DOI: 10.18129/B9.bioc.RolDE    

This package is for version 3.15 of Bioconductor; for the stable, up-to-date release version, see RolDE.

RolDE: Robust longitudinal Differential Expression

Bioconductor version: 3.15

RolDE detects longitudinal differential expression between two conditions in noisy high-troughput data. Suitable even for data with a moderate amount of missing values.RolDE is a composite method, consisting of three independent modules with different approaches to detecting longitudinal differential expression. The combination of these diverse modules allows RolDE to robustly detect varying differences in longitudinal trends and expression levels in diverse data types and experimental settings.

Author: Tommi Valikangas [cre, aut]

Maintainer: Tommi Valikangas <tsvali at>

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biocViews DifferentialExpression, Proteomics, Regression, Software, StatisticalMethod, TimeCourse
Version 1.0.0
In Bioconductor since BioC 3.15 (R-4.2) (0.5 years)
License GPL-3
Depends R (>= 4.2.0)
Imports stats, methods, ROTS, matrixStats, foreach, parallel, doParallel, doRNG, rngtools, SummarizedExperiment, nlme, qvalue, grDevices, graphics, utils
Suggests knitr, printr, rmarkdown, testthat
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