ONEIL_screening_data {synergyfinder} | R Documentation |
A 2-drug combination screening data on cancer cell lines. It is from publication [(O'Neil, 2016)](https://pubmed.ncbi.nlm.nih.gov/26983881/). It contains 2 blocks, one is synergistic and the other is antagonistic.
A data frame with the following columns: "block_id", "drug1", "drug2", "cell_line_name", "conc1", "conc2", "response", "conc_unit1", "conc_unit2"
O’Neil, J., Benita, Y., Feldman, I., Chenard, M., Roberts, B., Liu, Y., Li, J., Kral, A., Lejnine, S., Loboda, A., Arthur, W., Cristescu, R., Haines, B.B., Winter, C., Zhang, T., Bloecher, A., Shumway, S.D., 2016. An Unbiased Oncology Compound Screen to Identify Novel Combination Strategies. Mol Cancer Ther 15, 1155–1162.