methylation_specificity {spiky}R Documentation

compute methylation specificity for spike-in standards

Description

In a cfMeDIP experiment, the yield of methylated fragments should be >95% (ideally 98-99%) due to the nature of the assay.

Usage

methylation_specificity(ssb_res, spike)

Arguments

ssb_res

output object from scan_spiked_bam

spike

spike contig database, if needed (e.g. data(spike))

Value

         list with median and mean coverage across spike contigs

Examples

data(ssb_res)
data(spike, package="spiky")
methylation_specificity(ssb_res,spike=spike)


[Package spiky version 0.99.999 Index]