -0.02110577 -0.020430285 -0.017107952
## studyID2 0.0143112225 0.031132760 -0.01059509 0.012316024 0.033406058
## studyID3 -0.0110793003 0.003742574 0.02010939 0.004937778 -0.005354227
## studyID4 0.0105257056 -0.011294680 0.01392556 0.007374745 0.002676213
## [,16] [,17] [,18] [,19] [,20]
## (Intercept) 0.726750402 0.783434755 0.681097505 0.712608354 0.8679849127
## studyID1 -0.006810981 -0.006777773 -0.003001983 -0.025626862 -0.0142331029
## studyID2 0.036783357 0.030866022 0.028124354 0.019782776 0.0242927053
## studyID3 -0.024821783 -0.016187941 -0.010112533 0.012229595 -0.0009747805
## studyID4 0.012799067 0.008624695 0.013225225 0.005840785 0.0002753738
## [,21] [,22] [,23] [,24] [,25]
## (Intercept) 0.7110275077 0.842484557 0.722973193 0.85647089 0.766586639
## studyID1 -0.0213107610 -0.017051533 -0.014308109 -0.01524759 -0.015115607
## studyID2 0.0323670282 0.023792520 0.002101727 -0.03508201 -0.004494754
## studyID3 -0.0008818054 -0.002745771 0.012422998 0.02028854 0.012398209
## studyID4 0.0124206672 -0.005482626 0.013010499 0.02397725 0.011592092
## [,26] [,27] [,28] [,29] [,30]
## (Intercept) 0.804880544 0.853597307 0.70373408 0.725300362 0.795376782
## studyID1 -0.005226894 -0.001394162 -0.01689284 -0.026468859 -0.018188192
## studyID2 0.029714791 0.030961271 0.05344996 0.032990199 -0.007259567
## studyID3 -0.010815636 -0.013931183 -0.01681745 0.003027269 0.010531707
## studyID4 -0.004340533 -0.009501378 0.00509250 0.006757251 0.008651971
## [,31] [,32] [,33] [,34] [,35]
## (Intercept) 0.691710170 0.675136183 0.753944731 0.69442970 0.853404490
## studyID1 -0.020855122 0.002738455 -0.025415661 -0.01195430 -0.024446450
## studyID2 -0.005082949 -0.010445738 0.014905727 -0.01550963 -0.006090725
## studyID3 0.019589863 0.000253895 0.004488438 0.01791992 0.023382840
## studyID4 0.015191125 0.020580481 0.011677544 0.02561037 0.011165485
## [,36] [,37] [,38] [,39] [,40]
## (Intercept) 0.788454394 0.773536211 0.69212867 0.92089250 0.827824514
## studyID1 -0.027111227 -0.014037276 -0.01303853 -0.01482009 -0.038722148
## studyID2 0.005492286 0.033299485 -0.00662288 -0.01868803 0.002971906
## studyID3 0.024198290 -0.009770946 0.00667118 0.01454012 0.024031650
## studyID4 0.005348114 0.002142897 0.01815445 0.01392717 0.013124070
## [,41] [,42] [,43] [,44] [,45]
## (Intercept) 0.863338886 0.694992707 0.721425798 0.68291229 0.771954133
## studyID1 -0.013103875 -0.002279417 -0.013600936 -0.01239604 -0.017718761
## studyID2 0.007406864 -0.033587203 0.030856760 -0.01741159 0.001572297
## studyID3 0.001646414 0.018581277 -0.009508332 0.01406526 0.013317751
## studyID4 0.007413549 0.023475221 0.012798587 0.01895188 0.004854962
## [,46] [,47] [,48] [,49] [,50]
## (Intercept) 0.773171567 0.750814665 0.843933361 0.720901593 0.73987611
## studyID1 -0.002079860 0.001282913 -0.027975346 -0.026618883 -0.01891801
## studyID2 0.012013594 0.065344236 0.003689557 0.012546900 0.04018383
## studyID3 -0.005786951 -0.042706036 0.017979653 0.011523084 -0.01580283
## studyID4 0.010853699 -0.010989156 0.010617152 0.008707032 0.01358949
## [,51] [,52] [,53] [,54] [,55]
## (Intercept) 0.727115560 0.773828435 0.709926455 0.762018627 0.7549207296
## studyID1 -0.013978636 -0.001450019 -0.004415048 -0.006339957 0.0083125023
## studyID2 0.020403267 0.055427730 0.016101596 0.055205338 0.0395225400
## studyID3 -0.004183109 -0.023958498 -0.001763599 -0.016165492 -0.0292676304
## studyID4 0.009466742 -0.006526532 0.013948029 -0.005858623 -0.0001208118
## [,56] [,57] [,58] [,59] [,60]
## (Intercept) 0.711928785 0.780217389 0.801309393 0.726602172 0.811709007
## studyID1 0.001917916 -0.025057302 -0.005181483 -0.005681833 0.004603483
## studyID2 0.041887447 0.022762794 0.065415884 0.027410257 0.067348269
## studyID3 -0.021646988 0.006026261 -0.025902157 -0.004982610 -0.043497119
## studyID4 0.006520592 0.003131535 -0.006677037 0.005213634 -0.014399534
## [,61] [,62] [,63] [,64] [,65]
## (Intercept) 0.73585229 0.729775621 0.78931158 0.67841401 0.85461512
## studyID1 -0.01561683 -0.007503357 -0.04022294 -0.01063251 -0.02178037
## studyID2 0.03445972 0.049405169 0.01261778 0.01542174 -0.01200343
## studyID3 -0.01212518 -0.025443696 0.01633095 0.01048973 0.01535326
## studyID4 0.01425002 0.009530368 0.01815929 0.01147426 0.01908482
## [,66] [,67] [,68] [,69] [,70]
## (Intercept) 0.736042524 0.752043184 0.895102336 0.807290008 0.704183687
## studyID1 -0.016046165 -0.024104934 -0.013955111 -0.024247842 0.001041467
## studyID2 0.032634614 0.019224898 -0.004528273 -0.005431478 0.006438266
## studyID3 -0.008773731 0.003037857 0.009807002 0.014106030 -0.010299337
## studyID4 0.002272261 0.017682876 0.011832080 0.019957946 0.014602139
## [,71] [,72] [,73] [,74] [,75]
## (Intercept) 0.771929877 0.716536260 0.8159274150 0.85591517 0.668358726
## studyID1 -0.020291558 -0.023649874 0.0006850392 -0.01342874 -0.020876627
## studyID2 0.013104996 0.008463703 -0.0286393158 -0.02322365 0.019352142
## studyID3 0.004685777 0.011566127 0.0106418516 0.02276250 0.002820955
## studyID4 0.009997890 0.015457476 0.0165306287 0.01621871 0.011824335
## [,76] [,77] [,78] [,79] [,80]
## (Intercept) 0.744816093 0.72220264 0.703493041 0.692817741 0.739623537
## studyID1 -0.004713292 -0.01597629 -0.010366243 -0.018601428 -0.015532046
## studyID2 0.020162344 -0.02499811 0.043653982 0.029784553 -0.016084041
## studyID3 -0.010039189 0.02054582 -0.015917229 -0.000281383 0.007873535
## studyID4 0.009267980 0.02038490 0.005161017 0.014268438 0.028598061
## [,81] [,82] [,83] [,84] [,85]
## (Intercept) 0.79065335 0.740043398 0.76160072 0.776454281 0.700313765
## studyID1 -0.01136637 -0.001241696 -0.02187304 -0.007250690 -0.008897860
## studyID2 0.03173290 0.039847971 -0.02539669 0.012815918 0.049303775
## studyID3 -0.01462647 -0.014322155 0.02680978 -0.005385830 -0.026145875
## studyID4 0.00700442 0.003404404 0.01937793 0.009515594 0.006442293
## [,86] [,87] [,88] [,89] [,90]
## (Intercept) 0.732335612 0.670520737 0.846286868 0.9422388346 0.731929471
## studyID1 0.001782569 -0.007299491 0.001068219 -0.0138249648 -0.001116667
## studyID2 0.035693411 -0.001305291 0.058096685 0.0161976685 0.038523884
## studyID3 -0.022639174 0.004757349 -0.043897090 0.0002073339 -0.012572266
## studyID4 0.005540496 0.018467148 -0.007910978 -0.0083213579 0.001402960
## [,91] [,92] [,93] [,94] [,95]
## (Intercept) 0.7671954288 0.7482905388 0.768213656 0.879769850 0.793017451
## studyID1 -0.0149756479 0.0008352898 -0.010283525 0.004245903 0.007834337
## studyID2 0.0201115938 -0.0206758900 0.045189010 0.040541031 0.035664290
## studyID3 0.0006794482 0.0111095665 -0.023849898 -0.034186847 -0.023104792
## studyID4 0.0049856889 0.0168301168 0.007814366 -0.015691817 -0.002089961
## [,96] [,97] [,98] [,99] [,100]
## (Intercept) 0.7386335540 0.704662855 9.227124e-01 0.740059580 0.857996418
## studyID1 0.0007446446 -0.013072055 -9.577118e-05 0.002197264 0.007112508
## studyID2 0.0243622228 0.058517521 2.897159e-02 0.033237843 0.051730253
## studyID3 -0.0138110422 -0.016971781 -8.285548e-04 -0.020069770 -0.024895258
## studyID4 0.0041398517 0.002190065 -2.613702e-02 0.003696876 -0.014866868
## [,101] [,102] [,103] [,104] [,105]
## (Intercept) 0.779781353 0.788473251 0.760443349 0.723718426 0.698666035
## studyID1 -0.001421368 -0.014974640 0.002977787 -0.003542523 -0.007366792
## studyID2 0.017750414 0.037426052 0.020113283 0.044461952 0.025076545
## studyID3 -0.007370304 -0.013852149 -0.019088664 -0.029553809 -0.003800282
## studyID4 0.004614304 0.009159005 0.014839862 0.011376084 0.006282752
## [,106] [,107] [,108] [,109] [,110]
## (Intercept) 0.787639680 0.7376132923 0.682943842 0.7303660100 0.713690437
## studyID1 -0.018815124 -0.0003623417 -0.007067881 0.0071436100 -0.002635118
## studyID2 0.011443776 0.0344046036 -0.033819421 -0.0347840830 -0.032698901
## studyID3 0.009087636 -0.0107897671 0.016101710 0.0002027338 0.010941441
## studyID4 0.009261928 0.0053200762 0.025386875 0.0290924309 0.029520875
## [,111] [,112] [,113] [,114] [,115]
## (Intercept) 0.758381501 0.715517135 0.780361512 0.813206273 0.7676857255
## studyID1 0.005293155 0.004118919 0.003993119 0.008096708 0.0007493501
## studyID2 -0.066834373 -0.022432163 -0.083079751 -0.033811932 -0.0661415209
## studyID3 0.029589250 0.013190015 0.035912096 0.013415213 0.0254307464
## studyID4 0.028171942 0.012752683 0.029368316 0.011654062 0.0293065049
## [,116] [,117] [,118] [,119] [,120]
## (Intercept) 0.744885355 0.8361974223 0.69897247 7.201777e-01 0.8852416858
## studyID1 0.006248013 0.0009822862 0.02299191 9.999321e-05 -0.0180098868
## studyID2 -0.078424524 0.0120521680 -0.06094402 -7.550142e-03 0.0043078201
## studyID3 0.026398461 -0.0188053967 0.01309417 5.888762e-03 0.0111506214
## studyID4 0.034387878 0.0140385296 0.02276518 1.722354e-02 0.0008755473
## [,121] [,122] [,123] [,124] [,125]
## (Intercept) 0.67763365 0.69910351 0.80693932 0.828731680 0.808551281
## studyID1 0.01492834 0.01175889 0.00980958 0.004577212 0.003702595
## studyID2 -0.05128644 -0.05494442 0.02222895 -0.031689798 -0.039646420
## studyID3 0.01503466 0.01141919 -0.01610050 0.014158710 0.017004863
## studyID4 0.02496145 0.03155367 -0.00283067 0.009979954 0.016302903
## [,126] [,127] [,128] [,129] [,130]
## (Intercept) 0.7755735584 0.724406331 0.74533970 0.8063342265 0.808769213
## studyID1 -0.0002116601 0.009163618 0.01322625 0.0005854209 -0.002499344
## studyID2 -0.0502546068 -0.049127905 -0.04369777 -0.0511296442 0.004005667
## studyID3 0.0190322826 0.013935295 0.01292359 0.0204434487 -0.002560618
## studyID4 0.0304112513 0.019690883 0.01722468 0.0243012167 0.006033938
## [,131] [,132] [,133] [,134] [,135]
## (Intercept) 0.7500153285 0.734415057 0.798665511 0.84214528 0.755677522
## studyID1 0.0007743526 0.002501616 -0.005333795 0.01661546 0.017815069
## studyID2 -0.0294012541 -0.063675110 -0.061166653 -0.05571469 -0.053131406
## studyID3 0.0150014921 0.019985053 0.027630316 0.01071908 0.004737657
## studyID4 0.0171108485 0.032124911 0.029582959 0.01842126 0.030357397
## [,136] [,137] [,138] [,139] [,140]
## (Intercept) 0.758343094 0.824467198 0.79531892 0.7643093267 0.914691411
## studyID1 0.007882728 -0.006114233 0.01366908 0.0004384146 0.001825251
## studyID2 -0.059575520 -0.018342782 -0.04628724 -0.0572903826 -0.015671091
## studyID3 0.023088930 0.023136231 0.01386684 0.0254967328 0.006727092
## studyID4 0.028032915 0.008528636 0.01499618 0.0280061900 0.006498796
## [,141] [,142] [,143] [,144] [,145]
## (Intercept) 0.838100156 0.72410873 0.824565549 0.738897889 0.747935232
## studyID1 -0.002281009 -0.00324575 -0.001131273 0.010813388 0.003207330
## studyID2 -0.032215383 -0.03975800 -0.020011899 -0.032571480 0.002226776
## studyID3 0.019394712 0.02706376 0.007228761 0.016708657 -0.001323991
## studyID4 0.007711987 0.02286743 0.013494418 0.008771235 0.004807145
## [,146] [,147] [,148] [,149] [,150]
## (Intercept) 0.994288453 0.702836884 0.75420060 0.76348499 0.798782945
## studyID1 0.003398746 0.005003098 0.01685360 0.00194191 0.007238525
## studyID2 -0.013647995 -0.039150163 -0.04687627 -0.06548508 -0.052990800
## studyID3 0.003360126 0.013671840 0.01706422 0.03180163 0.014053805
## studyID4 0.003143913 0.020938537 0.01286606 0.02433855 0.026152655
## [,151] [,152] [,153] [,154] [,155]
## (Intercept) 0.786771694 0.77859335 0.808903982 0.711791467 0.8558093767
## studyID1 0.008169594 0.00242505 0.013407092 0.000347561 0.0055624057
## studyID2 -0.051806067 -0.07272665 -0.036596583 -0.015555126 0.0077725596
## studyID3 0.018796191 0.02948932 0.004799171 0.008484113 -0.0040588521
## studyID4 0.012232604 0.03221942 0.016011839 0.016403711 -0.0007743116
## [,156] [,157] [,158] [,159] [,160]
## (Intercept) 0.77816344 0.724204592 0.81136122 0.780590279 0.736164668
## studyID1 -0.01050558 0.018958276 0.01597054 0.006342226 -0.004665312
## studyID2 -0.04079594 -0.051917763 -0.05588766 -0.028692420 -0.070277575
## studyID3 0.03529719 0.009690005 0.01505626 0.009845492 0.030971142
## studyID4 0.01750125 0.026396362 0.01831559 0.014983154 0.033627973
## [,161] [,162] [,163] [,164] [,165]
## (Intercept) 0.80549648 0.71402126 0.738616261 0.666472926 0.688918555
## studyID1 0.01095437 -0.00465242 -0.004146159 -0.004371457 0.008970974
## studyID2 -0.05782953 -0.02961077 0.054070233 0.028476068 0.042083106
## studyID3 0.01653814 0.01461139 -0.024207213 -0.021862756 -0.031296313
## studyID4 0.02598000 0.02122283 -0.006964469 0.016763513 0.005496887
## [,166] [,167] [,168] [,169] [,170]
## (Intercept) 0.735411750 0.668179321 0.780628751 0.670452580 0.807532264
## studyID1 -0.008923913 0.002164942 -0.008353960 -0.007603875 0.001502945
## studyID2 0.039152773 0.036779413 0.030761582 0.048889350 0.061025390
## studyID3 -0.010607721 -0.026846281 -0.014780767 -0.021888988 -0.045869148
## studyID4 -0.001921972 0.008617047 0.003563203 0.006606413 0.005131744
## [,171] [,172] [,173] [,174] [,175]
## (Intercept) 0.734974341 0.741736370 0.728862666 0.756396548 0.78122137
## studyID1 0.001340766 0.006603294 0.004689816 0.013244992 0.01711885
## studyID2 0.067620094 0.062867126 0.020588418 -0.003823503 -0.02167292
## studyID3 -0.042275551 -0.049196935 -0.026568080 -0.011684137 -0.00304423
## studyID4 -0.004077595 -0.004656875 0.016872185 0.014029820 0.01049679
## [,176] [,177] [,178] [,179] [,180]
## (Intercept) 0.763629996 0.679247273 0.718012314 0.806067937 0.7949768035
## studyID1 0.001737160 -0.002229719 -0.002836639 0.015190467 0.0001268195
## studyID2 0.038070112 0.010941359 0.048585348 0.037874704 0.0435981491
## studyID3 -0.026984610 -0.012047270 -0.023187918 -0.036820885 -0.0378004775
## studyID4 0.006742118 0.021510124 -0.003084822 -0.002259541 0.0116120709
## [,181] [,182] [,183] [,184] [,185]
## (Intercept) 0.714179073 0.813126324 0.723763762 0.837724012 0.760795746
## studyID1 0.002873935 -0.003457316 0.004695654 0.004036557 -0.010372877
## studyID2 0.028097714 0.064090322 0.035304612 0.049277204 0.021303637
## studyID3 -0.013103268 -0.044962318 -0.034292658 -0.037802448 -0.008044717
## studyID4 0.008581382 -0.010985817 0.022925515 -0.011826398 0.009405508
## [,186] [,187] [,188] [,189] [,190]
## (Intercept) 0.744487070 0.74342604 0.749731403 0.732818881 0.754345133
## studyID1 0.005124707 0.01203315 -0.001675843 0.011333258 -0.002790804
## studyID2 0.036604210 0.02034932 0.012147245 0.049353627 0.018680159
## studyID3 -0.030678379 -0.03565293 -0.010600207 -0.047502297 -0.016256385
## studyID4 0.010539318 0.02700296 0.012118402 0.008119833 0.017049297
## [,191] [,192] [,193] [,194] [,195]
## (Intercept) 0.7642799209 0.863413707 0.786434638 0.7426788312 0.6804401936
## studyID1 0.0003953426 -0.005595050 0.002606733 -0.0006237633 0.0065216939
## studyID2 0.0413592576 0.024335050 0.035584339 0.0685495003 -0.0002700093
## studyID3 -0.0274356467 -0.013808356 -0.035187547 -0.0515589309 -0.0024711924
## studyID4 -0.0005258116 -0.001677403 0.008275862 -0.0041244974 0.0082552807
## [,196] [,197] [,198] [,199] [,200]
## (Intercept) 0.800549265 0.851309176 0.768115294 0.728427604 0.858885134
## studyID1 0.011771258 0.003433094 0.011694428 -0.005907450 -0.008280836
## studyID2 0.012357141 0.037810683 0.039421179 0.055860920 0.050467348
## studyID3 -0.022821575 -0.019832688 -0.034595086 -0.031731332 -0.023031744
## studyID4 0.008077325 -0.010249686 -0.005185492 -0.001431876 -0.010811041
## [,201] [,202] [,203] [,204] [,205]
## (Intercept) 0.757016304 0.746073522 0.9559329856 0.730677909 0.791843626
## studyID1 0.013343370 0.002800703 -0.0096467631 0.008288591 0.007018565
## studyID2 -0.032537587 0.045584464 0.0101105479 0.031537790 0.045082365
## studyID3 0.004130729 -0.035789524 -0.0008873957 -0.031776604 -0.043041440
## studyID4 0.019054540 0.011331613 -0.0076692826 0.013840524 -0.002968828
## [,206] [,207] [,208] [,209] [,210]
## (Intercept) 0.731210306 0.713750806 0.7220186066 0.7488870710 0.7771148231
## studyID1 0.004962930 -0.006894579 0.0001402128 -0.0001449559 0.0006075793
## studyID2 0.054836094 0.061965597 0.0303633593 0.0463611314 0.0521050418
## studyID3 -0.039952838 -0.024557789 -0.0187637447 -0.0303813273 -0.0411693222
## studyID4 -0.005543378 -0.003299027 -0.0003365246 0.0053235090 -0.0029651624
## [,211] [,212] [,213] [,214] [,215]
## (Intercept) 0.792312539 0.761896973 0.840941428 0.723174606 0.7254518480
## studyID1 0.003234437 0.009043851 0.010422857 0.005054599 0.0130656453
## studyID2 0.029646735 0.052185017 -0.014400422 0.044502365 0.0437450439
## studyID3 -0.009116436 -0.039281839 -0.004018601 -0.036979412 -0.0399404405
## studyID4 -0.003983216 -0.001567457 0.003607654 0.004608233 0.0002900174
## [,216] [,217] [,218] [,219] [,220]
## (Intercept) 0.894689255 0.803792436 0.737342767 0.787119677 0.7175273054
## studyID1 0.003984116 0.005563013 -0.001045054 0.011711204 0.0088926219
## studyID2 0.032838873 0.049441768 0.031840645 0.052232018 0.0469088315
## studyID3 -0.022002584 -0.043943667 -0.014873410 -0.050547169 -0.0269825831
## studyID4 -0.007563427 -0.008513753 0.002251695 0.001709915 0.0006972873
## [,221] [,222] [,223] [,224] [,225]
## (Intercept) 0.901238221 0.77425195 0.783773139 0.762514405 0.724976288
## studyID1 -0.006925351 0.01408715 -0.028483998 -0.001215444 0.007948087
## studyID2 0.010588313 -0.02196341 0.039783618 0.050742791 0.045559156
## studyID3 -0.007489933 -0.01038596 -0.005435562 -0.027086991 -0.035790539
## studyID4 0.005053079 0.02015709 0.005765353 -0.004511505 -0.002585337
## [,226] [,227] [,228] [,229] [,230]
## (Intercept) 0.8273480290 0.72349034 0.739364360 0.813237761 0.711013618
## studyID1 0.0124261773 0.00320207 0.005368668 0.002959034 -0.009948743
## studyID2 0.0423472145 0.02991037 0.031569525 0.022312618 0.006110439
## studyID3 -0.0380371527 -0.03163227 -0.031941750 -0.018413556 -0.002754660
## studyID4 -0.0002116539 0.01663878 0.001564281 0.002994751 0.019749445
## [,231] [,232] [,233] [,234] [,235]
## (Intercept) 0.704870016 0.689581915 0.748414313 0.711652300 0.783327543
## studyID1 0.011334719 -0.014049370 0.009088178 0.016289580 0.008218608
## studyID2 -0.001695763 0.035444182 0.020850191 0.014491521 0.031190583
## studyID3 -0.013851259 -0.008601640 -0.030402808 -0.036072950 -0.030087859
## studyID4 0.015633620 0.002110213 0.020917920 0.006736767 0.006149608
## [,236] [,237] [,238] [,239] [,240]
## (Intercept) 0.763051987 0.756896469 0.768112740 0.790767470 0.719923253
## studyID1 -0.004126474 -0.009714082 0.002996569 0.005598566 0.008066520
## studyID2 0.019685750 0.018808405 0.057645511 0.041149289 0.034491150
## studyID3 -0.015375620 -0.005217304 -0.040552321 -0.024297016 -0.039418104
## studyID4 0.013387051 0.010838861 0.002250711 -0.001656532 0.005540441
## [,241] [,242] [,243] [,244] [,245]
## (Intercept) 0.82518361 0.772790447 0.717356479 0.685653282 0.9183170096
## studyID1 -0.01739310 0.004634755 0.012959742 0.002569674 -0.0004746863
## studyID2 0.05165189 0.041599958 0.038220946 0.039837780 0.0092050741
## studyID3 -0.02051808 -0.036069052 -0.032005461 -0.033974764 -0.0051350006
## studyID4 -0.01021133 0.018616116 0.003405517 0.014543660 -0.0037955768
## [,246] [,247] [,248] [,249] [,250]
## (Intercept) 0.711116114 0.801887614 0.735026040 0.671299474 0.711999180
## studyID1 -0.001950222 0.017567731 -0.000542036 -0.010278830 -0.006791868
## studyID2 0.038636521 -0.019738185 0.010054278 0.018804888 0.042657562
## studyID3 -0.026243358 -0.006824538 -0.009954394 -0.006714645 -0.025255424
## studyID4 0.006348402 0.008783416 0.015540824 0.015411071 0.007699368
## [,251] [,252] [,253] [,254] [,255]
## (Intercept) 0.696835171 0.70121082 0.715956891 0.7566854126 0.805588372
## studyID1 -0.020219035 -0.00105412 0.009856556 0.0002025021 0.009386172
## studyID2 0.049807339 0.02997978 -0.017937555 0.0476997900 0.021383721
## studyID3 -0.016205097 -0.01723103 -0.002066020 -0.0295393472 -0.020448409
## studyID4 0.008433351 0.01404448 0.017139439 0.0002552261 0.002210936
## [,256] [,257] [,258] [,259] [,260]
## (Intercept) 0.705163809 0.743302899 0.7354813138 0.700642842 0.694758138
## studyID1 -0.001761049 0.007430998 -0.0006196491 0.002247404 -0.004901101
## studyID2 0.067333883 0.038569604 0.0419218856 0.012368404 0.052158951
## studyID3 -0.039476464 -0.028781544 -0.0296330485 -0.013226123 -0.028628514
## studyID4 -0.001090956 0.008946265 0.0133090943 0.014817870 0.008321282
## [,261] [,262] [,263] [,264] [,265]
## (Intercept) 0.836709623 0.682518753 0.743943988 0.742008119 0.853159683
## studyID1 0.004738918 -0.014552321 -0.004478126 -0.003160510 -0.001799531
## studyID2 0.045731252 0.038262550 0.047686055 0.006031524 -0.003962625
## studyID3 -0.034532271 -0.016320987 -0.023225544 -0.003809719 -0.003561833
## studyID4 -0.004248057 0.004431497 -0.002261800 0.015627485 0.010721242
## [,266] [,267] [,268] [,269] [,270]
## (Intercept) 0.805028460 0.7429535414 0.763624761 0.844422339 0.75962664
## studyID1 -0.000505050 -0.0006754509 0.009714734 -0.020414198 -0.01237455
## studyID2 0.002127474 0.0059297009 0.015011604 0.010472301 0.04169954
## studyID3 -0.003718738 -0.0046411989 -0.006816675 0.015527591 -0.01202683
## studyID4 0.006875369 0.0132714477 -0.009763230 0.004074659 -0.01152764
## [,271] [,272] [,273] [,274] [,275]
## (Intercept) 0.749126210 0.86319145 0.809773275 0.8857581844 0.802555316
## studyID1 -0.009005200 0.00325943 -0.013108413 0.0104236858 0.004617935
## studyID2 0.046094616 0.03088894 0.009307171 0.0054220536 0.056595087
## studyID3 -0.012670451 -0.01655230 0.010394992 0.0008281461 -0.025972851
## studyID4 -0.005126601 -0.00754415 -0.006469796 -0.0127142142 -0.016265239
## [,276] [,277] [,278] [,279] [,280]
## (Intercept) 0.766363292 0.787623749 0.84352852 0.770076517 0.741352524
## studyID1 0.005602577 -0.005174148 0.00722788 -0.005959794 0.013502239
## studyID2 0.032423136 0.035150226 0.04540114 0.046110633 0.010803537
## studyID3 -0.017194136 -0.007882919 -0.02026634 -0.010009533 -0.003356779
## studyID4 -0.007913131 -0.013821872 -0.01985466 -0.014776483 -0.015707413
## [,281] [,282] [,283] [,284] [,285]
## (Intercept) 0.855090740 0.791368080 0.791517616 0.888257698 0.8020239359
## studyID1 0.009749078 -0.022720393 0.003994518 0.003974862 -0.0009677342
## studyID2 0.022694223 0.013728290 0.028435841 0.030192143 0.0408983934
## studyID3 -0.013367248 0.009444629 -0.013755286 -0.009554696 -0.0075954960
## studyID4 -0.012437752 -0.001288177 -0.003105370 -0.018551069 -0.0187342727
## [,286] [,287] [,288] [,289] [,290]
## (Intercept) 0.880292264 0.851806421 0.799115442 0.83904341 0.830664697
## studyID1 0.012368541 -0.004634892 0.009813823 0.01077399 -0.014927127
## studyID2 -0.041380478 0.035694051 0.001225963 0.04239008 0.019093792
## studyID3 0.014454563 0.000368850 -0.012398263 -0.01347916 -0.001248200
## studyID4 0.008660353 -0.021210410 -0.003754601 -0.02450265 -0.004284367
## [,291] [,292] [,293] [,294] [,295]
## (Intercept) 0.7433071542 0.816012749 0.752073100 0.7655260350 0.79079867
## studyID1 0.0001571618 0.010576400 -0.020763581 -0.0118979868 -0.00532380
## studyID2 0.0516521284 0.020047259 0.054685435 0.0308724171 -0.03067971
## studyID3 -0.0103677079 -0.010015291 -0.005610635 0.0003586977 0.02861172
## studyID4 -0.0241234767 -0.007070219 -0.011402865 -0.0054881551 0.01102603
## [,296] [,297] [,298] [,299] [,300]
## (Intercept) 0.826323442 0.732976961 0.7781649006 0.7398552020 0.7106814597
## studyID1 0.007587782 0.002412994 -0.0184113305 -0.0033623590 0.0110675089
## studyID2 0.058591778 -0.009374026 0.0269625345 -0.0111375085 0.0119653844
## studyID3 -0.022447427 0.005587330 0.0061544999 0.0147055072 -0.0008759458
## studyID4 -0.027888591 0.005903901 -0.0001014518 0.0007126487 -0.0019171539
## [,301] [,302] [,303] [,304] [,305]
## (Intercept) 0.83391192 0.755982504 0.731423153 0.789234955 0.695806525
## studyID1 -0.00314012 0.009126075 -0.012569320 0.003536101 0.001091215
## studyID2 0.03428472 0.048640291 0.037266548 0.016777433 0.026490473
## studyID3 -0.00756259 -0.016089374 -0.016840632 -0.006272666 -0.002285420
## studyID4 -0.01409535 -0.025047438 0.004300267 0.003318929 -0.002396478
## [,306] [,307] [,308] [,309] [,310]
## (Intercept) 0.758243514 0.805035397 0.7401743618 0.767174621 0.708367948
## studyID1 -0.002757038 0.007127991 -0.0064796418 0.007787641 -0.012647809
## studyID2 -0.026516423 0.045305696 0.0316130351 0.044895996 0.014807902
## studyID3 0.018829289 -0.032351972 -0.0006905355 -0.007455676 0.004072693
## studyID4 0.013243930 -0.015535846 -0.0179872357 -0.024937226 0.002330505
## [,311] [,312] [,313] [,314] [,315]
## (Intercept) 0.722683836 0.720904505 0.73465583 0.680462219 0.814538316
## studyID1 -0.003860101 -0.010272008 0.01550368 -0.001024733 -0.006515134
## studyID2 -0.043291284 0.048335089 0.05595363 0.004749019 0.015090835
## studyID3 0.025439196 -0.013105769 -0.03407100 0.002233249 -0.005243892
## studyID4 0.021178092 -0.001321225 -0.02165767 0.007339786 0.001124996
## [,316] [,317] [,318] [,319] [,320]
## (Intercept) 0.927951475 0.684443830 0.769872982 0.8719314793 0.76194272
## studyID1 -0.009949083 0.004015083 0.006830668 0.0026954681 0.01397089
## studyID2 0.011661044 0.003888696 0.048434808 0.0072497710 -0.05490922
## studyID3 0.004117249 0.001373888 -0.042354156 -0.0008577008 0.02073243
## studyID4 -0.013345733 0.007764547 -0.008320061 -0.0106633141 0.01369856
## [,321] [,322] [,323] [,324] [,325]
## (Intercept) 0.7301399008 0.710489275 0.831464225 0.72687176 0.888624477
## studyID1 -0.0106433330 0.006620697 0.009508963 -0.01386080 -0.005725428
## studyID2 0.0133697791 0.034937946 0.042652181 0.04925326 0.031768433
## studyID3 0.0008543302 -0.006970991 -0.021352620 -0.01285331 0.001596679
## studyID4 0.0066083510 -0.008532391 -0.018673661 -0.01427643 -0.019747901
## [,326] [,327] [,328] [,329] [,330]
## (Intercept) 0.786685346 0.701691202 0.6907202027 0.762206357 0.697709239
## studyID1 0.006198728 -0.004365745 0.0076541748 -0.007540348 -0.006756548
## studyID2 0.023236197 0.051858468 -0.0058095492 0.033864379 0.030766370
## studyID3 -0.012433735 -0.011907425 0.0083177455 -0.004890899 -0.003251851
## studyID4 -0.006924192 -0.014063522 0.0009102677 -0.008555466 0.002049012
## [,331] [,332] [,333] [,334] [,335]
## (Intercept) 0.77190101 0.756162318 0.755344884 0.739319783 0.749188195
## studyID1 0.01047520 0.001405270 0.001586996 -0.004081408 -0.008979173
## studyID2 0.07157457 -0.010924233 0.040827957 0.018469857 0.017010071
## studyID3 -0.04763331 0.004807428 -0.013392971 0.006886102 0.004625583
## studyID4 -0.01826220 0.010111708 -0.013010898 -0.021341024 -0.002432511
## [,336] [,337] [,338] [,339] [,340]
## (Intercept) 0.7464570709 0.702605985 0.705758642 0.668985385 0.828600789
## studyID1 -0.0302333417 0.011155285 -0.007392467 0.004023128 -0.011313202
## studyID2 0.0526546358 0.033653493 0.038806845 -0.024119464 0.058021005
## studyID3 -0.0006293345 -0.027149704 -0.009472099 0.013308384 -0.007654562
## studyID4 -0.0092651041 0.007999727 -0.015078869 0.019803818 -0.026508297
## [,341] [,342] [,343] [,344] [,345]
## (Intercept) 0.682842707 0.84589306 0.7470797961 0.745058516 0.772068785
## studyID1 0.002903184 0.00814700 0.0006428701 -0.005405295 0.004481457
## studyID2 0.035419886 0.05237105 -0.0059087084 0.035827890 0.004424202
## studyID3 -0.014381037 -0.01822482 0.0046554283 -0.014014009 0.008050029
## studyID4 -0.003540338 -0.03020224 0.0044948419 0.001021928 -0.015250788
## [,346] [,347] [,348] [,349] [,350]
## (Intercept) 0.713850461 0.72171689 0.719496819 0.716878225 0.718279838
## studyID1 0.001976234 0.01218090 -0.007838290 0.004833645 0.015416996
## studyID2 0.003653138 0.04809904 0.048541764 0.047365561 0.026607896
## studyID3 0.004004580 -0.02114509 -0.009908448 -0.026854738 -0.018702446
## studyID4 -0.002661560 -0.01194763 -0.011771386 -0.007750986 -0.001670383
## [,351] [,352] [,353] [,354] [,355]
## (Intercept) 0.752108075 0.7565455290 0.813396501 0.703592815 0.709914936
## studyID1 -0.003065789 0.0034088338 -0.006777974 -0.001519510 0.015653298
## studyID2 0.051908172 0.0267531719 0.037256530 0.054143196 0.022931506
## studyID3 -0.016285429 -0.0009307351 -0.013612508 -0.021017072 -0.027327257
## studyID4 -0.009925802 -0.0131221462 -0.012495644 0.001761687 -0.003848297
## [,356] [,357] [,358] [,359] [,360]
## (Intercept) 0.76987296 0.726650941 0.745758831 0.769160759 0.713258018
## studyID1 0.01027114 -0.005912651 0.008458224 0.004642343 0.009654026
## studyID2 0.04666662 0.025218798 0.040714561 0.012003739 -0.004905556
## studyID3 -0.01426692 -0.004275700 -0.015595247 0.002850507 0.005983902
## studyID4 -0.01375663 0.001099925 -0.008289999 -0.012762364 0.003938447
## [,361] [,362] [,363] [,364] [,365]
## (Intercept) 0.9357374161 0.7701380186 0.7222087452 0.878967867 0.807552343
## studyID1 -0.0038435790 0.0232905778 0.0006673742 0.006699312 -0.003813458
## studyID2 0.0127521041 -0.0301702688 0.0362290846 0.012096802 0.003920343
## studyID3 -0.0003145044 0.0045772472 -0.0206505514 -0.003777319 0.007674338
## studyID4 -0.0153362060 -0.0001469654 -0.0008871570 -0.012140791 -0.002903291
## [,366] [,367] [,368] [,369] [,370]
## (Intercept) 0.746794775 0.794436332 0.701258214 0.83810430 0.7817993293
## studyID1 -0.012852133 0.011475720 -0.003537903 -0.01173527 0.0120568544
## studyID2 0.031839362 0.032751668 0.045265799 -0.01435733 0.0107190867
## studyID3 -0.006001872 -0.025316959 -0.009217546 0.01475220 -0.0115339034
## studyID4 -0.009761192 -0.003518724 -0.011118955 0.01044170 -0.0007708548
## [,371] [,372] [,373] [,374] [,375]
## (Intercept) 0.778490934 0.6974254135 0.800644923 0.826738705 0.8169515048
## studyID1 0.002348056 0.0109173560 -0.003757806 0.008478999 -0.0035588565
## studyID2 0.042851306 0.0146323460 0.035896342 0.036050172 0.0142331490
## studyID3 -0.011256113 -0.0024918050 -0.006973323 -0.007913702 -0.0004951263
## studyID4 -0.016608026 -0.0001542987 -0.007214531 -0.028042931 -0.0060685775
## [,376] [,377] [,378] [,379] [,380]
## (Intercept) 0.716752617 0.760796791 0.7458175177 0.77368891 0.782620389
## studyID1 0.010618098 0.008772308 0.0154499292 0.01190202 -0.011375641
## studyID2 -0.003521172 0.051350258 0.0139094036 0.03488197 0.021909627
## studyID3 -0.001024052 -0.044852094 -0.0278394770 -0.01989141 -0.002524942
## studyID4 0.005046581 -0.007419302 0.0001783223 -0.01005988 -0.004092631
## [,381] [,382] [,383] [,384] [,385]
## (Intercept) 0.845048759 0.736233467 0.82018728 0.835365461 0.7218305037
## studyID1 0.008386392 0.007264714 0.01616416 0.009109035 0.0085480408
## studyID2 0.045896557 0.029245740 0.06067330 0.047032648 0.0223441908
## studyID3 -0.023021261 -0.012729537 -0.03683531 -0.024419537 -0.0003390019
## studyID4 -0.020297553 -0.006827194 -0.01850700 -0.021091827 -0.0132046777
## [,386] [,387] [,388] [,389] [,390]
## (Intercept) 0.860084719 0.701842559 0.785832173 0.75079976 0.718578360
## studyID1 -0.004720308 0.004693090 0.003135467 -0.01567854 0.009003382
## studyID2 0.051396590 0.043497345 0.047158789 -0.01144704 -0.026052008
## studyID3 -0.003620791 -0.009423856 -0.028815589 0.02010472 0.012479812
## studyID4 -0.034326884 -0.009074230 -0.014385657 0.00762238 0.014532203
## [,391] [,392] [,393] [,394] [,395]
## (Intercept) 0.742865664 0.70443996 0.6703525550 0.799353826 7.014241e-01
## studyID1 -0.018685866 0.01033018 -0.0006107572 -0.014117570 3.029259e-03
## studyID2 0.008912321 0.04400981 0.0065225276 0.008858458 -9.037608e-03
## studyID3 0.006760032 -0.02227120 0.0055280618 0.013669692 -5.220202e-05
## studyID4 0.005700374 -0.01656865 0.0114820305 -0.003482781 2.116769e-02
## [,396] [,397] [,398] [,399] [,400]
## (Intercept) 0.807123065 0.683162123 0.726087617 0.690034791 0.6580461807
## studyID1 0.009031211 -0.010659259 0.011100106 -0.010365478 0.0003116769
## studyID2 0.066077139 0.022861659 0.030230302 0.046977796 0.0045514129
## studyID3 -0.047801417 0.003060281 -0.021642417 -0.013046907 -0.0003552827
## studyID4 -0.011166175 0.011390837 0.006670196 0.002930564 0.0210331199
## [,401] [,402] [,403] [,404] [,405]
## (Intercept) 0.784774324 0.696717685 0.8015194293 0.715638518 0.693507656
## studyID1 0.003255248 -0.012004456 -0.0082739242 -0.004702677 0.003901433
## studyID2 0.021473779 0.036412132 0.0476929324 0.005479014 0.022496840
## studyID3 -0.012316132 -0.002824462 -0.0171835784 0.002747747 -0.010262558
## studyID4 0.009843343 0.008656643 -0.0009193841 0.017702681 0.009665479
## [,406] [,407] [,408] [,409] [,410]
## (Intercept) 0.762601546 0.74219286 0.770581870 0.690384114 0.671941040
## studyID1 0.003899860 -0.01474699 0.002412422 0.002392920 -0.009636869
## studyID2 0.025324134 0.05074244 0.040235479 0.026611918 0.025047817
## studyID3 -0.014008901 -0.01628549 -0.010066186 -0.014124800 -0.007849379
## studyID4 0.005520296 0.00267536 -0.004996819 0.007844341 0.017771457
## [,411] [,412] [,413] [,414] [,415]
## (Intercept) 0.740360002 0.796809087 0.8013272265 0.8195228755 0.747988254
## studyID1 -0.022011699 0.009192603 0.0042903082 -0.0089749669 -0.003439844
## studyID2 0.019534721 0.057394822 0.0190814095 0.0263961208 0.014352144
## studyID3 0.005356201 -0.035483514 -0.0112904114 0.0022698321 0.002052297
## studyID4 0.015562464 -0.002043839 0.0008857228 0.0008854724 0.002267234
## [,416] [,417] [,418] [,419]
## (Intercept) 0.765458777 9.108409e-01 0.7434750543 0.7462837419
## studyID1 0.010097546 -3.454646e-05 -0.0104254200 -0.0079905459
## studyID2 0.039230663 2.814095e-03 0.0009649118 0.0321392238
## studyID3 -0.026069869 9.926949e-04 0.0101085686 -0.0085420000
## studyID4 -0.003183555 2.616405e-03 0.0162487291 0.0002183858
## [,420] [,421] [,422] [,423] [,424]
## (Intercept) 0.8064795948 0.729059806 0.74253320 0.815456131 0.68228753
## studyID1 0.0006683436 0.008159932 -0.02315061 -0.023257366 -0.00434303
## studyID2 0.0275773698 0.032255169 0.02879712 0.034213824 0.02120583
## studyID3 -0.0091817867 -0.029552636 0.00486129 0.001352285 -0.00139535
## studyID4 -0.0049890226 0.012194012 0.00371496 0.006958200 0.01812044
## [,425] [,426] [,427] [,428] [,429]
## (Intercept) 0.805307322 0.734386484 0.781226245 0.761165050 0.878454343
## studyID1 0.001437475 -0.007858809 -0.006729342 -0.019770131 0.004773594
## studyID2 0.037213726 0.008161638 0.035190892 0.009704037 0.017337851
## studyID3 -0.027961952 0.001408674 -0.014409932 0.012723692 -0.004890089
## studyID4 0.017577635 0.016228997 0.006975959 0.009681297 -0.004625416
## [,430] [,431] [,432] [,433] [,434]
## (Intercept) 0.7307408671 0.860004564 0.813869033 0.80891772 0.695473668
## studyID1 -0.0103155050 -0.008985491 -0.004288582 -0.01408726 0.002662068
## studyID2 0.0594581026 0.012526535 0.041195006 -0.02141825 0.042187337
## studyID3 -0.0218318917 0.005422033 -0.006072954 0.01809023 -0.026110627
## studyID4 -0.0006147559 -0.006442050 -0.015920535 0.02118352 0.015255399
## [,435] [,436] [,437] [,438] [,439]
## (Intercept) 0.767816696 0.834690548 0.712820326 0.790623014 0.78139206
## studyID1 0.004230099 -0.003446216 -0.009836385 0.006727469 -0.01649439
## studyID2 0.019695870 0.016131635 0.035739901 0.012223476 -0.00341373
## studyID3 -0.007003105 -0.004229382 -0.003014796 -0.011539536 0.01747759
## studyID4 0.004066521 -0.006294865 0.001390425 0.010295257 0.01005324
## [,440] [,441] [,442] [,443] [,444]
## (Intercept) 0.8382449767 0.739558494 0.80501721 0.789004524 0.815258341
## studyID1 -0.0143186290 0.004776795 0.01472027 -0.009176973 -0.002652491
## studyID2 0.0309092993 0.027085929 0.03884960 0.025754300 0.015214227
## studyID3 0.0025691306 -0.020826238 -0.03031913 -0.007780553 -0.001632993
## studyID4 -0.0003587157 0.019073101 -0.01331290 0.013950478 -0.001105710
## [,445] [,446] [,447] [,448] [,449]
## (Intercept) 0.707597797 0.692515479 0.856142457 0.8230343600 0.705722715
## studyID1 0.006872203 -0.010662758 0.009463953 -0.0037503665 0.004018798
## studyID2 0.028839726 0.036292880 0.012530651 0.0040287564 0.051392326
## studyID3 -0.017059182 -0.001598780 -0.005149083 0.0010587117 -0.025829884
## studyID4 0.006420270 0.004082861 -0.003678858 0.0008684521 0.006007116
## [,450] [,451] [,452] [,453] [,454]
## (Intercept) 0.679298066 0.8040683995 0.8507621395 0.707710844 0.764759753
## studyID1 -0.003262513 -0.0044505480 -0.0004305181 -0.019443110 -0.005937593
## studyID2 0.048308057 0.0472037342 0.0303869261 0.062106855 0.004578184
## studyID3 -0.021489293 -0.0246711512 -0.0096688036 -0.015473780 -0.004877877
## studyID4 0.003805476 0.0003633028 -0.0112932601 0.009669232 0.018794467
## [,455] [,456] [,457] [,458] [,459]
## (Intercept) 0.6881339740 0.703262500 0.758553121 0.666758162 0.764273425
## studyID1 -0.0040755684 -0.005972377 0.008243575 -0.005117388 0.007737244
## studyID2 0.0117048080 0.007281159 0.019061575 0.034031899 0.021447596
## studyID3 0.0001985624 0.005270217 -0.012741783 -0.017839800 -0.026036519
## studyID4 0.0189494874 0.008584449 0.001578167 0.018837433 0.023770956
## [,460] [,461] [,462] [,463] [,464]
## (Intercept) 0.713289510 0.717676614 0.74464401 6.674934e-01 0.838080838
## studyID1 -0.002186158 -0.001323369 -0.01002129 -7.357679e-06 0.001270805
## studyID2 0.022900712 0.055481491 0.04128899 2.040015e-02 0.017946107
## studyID3 -0.006805072 -0.024232659 -0.01954586 -8.904418e-03 -0.011155499
## studyID4 0.009581682 0.004587466 0.01045013 1.211212e-02 0.001955436
## [,465] [,466] [,467] [,468] [,469]
## (Intercept) 0.81327877 0.7592964541 0.7024178344 0.735248049 0.9016905668
## studyID1 -0.01720657 -0.0051347691 0.0006875091 -0.001343420 -0.0005612865
## studyID2 -0.01592981 0.0315486495 0.0539687063 0.032993718 0.0124863167
## studyID3 0.02165895 -0.0114586705 -0.0247281886 -0.015292393 -0.0018360856
## studyID4 0.02467549 -0.0004493126 0.0032756004 0.009862528 0.0011094607
## [,470] [,471] [,472] [,473] [,474]
## (Intercept) 0.788012225 0.666412940 0.725603142 0.760205143 0.8124106961
## studyID1 0.001221940 -0.013559332 0.002715747 -0.019382993 -0.0027795973
## studyID2 0.053930772 0.033754416 0.044842496 0.032086259 0.0036171610
## studyID3 -0.034806451 -0.008174662 -0.016429116 -0.004856430 0.0005786069
## studyID4 0.007112951 0.017631126 0.001459992 0.001603706 0.0040677905
## [,475] [,476] [,477] [,478] [,479]
## (Intercept) 0.738185129 6.707013e-01 0.8779150059 0.72971486 0.722235515
## studyID1 0.011580995 5.608911e-05 -0.0001487249 -0.01218645 -0.007081269
## studyID2 0.018044954 1.371883e-02 0.0247157633 0.04109511 0.017288339
## studyID3 -0.014452036 -3.359379e-03 -0.0048074380 -0.01599097 -0.002436561
## studyID4 0.008199699 1.723358e-02 -0.0038984745 0.01099600 0.013927361
## [,480] [,481] [,482] [,483] [,484]
## (Intercept) 0.7287539256 0.733355142 0.739219125 0.729911534 0.719257334
## studyID1 0.0003790436 -0.017058888 0.013996134 0.002119248 0.001454618
## studyID2 0.0219775611 0.049962901 -0.015259599 0.038309114 -0.005919439
## studyID3 -0.0087574069 -0.009364566 0.001839821 -0.028708108 0.009127846
## studyID4 0.0045839307 -0.005642061 0.012832413 0.011133208 0.014887397
## [,485] [,486] [,487] [,488] [,489]
## (Intercept) 0.739123153 0.729293184 0.71997552 0.76170853 0.752974886
## studyID1 -0.007172758 -0.008849977 -0.01366556 0.01284209 -0.017653239
## studyID2 0.012593730 0.036072951 -0.01055463 0.04021083 0.022984164
## studyID3 0.001124255 -0.015323300 0.02320925 -0.03568843 0.007293243
## studyID4 0.006110792 0.015425259 0.01599019 0.01572843 0.008305248
## [,490] [,491] [,492] [,493] [,494]
## (Intercept) 0.734999932 0.729201509 0.855997954 0.747118713 0.866036075
## studyID1 0.008298873 0.002214227 0.008075246 0.004860696 0.003970276
## studyID2 -0.009811013 0.033249461 0.035988398 -0.001044022 0.014333070
## studyID3 -0.004006637 -0.023261132 -0.014126389 -0.004863520 -0.011349516
## studyID4 0.017470049 0.002023611 -0.012399299 0.016331584 0.004774524
## [,495] [,496] [,497] [,498] [,499]
## (Intercept) 0.845710180 0.7752397485 0.740975006 0.73244619 0.731012115
## studyID1 0.004982912 0.0000867685 -0.020659012 -0.02060080 -0.013523043
## studyID2 0.053894524 0.0388487723 0.047215761 0.01512713 0.016061377
## studyID3 -0.022277472 -0.0225976126 -0.003328574 0.00958496 0.003902584
## studyID4 -0.008856313 0.0067817641 0.002671420 0.01545056 0.011079975
## [,500] [,501] [,502] [,503] [,504]
## (Intercept) 0.75607015 0.815528830 0.698679277 0.696288033 0.765837806
## studyID1 0.01779104 -0.005744996 -0.003671693 -0.010463457 -0.019499560
## studyID2 0.04916250 0.028664038 0.010877126 0.031072026 0.026697455
## studyID3 -0.02176562 -0.006064168 -0.003844103 0.002770372 0.005440027
## studyID4 -0.02120934 -0.006663118 0.016826287 0.009145293 0.002172838
## [,505] [,506] [,507] [,508] [,509]
## (Intercept) 0.732547784 0.756286493 0.765085056 0.719299476 0.7979813347
## studyID1 -0.008878886 0.004395466 0.005891680 -0.002222290 0.0000927994
## studyID2 0.020361721 0.040065335 0.026168113 0.016946337 0.0465892543
## studyID3 -0.011651776 -0.024761472 -0.013506135 -0.007513363 -0.0197074534
## studyID4 0.026647361 0.004609552 0.004812506 0.011556894 0.0019153178
## [,510] [,511] [,512] [,513] [,514]
## (Intercept) 0.730241311 0.7311674895 0.666073607 0.7559136047 0.749647339
## studyID1 0.008203234 0.0067791422 0.003633387 -0.0005662212 0.002439108
## studyID2 -0.005272436 0.0051074246 0.020373766 0.0346980258 0.038435907
## studyID3 -0.004557812 -0.0001809931 -0.003015167 -0.0136964259 -0.019789265
## studyID4 0.011974007 0.0090819716 0.002570584 -0.0034005208 0.004387057
## [,515] [,516] [,517] [,518] [,519]
## (Intercept) 0.757776597 0.7446268022 0.740183346 0.723789445 0.7993721172
## studyID1 -0.005576760 -0.0001250055 -0.005836392 -0.005103726 0.0038224415
## studyID2 0.039989306 0.0369357886 0.046641742 0.020554812 0.0215897356
## studyID3 -0.014746036 -0.0211907717 -0.019665740 -0.004973822 -0.0032292348
## studyID4 -0.001527828 0.0181753911 0.001381521 0.014713292 -0.0008584309
## [,520] [,521] [,522] [,523] [,524]
## (Intercept) 0.7602932351 0.740186380 0.685929462 0.857498449 0.7217006141
## studyID1 -0.0058339256 0.008768004 -0.005617446 0.002822985 0.0062929736
## studyID2 0.0286660310 -0.023679747 0.023947382 0.026907491 0.0004665587
## studyID3 0.0004149877 0.003929701 -0.004142349 -0.008176753 -0.0111721169
## studyID4 0.0046170819 0.018733658 0.010389785 -0.003475193 0.0222254052
## [,525] [,526] [,527] [,528] [,529]
## (Intercept) 0.729558518 0.700254965 0.7834455595 0.755201398 7.245888e-01
## studyID1 0.005910384 -0.007242367 -0.0005705704 -0.001863562 -9.188805e-04
## studyID2 0.001893990 0.025396320 0.0113768987 0.045225724 5.633791e-02
## studyID3 -0.005760895 -0.007606875 -0.0055255304 -0.023332384 -1.958327e-02
## studyID4 0.017146715 0.011554195 0.0112848967 -0.007781563 -9.773214e-05
## [,530] [,531] [,532] [,533] [,534]
## (Intercept) 0.73169272 0.749051799 0.695334086 0.794041586 0.715482332
## studyID1 -0.01052617 0.018130374 0.002319407 0.007257925 -0.003199723
## studyID2 0.01400751 -0.004852596 0.055096285 0.049866169 0.024013747
## studyID3 0.01238458 -0.001129044 -0.024657342 -0.024413994 -0.010483875
## studyID4 0.00502881 0.001771097 -0.001180600 -0.003631591 0.010813387
## [,535] [,536] [,537] [,538] [,539]
## (Intercept) 0.696517321 0.720326785 0.820623159 0.704713280 0.712254312
## studyID1 0.008287417 -0.001888035 0.007814273 -0.005957089 -0.007414418
## studyID2 0.019910885 0.022762906 -0.001992353 0.049600754 0.020101320
## studyID3 -0.014960677 -0.011086342 -0.006649365 -0.027169777 -0.002754688
## studyID4 0.016557164 0.004093210 0.007155555 0.012900894 0.009950113
## [,540] [,541] [,542] [,543] [,544]
## (Intercept) 0.700574314 0.782798230 0.7903860293 0.691707218 0.729073055
## studyID1 -0.003610488 0.005244895 0.0138074741 0.003027384 0.006718914
## studyID2 0.014977125 0.027526654 0.0074167926 0.029785638 0.001977461
## studyID3 0.001326210 -0.022265420 -0.0068876057 -0.021526301 0.004911451
## studyID4 0.006836494 0.018126205 0.0002096535 0.014584323 0.006938888
## [,545] [,546] [,547] [,548] [,549]
## (Intercept) 0.689284835 0.783755239 0.759919024 0.734499160 0.701374890
## studyID1 0.004372489 0.008933483 0.007320188 0.006380790 0.001227324
## studyID2 0.032888898 -0.014632753 0.016070295 0.003249061 0.008842043
## studyID3 -0.012731817 0.001726027 -0.011401971 -0.001589066 0.004422731
## studyID4 0.004252754 0.009746351 -0.000855098 0.009471894 0.008931404
## [,550] [,551]
## (Intercept) 0.718612820 0.706794870
## studyID1 -0.012502062 0.012162939
## studyID2 0.019065867 -0.001342841
## studyID3 0.003107025 -0.007694686
## studyID4 0.009984655 0.013028090
##
## $f.perms
## [,1]
## [1,] 0.9445186
## [2,] 1.0300589
## [3,] 0.7577419
## [4,] 0.9838272
## [5,] 1.1329082
## [6,] 0.9736265
## [7,] 0.8297306
## [8,] 1.0504743
## [9,] 1.1596571
## [10,] 1.2704585
## [11,] 1.0358342
## [12,] 1.0163337
## [13,] 0.9510607
## [14,] 0.9790271
## [15,] 0.8759291
## [16,] 0.7533057
## [17,] 0.9726408
## [18,] 1.0499789
## [19,] 1.0360795
## [20,] 0.9205941
## [21,] 1.0935521
## [22,] 0.9347991
## [23,] 1.2591567
## [24,] 1.0745710
## [25,] 1.1308958
## [26,] 0.8104174
## [27,] 1.0352467
## [28,] 1.0166114
## [29,] 0.9082586
## [30,] 1.1303435
## [31,] 0.9338527
## [32,] 1.0038129
## [33,] 1.0140337
## [34,] 0.9884395
## [35,] 1.0644072
## [36,] 1.0940226
## [37,] 1.2532387
## [38,] 1.0006178
## [39,] 1.0467675
## [40,] 1.0651097
## [41,] 0.9907811
## [42,] 1.0101858
## [43,] 1.1481895
## [44,] 0.7929837
## [45,] 0.8892050
## [46,] 0.8728790
## [47,] 1.1382858
## [48,] 0.9984975
## [49,] 0.9810080
## [50,] 0.9026261
## [51,] 0.8593747
## [52,] 0.9261952
## [53,] 0.8001657
## [54,] 0.9436790
## [55,] 1.3467255
## [56,] 1.1006462
## [57,] 1.0166155
## [58,] 0.9935065
## [59,] 1.0386431
## [60,] 0.9782206
## [61,] 1.1274727
## [62,] 0.8460009
## [63,] 1.1879003
## [64,] 0.9552351
## [65,] 1.1936171
## [66,] 0.8317134
## [67,] 0.9597168
## [68,] 1.1065728
## [69,] 1.0277011
## [70,] 0.8935882
## [71,] 0.9172495
## [72,] 0.9347099
## [73,] 1.0631760
## [74,] 1.0777895
## [75,] 1.1040310
## [76,] 0.9559525
## [77,] 1.1005651
## [78,] 0.9655506
## [79,] 1.1132601
## [80,] 0.9944045
## [81,] 1.1628311
## [82,] 0.9500748
## [83,] 1.1237832
## [84,] 0.8438585
## [85,] 0.9251756
## [86,] 1.0395247
## [87,] 0.9996653
## [88,] 0.8793906
## [89,] 1.2919699
## [90,] 1.0499082
## [91,] 1.1383377
## [92,] 1.1173318
## [93,] 0.9590719
## [94,] 0.9764467
## [95,] 1.0219737
## [96,] 0.6890842
## [97,] 0.8081056
## [98,] 1.0724012
## [99,] 0.9641644
## [100,] 0.7650454
## [101,] 1.0266266
## [102,] 0.8830693
## [103,] 0.8986706
## [104,] 0.9372004
## [105,] 1.0957224
## [106,] 1.0084951
## [107,] 1.0240421
## [108,] 1.0175980
## [109,] 0.8979771
## [110,] 1.1063376
## [111,] 1.0387899
## [112,] 1.0775399
## [113,] 0.9742717
## [114,] 1.1523613
## [115,] 0.9388026
## [116,] 0.8931274
## [117,] 1.0329783
## [118,] 0.7215612
## [119,] 0.8449568
## [120,] 0.8202372
## [121,] 1.2001336
## [122,] 0.7184483
## [123,] 1.0065315
## [124,] 0.9760196
## [125,] 0.9098074
## [126,] 0.9881545
## [127,] 0.8299742
## [128,] 0.9619700
## [129,] 0.7354582
## [130,] 0.9894278
## [131,] 0.9838151
## [132,] 1.0704426
## [133,] 1.0849298
## [134,] 0.9147634
## [135,] 1.0907662
## [136,] 0.8547831
## [137,] 0.9676857
## [138,] 0.8606514
## [139,] 0.8599530
## [140,] 0.8805097
## [141,] 0.9403163
## [142,] 0.8495856
## [143,] 1.3039545
## [144,] 1.0756368
## [145,] 1.0646149
## [146,] 1.2151678
## [147,] 1.1753945
## [148,] 1.3144083
## [149,] 1.0524341
## [150,] 1.0925135
## [151,] 1.1124285
## [152,] 1.0654832
## [153,] 1.0992625
## [154,] 1.0826024
## [155,] 1.1584912
## [156,] 1.0323217
## [157,] 0.9949266
## [158,] 1.1375530
## [159,] 0.8691367
## [160,] 0.9706782
## [161,] 1.2349803
## [162,] 1.1446092
## [163,] 1.0971425
## [164,] 1.2454526
## [165,] 0.7836918
## [166,] 1.1712708
## [167,] 1.3349896
## [168,] 1.1574639
## [169,] 0.9621006
## [170,] 1.0982658
## [171,] 1.0294558
## [172,] 1.0736767
## [173,] 0.7930411
## [174,] 1.0702476
## [175,] 0.9637821
## [176,] 1.0018850
## [177,] 1.0308995
## [178,] 0.8991994
## [179,] 1.1464698
## [180,] 1.0510749
## [181,] 1.0690708
## [182,] 0.9376931
## [183,] 0.8730615
## [184,] 1.0114215
## [185,] 1.2850856
## [186,] 0.7836709
## [187,] 1.0386710
## [188,] 0.8604912
## [189,] 1.0928745
## [190,] 0.8208338
## [191,] 1.0928538
## [192,] 1.0995170
## [193,] 1.0336508
## [194,] 0.9812785
## [195,] 1.1411563
## [196,] 0.9530529
## [197,] 0.9215094
## [198,] 0.8182782
## [199,] 0.8937496
## [200,] 0.9765289
## [201,] 1.3439210
## [202,] 1.0941596
## [203,] 1.2543212
## [204,] 0.9963889
## [205,] 0.9117349
## [206,] 0.9341795
## [207,] 0.9514214
## [208,] 1.3025507
## [209,] 1.1091625
## [210,] 1.0165828
## [211,] 1.0745285
## [212,] 1.0832150
## [213,] 1.1002792
## [214,] 0.7760277
## [215,] 1.0002701
## [216,] 0.9661197
## [217,] 0.9186577
## [218,] 0.9508141
## [219,] 1.2454270
## [220,] 1.0053841
## [221,] 1.1708748
## [222,] 1.0142230
## [223,] 0.9199088
## [224,] 0.8718801
## [225,] 0.9610293
## [226,] 1.0460001
## [227,] 0.8011922
## [228,] 0.8794024
## [229,] 1.0145610
## [230,] 0.9248179
## [231,] 1.2148253
## [232,] 1.1302971
## [233,] 1.2067115
## [234,] 0.8979050
## [235,] 1.2483100
## [236,] 1.0039978
## [237,] 1.3334866
## [238,] 1.1548700
## [239,] 0.9462150
## [240,] 1.4208228
## [241,] 0.8992884
## [242,] 0.8678202
## [243,] 0.8885423
## [244,] 0.9933042
## [245,] 0.9657142
## [246,] 0.8736875
## [247,] 0.9077571
## [248,] 0.9170988
## [249,] 1.0274937
## [250,] 0.8494073
## [251,] 0.9260703
## [252,] 0.9806324
## [253,] 0.8926732
## [254,] 0.9543288
## [255,] 1.0142968
## [256,] 1.0383428
## [257,] 1.0447059
## [258,] 1.0631531
## [259,] 0.9762302
## [260,] 0.8774756
## [261,] 1.1130266
## [262,] 1.0308571
## [263,] 1.0329332
## [264,] 0.9693406
## [265,] 0.8658019
## [266,] 0.9262437
## [267,] 0.8515991
## [268,] 0.9471203
## [269,] 1.0095325
## [270,] 1.0529227
## [271,] 1.0788233
## [272,] 0.8407514
## [273,] 1.0061171
## [274,] 0.9020359
## [275,] 0.8901405
## [276,] 0.8777018
## [277,] 0.9565566
## [278,] 0.9414725
## [279,] 0.9562074
## [280,] 1.0425921
## [281,] 0.7895742
## [282,] 1.0149221
## [283,] 0.8492447
## [284,] 0.9087286
## [285,] 1.1202124
## [286,] 1.2511249
## [287,] 1.1475478
## [288,] 0.8723650
## [289,] 0.9524788
## [290,] 1.0720210
## [291,] 1.0937537
## [292,] 0.9433795
## [293,] 1.1119050
## [294,] 0.9573355
## [295,] 1.0543751
## [296,] 1.0142563
## [297,] 1.0360837
## [298,] 1.1284272
## [299,] 1.0612044
## [300,] 0.9030110
## [301,] 1.1256049
## [302,] 0.8278414
## [303,] 1.1579523
## [304,] 0.9468998
## [305,] 0.7404893
## [306,] 1.0309986
## [307,] 0.8678874
## [308,] 1.0388042
## [309,] 0.9344397
## [310,] 0.7887431
## [311,] 0.9478758
## [312,] 1.0742123
## [313,] 0.8446062
## [314,] 1.1399276
## [315,] 1.1540026
## [316,] 1.0484787
## [317,] 0.8206504
## [318,] 0.8453303
## [319,] 1.3023984
## [320,] 0.9213449
## [321,] 0.9439086
## [322,] 1.0414316
## [323,] 1.0531418
## [324,] 0.9480974
## [325,] 0.8971366
## [326,] 1.0928942
## [327,] 0.9803319
## [328,] 1.0498894
## [329,] 0.9003884
## [330,] 1.1140564
## [331,] 1.0484411
## [332,] 1.1448789
## [333,] 0.9826913
## [334,] 1.0209930
## [335,] 0.9350076
## [336,] 0.7877878
## [337,] 1.0362604
## [338,] 1.0396982
## [339,] 1.0857976
## [340,] 0.9589927
## [341,] 0.9865377
## [342,] 1.3454261
## [343,] 1.0707573
## [344,] 0.9503941
## [345,] 1.2010565
## [346,] 1.1117691
## [347,] 0.9219508
## [348,] 1.2241548
## [349,] 1.0296684
## [350,] 0.8574766
## [351,] 0.9289692
## [352,] 0.8463280
## [353,] 0.7447850
## [354,] 1.0198634
## [355,] 1.0191344
## [356,] 0.9160418
## [357,] 1.0074713
## [358,] 0.9088775
## [359,] 0.8369110
## [360,] 1.1905199
## [361,] 0.8572369
## [362,] 0.9959744
## [363,] 0.9561651
## [364,] 1.0110296
## [365,] 0.9566398
## [366,] 1.2067720
## [367,] 0.9598740
## [368,] 0.8802386
## [369,] 1.0859214
## [370,] 1.2363123
## [371,] 0.9630830
## [372,] 0.8731467
## [373,] 1.1307437
## [374,] 1.0873231
## [375,] 0.8716325
## [376,] 0.8090252
## [377,] 0.9075484
## [378,] 0.8857240
## [379,] 1.1101021
## [380,] 0.8767455
## [381,] 0.8111389
## [382,] 0.9148283
## [383,] 1.1142155
## [384,] 0.6363978
## [385,] 1.1105080
## [386,] 1.0882127
## [387,] 0.9320610
## [388,] 1.1541997
## [389,] 0.7909985
## [390,] 1.3771538
## [391,] 0.9338516
## [392,] 1.0447243
## [393,] 1.0287486
## [394,] 1.0146369
## [395,] 0.9113111
## [396,] 1.2049586
## [397,] 0.9449735
## [398,] 1.2228853
## [399,] 1.0466906
## [400,] 0.9247045
## [401,] 0.8443550
## [402,] 0.9407650
## [403,] 0.9529241
## [404,] 1.2251172
## [405,] 0.6837044
## [406,] 1.1271344
## [407,] 0.8891519
## [408,] 1.0506781
## [409,] 0.8947669
## [410,] 1.1303887
## [411,] 1.0551439
## [412,] 0.9151338
## [413,] 1.0715998
## [414,] 1.0696872
## [415,] 1.0175061
## [416,] 1.1108071
## [417,] 1.0596517
## [418,] 0.8251862
## [419,] 0.8802126
## [420,] 0.8700088
## [421,] 1.0109396
## [422,] 1.2650235
## [423,] 1.1379303
## [424,] 0.9300666
## [425,] 1.0381678
## [426,] 1.0262557
## [427,] 0.8316584
## [428,] 0.8578886
## [429,] 0.9604973
## [430,] 0.9184963
## [431,] 0.8594702
## [432,] 1.1185279
## [433,] 1.2369842
## [434,] 1.0191266
## [435,] 1.1720949
## [436,] 1.0997486
## [437,] 0.9562461
## [438,] 0.7625449
## [439,] 0.7237721
## [440,] 1.3056529
## [441,] 0.9229612
## [442,] 0.7785591
## [443,] 1.0522164
## [444,] 1.0335687
## [445,] 1.3586644
## [446,] 0.9975890
## [447,] 0.9140193
## [448,] 1.0958802
## [449,] 0.9599645
## [450,] 1.1303290
## [451,] 0.8080642
## [452,] 0.9575931
## [453,] 1.0018782
## [454,] 0.9767067
## [455,] 1.1032194
## [456,] 0.8553192
## [457,] 0.9839322
## [458,] 0.8485200
## [459,] 0.8680359
## [460,] 1.2541286
## [461,] 1.1357966
## [462,] 0.8443371
## [463,] 0.9929922
## [464,] 0.8637002
## [465,] 0.9149451
## [466,] 0.9551485
## [467,] 1.0821664
## [468,] 0.9269271
## [469,] 1.2018363
## [470,] 0.8926399
## [471,] 0.8920757
## [472,] 0.9732574
## [473,] 1.1624549
## [474,] 0.8915513
## [475,] 0.9852730
## [476,] 1.2067043
## [477,] 0.8949887
## [478,] 0.9355857
## [479,] 1.0651994
## [480,] 1.0314812
## [481,] 1.0065401
## [482,] 1.0416498
## [483,] 1.0254348
## [484,] 1.0256036
## [485,] 0.7758274
## [486,] 1.0355338
## [487,] 0.9959044
## [488,] 1.1785907
## [489,] 1.1359838
## [490,] 0.9734136
## [491,] 0.9517050
## [492,] 0.9942294
## [493,] 1.2907714
## [494,] 0.8897092
## [495,] 0.9690216
## [496,] 1.1223848
## [497,] 1.0743245
## [498,] 1.0827160
## [499,] 0.8656483
## [500,] 0.9373758
## [501,] 1.1190159
## [502,] 1.1317841
## [503,] 1.3019814
## [504,] 0.9733843
## [505,] 0.9055916
## [506,] 1.1750922
## [507,] 1.0959913
## [508,] 1.0457188
## [509,] 0.8998349
## [510,] 1.0922305
## [511,] 1.2984339
## [512,] 1.2937445
## [513,] 1.1737744
## [514,] 1.0574836
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## [558,] 1.1042648
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## [560,] 1.0482941
## [561,] 0.8708797
## [562,] 0.9313753
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## [646,] 0.9892730
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## [649,] 1.0756116
## [650,] 0.9170443
## [651,] 1.0133522
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## [653,] 0.6892257
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## [655,] 0.9282772
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## [694,] 1.1404132
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## [704,] 1.1576310
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## [731,] 1.3342075
## [732,] 0.9821886
## [733,] 0.8928925
## [734,] 0.8994471
## [735,] 0.9158751
## [736,] 0.8767494
## [737,] 0.8767426
## [738,] 1.0704968
## [739,] 1.0549714
## [740,] 1.2387169
## [741,] 0.9818874
## [742,] 0.8892011
## [743,] 0.9354418
## [744,] 0.7965230
## [745,] 0.8071315
## [746,] 0.9431561
## [747,] 0.8964851
## [748,] 1.1253455
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## [750,] 0.9822009
## [751,] 0.9073992
## [752,] 0.9509598
## [753,] 0.8490693
## [754,] 0.9377173
## [755,] 0.9573658
## [756,] 1.1646682
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## [775,] 1.0595381
## [776,] 0.8904814
## [777,] 0.9558447
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## [779,] 1.0084690
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## [781,] 1.0403878
## [782,] 1.1137030
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## [784,] 0.9873300
## [785,] 1.1595623
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## [793,] 0.8824236
## [794,] 1.2036303
## [795,] 1.1082178
## [796,] 0.9687702
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## [798,] 1.0022233
## [799,] 1.0242337
## [800,] 1.1819880
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## [802,] 1.1074139
## [803,] 1.2160546
## [804,] 0.9750016
## [805,] 1.0388773
## [806,] 1.2132606
## [807,] 1.4385104
## [808,] 0.9189769
## [809,] 1.3032293
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## [812,] 1.1827496
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## [814,] 0.8841279
## [815,] 1.0478059
## [816,] 0.8929074
## [817,] 1.1529456
## [818,] 0.9950255
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## [820,] 1.3193675
## [821,] 0.9556410
## [822,] 0.7497284
## [823,] 0.9576432
## [824,] 1.1578728
## [825,] 1.0599339
## [826,] 0.8850027
## [827,] 1.0038345
## [828,] 0.9612227
## [829,] 0.9123155
## [830,] 0.9954820
## [831,] 0.8772654
## [832,] 0.8977653
## [833,] 0.7356747
## [834,] 0.8820856
## [835,] 0.9761331
## [836,] 0.9197259
## [837,] 0.9360029
## [838,] 1.0823817
## [839,] 1.6413346
## [840,] 0.8953185
## [841,] 0.9145785
## [842,] 1.0421311
## [843,] 1.0086915
## [844,] 0.9311595
## [845,] 1.2246673
## [846,] 0.9497837
## [847,] 1.0411791
## [848,] 0.9066172
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## [850,] 1.0172111
## [851,] 1.1531680
## [852,] 0.9574548
## [853,] 0.8828255
## [854,] 0.9905216
## [855,] 0.8123100
## [856,] 0.8741538
## [857,] 1.2446310
## [858,] 0.7970211
## [859,] 1.1506009
## [860,] 1.0385538
## [861,] 0.8750722
## [862,] 1.1140172
## [863,] 1.1288998
## [864,] 1.0592727
## [865,] 1.0354316
## [866,] 1.0085421
## [867,] 1.1924875
## [868,] 1.0943690
## [869,] 1.1279740
## [870,] 0.9502809
## [871,] 0.9293917
## [872,] 0.8751399
## [873,] 0.8717723
## [874,] 1.0431797
## [875,] 0.8991331
## [876,] 0.9529267
## [877,] 1.1861286
## [878,] 0.9134123
## [879,] 0.8862132
## [880,] 0.9451999
## [881,] 0.7552522
## [882,] 1.2013873
## [883,] 0.8306264
## [884,] 0.8932184
## [885,] 0.9439608
## [886,] 1.1057048
## [887,] 0.9116979
## [888,] 1.1539709
## [889,] 0.8202278
## [890,] 1.2566932
## [891,] 1.0815505
## [892,] 0.9207209
## [893,] 1.1692328
## [894,] 0.9689254
## [895,] 1.0862689
## [896,] 0.8332018
## [897,] 0.9955144
## [898,] 0.9083232
## [899,] 0.8706462
## [900,] 1.0316144
## [901,] 1.0335255
## [902,] 0.9492367
## [903,] 1.0245916
## [904,] 1.0740753
## [905,] 1.2355049
## [906,] 0.9909833
## [907,] 0.9967832
## [908,] 1.0165833
## [909,] 0.8089366
## [910,] 0.9968348
## [911,] 1.0171154
## [912,] 1.0663452
## [913,] 1.1497034
## [914,] 1.0348742
## [915,] 1.1314115
## [916,] 1.1416691
## [917,] 1.0483664
## [918,] 0.9274644
## [919,] 0.8699388
## [920,] 1.0768107
## [921,] 0.8943522
## [922,] 1.0136148
## [923,] 1.0304540
## [924,] 1.3698700
## [925,] 0.8977905
## [926,] 1.1249392
## [927,] 0.8658799
## [928,] 0.6945398
## [929,] 1.1174848
## [930,] 0.8122921
## [931,] 0.8461014
## [932,] 0.9146932
## [933,] 1.1926854
## [934,] 0.9328369
## [935,] 1.1639487
## [936,] 1.3194992
## [937,] 0.8331006
## [938,] 0.8987855
## [939,] 1.0374385
## [940,] 1.1287559
## [941,] 1.1960575
## [942,] 0.8692656
## [943,] 0.9421606
## [944,] 1.1154481
## [945,] 1.1374266
## [946,] 1.2737639
## [947,] 1.0663805
## [948,] 1.1094580
## [949,] 0.7367192
## [950,] 0.9765049
## [951,] 0.8582548
## [952,] 1.0088624
## [953,] 0.9180028
## [954,] 1.1608820
## [955,] 1.0347400
## [956,] 0.8681405
## [957,] 1.3823450
## [958,] 1.3221606
## [959,] 1.1111119
## [960,] 0.9991067
## [961,] 1.0434223
## [962,] 0.7855121
## [963,] 1.0081282
## [964,] 0.9942141
## [965,] 1.0960640
## [966,] 1.0051815
## [967,] 1.0267158
## [968,] 0.8129942
## [969,] 1.1929213
## [970,] 1.1387943
## [971,] 0.9218115
## [972,] 0.9290550
## [973,] 1.0810521
## [974,] 1.0350116
## [975,] 0.9299208
## [976,] 0.9074611
## [977,] 0.9848944
## [978,] 1.1291229
## [979,] 1.0107476
## [980,] 1.1022846
## [981,] 0.8765397
## [982,] 1.1023894
## [983,] 0.8482816
## [984,] 1.0913779
## [985,] 1.1293391
## [986,] 0.8693216
## [987,] 0.9138140
## [988,] 0.8768224
## [989,] 0.9733781
## [990,] 1.1087161
## [991,] 0.8583398
## [992,] 1.0105472
## [993,] 0.9725355
## [994,] 1.0444395
## [995,] 1.0243848
## [996,] 0.8766507
## [997,] 0.8066102
## [998,] 0.9142622
## [999,] 0.8239225
##
## $model.matrix
## (Intercept)
## FengQ_2015.metaphlan_bugs_list.stool:SID31004 1
## FengQ_2015.metaphlan_bugs_list.stool:SID31009 1
## FengQ_2015.metaphlan_bugs_list.stool:SID31021 1
## FengQ_2015.metaphlan_bugs_list.stool:SID31071 1
## FengQ_2015.metaphlan_bugs_list.stool:SID31112 1
## FengQ_2015.metaphlan_bugs_list.stool:SID31129 1
## FengQ_2015.metaphlan_bugs_list.stool:SID31159 1
## FengQ_2015.metaphlan_bugs_list.stool:SID31160 1
## FengQ_2015.metaphlan_bugs_list.stool:SID31188 1
## FengQ_2015.metaphlan_bugs_list.stool:SID31219 1
## FengQ_2015.metaphlan_bugs_list.stool:SID31223 1
## FengQ_2015.metaphlan_bugs_list.stool:SID31236 1
## FengQ_2015.metaphlan_bugs_list.stool:SID31237 1
## FengQ_2015.metaphlan_bugs_list.stool:SID31267 1
## FengQ_2015.metaphlan_bugs_list.stool:SID31276 1
## FengQ_2015.metaphlan_bugs_list.stool:SID31285 1
## FengQ_2015.metaphlan_bugs_list.stool:SID31300 1
## FengQ_2015.metaphlan_bugs_list.stool:SID31328 1
## FengQ_2015.metaphlan_bugs_list.stool:SID31333 1
## FengQ_2015.metaphlan_bugs_list.stool:SID31343 1
## FengQ_2015.metaphlan_bugs_list.stool:SID31360 1
## FengQ_2015.metaphlan_bugs_list.stool:SID31367 1
## FengQ_2015.metaphlan_bugs_list.stool:SID31379 1
## FengQ_2015.metaphlan_bugs_list.stool:SID31416 1
## FengQ_2015.metaphlan_bugs_list.stool:SID31428 1
## FengQ_2015.metaphlan_bugs_list.stool:SID31446 1
## FengQ_2015.metaphlan_bugs_list.stool:SID31450 1
## FengQ_2015.metaphlan_bugs_list.stool:SID31452 1
## FengQ_2015.metaphlan_bugs_list.stool:SID31489 1
## FengQ_2015.metaphlan_bugs_list.stool:SID31493 1
## FengQ_2015.metaphlan_bugs_list.stool:SID31512 1
## FengQ_2015.metaphlan_bugs_list.stool:SID31519 1
## FengQ_2015.metaphlan_bugs_list.stool:SID31537 1
## FengQ_2015.metaphlan_bugs_list.stool:SID31549 1
## FengQ_2015.metaphlan_bugs_list.stool:SID31557 1
## FengQ_2015.metaphlan_bugs_list.stool:SID31637 1
## FengQ_2015.metaphlan_bugs_list.stool:SID31685 1
## FengQ_2015.metaphlan_bugs_list.stool:SID31700 1
## FengQ_2015.metaphlan_bugs_list.stool:SID31711 1
## FengQ_2015.metaphlan_bugs_list.stool:SID31714 1
## FengQ_2015.metaphlan_bugs_list.stool:SID31723 1
## FengQ_2015.metaphlan_bugs_list.stool:SID31749 1
## FengQ_2015.metaphlan_bugs_list.stool:SID31750 1
## FengQ_2015.metaphlan_bugs_list.stool:SID31766 1
## FengQ_2015.metaphlan_bugs_list.stool:SID31865 1
## FengQ_2015.metaphlan_bugs_list.stool:SID31866 1
## FengQ_2015.metaphlan_bugs_list.stool:SID31868 1
## FengQ_2015.metaphlan_bugs_list.stool:SID31870 1
## FengQ_2015.metaphlan_bugs_list.stool:SID31871 1
## FengQ_2015.metaphlan_bugs_list.stool:SID31872 1
## FengQ_2015.metaphlan_bugs_list.stool:SID31873 1
## FengQ_2015.metaphlan_bugs_list.stool:SID31874 1
## FengQ_2015.metaphlan_bugs_list.stool:SID31875 1
## FengQ_2015.metaphlan_bugs_list.stool:SID31876 1
## FengQ_2015.metaphlan_bugs_list.stool:SID31877 1
## FengQ_2015.metaphlan_bugs_list.stool:SID31878 1
## FengQ_2015.metaphlan_bugs_list.stool:SID31879 1
## FengQ_2015.metaphlan_bugs_list.stool:SID31880 1
## FengQ_2015.metaphlan_bugs_list.stool:SID31881 1
## FengQ_2015.metaphlan_bugs_list.stool:SID31883 1
## FengQ_2015.metaphlan_bugs_list.stool:SID31884 1
## FengQ_2015.metaphlan_bugs_list.stool:SID530050 1
## FengQ_2015.metaphlan_bugs_list.stool:SID530052 1
## FengQ_2015.metaphlan_bugs_list.stool:SID530055 1
## FengQ_2015.metaphlan_bugs_list.stool:SID530074 1
## FengQ_2015.metaphlan_bugs_list.stool:SID530075 1
## FengQ_2015.metaphlan_bugs_list.stool:SID530119 1
## FengQ_2015.metaphlan_bugs_list.stool:SID530154 1
## FengQ_2015.metaphlan_bugs_list.stool:SID530163 1
## FengQ_2015.metaphlan_bugs_list.stool:SID530167 1
## FengQ_2015.metaphlan_bugs_list.stool:SID530177 1
## FengQ_2015.metaphlan_bugs_list.stool:SID530215 1
## FengQ_2015.metaphlan_bugs_list.stool:SID530227 1
## FengQ_2015.metaphlan_bugs_list.stool:SID530251 1
## FengQ_2015.metaphlan_bugs_list.stool:SID530258 1
## FengQ_2015.metaphlan_bugs_list.stool:SID530295 1
## FengQ_2015.metaphlan_bugs_list.stool:SID530315 1
## FengQ_2015.metaphlan_bugs_list.stool:SID530331 1
## FengQ_2015.metaphlan_bugs_list.stool:SID530364 1
## FengQ_2015.metaphlan_bugs_list.stool:SID530368 1
## FengQ_2015.metaphlan_bugs_list.stool:SID530373 1
## FengQ_2015.metaphlan_bugs_list.stool:SID530394 1
## FengQ_2015.metaphlan_bugs_list.stool:SID530444 1
## FengQ_2015.metaphlan_bugs_list.stool:SID530451 1
## FengQ_2015.metaphlan_bugs_list.stool:SID530890 1
## FengQ_2015.metaphlan_bugs_list.stool:SID531128 1
## FengQ_2015.metaphlan_bugs_list.stool:SID531155 1
## FengQ_2015.metaphlan_bugs_list.stool:SID531248 1
## FengQ_2015.metaphlan_bugs_list.stool:SID531274 1
## FengQ_2015.metaphlan_bugs_list.stool:SID531277 1
## FengQ_2015.metaphlan_bugs_list.stool:SID531281 1
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## YuJ_2015.metaphlan_bugs_list.stool:SZAXPI017460-27 1
## YuJ_2015.metaphlan_bugs_list.stool:SZAXPI017461-32 1
## YuJ_2015.metaphlan_bugs_list.stool:SZAXPI017462-33 1
## YuJ_2015.metaphlan_bugs_list.stool:SZAXPI017463-36 1
## YuJ_2015.metaphlan_bugs_list.stool:SZAXPI017464-37 1
## YuJ_2015.metaphlan_bugs_list.stool:SZAXPI017465-43 1
## YuJ_2015.metaphlan_bugs_list.stool:SZAXPI017466-84 1
## YuJ_2015.metaphlan_bugs_list.stool:SZAXPI017467-87 1
## YuJ_2015.metaphlan_bugs_list.stool:SZAXPI017468-88 1
## YuJ_2015.metaphlan_bugs_list.stool:SZAXPI017580-90 1
## YuJ_2015.metaphlan_bugs_list.stool:SZAXPI017581-93 1
## YuJ_2015.metaphlan_bugs_list.stool:SZAXPI017582-94 1
## YuJ_2015.metaphlan_bugs_list.stool:SZAXPI017583-102 1
## YuJ_2015.metaphlan_bugs_list.stool:SZAXPI017584-108 1
## YuJ_2015.metaphlan_bugs_list.stool:SZAXPI017585-109 1
## YuJ_2015.metaphlan_bugs_list.stool:SZAXPI017586-111 1
## YuJ_2015.metaphlan_bugs_list.stool:SZAXPI017587-113 1
## YuJ_2015.metaphlan_bugs_list.stool:SZAXPI017588-123 1
## YuJ_2015.metaphlan_bugs_list.stool:SZAXPI017589-133 1
## YuJ_2015.metaphlan_bugs_list.stool:SZAXPI017590-136 1
## YuJ_2015.metaphlan_bugs_list.stool:SZAXPI017591-140 1
## YuJ_2015.metaphlan_bugs_list.stool:SZAXPI017592-142 1
## YuJ_2015.metaphlan_bugs_list.stool:SZAXPI017593-158 1
## YuJ_2015.metaphlan_bugs_list.stool:SZAXPI017594-166 1
## YuJ_2015.metaphlan_bugs_list.stool:SZAXPI017595-169 1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS00146684ST-4-0 1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS00281083ST-3-0 1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS02124300ST-4-0 1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS02379307ST-4-0 1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS02856720ST-4-0 1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS03473770ST-4-0 1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS03857607ST-4-0 1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS05314658ST-4-0 1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS06260551ST-3-0 1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS07277498ST-4-0 1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS07539127ST-4-0 1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS07648107ST-4-0 1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS09568613ST-4-0 1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS10706551ST-3-0 1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS11015875ST-4-0 1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS11354283ST-4-0 1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS11362406ST-4-0 1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS11558985ST-4-0 1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS12370844ST-4-0 1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS12656533ST-4-0 1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS13047523ST-4-0 1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS14449628ST-4-0 1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS15704761ST-4-0 1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS15794887ST-4-0 1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS16326685ST-4-0 1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS16383318ST-4-0 1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS16561622ST-4-0 1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS17669415ST-4-0 1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS20795251ST-4-0 1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS21126322ST-4-0 1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS21278152ST-4-0 1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS22416007ST-4-0 1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS22958137ST-20-0 1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS23164343ST-4-0 1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS24254057ST-4-0 1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS27304052ST-3-0 1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS27927933ST-4-0 1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS29210128ST-4-0 1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS29688262ST-20-0 1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS32452666ST-4-0 1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS33816588ST-4-0 1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS34055159ST-4-0 1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS34604008ST-4-0 1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS35100175ST-4-0 1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS36699628ST-4-0 1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS36797902ST-4-0 1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS38765456ST-20-0 1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS40244499ST-3-0 1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS41222843ST-4-0 1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS41288781ST-4-0 1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS41548810ST-4-0 1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS41692898ST-4-0 1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS44093303ST-4-0 1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS44757994ST-4-0 1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS45571137ST-3-0 1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS45793747ST-4-0 1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS46047672ST-4-0 1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS46467422ST-4-0 1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS47284573ST-4-0 1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS48174381ST-4-0 1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS48725289ST-4-0 1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS50003399ST-4-0 1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS50148151ST-4-0 1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS50471204ST-4-0 1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS51595129ST-4-0 1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS52370277ST-4-0 1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS53043478ST-4-0 1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS53355328ST-4-0 1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS55230578ST-4-0 1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS58234805ST-4-0 1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS59132091ST-4-0 1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS61287323ST-4-0 1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS62605362ST-3-0 1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS62794166ST-4-0 1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS63448910ST-4-0 1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS63468405ST-4-0 1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS63910149ST-4-0 1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS64773582ST-4-0 1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS64785924ST-20-0 1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS65479369ST-4-0 1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS71301801ST-4-0 1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS71578391ST-4-0 1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS72607085ST-4-0 1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS74239020ST-4-0 1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS76845094ST-20-0 1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS77252613ST-4-0 1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS78100604ST-4-0 1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS78318719ST-4-0 1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS79210440ST-3-0 1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS80834637ST-4-0 1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS81139242ST-4-0 1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS81887263ST-4-0 1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS82146115ST-4-0 1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS82507866ST-3-0 1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS82944710ST-20-0 1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS83870198ST-4-0 1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS84543192ST-4-0 1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS85214191ST-3-0 1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS87116798ST-4-0 1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS87167916ST-4-0 1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS87252800ST-4-0 1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS87605453ST-4-0 1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS88007743ST-4-0 1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS88317640ST-4-0 1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS90164298ST-4-0 1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS91228662ST-4-0 1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS93040568ST-20-0 1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS94417875ST-3-0 1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS94603952ST-4-0 1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS95097901ST-4-0 1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS95409808ST-4-0 1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS98482370ST-3-0 1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS98512455ST-4-0 1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS98832363ST-4-0 1
## ZellerG_2014.metaphlan_bugs_list.stool:CCMD11006829ST-21-0 1
## ZellerG_2014.metaphlan_bugs_list.stool:CCMD12232071ST-21-0 1
## ZellerG_2014.metaphlan_bugs_list.stool:CCMD13071240ST-21-0 1
## ZellerG_2014.metaphlan_bugs_list.stool:CCMD13934959ST-21-0 1
## ZellerG_2014.metaphlan_bugs_list.stool:CCMD14479708ST-21-0 1
## ZellerG_2014.metaphlan_bugs_list.stool:CCMD18872694ST-21-0 1
## ZellerG_2014.metaphlan_bugs_list.stool:CCMD19497912ST-21-0 1
## ZellerG_2014.metaphlan_bugs_list.stool:CCMD23101338ST-21-0 1
## ZellerG_2014.metaphlan_bugs_list.stool:CCMD25511638ST-21-0 1
## ZellerG_2014.metaphlan_bugs_list.stool:CCMD25963797ST-21-0 1
## ZellerG_2014.metaphlan_bugs_list.stool:CCMD26709089ST-21-0 1
## ZellerG_2014.metaphlan_bugs_list.stool:CCMD26925580ST-21-0 1
## ZellerG_2014.metaphlan_bugs_list.stool:CCMD34381688ST-21-0 1
## ZellerG_2014.metaphlan_bugs_list.stool:CCMD35802077ST-21-0 1
## ZellerG_2014.metaphlan_bugs_list.stool:CCMD40701343ST-21-0 1
## ZellerG_2014.metaphlan_bugs_list.stool:CCMD42428553ST-21-0 1
## ZellerG_2014.metaphlan_bugs_list.stool:CCMD45988061ST-21-0 1
## ZellerG_2014.metaphlan_bugs_list.stool:CCMD46222674ST-21-0 1
## ZellerG_2014.metaphlan_bugs_list.stool:CCMD46947453ST-21-0 1
## ZellerG_2014.metaphlan_bugs_list.stool:CCMD48236717ST-21-0 1
## ZellerG_2014.metaphlan_bugs_list.stool:CCMD50071957ST-21-0 1
## ZellerG_2014.metaphlan_bugs_list.stool:CCMD51864103ST-21-0 1
## ZellerG_2014.metaphlan_bugs_list.stool:CCMD60079086ST-21-0 1
## ZellerG_2014.metaphlan_bugs_list.stool:CCMD63399960ST-21-0 1
## ZellerG_2014.metaphlan_bugs_list.stool:CCMD64503764ST-21-0 1
## ZellerG_2014.metaphlan_bugs_list.stool:CCMD64776337ST-21-0 1
## ZellerG_2014.metaphlan_bugs_list.stool:CCMD72895164ST-21-0 1
## ZellerG_2014.metaphlan_bugs_list.stool:CCMD74930188ST-21-0 1
## ZellerG_2014.metaphlan_bugs_list.stool:CCMD79987997ST-21-0 1
## ZellerG_2014.metaphlan_bugs_list.stool:CCMD82866709ST-21-0 1
## ZellerG_2014.metaphlan_bugs_list.stool:CCMD86114146ST-21-0 1
## ZellerG_2014.metaphlan_bugs_list.stool:CCMD86707194ST-21-0 1
## ZellerG_2014.metaphlan_bugs_list.stool:CCMD87156761ST-21-0 1
## ZellerG_2014.metaphlan_bugs_list.stool:CCMD88272491ST-21-0 1
## ZellerG_2014.metaphlan_bugs_list.stool:CCMD90311071ST-21-0 1
## ZellerG_2014.metaphlan_bugs_list.stool:CCMD93344354ST-21-0 1
## ZellerG_2014.metaphlan_bugs_list.stool:CCMD95433940ST-21-0 1
## ZellerG_2014.metaphlan_bugs_list.stool:CCMD96553385ST-21-0 1
## ZellerG_2014.metaphlan_bugs_list.stool:MMPU29365221ST 1
## ZellerG_2014.metaphlan_bugs_list.stool:MMPU68403337ST 1
## ZellerG_2014.metaphlan_bugs_list.stool:MMPU72854103ST 1
## ZellerG_2014.metaphlan_bugs_list.stool:MMPU84450604ST 1
## ZellerG_2014.metaphlan_bugs_list.stool:MMPU99077057ST 1
## studyID1
## FengQ_2015.metaphlan_bugs_list.stool:SID31004 1
## FengQ_2015.metaphlan_bugs_list.stool:SID31009 1
## FengQ_2015.metaphlan_bugs_list.stool:SID31021 1
## FengQ_2015.metaphlan_bugs_list.stool:SID31071 1
## FengQ_2015.metaphlan_bugs_list.stool:SID31112 1
## FengQ_2015.metaphlan_bugs_list.stool:SID31129 1
## FengQ_2015.metaphlan_bugs_list.stool:SID31159 1
## FengQ_2015.metaphlan_bugs_list.stool:SID31160 1
## FengQ_2015.metaphlan_bugs_list.stool:SID31188 1
## FengQ_2015.metaphlan_bugs_list.stool:SID31219 1
## FengQ_2015.metaphlan_bugs_list.stool:SID31223 1
## FengQ_2015.metaphlan_bugs_list.stool:SID31236 1
## FengQ_2015.metaphlan_bugs_list.stool:SID31237 1
## FengQ_2015.metaphlan_bugs_list.stool:SID31267 1
## FengQ_2015.metaphlan_bugs_list.stool:SID31276 1
## FengQ_2015.metaphlan_bugs_list.stool:SID31285 1
## FengQ_2015.metaphlan_bugs_list.stool:SID31300 1
## FengQ_2015.metaphlan_bugs_list.stool:SID31328 1
## FengQ_2015.metaphlan_bugs_list.stool:SID31333 1
## FengQ_2015.metaphlan_bugs_list.stool:SID31343 1
## FengQ_2015.metaphlan_bugs_list.stool:SID31360 1
## FengQ_2015.metaphlan_bugs_list.stool:SID31367 1
## FengQ_2015.metaphlan_bugs_list.stool:SID31379 1
## FengQ_2015.metaphlan_bugs_list.stool:SID31416 1
## FengQ_2015.metaphlan_bugs_list.stool:SID31428 1
## FengQ_2015.metaphlan_bugs_list.stool:SID31446 1
## FengQ_2015.metaphlan_bugs_list.stool:SID31450 1
## FengQ_2015.metaphlan_bugs_list.stool:SID31452 1
## FengQ_2015.metaphlan_bugs_list.stool:SID31489 1
## FengQ_2015.metaphlan_bugs_list.stool:SID31493 1
## FengQ_2015.metaphlan_bugs_list.stool:SID31512 1
## FengQ_2015.metaphlan_bugs_list.stool:SID31519 1
## FengQ_2015.metaphlan_bugs_list.stool:SID31537 1
## FengQ_2015.metaphlan_bugs_list.stool:SID31549 1
## FengQ_2015.metaphlan_bugs_list.stool:SID31557 1
## FengQ_2015.metaphlan_bugs_list.stool:SID31637 1
## FengQ_2015.metaphlan_bugs_list.stool:SID31685 1
## FengQ_2015.metaphlan_bugs_list.stool:SID31700 1
## FengQ_2015.metaphlan_bugs_list.stool:SID31711 1
## FengQ_2015.metaphlan_bugs_list.stool:SID31714 1
## FengQ_2015.metaphlan_bugs_list.stool:SID31723 1
## FengQ_2015.metaphlan_bugs_list.stool:SID31749 1
## FengQ_2015.metaphlan_bugs_list.stool:SID31750 1
## FengQ_2015.metaphlan_bugs_list.stool:SID31766 1
## FengQ_2015.metaphlan_bugs_list.stool:SID31865 1
## FengQ_2015.metaphlan_bugs_list.stool:SID31866 1
## FengQ_2015.metaphlan_bugs_list.stool:SID31868 1
## FengQ_2015.metaphlan_bugs_list.stool:SID31870 1
## FengQ_2015.metaphlan_bugs_list.stool:SID31871 1
## FengQ_2015.metaphlan_bugs_list.stool:SID31872 1
## FengQ_2015.metaphlan_bugs_list.stool:SID31873 1
## FengQ_2015.metaphlan_bugs_list.stool:SID31874 1
## FengQ_2015.metaphlan_bugs_list.stool:SID31875 1
## FengQ_2015.metaphlan_bugs_list.stool:SID31876 1
## FengQ_2015.metaphlan_bugs_list.stool:SID31877 1
## FengQ_2015.metaphlan_bugs_list.stool:SID31878 1
## FengQ_2015.metaphlan_bugs_list.stool:SID31879 1
## FengQ_2015.metaphlan_bugs_list.stool:SID31880 1
## FengQ_2015.metaphlan_bugs_list.stool:SID31881 1
## FengQ_2015.metaphlan_bugs_list.stool:SID31883 1
## FengQ_2015.metaphlan_bugs_list.stool:SID31884 1
## FengQ_2015.metaphlan_bugs_list.stool:SID530050 1
## FengQ_2015.metaphlan_bugs_list.stool:SID530052 1
## FengQ_2015.metaphlan_bugs_list.stool:SID530055 1
## FengQ_2015.metaphlan_bugs_list.stool:SID530074 1
## FengQ_2015.metaphlan_bugs_list.stool:SID530075 1
## FengQ_2015.metaphlan_bugs_list.stool:SID530119 1
## FengQ_2015.metaphlan_bugs_list.stool:SID530154 1
## FengQ_2015.metaphlan_bugs_list.stool:SID530163 1
## FengQ_2015.metaphlan_bugs_list.stool:SID530167 1
## FengQ_2015.metaphlan_bugs_list.stool:SID530177 1
## FengQ_2015.metaphlan_bugs_list.stool:SID530215 1
## FengQ_2015.metaphlan_bugs_list.stool:SID530227 1
## FengQ_2015.metaphlan_bugs_list.stool:SID530251 1
## FengQ_2015.metaphlan_bugs_list.stool:SID530258 1
## FengQ_2015.metaphlan_bugs_list.stool:SID530295 1
## FengQ_2015.metaphlan_bugs_list.stool:SID530315 1
## FengQ_2015.metaphlan_bugs_list.stool:SID530331 1
## FengQ_2015.metaphlan_bugs_list.stool:SID530364 1
## FengQ_2015.metaphlan_bugs_list.stool:SID530368 1
## FengQ_2015.metaphlan_bugs_list.stool:SID530373 1
## FengQ_2015.metaphlan_bugs_list.stool:SID530394 1
## FengQ_2015.metaphlan_bugs_list.stool:SID530444 1
## FengQ_2015.metaphlan_bugs_list.stool:SID530451 1
## FengQ_2015.metaphlan_bugs_list.stool:SID530890 1
## FengQ_2015.metaphlan_bugs_list.stool:SID531128 1
## FengQ_2015.metaphlan_bugs_list.stool:SID531155 1
## FengQ_2015.metaphlan_bugs_list.stool:SID531248 1
## FengQ_2015.metaphlan_bugs_list.stool:SID531274 1
## FengQ_2015.metaphlan_bugs_list.stool:SID531277 1
## FengQ_2015.metaphlan_bugs_list.stool:SID531281 1
## FengQ_2015.metaphlan_bugs_list.stool:SID531333 1
## FengQ_2015.metaphlan_bugs_list.stool:SID531352 1
## FengQ_2015.metaphlan_bugs_list.stool:SID531361 1
## FengQ_2015.metaphlan_bugs_list.stool:SID531382 1
## FengQ_2015.metaphlan_bugs_list.stool:SID531414 1
## FengQ_2015.metaphlan_bugs_list.stool:SID531416 1
## FengQ_2015.metaphlan_bugs_list.stool:SID531424 1
## FengQ_2015.metaphlan_bugs_list.stool:SID531469 1
## FengQ_2015.metaphlan_bugs_list.stool:SID531766 1
## FengQ_2015.metaphlan_bugs_list.stool:SID531775 1
## FengQ_2015.metaphlan_bugs_list.stool:SID532749 1
## FengQ_2015.metaphlan_bugs_list.stool:SID532779 1
## FengQ_2015.metaphlan_bugs_list.stool:SID532796 1
## FengQ_2015.metaphlan_bugs_list.stool:SID532802 1
## FengQ_2015.metaphlan_bugs_list.stool:SID532826 1
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## YuJ_2015.metaphlan_bugs_list.stool:SZAXPI017583-102 0
## YuJ_2015.metaphlan_bugs_list.stool:SZAXPI017584-108 0
## YuJ_2015.metaphlan_bugs_list.stool:SZAXPI017585-109 0
## YuJ_2015.metaphlan_bugs_list.stool:SZAXPI017586-111 0
## YuJ_2015.metaphlan_bugs_list.stool:SZAXPI017587-113 0
## YuJ_2015.metaphlan_bugs_list.stool:SZAXPI017588-123 0
## YuJ_2015.metaphlan_bugs_list.stool:SZAXPI017589-133 0
## YuJ_2015.metaphlan_bugs_list.stool:SZAXPI017590-136 0
## YuJ_2015.metaphlan_bugs_list.stool:SZAXPI017591-140 0
## YuJ_2015.metaphlan_bugs_list.stool:SZAXPI017592-142 0
## YuJ_2015.metaphlan_bugs_list.stool:SZAXPI017593-158 0
## YuJ_2015.metaphlan_bugs_list.stool:SZAXPI017594-166 0
## YuJ_2015.metaphlan_bugs_list.stool:SZAXPI017595-169 0
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS00146684ST-4-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS00281083ST-3-0 -1
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## ZellerG_2014.metaphlan_bugs_list.stool:CCIS06260551ST-3-0 -1
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## ZellerG_2014.metaphlan_bugs_list.stool:CCIS07648107ST-4-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS09568613ST-4-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS10706551ST-3-0 -1
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## ZellerG_2014.metaphlan_bugs_list.stool:CCIS11362406ST-4-0 -1
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## ZellerG_2014.metaphlan_bugs_list.stool:CCIS71578391ST-4-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS72607085ST-4-0 -1
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## ZellerG_2014.metaphlan_bugs_list.stool:CCIS77252613ST-4-0 -1
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## ZellerG_2014.metaphlan_bugs_list.stool:CCIS82944710ST-20-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS83870198ST-4-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS84543192ST-4-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS85214191ST-3-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS87116798ST-4-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS87167916ST-4-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS87252800ST-4-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS87605453ST-4-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS88007743ST-4-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS88317640ST-4-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS90164298ST-4-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS91228662ST-4-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS93040568ST-20-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS94417875ST-3-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS94603952ST-4-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS95097901ST-4-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS95409808ST-4-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS98482370ST-3-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS98512455ST-4-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS98832363ST-4-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCMD11006829ST-21-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCMD12232071ST-21-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCMD13071240ST-21-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCMD13934959ST-21-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCMD14479708ST-21-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCMD18872694ST-21-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCMD19497912ST-21-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCMD23101338ST-21-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCMD25511638ST-21-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCMD25963797ST-21-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCMD26709089ST-21-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCMD26925580ST-21-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCMD34381688ST-21-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCMD35802077ST-21-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCMD40701343ST-21-0 -1
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## ZellerG_2014.metaphlan_bugs_list.stool:CCMD45988061ST-21-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCMD46222674ST-21-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCMD46947453ST-21-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCMD48236717ST-21-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCMD50071957ST-21-0 -1
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## ZellerG_2014.metaphlan_bugs_list.stool:CCMD60079086ST-21-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCMD63399960ST-21-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCMD64503764ST-21-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCMD64776337ST-21-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCMD72895164ST-21-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCMD74930188ST-21-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCMD79987997ST-21-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCMD82866709ST-21-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCMD86114146ST-21-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCMD86707194ST-21-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCMD87156761ST-21-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCMD88272491ST-21-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCMD90311071ST-21-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCMD93344354ST-21-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCMD95433940ST-21-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCMD96553385ST-21-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:MMPU29365221ST -1
## ZellerG_2014.metaphlan_bugs_list.stool:MMPU68403337ST -1
## ZellerG_2014.metaphlan_bugs_list.stool:MMPU72854103ST -1
## ZellerG_2014.metaphlan_bugs_list.stool:MMPU84450604ST -1
## ZellerG_2014.metaphlan_bugs_list.stool:MMPU99077057ST -1
## studyID2
## FengQ_2015.metaphlan_bugs_list.stool:SID31004 0
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## FengQ_2015.metaphlan_bugs_list.stool:SID31021 0
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## FengQ_2015.metaphlan_bugs_list.stool:SID31700 0
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## FengQ_2015.metaphlan_bugs_list.stool:SID31714 0
## FengQ_2015.metaphlan_bugs_list.stool:SID31723 0
## FengQ_2015.metaphlan_bugs_list.stool:SID31749 0
## FengQ_2015.metaphlan_bugs_list.stool:SID31750 0
## FengQ_2015.metaphlan_bugs_list.stool:SID31766 0
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## FengQ_2015.metaphlan_bugs_list.stool:SID31866 0
## FengQ_2015.metaphlan_bugs_list.stool:SID31868 0
## FengQ_2015.metaphlan_bugs_list.stool:SID31870 0
## FengQ_2015.metaphlan_bugs_list.stool:SID31871 0
## FengQ_2015.metaphlan_bugs_list.stool:SID31872 0
## FengQ_2015.metaphlan_bugs_list.stool:SID31873 0
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## FengQ_2015.metaphlan_bugs_list.stool:SID31881 0
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## HanniganGD_2017.metaphlan_bugs_list.stool:MG100175 1
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## YuJ_2015.metaphlan_bugs_list.stool:SZAXPI017590-136 0
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## YuJ_2015.metaphlan_bugs_list.stool:SZAXPI017592-142 0
## YuJ_2015.metaphlan_bugs_list.stool:SZAXPI017593-158 0
## YuJ_2015.metaphlan_bugs_list.stool:SZAXPI017594-166 0
## YuJ_2015.metaphlan_bugs_list.stool:SZAXPI017595-169 0
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## ZellerG_2014.metaphlan_bugs_list.stool:CCIS90164298ST-4-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS91228662ST-4-0 -1
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## ZellerG_2014.metaphlan_bugs_list.stool:CCIS95097901ST-4-0 -1
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## ZellerG_2014.metaphlan_bugs_list.stool:CCIS98512455ST-4-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS98832363ST-4-0 -1
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## ZellerG_2014.metaphlan_bugs_list.stool:CCMD12232071ST-21-0 -1
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## ZellerG_2014.metaphlan_bugs_list.stool:CCMD18872694ST-21-0 -1
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## ZellerG_2014.metaphlan_bugs_list.stool:CCMD93344354ST-21-0 -1
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## ZellerG_2014.metaphlan_bugs_list.stool:CCMD96553385ST-21-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:MMPU29365221ST -1
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## ZellerG_2014.metaphlan_bugs_list.stool:MMPU72854103ST -1
## ZellerG_2014.metaphlan_bugs_list.stool:MMPU84450604ST -1
## ZellerG_2014.metaphlan_bugs_list.stool:MMPU99077057ST -1
## studyID3
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## YuJ_2015.metaphlan_bugs_list.stool:SZAXPI017595-169 0
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS00146684ST-4-0 -1
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## ZellerG_2014.metaphlan_bugs_list.stool:CCIS72607085ST-4-0 -1
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## ZellerG_2014.metaphlan_bugs_list.stool:CCIS82944710ST-20-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS83870198ST-4-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS84543192ST-4-0 -1
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## ZellerG_2014.metaphlan_bugs_list.stool:CCIS87116798ST-4-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS87167916ST-4-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS87252800ST-4-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS87605453ST-4-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS88007743ST-4-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS88317640ST-4-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS90164298ST-4-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS91228662ST-4-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS93040568ST-20-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS94417875ST-3-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS94603952ST-4-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS95097901ST-4-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS95409808ST-4-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS98482370ST-3-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS98512455ST-4-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCIS98832363ST-4-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCMD11006829ST-21-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCMD12232071ST-21-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCMD13071240ST-21-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCMD13934959ST-21-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCMD14479708ST-21-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCMD18872694ST-21-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCMD19497912ST-21-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCMD23101338ST-21-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCMD25511638ST-21-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCMD25963797ST-21-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCMD26709089ST-21-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCMD26925580ST-21-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCMD34381688ST-21-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCMD35802077ST-21-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCMD40701343ST-21-0 -1
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## ZellerG_2014.metaphlan_bugs_list.stool:CCMD45988061ST-21-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCMD46222674ST-21-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCMD46947453ST-21-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCMD48236717ST-21-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCMD50071957ST-21-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCMD51864103ST-21-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCMD60079086ST-21-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCMD63399960ST-21-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCMD64503764ST-21-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCMD64776337ST-21-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCMD72895164ST-21-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCMD74930188ST-21-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCMD79987997ST-21-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCMD82866709ST-21-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCMD86114146ST-21-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCMD86707194ST-21-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCMD87156761ST-21-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCMD88272491ST-21-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCMD90311071ST-21-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCMD93344354ST-21-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCMD95433940ST-21-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:CCMD96553385ST-21-0 -1
## ZellerG_2014.metaphlan_bugs_list.stool:MMPU29365221ST -1
## ZellerG_2014.metaphlan_bugs_list.stool:MMPU68403337ST -1
## ZellerG_2014.metaphlan_bugs_list.stool:MMPU72854103ST -1
## ZellerG_2014.metaphlan_bugs_list.stool:MMPU84450604ST -1
## ZellerG_2014.metaphlan_bugs_list.stool:MMPU99077057ST -1
## studyID4
## FengQ_2015.metaphlan_bugs_list.stool:SID31004 0
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## HanniganGD_2017.metaphlan_bugs_list.stool:MG100180 0
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##
## $terms
## D_after ~ studyID
## attr(,"variables")
## list(D_after, studyID)
## attr(,"factors")
## studyID
## D_after 0
## studyID 1
## attr(,"term.labels")
## [1] "studyID"
## attr(,"order")
## [1] 1
## attr(,"intercept")
## [1] 1
## attr(,"response")
## [1] 1
## attr(,".Environment")
## <environment: R_GlobalEnv>
##
## attr(,"class")
## [1] "adonis"We can see that, before study effect adjustment, study differences can expalin a total of 7.99% of the variability in microbial abundance profiles, whereas after adjustment this was reduced to 3.04%, though the effect of study is significant in both cases.
5 Meta-analytical differential abundance testing with lm_meta
One of the most common meta-analysis goals is to combine association effects
across batches/studies to identify consistent overall effects. lm_meta
provides a straightforward interface to this task, by first performing
regression analysis in individual batches/studies using the well-validated
Maaslin2 package, and then aggregating results with
established fixed/mixed effect models, realized via the
vegan package. Here, we use lm_meta to test for
consistently differential abundant species between CRC and control samples
across the five studies, while controlling for demographic covariates (gender,
age, BMI). Again, lm_meta returns a list of more than one components.
meta_fits provides the final meta-analytical testing results. See
help(lm_meta) for the meaning of other components.
fit_lm_meta <- lm_meta(feature_abd = CRC_abd,
batch = "studyID",
exposure = "study_condition",
covariates = c("gender", "age", "BMI"),
data = CRC_meta,
control = list(verbose = FALSE))## Warning in lm_meta(feature_abd = CRC_abd, batch = "studyID", exposure = "study_condition", : Covariate gender is missing or has only one non-missing value in the following batches; will be excluded from model for these batches:
## HanniganGD_2017.metaphlan_bugs_list.stool, YuJ_2015.metaphlan_bugs_list.stool## Warning in lm_meta(feature_abd = CRC_abd, batch = "studyID", exposure = "study_condition", : Covariate age is missing or has only one non-missing value in the following batches; will be excluded from model for these batches:
## HanniganGD_2017.metaphlan_bugs_list.stool, YuJ_2015.metaphlan_bugs_list.stool## Warning in lm_meta(feature_abd = CRC_abd, batch = "studyID", exposure = "study_condition", : Covariate BMI is missing or has only one non-missing value in the following batches; will be excluded from model for these batches:
## HanniganGD_2017.metaphlan_bugs_list.stool, YuJ_2015.metaphlan_bugs_list.stoolmeta_fits <- fit_lm_meta$meta_fitsYou’ll note that this command produces a few error messages. This is because for one of the studies the specified covariates were not measured. As the message states, these covariates are not included when analyzing data from that study.
We can visualize the significant (FDR q < 0.05) species associated with CRC in these studies/samples. Comparing them with Figure 1b of Thomas et al. (2019), we can see that many of the significant species do agree.
meta_fits %>%
filter(qval.fdr < 0.05) %>%
arrange(coef) %>%
mutate(feature = factor(feature, levels = feature)) %>%
ggplot(aes(y = coef, x = feature)) +
geom_bar(stat = "identity") +
coord_flip()
6 Identifying discrete population structures with discrete_discover
Clustering analysis of microbial profiles can help identify meaningful
discrete population subgroups (Ravel et al. 2011), but must be carried out
carefully with validations to ensure that the identified structures are
consistent (Koren et al. 2013). discrete_discover provides the functionality to
use prediction strength (Tibshirani and Walther 2005) to evaluate discrete
clustering structures within individual microbial studies, as well as a
“generalized prediction strength” to evaluate their reproducibility in
other studies. These jointly provide meta-analytical evidence for
(or against) identifying discrete population structures in microbial profiles.
Check help(discrete_discover) to see more details on the method and additional
options. We can contrast discrete structure (clusters) with continuous structure (which will be overviewed in the next section):
The gut microbiome is known to form gradients rather than discrete clusters
(Koren et al. 2013). Here we use discrete_discover to evaluate clustering
structures among control samples in the five stool studies. It’s worth noting that this function takes a distance/dissimilarity matrix as an input, rather than the abundance table.
control_meta <- subset(CRC_meta, study_condition == "control")
control_abd_adj <- CRC_abd_adj[, rownames(control_meta)]
D_control <- vegdist(t(control_abd_adj))
fit_discrete <- discrete_discover(D = D_control,
batch = "studyID",
data = control_meta,
control = list(k_max = 8,
verbose = FALSE))The internal_mean and internal_sd components of fit_discrete are matrices
that provide internal evaluation statistics (prediction strength) for each
batch (column) and evaluated number of clusters (row). Similarly,
external_mean and external_sd provide external evaluation statistics (
generalized prediction strenght). Evidence for existence of discrete structures
would be a “peaking” of the mean statistics at a particular cluster number.
Here, for easier examination of such a pattern, we visualize the results
for the largest study, ZellerG_2014. Note that visualization for all studies
are by default automatically generated and saved to the output file
“diagnostic_discrete.pdf”.
study_id = "ZellerG_2014.metaphlan_bugs_list.stool"
internal <- data.frame(K = 2:8,
statistic = fit_discrete$internal_mean[, study_id],
se = fit_discrete$internal_se[, study_id],
type = "internal")
external <- data.frame(K = 2:8,
statistic = fit_discrete$external_mean[, study_id],
se = fit_discrete$external_se[, study_id],
type = "external")
rbind(internal, external) %>%
ggplot(aes(x = K, y = statistic, color = type)) +
geom_point(position = position_dodge(width = 0.5)) +
geom_line(position = position_dodge(width = 0.5)) +
geom_errorbar(aes(ymin = statistic - se, ymax = statistic + se),
position = position_dodge(width = 0.5), width = 0.5) +
ggtitle("Evaluation of discrete structure in control stool microbiome (ZellerG_2014)")
The decreasing trend for both the internal and external statistics along with number of clusters (K) suggests that discrete structures cannot be well-established. To provide a positive example, we examine the two vaginal microbiome studies provided by curatedMetagenomicData, as the vaginal microbiome is known to have distinct subtypes (Ravel et al. 2011). Again, we pre-formatted these datasets for easy access, but you can recreate them from curatedMetagenomicData with the commented out scripts.
data("vaginal_abd", "vaginal_meta")
D_vaginal <- vegdist(t(vaginal_abd))
fit_discrete_vag <- discrete_discover(D = D_vaginal,
batch = "studyID",
data = vaginal_meta,
control = list(verbose = FALSE,
k_max = 8))
hmp_id = "HMP_2012.metaphlan_bugs_list.vagina"
data.frame(K = 2:8,
statistic = fit_discrete_vag$internal_mean[, hmp_id],
se = fit_discrete_vag$internal_se[, hmp_id]) %>%
ggplot(aes(x = K, y = statistic)) +
geom_point() +
geom_line() +
geom_errorbar(aes(ymin = statistic - se,
ymax = statistic + se),
width = 0.5) +
ggtitle("Evaluation of discrete structure in vaginal microbiome (HMP_2012)")
We can see that for the vaginal microbiome, discrete_discover suggests the
existence of five clusters. Here we examine only the internal metrics of
HMP_2012 as the other study (FerrettiP_2018) has only
19
samples.
7 Identifying continuous population structures with continuous_discover
Population structure in the microbiome can manifest as gradients rather than
discrete clusters, such as dominant phyla trade-off or disease-associated
dysbiosis. continuous_discover provide functionality to identify such
structures as well as to validate them with meta-analysis. We again evaluate
these continuous structures in control samples of the five studies.
Much like adjust_batch and lm_meta, continuous_discover also takes as input feature-by-sample abundances. The control argument offers many tuning parameters and here we set one of them, var_perc_cutoff, to 0.5, which asks the method to include top principal components within each batch that in total explain at least 50% of the total variability in the batch. See help(continuous_discover) for more details on the tuning parameters and their interpretations.
fit_continuous <- continuous_discover(feature_abd = control_abd_adj,
batch = "studyID",
data = control_meta,
control = list(var_perc_cutoff = 0.5,
verbose = FALSE))We can visualize the identified continuous structure scores in at least two ways: first, to examine their top contributing microbial features, to get an idea of what the score is characterizing, and second, to overlay the continuous scores with an ordination visualization. Here we perform these visualizations on the first identified continuous score.
loading <- data.frame(feature = rownames(fit_continuous$consensus_loadings),
loading1 = fit_continuous$consensus_loadings[, 1])
loading %>%
arrange(-abs(loading1)) %>%
slice(1:20) %>%
arrange(loading1) %>%
mutate(feature = factor(feature, levels = feature)) %>%
ggplot(aes(x = feature, y = loading1)) +
geom_bar(stat = "identity") +
coord_flip() +
ggtitle("Features with top loadings")
mds <- cmdscale(d = D_control)
colnames(mds) <- c("Axis1", "Axis2")
as.data.frame(mds) %>%
mutate(score1 = fit_continuous$consensus_scores[, 1]) %>%
ggplot(aes(x = Axis1, y = Axis2, color = score1)) +
geom_point() +
coord_fixed()
From ordination we see that the first continuos score indeed represent strong variation across these stool samples. From the top loading features we can see that this score strongly represents a Bacteroidetes (the Bacteroides species) versus Firmicutes (the Ruminococcus species) tradeoff.
8 Sessioninfo
sessionInfo()## R version 4.2.0 RC (2022-04-19 r82224)
## Platform: x86_64-pc-linux-gnu (64-bit)
## Running under: Ubuntu 20.04.4 LTS
##
## Matrix products: default
## BLAS: /home/biocbuild/bbs-3.15-bioc/R/lib/libRblas.so
## LAPACK: /home/biocbuild/bbs-3.15-bioc/R/lib/libRlapack.so
##
## locale:
## [1] LC_CTYPE=en_US.UTF-8 LC_NUMERIC=C
## [3] LC_TIME=en_GB LC_COLLATE=C
## [5] LC_MONETARY=en_US.UTF-8 LC_MESSAGES=en_US.UTF-8
## [7] LC_PAPER=en_US.UTF-8 LC_NAME=C
## [9] LC_ADDRESS=C LC_TELEPHONE=C
## [11] LC_MEASUREMENT=en_US.UTF-8 LC_IDENTIFICATION=C
##
## attached base packages:
## [1] stats graphics grDevices utils datasets methods base
##
## other attached packages:
## [1] vegan_2.6-2 lattice_0.20-45 permute_0.9-7 ggplot2_3.3.5
## [5] dplyr_1.0.8 magrittr_2.0.3 MMUPHin_1.10.0 BiocStyle_2.24.0
##
## loaded via a namespace (and not attached):
## [1] nlme_3.1-157 prabclus_2.3-2 tools_4.2.0
## [4] bslib_0.3.1 utf8_1.2.2 R6_2.5.1
## [7] metafor_3.4-0 DBI_1.1.2 mgcv_1.8-40
## [10] colorspace_2.0-3 nnet_7.3-17 withr_2.5.0
## [13] tidyselect_1.1.2 compiler_4.2.0 textshaping_0.3.6
## [16] cli_3.3.0 logging_0.10-108 biglm_0.9-2.1
## [19] labeling_0.4.2 bookdown_0.26 sass_0.4.1
## [22] diptest_0.76-0 scales_1.2.0 DEoptimR_1.0-11
## [25] mvtnorm_1.1-3 robustbase_0.95-0 pbapply_1.5-0
## [28] systemfonts_1.0.4 stringr_1.4.0 digest_0.6.29
## [31] rmarkdown_2.14 pkgconfig_2.0.3 htmltools_0.5.2
## [34] lpsymphony_1.24.0 fastmap_1.1.0 highr_0.9
## [37] rlang_1.0.2 jquerylib_0.1.4 farver_2.1.0
## [40] generics_0.1.2 jsonlite_1.8.0 mclust_5.4.9
## [43] modeltools_0.2-23 metadat_1.2-0 Matrix_1.4-1
## [46] Rcpp_1.0.8.3 munsell_0.5.0 fansi_1.0.3
## [49] lifecycle_1.0.1 stringi_1.7.6 yaml_2.3.5
## [52] Maaslin2_1.10.0 mathjaxr_1.6-0 MASS_7.3-57
## [55] flexmix_2.3-17 grid_4.2.0 parallel_4.2.0
## [58] crayon_1.5.1 cowplot_1.1.1 splines_4.2.0
## [61] hash_2.2.6.2 magick_2.7.3 knitr_1.38
## [64] pillar_1.7.0 igraph_1.3.1 optparse_1.7.1
## [67] fpc_2.2-9 stats4_4.2.0 glue_1.6.2
## [70] evaluate_0.15 BiocManager_1.30.17 vctrs_0.4.1
## [73] gtable_0.3.0 getopt_1.20.3 purrr_0.3.4
## [76] tidyr_1.2.0 kernlab_0.9-30 assertthat_0.2.1
## [79] xfun_0.30 class_7.3-20 ragg_1.2.2
## [82] pcaPP_2.0-1 tibble_3.1.6 cluster_2.1.3
## [85] ellipsis_0.3.2References
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Ravel, Jacques, Pawel Gajer, Zaid Abdo, G Maria Schneider, Sara SK Koenig, Stacey L McCulle, Shara Karlebach, et al. 2011. “Vaginal Microbiome of Reproductive-Age Women.” Proceedings of the National Academy of Sciences 108 (Supplement 1): 4680–7.
Tang, Zheng-Zheng, Guanhua Chen, and Alexander V Alekseyenko. 2016. “PERMANOVA-S: Association Test for Microbial Community Composition That Accommodates Confounders and Multiple Distances.” Bioinformatics 32 (17): 2618–25.
Thomas, Andrew Maltez, Paolo Manghi, Francesco Asnicar, Edoardo Pasolli, Federica Armanini, Moreno Zolfo, Francesco Beghini, et al. 2019. “Metagenomic Analysis of Colorectal Cancer Datasets Identifies Cross-Cohort Microbial Diagnostic Signatures and a Link with Choline Degradation.” Nature Medicine 25 (4): 667.
Tibshirani, Robert, and Guenther Walther. 2005. “Cluster Validation by Prediction Strength.” Journal of Computational and Graphical Statistics 14 (3): 511–28.